ath Chatham House Forum: Are Humans Psychologically Wired to Fight? By f1.media.brightcove.com Published On :: Tue, 05 Jun 2018 00:00:00 +0100 Full Article
ath Chatham House Forum: Is the Welfare State Fit for Purpose? By f1.media.brightcove.com Published On :: Thu, 13 Sep 2018 00:00:00 +0100 Full Article
ath Chatham House Forum: Does Religion Incite Violence? By f1.media.brightcove.com Published On :: Thu, 18 Oct 2018 00:00:00 +0100 Full Article
ath Chatham House Primer: National Populism By f1.media.brightcove.com Published On :: Wed, 24 Oct 2018 00:00:00 +0100 Full Article
ath Chatham House Prize 2018: The Committee to Protect Journalists By f1.media.brightcove.com Published On :: Wed, 28 Nov 2018 00:00:00 +0000 Full Article
ath Undercurrents: Episode 28 – The History of Women at Chatham House By f1.media.brightcove.com Published On :: Thu, 07 Mar 2019 00:00:00 +0000 Full Article
ath Chatham House Primer: ‘Leaving on WTO Terms’ By f1.media.brightcove.com Published On :: Mon, 11 Mar 2019 00:00:00 +0000 Full Article
ath Chatham House Primer: Making Change By f1.media.brightcove.com Published On :: Thu, 04 Apr 2019 00:00:00 +0100 Full Article
ath A Path Forward for US Politics By f1.media.brightcove.com Published On :: Mon, 17 Jun 2019 00:00:00 +0100 Full Article
ath Leadership in the 21st Century: Jim O’Neill, Chatham House By f1.media.brightcove.com Published On :: Thu, 25 Jul 2019 00:00:00 +0100 Full Article
ath Chatham House Primer: Democratic Socialism By f1.media.brightcove.com Published On :: Thu, 13 Feb 2020 00:00:00 +0000 Full Article
ath Undercurrents: Episode 51 - Preparing for Pandemics, and Gandhi's Chatham House Speech By brightcove.hs.llnwd.net Published On :: Thu, 30 Apr 2020 00:00:00 +0100 Full Article
ath Undercurrents: Episode 62 - 100 Years of Chatham House By brightcove.hs.llnwd.net Published On :: Thu, 09 Jul 2020 00:00:00 +0100 Full Article
ath Thematic review series: The Pathogenesis of Atherosclerosis The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL By www.jlr.org Published On :: 2004-06-01 Mohamad NavabJun 1, 2004; 45:993-1007Thematic Reviews Full Article
ath Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death By www.jlr.org Published On :: 2006-12-01 Nica M. BorradaileDec 1, 2006; 47:2726-2737Research Articles Full Article
ath Thematic review series: The Pathogenesis of Atherosclerosis. Effects of infection and inflammation on lipid and lipoprotein metabolism mechanisms and consequences to the host By www.jlr.org Published On :: 2004-07-01 Weerapan KhovidhunkitJul 1, 2004; 45:1169-1196Thematic Reviews Full Article
ath Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice By www.jlr.org Published On :: 1995-11-01 RK TangiralaNov 1, 1995; 36:2320-2328Articles Full Article
ath Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E By www.jlr.org Published On :: 1999-01-01 Robert W. MahleyJan 1, 1999; 40:1-16Reviews Full Article
ath Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis By www.jlr.org Published On :: 1996-04-01 IJ GoldbergApr 1, 1996; 37:693-707Reviews Full Article
ath The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function By www.jlr.org Published On :: 1992-02-01 JP SegrestFeb 1, 1992; 33:141-166Reviews Full Article
ath Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans By www.jlr.org Published On :: 2005-11-01 Saverio CintiNov 1, 2005; 46:2347-2355Research Articles Full Article
ath The Committee to Protect Journalists named winner of the Chatham House Prize 2018 By www.chathamhouse.org Published On :: Fri, 05 Oct 2018 10:53:06 +0000 The Committee to Protect Journalists named winner of the Chatham House Prize 2018 News Release sysadmin 5 October 2018 The Committee to Protect Journalists (CPJ) has been voted the winner of this year’s Chatham House Prize. Full Article
ath Chatham House awarded major centenary grant to establish Stavros Niarchos Foundation Wing By www.chathamhouse.org Published On :: Tue, 16 Apr 2019 11:32:22 +0000 Chatham House awarded major centenary grant to establish Stavros Niarchos Foundation Wing News Release sysadmin 16 April 2019 Chatham House has been awarded a transformational £10m grant ahead of its upcoming 2020 centenary. Full Article
ath Chatham House appoints Tim Benton as Research Director for Energy, Environment and Resources By www.chathamhouse.org Published On :: Thu, 30 May 2019 08:44:55 +0000 Chatham House appoints Tim Benton as Research Director for Energy, Environment and Resources News Release sysadmin 30 May 2019 Chatham House is pleased to announce that Professor Tim Benton has been appointed as research director of the Energy, Environment and Resources Department. Full Article
ath Chatham House appoints Rob Yates as the new head of the Centre on Global Health Security By www.chathamhouse.org Published On :: Thu, 27 Jun 2019 09:35:01 +0000 Chatham House appoints Rob Yates as the new head of the Centre on Global Health Security News Release sysadmin 27 June 2019 Chatham House is pleased to announce that Rob Yates has been appointed as head of the Centre on Global Health Security. Full Article
