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Statin therapy is associated with lower prevalence of gut microbiota dysbiosis




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Statin drugs might boost healthy gut microbes




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First CRISPR test for the coronavirus approved in the United States




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Breaking through the glioblastoma micro-environment via extracellular vesicles




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The nuclear oncoprotein Fra-1: a transcription factor knocking on therapeutic applications’ door




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Effects of chronic type 5 phosphodiesterase inhibition on penile microvascular reactivity in hypertensive patients with erectile dysfunction: a randomized crossover placebo-controlled trial




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Mechanisms by which angiotensin-receptor blockers increase ACE2 levels




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A metabolic labeling method detects m<sup>6</sup>A transcriptome-wide at single base resolution




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Asymmetry across the membrane




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TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome




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Author Correction: A structural model for microtubule minus-end recognition and protection by CAMSAP proteins




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CDK11 is required for transcription of replication-dependent histone genes




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Real-time observation of CRISPR spacer acquisition by Cas1–Cas2 integrase




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Publisher Correction: High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble




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Electrolytes for microsized silicon




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Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons




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Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals




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Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation




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Structure of severe fever with thrombocytopenia syndrome virus L protein elucidates the mechanisms of viral transcription initiation




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Nature Microbiology




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A Buddhism Critic Goes on a Silent Buddhist Retreat

Something weird happens to a skeptical science writer during a week of meditation, chanting and skygazing




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Global Warming Linked to Higher Suicide Rates across North America

A 1 degree Celsius rise corresponded to a 1.4 percent increase in suicides




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High-level Postdoctoral research fellow recruitment - The international Joint Center for Biomedical Innovation (JCBI), Henan University : Kaifeng, China

The international Joint Center for Biomedical Innovation (JCBI) is comprised of two partner research nodes using nanoparticle technologies to develop solutions for cancer and neurodegenerative diseases diagnostics. Henan University has established a new research laboratory in nano-bio system innovation and theranostics, with start-up funding and new academic positions. Macquarie’s node is built upon its established excellence in neuroscience and cancer research programs. The collaborative succes…




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Talents Recruitment by Shandong First Medical University (Shandong Academy of Medical Sciences)

Shandong First Medical University (Shandong Academy of Medical Sciences) has been actively promoting the strategy of “invigorating the university through talents” and therefore has formulated a series of high-level talent introduction programs, and welcome talents at home and abroad to join us.

1. Qualifications for Different Levels of Applicants:

(1) Strategic Talents

This level targets academicians or experts with the qualifications that the applicants should be no more than 65 …




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Recruitment of Faculty for Peking University International Cancer Institute (PKUICI)

About Peking University International Cancer Institute (PKUICI)
Peking University International Cancer Institute(PKUICI) was formally established in 2019. With the support of School of Basic Medical Sciences, Cancer Hospital, People's Hospital, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, School of Pharmaceutical Sciences, School of Public Health, College of Engineering and other affiliated hospitals of Peking University, PKUICI is aimed to attract and create wor…




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Recruitment for director and research principal investigators of Shanghai Key Laboratory of Tissue Engineering Research, at Shanghai Ninth People's Hospital, Shanghai Jiao Tong University

Position
Laboratory director and independent principal investigators

Employer
Shanghai Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine

Location
639 Zhi Zao Ju Rd, Huang Pu District, 200011, Shanghai, China

Discipline
Tissue engineering and regenerative medicine related disciplines including: Stem Cell, Developmental Biology, Biomaterials, Biomedical Engineering

Aim:
Shanghai Tissue Engineering Key Laboratory is among the l…




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Molecular profiling of stroma highlights stratifin as a novel biomarker of poor prognosis in pancreatic ductal adenocarcinoma




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Author Correction: Genetic circuit design automation for the gut resident species <i>Bacteroides thetaiotaomicron</i>




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The expression of YAP1 is increased in high-grade prostatic adenocarcinoma but is reduced in neuroendocrine prostate cancer




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Effect of simulated microgravity on the antidiabetic properties of wheatgrass (<i>Triticum aestivum</i>) in streptozotocin-induced diabetic rats

npj Microgravity, Published online: 24 February 2020; doi:10.1038/s41526-020-0096-x

Effect of simulated microgravity on the antidiabetic properties of wheatgrass (Triticum aestivum) in streptozotocin-induced diabetic rats




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Growth of microorganisms in an interfacially driven space bioreactor analog

npj Microgravity, Published online: 08 April 2020; doi:10.1038/s41526-020-0101-4

Growth of microorganisms in an interfacially driven space bioreactor analog




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CRISPR off-target detection with DISCOVER-seq




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Author Correction: Guidance for quantitative confocal microscopy




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Simultaneous quantification of protein–DNA interactions and transcriptomes in single cells with scDam&amp;T-seq




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Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy




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CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians




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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




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WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2




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LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression




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NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas




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MicroRNA let-7c (MIRLET7C; let-7c), miR-99a and miR-125b as prognostic markers of luminal breast cancer

Studies in patient samples and cell culture suggest let-7c, miR-99a and miR-125b could serve as prognostic markers in patients with estrogen receptor–positive luminal breast cancers.




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




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Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs

miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors.




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HIV reverse transcriptase

In vitro studies have identified indolylarylsulfone derivatives that could help treat HIV infection.




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LIS1 cracks open dynein




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Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling




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Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis




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FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome




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Transcription factors in ferroptotic cell death




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MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis