cid Mutant cells in the esophagus, and protecting farmers from dangerous pesticide exposure By traffic.omny.fm Published On :: Thu, 18 Oct 2018 15:15:00 -0400 As you age, your cells divide over and over again, leading to minute changes in their genomes. New research reveals that in the lining of the esophagus, mutant cells run rampant, fighting for dominance over normal cells. But they do this without causing any detectable damage or cancer. Host Sarah Crespi talks to Phil Jones, a professor of cancer development at the University of Cambridge in the United Kingdom, about what these genome changes can tell us about aging and cancer, and how some of the mutations might be good for you. Most Western farmers apply their pesticides using drones and machinery, but in less developed countries, organophosphate pesticides are applied by hand, resulting in myriad health issues from direct exposure to these neurotoxic chemicals. Host Meagan Cantwell speaks with Praveen Vemula, a research investigator at the Institute for Stem Cell Biology and Regenerative Medicine in Bengaluru, India, about his latest solution—a cost-effective gel that can be applied to the skin to limit pesticide-related toxicity and mortality. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image:Navid Folpour/Flickr; Music: Jeffrey Cook] Full Article Scientific Community
cid Promising approaches in suicide prevention, and how to retreat from climate change By traffic.omny.fm Published On :: Thu, 22 Aug 2019 14:00:00 -0400 Changing the National Suicide Prevention Lifeline from 1-800-273- 8255 (TALK) to a three-digit number could save lives—especially when coupled with other strategies. Host Meagan Cantwell talks to Greg Miller, a science journalist based in Portland, Oregon, about three effective methods to prevent suicides—crisis hotlines, standardizing mental health care, and restricting lethal means. Greg’s feature is part of a larger package in Science exploring paths out of darkness. With more solutions this week, host Sarah Crespi speaks with A. R. Siders, a social scientist at the Disaster Research Center at the University of Delaware in Newark, about her policy forum on the need for “managed climate retreat”—strategically moving people and property away from high-risk flood and fire zones. Integrating relocation into a larger strategy could maximize its benefits, supporting equality and economic development along the way. This week’s episode was edited by Podigy. Ads on this show: KiwiCo; Kroger Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Scott Woods-Fehr/Flickr; Music: Jeffrey Cook] Full Article Scientific Community
cid Squeezing two people into an MRI machine, and deciding between what’s reasonable and what’s rational By traffic.omny.fm Published On :: Thu, 09 Jan 2020 14:00:00 -0500 Getting into an MRI machine can be a tight fit for just one person. Now, researchers interested in studying face-to-face interactions are attempting to squeeze a whole other person into the same tube, while taking functional MRI (fMRI) measurements. Staff Writer Kelly Servick joins host Sarah Crespi to talk about the kinds of questions simultaneous fMRIs might answer. Also this week, Sarah talks with Igor Grossman, director of the Wisdom and Culture Lab at the University of Waterloo, about his group’s Science Advances paper on public perceptions of the difference between something being rational and something being reasonable. This week’s episode was edited by Podigy. Read a transcript (PDF) Listen to previous podcasts. About the Science Podcast Full Article Scientific Community
cid Ultra-trace determination of domoic acid in the Ebro Delta estuary by SPE-HILIC-HRMS By feeds.rsc.org Published On :: Anal. Methods, 2020, 12,1966-1974DOI: 10.1039/C9AY02617G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Cristina Bosch-Orea, Josep Sanchís, Damiá Barceló, Marinella FarréMarine phytoplankton, such as diatoms, are responsible for a considerable part of carbon fixation and form the basis of the marine food web.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Analysis of amino acid enantiomers from aged fingerprints By feeds.rsc.org Published On :: Anal. Methods, 2020, 12,2052-2057DOI: 10.1039/D0AY00096E, Technical Note Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ward van Helmond, Maarten Weening, Vonne Vleer, Marcel de PuitThe use of the enantiomeric ratio of D/L-serine in fingerprints could pose as interesting target for age estimation techniques.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Evaluation of segmented non-target data acquisition (SWATH/vDIA) in a QToF and QOrbitrap for pesticide residue analysis By feeds.rsc.org Published On :: Anal. Methods, 2020, 12,2027-2038DOI: 10.1039/D0AY00290A, PaperŁukasz Rajski, Iciar Beraza, María José Gómez Ramos, Carmen Ferrer, Amadeo R. Fernández-AlbaTwo high-resolution instruments (a QToF and a QOrbitrap) were used to evaluate a segmented non-target MS2 (SWATH/vDIA) acquisition for pesticide residue analysis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Liquid–liquid microextraction of glyphosate, glufosinate and aminomethylphosphonic acid for the analysis of agricultural samples by liquid chromatography By feeds.rsc.org Published On :: Anal. Methods, 2020, 12,2039-2045DOI: 10.1039/D0AY00120A, PaperJavier Marín, Natalia Campillo, Manuel Hernández-Córdoba, Isabel Garrido, José Fenoll, Pilar ViñasAn ion-pair liquid–liquid microextraction procedure followed by LC tandem mass spectrometry allows a reliable and sensitive determination glyphosate, glufosinate y aminomethylphosphonic acid in agricultural samples.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Detection of prostate-specific antigen in semen using DNA aptamers: an application of nucleic acid aptamers in forensic body fluid identification By feeds.rsc.org Published On :: Anal. Methods, 2020, Accepted ManuscriptDOI: 10.1039/D0AY00371A, PaperTetsuya Satoh, Seiya Kouroki, Yusuke Kitamura, Toshihiro Ihara, Kazutoshi Matsumura, Susumu IwaseIn forensics, body fluid identification plays an important role because it aids in reconstructing the crime scene. Therefore, it is essential to develop simple and reliable techniques for body fluid...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Targeted profiling of amino acid metabolome in serum by a liquid chromatography-mass spectrometry method: application to identify potential markers for diet-induced hyperlipidemia By feeds.rsc.org Published On :: Anal. Methods, 2020, Advance ArticleDOI: 10.1039/D0AY00305K, PaperXiao-fan Wang, You-xi Zhang, Hai-ying MaTargeted profiling of amino acid metabolome in serum by LC-MS: application to identify potential markers for diet-induced hyperlipidemia.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Determination of polychlorinated biphenyls and organochlorine pesticides in Chinese mitten crabs (Eriocheir sinensis) using modified QuEChERS followed by GC-MS By feeds.rsc.org Published On :: Anal. Methods, 2020, Advance ArticleDOI: 10.1039/D0AY00519C, PaperTing Liu, Jianguang Zhou, Li He, Jinhua GanA new QuEChERS method followed by GC-MS was developed for the simultaneous analysis of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) in Chinese mitten crabs.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Colorimetric speciation analysis of chromium using 2-thiobarbituric acid capped silver nanoparticles By feeds.rsc.org Published On :: Anal. Methods, 2020, Advance ArticleDOI: 10.1039/D0AY00160K, PaperKamal Mousapour, Salahaddin Hajizadeh, Khalil FarhadiColorimetric determination of Cr(III) and Cr(VI) based on 2-thiobarbituric acid capped silver nanoparticles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Colorimetric indicators for volatile amines based on succinic anhydride (SAh)-grafted poly (lactic acid) (PLA) By feeds.rsc.org Published On :: Anal. Methods, 2020, Advance ArticleDOI: 10.1039/D0AY00550A, PaperAdrian Lopera-Valle, Anastasia EliasSmart materials that can undergo changes in color upon the detection of amines have the potential to provide information on the freshness of fish and meat.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Facile dispersive solid-phase extraction based on humic acid for the determination of aflatoxins in various edible oils By feeds.rsc.org Published On :: Anal. Methods, 2020, Advance ArticleDOI: 10.1039/D0AY00534G, PaperPing Liu, Yan-Hua Liao, Hao-Bo Zheng, Yang TangAflatoxins (AFs), as the secondary metabolites produced by some toxigenic fungi of Aspergillus species, are well known to be extremely harmful to humans and animals because of their high toxicity, mutagenicity, carcinogenicity, and teratogenicity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Miniaturized QuEChERS method for determination of 97 pesticide residues in wine by ultra-high performance liquid chromatography coupled to tandem mass spectrometry By feeds.rsc.org Published On :: Anal. Methods, 2020, Accepted ManuscriptDOI: 10.1039/D0AY00744G, PaperGabrieli Bernardi, Magali Kemmerich, Martha B Adaime, Osmar Damian Prestes, Renato ZanellaA miniaturized sample preparation method was developed and validated for the multiresidue determination of 97 pesticide residues in wine samples. The proposed extraction procedure is based on QuEChERS acetate method...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid LC-MS in combination with DMBA derivatization for sialic acid speciation and distribution analysis in fish tissues By feeds.rsc.org Published On :: Anal. Methods, 2020, 12,2221-2227DOI: 10.1039/D0AY00100G, PaperJunjie Du, Qiwei Zhang, Jianjun Li, Qi ZhengFor sialic acid speciation analysis, DMBA provides superior chromatographic separation efficiency and comparable MS/MS spectra with DMB.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid A simple paper-based approach for arsenic determination in water using hydride generation coupled with mercaptosuccinic-acid capped CdTe quantum dots By feeds.rsc.org Published On :: Anal. Methods, 2020, Accepted ManuscriptDOI: 10.1039/D0AY00273A, PaperOraphan Thepmanee, Kanlaya Prapainop Katewongsa, Obnithi Nooppha, Nuanlaor Ratanawimarnwong, Weena Siangproh, Orawon Chailapakul, Kriangsak SongsriroteThis research aims to develop a simple paper-based device for arsenic detection in water samples where a hydride generation technique coupled with mercaptosuccinic acid-capped CdTe quantum dots (MSA-CdTe QDs) as...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Rapid and colorimetric detection of nucleic acids based on entropy-driven circuit and DNAzyme mediated autocatalytic reaction By feeds.rsc.org Published On :: Anal. Methods, 2020, Accepted ManuscriptDOI: 10.1039/D0AY00341G, PaperHongli Shi, Jianyuan Dai, fang Wang, Yushun Xia, Dan Xiao, Cuisong ZhouIn this work, a novel, rapid and enzyme-free colorimetric biosensor for nucleic acids detection has been developed based on entropy-driven circuit (EDC) and DNAzyme mediated autocatalytic reaction. Upon sensing of...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Sharing mobilities: questioning our right to the city in the collaborative economy / Davide Arcidiacono and Mike Duggan By library.mit.edu Published On :: Sun, 8 Mar 2020 06:23:59 EDT Rotch Library - HE305.A735 2020 Full Article
cid Back on track: American railroad accidents and safety, 1965-2015 / Mark Aldrich By library.mit.edu Published On :: Sun, 26 Apr 2020 06:32:35 EDT Hayden Library - HE1780.A75 2018 Full Article
cid Demographic determinants of testing incidence and COVID-19 infections in New York City neighborhoods [electronic resource] / George J. Borjas By darius.uleth.ca Published On :: Cambridge, Mass. : National Bureau of Economic Research, 2020 Full Article
cid The army and the Indonesian genocide [electronic resource] : mechanics of mass murder / Jess Melvin By prospero.murdoch.edu.au Published On :: Melvin, Jess, author Full Article
cid [ASAP] Sulfenic Acid-Mediated on-Site-Specific Immobilization of Mitochondrial-Targeted NIR Fluorescent Probe for Prolonged Tumor Imaging By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Analytical ChemistryDOI: 10.1021/acs.analchem.9b05855 Full Article
cid [ASAP] Metal–Organic Framework-Enhanced Solid-Phase Microextraction Mass Spectrometry for the Direct and Rapid Detection of Perfluorooctanoic Acid in Environmental Water Samples By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Analytical ChemistryDOI: 10.1021/acs.analchem.9b05524 Full Article