ath Chatham House Commission on Democracy and Technology in Europe By www.chathamhouse.org Published On :: Thu, 25 Jul 2019 14:47:34 +0000 Chatham House Commission on Democracy and Technology in Europe News Release sysadmin 25 July 2019 Our project on Democracy and Technology in Europe is now entering its final phase. Now we want your help in shaping the final report. Full Article
ath Sir David Attenborough and the BBC Studios Natural History Unit awarded Chatham House Prize 2019 for ocean advocacy By www.chathamhouse.org Published On :: Mon, 18 Nov 2019 13:13:54 +0000 Sir David Attenborough and the BBC Studios Natural History Unit awarded Chatham House Prize 2019 for ocean advocacy News Release sysadmin 18 November 2019 The 2019 Chatham House Prize is awarded to Sir David Attenborough and Julian Hector, head of BBC Studios Natural History Unit, for the galvanizing impact of the Blue Planet II series on tackling ocean plastic pollution. Full Article
ath COVID-19 and Chatham House By www.chathamhouse.org Published On :: Wed, 04 Mar 2020 16:56:10 +0000 COVID-19 and Chatham House News Release sysadmin 4 March 2020 Chatham House continues to operate during the coronavirus pandemic. Full Article
ath Chatham House Prize: Malawi Judges Win for Election Work By www.chathamhouse.org Published On :: Fri, 23 Oct 2020 11:15:44 +0000 Chatham House Prize: Malawi Judges Win for Election Work News Release NCapeling 23 October 2020 Malawi’s constitutional court judges have won the 2020 Chatham House Prize in recognition of their 'courage and independence in the defence of democracy'. Full Article
ath New Chatham House History Examines our Defining Moments By www.chathamhouse.org Published On :: Mon, 18 Jan 2021 16:38:45 +0000 New Chatham House History Examines our Defining Moments News Release NCapeling 18 January 2021 'A History of Chatham House: its People and Influence from the 1920s to the 2020s' will examine the impact on policymaking of our first 100 years. Full Article
ath Chatham House welcomes 2022 interns By www.chathamhouse.org Published On :: Wed, 11 May 2022 13:30:32 +0000 Chatham House welcomes 2022 interns News release jon.wallace 11 May 2022 Internships provide learning opportunities about shaping policy, influencing debate and creating real change. Chatham House is excited to welcome the second cohort to the Molchanov Sustainability Internship Programme. Introduced in January 2021, the programme has been made possible following the gift of Pavel Molchanov, to support the next generation of leaders in sustainability. The internships grant invaluable, practical learning opportunities about shaping policy, influencing debate and creating real change towards a sustainable future. Alis Martin, Internships and Outreach Manager at Chatham House, said: ‘We are delighted to welcome the second cohort to the Molchanov Sustainability Internship Programme. This cohort brings a diversity of new and invaluable perspectives and ideas to the work of our programmes. ‘Over the course of 12 weeks, interns will be working alongside internationally respected experts in Chatham House programmes, exploring issues of sustainability through the lenses of climate change, the circular economy, conflict prevention, emerging technology, global health, governance, human rights, security policy, sustainable cities and sustainable finance. ‘Fostering sustainable and equitable growth and engaging the next generation of policy leaders is central to Chatham House’s vision. We are committed to providing the best experience and opportunities to our interns who share an interest in pursuing a career in the field of sustainability. ‘It is crucial that we incorporate the views and knowledge of those who will be affected most in the future and I very much look forward to seeing the innovative and impactful ideas that will undoubtedly result from their work.’ Mr Molchanov said: ‘Recent headlines around the world underscore the importance of taking the broadest possible perspective on sustainability. Energy supply concerns, rising food prices, and continued pandemic pressure are all interconnected with climate issues. I look forward to hearing about the work in which this year’s internship participants engage.’ Jerome Puri, intern, Middle East and North Africa Programme, said: ‘I applied for this internship to gain a holistic insight into the coordination of a policy institute and to understand how Chatham House promotes international cooperation and accountable governance around the world. Chatham House offers an unparalleled opportunity to contribute to projects on frontier issues facing the MENA region and develop a diverse range of skills ranging from project management and communications to policy-oriented research skills.’ Obioma Egemonye, intern, Africa Programme, said: ‘I was particularly interested in joining the Africa Programme at Chatham House after learning an immeasurable amount from their work on the Social Norms and Accountable Governance (SNAG) research for my undergraduate dissertation. I am most looking forward to attending the variety of events held by Chatham House and the Africa programme specifically.’ Valdone Sniukaite, intern, Europe Programme, said: ‘I am excited to be joining the Europe Programme team and getting exposure to the inner workings of a policy and research think tank. I’m mostly looking forward to building my organizational skill set by working on the Belvedere Forum and using the opportunity of being around experts in the field of international affairs to broaden my knowledge.’ Lucile de Laforcade, intern, Queen Elizabeth II Academy for Leadership in International Affairs, said: ‘As part of the Academy, I am able to work at the crossroads of research, leadership, international affairs and personal development. This makes the Academy a place of constant challenge to find innovative, sustainable solutions, and emulate new ideas. As an aspiring academic, this is particularly empowering! I am hoping to gain new skills, further develop independent thinking, and cultivate my own research interests in the vibrant environment of a leading policy institute.’ Katie McCann, intern, Communications and Publishing, said: ‘I’m really interested in youth engagement in international politics so I’m very excited to be working on the Common Futures Conversations platform which brings young people across Europe and Africa into the debate on the pressing global issues of our time. I hope my time at Chatham House will expose me to people of different backgrounds and beliefs which will encourage me to engage even more critically with international affairs.’ Rachael Mullally, intern, International Law Programme, said: ‘What I admire most about the International Law Programme here is its position as a dependable yet experimental source on global governance debates. I am especially excited to get working on the Human Rights Pathways Project, focusing on tangible ideas as to how the human rights framework can evolve to meet power shifts between states and non-state actors.’ Elia Duran-Smith, intern, International Security Programme, said: ‘I was particularly drawn to this internship because of the thematic focuses of the programme around nuclear security and emerging technologies in the sector, which are fundamental to understanding the future of the global security environment. I am looking forward to learning more about these topics while developing and expanding my research and writing skills, as well as gaining an understanding of project management and how Chatham House engages with stakeholders on policy.’ Rory Selvey, intern, Sustainability Accelerator, said: ‘For me, speeding up the transition towards a fairer, low-carbon society is one of most important global challenges. I’m really excited to be an intern at the Sustainability Accelerator, collaborating with different teams and exploring innovation solutions to this challenge. Chatham House will help me develop vital knowledge and skills, acting as a fantastic springboard for a potential career in sustainable finance, macroeconomics, or international development.’ Bruna Miguel, intern, Environment and Society Programme, said: ‘Being an intern in the Environment and Society Programme will give me the opportunity to further investigate how these issues relate and how we can achieve true sustainability. I look forward to learning from the experts in the area that I will meet (and hopefully find a dissertation topic!).’ Ritvij Singh, intern, Global Health Programme, said: ‘My view of healthcare delivery is from the frontlines as a medical doctor. I applied to this internship to widen my perspective and get an insight into the institutions that will help facilitate universal health. I will use this experience to pursue a career in global health.’ For more information about the internships, please contact Alis Martin. Full Article
ath A novel stress-inducible CmtR-ESX3-Zn2+ regulatory pathway essential for survival of Mycobacterium bovis under oxidative stress [Microbiology] By www.jbc.org Published On :: 2020-12-11T00:06:20-08:00 Reactive oxygen species (ROS) are an unavoidable host environmental cue for intracellular pathogens such as Mycobacterium tuberculosis and Mycobacterium bovis; however, the signaling pathway in mycobacteria for sensing and responding to environmental stress remains largely unclear. Here, we characterize a novel CmtR-Zur-ESX3-Zn2+ regulatory pathway in M. bovis that aids mycobacterial survival under oxidative stress. We demonstrate that CmtR functions as a novel redox sensor and that its expression can be significantly induced under H2O2 stress. CmtR can physically interact with the negative regulator Zur and de-represses the expression of the esx-3 operon, which leads to Zn2+ accumulation and promotion of reactive oxygen species detoxication in mycobacterial cells. Zn2+ can also act as an effector molecule of the CmtR regulator, using which the latter can de-repress its own expression for further inducing bacterial antioxidant adaptation. Consistently, CmtR can induce the expression of EsxH, a component of esx-3 operon involved in Zn2+ transportation that has been reported earlier, and inhibit phagosome maturation in macrophages. Lastly, CmtR significantly contributes to bacterial survival in macrophages and in the lungs of infected mice. Our findings reveal the existence of an antioxidant regulatory pathway in mycobacteria and provide novel information on stress-triggered gene regulation and its association with host–pathogen interaction. Full Article
ath Coronavirus and trade war pushing China to focus on fixing economy rather than leading world order By www.chathamhouse.org Published On :: Wed, 10 Jun 2020 08:49:06 +0000 Source The South China Morning Post URL https://www.scmp.com/comment/opinion/article/3087713/coronavirus-and-trade-war-p... Release date 08 June 2020 Expert Dr Yu Jie In the news type Op-ed Hide date on homepage Full Article
ath Mathematical model of the spread of a pandemic like COVID-19 By www.ams.org Published On :: Tue, 01 Oct 2024 14:21 EDT A. G. Sergeev, A. Kh. Khachatryan and Kh. A. Khachatryan Trans. Moscow Math. Soc. 83 (), 55-65. Abstract, references and article information Full Article
ath Mixing Math and Cooking By www.ams.org Published On :: Mon, 25 Jan 2021 14:38:14 -0400 Math's connection with cooking extends beyond the mathematical constant that sounds like a dessert. For example, using differential equations to model fluid flow and heat transfer, research teams have found how spaghetti curls as it's cooked, how to rotate a pan to make the perfect crepe (thin pancake), and the temperature setting to get the perfect steak. Mathematics helps understand cooking, and parallels it in that following a recipe can lead to good results, but asking questions like "What if we tried this?" can lead to a masterpiece. Eugenia Cheng talks about the mathematics of cooking and baking. Full Article
ath Doing the Math By www.ams.org Published On :: Mon, 24 May 2021 14:38:14 -0400 Math may sometimes seem as if it's comprised of countless meaningless unconnected exercises, but in reality, it's much more. It's figuring out how to do something, and, even better, why something works the way it does. The math you're doing now can open doors for you so that you can answer deep questions yourself about a subject or idea that you're interested in. Give those questions a shot and perhaps someday also help others solve their problems. Five mathematicians (Alexander Diaz-Lopez, Trachette Jackson, Francis Su, Erika Tatiana Camacho, and Deanna Haunsperger) talk about what mathematics means to them. Full Article
ath Using Math to Support Cancer Research By www.ams.org Published On :: Thu, 29 Dec 2022 2:39:14 -0400 Stacey Finley from University of Southern California discusses how mathematical models support the research of cancer biology. Cancer research is a crucial job, but a difficult one. Tumors growing inside the human body are affected by all kinds of factors. These conditions are difficult (if not impossible) to recreate in the lab, and using real patients as subjects can be painful and invasive. Mathematical models give cancer researchers the ability to run experiments virtually, testing the effects of any number of factors on tumor growth and other processes — all with far less money and time than an experiment on human subjects or in the lab would use. Full Article
ath Giving Health Care Policy a Dose of Mathematics By www.ams.org Published On :: Wed, 5 Apr 2023 10:49:14 -0400 Imelda Flores Vazquez from Econometrica, Inc. explains how economists use mathematics to evaluate the efficacy of health care policies. When a hospital or government wants to adjust their health policies — for instance, by encouraging more frequent screenings for certain diseases — how do they know whether their program will work or not? If the service has already been implemented elsewhere, researchers can use that data to estimate its effects. But if the idea is brand-new, or has only been used in very different settings, then it's harder to predict how well the new program will work. Luckily, a tool called a microsimulation can help researchers make an educated guess. Full Article
ath Smashing Particles up Against Mathematics By www.ams.org Published On :: Fri, 8 Mar 2024 14:33:14 -0400 Dr. Abiy Tasissa of Tufts University, discusses the mathematics he and colleagues used to study particle collider data, including optimal transport and optimization. Collider physics often result in distributions referred to as jets. Dr. Tasissa and his team used "Earth Mover's Distance" and other mathematical tools to study the shape of jets. "It is interesting for me to see how mathematics can be applied to study these fundamental problems answering fundamental equations in physics, not only at the level of formulating new ideas, which is, in this particular case, a notion of distance, but also how the importance of designing fast optimization algorithms to be able to actually compute these distances," says Dr. Tasissa. Full Article
ath The space of vectored hyperbolic surfaces is path-connected By www.ams.org Published On :: Fri, 04 Oct 2024 16:24 EDT Sangsan Warakkagun Conform. Geom. Dyn. 28 (), 115-130. Abstract, references and article information Full Article
ath Mathematical Analyses of Decisions, Voting and Games By www.ams.org Published On :: Mon, 04 Mar 2024 14:51 EST Michael A. Jones, David McCune and Jennifer M. Wilson, editors. American Mathematical Society, 2024, CONM, volume 795, approx. 208 pp. ISBN: 978-1-4704-6978-8 (print), 978-1-4704-7608-3 (online). This volume contains the proceedings of the virtual AMS Special Session on Mathematics of Decisions, Elections and Games, held on April 8,... Full Article
ath Separating path systems of almost linear size By www.ams.org Published On :: Thu, 31 Oct 2024 16:22 EDT Shoham Letzter Trans. Amer. Math. Soc. 377 (), 5583-5615. Abstract, references and article information Full Article
ath UC Irvine Wins 2025 AMS Award for an Exemplary Program in a Mathematics Department By www.ams.org Published On :: Tue, 12 Nov 2024 00:00:00 EST The Math Community Educational Outreach (Math CEO) program at the University of California, Irvine (UCI) will receive the 2025 AMS Award for an Exemplary Program or Achievement in a Mathematics Department. Founded in 2014, UCI’s Math CEO is an after-school math enrichment program aimed at increasing the number of talented students in STEM from diverse backgrounds by fostering mathematical exploration, mentor development, and community engagement. Participants in the Math CEO program at University of California, Irvine Credit: Jennifer Tran, Math CEO outreach assistant From the citation The University of California, Irvine (UCI) Math CEO program is recognized for its exceptional contributions to the mathematics community and society at large. Established in 2014 by professors Alessandra Pantano and Li-Sheng Tseng, Math CEO targets students from Title I middle schools, providing them with a high-quality after-school math enrichment program. This program brings middle-school students to the UCI campus to work in small groups with undergraduate mentors, many of whom are also from historically marginalized groups, to engage in challenging mathematical tasks and encourage exploration. From September 2019 to June 2024, Math CEO engaged a total of 1,221 youth, with 48.6% identifying as female. The ethnic background of the participants was predominantly Latinx (93.5%), with smaller representations of Asian, white, and multiethnic students. In the same five-year period, Math CEO engaged 553 undergraduate mentors, 62.2% of whom were female. The mentors’ ethnic backgrounds were diverse, with significant representation of Asian (52%) and Latinx (30%) students. The undergraduate mentors, many of whom pursue careers in education, receive training in culturally responsive teaching practices and equity in education, significantly impacting their professional development. In a post-survey, 52.3% of the undergraduate mentors expressed interest in teaching or working in education and 45.9% were likely to pursue professions working with children or families. Recognizing the central role of families in supporting Latinx youth, Math CEO involves parents through bilingual workshops that enhance community awareness of college pathways and financial opportunities. Math CEO has been the foundation for numerous research projects in mathematics education, supported by NSF grants, leading to publications and program growth. The program’s success is evident in its expansion to high schools and other regions in Southern California, including a new branch at California State University, Dominguez Hills. Math CEO continues to make a substantial impact on underserved youth, demonstrating a model of systemic, reproducible change that can be implemented by others. Response of Alessandra Pantano, UCI Math CEO I am deeply honored to receive the AMS Award for an Exemplary Program in a Mathematics Department on behalf of the UCI Math CEO team. This wonderful award recognizes the work of many colleagues, graduate students, and undergraduate students in developing and delivering the UCI Math Community Educational Outreach (Math CEO) program. For over a decade, Math CEO has provided creative and culturally responsive math enrichment opportunities for hundreds of underprivileged middle-school students, many of which have since “graduated” to high school or even college. Leading this exceptional and dedicated team of volunteers has been the highest pride of my professional life. A special thanks to my partners-in-crime, Prof. Li-Sheng Tseng, codirector of Math CEO, and former graduate student Andres Forero Cuervo, academic coordinator for Math CEO: We could have never done this without you. I look forward to pushing this activity forward and continuing to dedicate my energy to help kids in our county find the way to express their potential – in math and in life! A big thanks to the colleagues who nominated us and to the AMS for recognizing our efforts. History of the program The UC Irvine Math Community Educational Outreach (Math CEO) program was founded in 2014 by math faculty Alessandra Pantano and Li-Sheng Tseng in collaboration with Santa Ana Unified math teacher Jasmina Matasovic. The founders shared a belief that low standardized test scores in underserved communities do not reflect students’ interest and potential to succeed in STEM. Math CEO runs free, weekly, after-school math enrichment sessions, welcoming all youth regardless of math achievement. Starting with only 25 students from one middle school, the program has grown and engaged nearly two thousand students in all, from multiple school districts in Southern California. About the award The annual AMS Award for an Exemplary Program or Achievement in a Mathematics Department was established in 2004 and first given in 2006. This award recognizes a department which has distinguished itself by undertaking an unusual or particularly effective program of value to the mathematics community, internally or in relation to the rest of society. Departments of mathematical sciences in North America that offer at least a bachelor’s degree in mathematical sciences are eligible. The award amount is currently $5,000. The award will be presented at the 2025 Joint Mathematics Meetings in Seattle. Learn more about the award and previous recipients. Contact: AMS Communications. ***** The American Mathematical Society is dedicated to advancing research and connecting the diverse global mathematical community through our publications, meetings and conferences, MathSciNet, professional services, advocacy, and awareness programs. Full Article
ath US Navy destroyers unscathed after fighting off a complex attack of cruise and ballistic missiles and exploding drones By www.yahoo.com Published On :: 2024-11-12T21:02:14Z Full Article
ath She heard knocking beneath the floor of her home for weeks. Police make a disturbing discovery By www.yahoo.com Published On :: 2024-11-12T01:48:09Z Full Article
ath Near-death experience inspires Benzly Hype’s album By jamaica-star.com Published On :: Tue, 12 Nov 2024 05:01:17 -0500 An out-of-body experience is the inspiration behind Benzly Hype's latest album Star Its The 7th Year. Released on November 7, the entertainer said the project was done to bring back joy in music and will leave its listeners in an upbeat mood.... Full Article
ath Genetic diseases of the Kennedy pathways for membrane synthesis [Molecular Bases of Disease] By www.jbc.org Published On :: 2020-12-18T00:06:18-08:00 The two branches of the Kennedy pathways (CDP-choline and CDP-ethanolamine) are the predominant pathways responsible for the synthesis of the most abundant phospholipids, phosphatidylcholine and phosphatidylethanolamine, respectively, in mammalian membranes. Recently, hereditary diseases associated with single gene mutations in the Kennedy pathways have been identified. Interestingly, genetic diseases within the same pathway vary greatly, ranging from muscular dystrophy to spastic paraplegia to a childhood blinding disorder to bone deformations. Indeed, different point mutations in the same gene (PCYT1; CCTα) result in at least three distinct diseases. In this review, we will summarize and review the genetic diseases associated with mutations in genes of the Kennedy pathway for phospholipid synthesis. These single-gene disorders provide insight, indeed direct genotype-phenotype relationships, into the biological functions of specific enzymes of the Kennedy pathway. We discuss potential mechanisms of how mutations within the same pathway can cause disparate disease. Full Article
ath Workers at the Secrets and Breathless resorts protest overwork and low wages By jamaica-star.com Published On :: Tue, 12 Nov 2024 12:55:26 -0500 Staff at the Secrets and Breathless resorts in Montego Bay, St James, walked off the job this morning complaining of overwork, low wages, lack of overtime pay and disrespect. Full Article
ath Father imprisoned for sexually molesting daughter By jamaica-star.com Published On :: Tue, 12 Nov 2024 14:54:04 -0500 A father who pleaded guilty to sexually molesting his 13-year-old daughter was sentenced to several years of imprisonment in the St Catherine Circuit Court on Tuesday. Full Article