cid Aurangabad train accident: NHRC issues notice to Maharashtra, says tragedy could have been averted By feedproxy.google.com Published On :: Fri, 08 May 2020 15:35:38 +0000 Meanwhile, the railway safety watchdog said the victims had gathered along the track under the impression that the train services have been suspended. Full Article
cid Aurangabad train accident: MP government’s negligence led to deaths of 16 migrants, alleges Congress By feedproxy.google.com Published On :: Sat, 09 May 2020 10:41:46 +0000 The party said that the workers had applied to the state government for passes to return home, but the administration did not act on it. Full Article
cid [ASAP] Reactivity Parameters and Substitution Effect in Organic Acids By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT The Journal of Physical Chemistry ADOI: 10.1021/acs.jpca.9b10258 Full Article
cid [ASAP] Proton Transfer in Phosphoric Acid-Based Protic Ionic Liquids: Effects of the Base By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT The Journal of Physical Chemistry ADOI: 10.1021/acs.jpca.0c02863 Full Article
cid Developing Super Tough Gelatin-based Hydrogels by Incorporating Linear Poly(methacrylic Acid) to Facilitate Sacrificial Hydrogen Bonding By feeds.rsc.org Published On :: Soft Matter, 2020, Accepted ManuscriptDOI: 10.1039/D0SM00422G, CommunicationHui Jie Zhang, Li Ni Wang, Xuechuan Wang, Qingxin Han, Xiangyou YouMechanically robust protein-based hydrogels are strongly desired but their construction remains a significant challenge. In this work, gelatin, together with methacrylic acid, is used to construct a novel hydrogen-bonded hydrogel...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid Effect of polar amino acid incorporation on Fmoc-diphenylalanine-based tetrapeptides By feeds.rsc.org Published On :: Soft Matter, 2020, Accepted ManuscriptDOI: 10.1039/D0SM00320D, PaperAlexandra Daryl Ariawan, Biyun Sun, Jonathan Pawel Wojciechowski, Ian Lin, Eric Y Du, Sophia C Goodchild, Charles Gordon Cranfield, Lars M Ittner, Pall Thordarson, Adam David MartinPeptide hydrogels show great promise as extracellular matrix mimics due to their tuneable, fibrous nature. Through incorporation of polar cationic, polar anionic or polar neutral amino acids into the Fmoc-diphenylalanine...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cid The Accidental Side Project By feedproxy.google.com Published On :: Tue, 24 Dec 2019 12:00:00 +0000 Drew McLellan puts the chairs up on the tables, sweeps the floor, and closes off our season, and indeed the entire 24 ways project with a look back at what it’s meant to run this site as a site project, and what impact side projects can have on the work we do. Will the last one out turn off Christmas the lights? Brought to you by The CSS Layout Workshop. Does developing layouts with CSS seem like hard work? How much time could you save without all the trial and error? Are you ready to really learn CSS layout? Fifteen years ago, on a bit of a whim, I decided it would be fun to have a Web Standards version of something like the Perl Advent calendar. A simple website with a new tip or trick each day leading the readers through December up until Christmas. I emailed a bunch of friends that kept web design and development themed blogs (remember those?) suggesting the idea and asking if they’d like to contribute. My vision had been that each post would be a couple of paragraphs of information. A small nugget of an idea, or a tip, or a suggestion. What happened was something really amazing. I began to receive really insightful blog posts containing some of the most valuable writing I’d seen online all year. Look at this piece from Ethan Marcotte on Centered Tabs with CSS, or this detailed piece on scripting block quotes from Jeremy Keith. I was blown away, and the scene was set. Part of the original design. Photo by Bert Heymans. Collaboration What I hadn’t anticipated in 2005 was that this little side project would turn into a fixture of the industry calendar, would introduce me to a raft of field experts, and would have me working with an eclectic team of collaborators for fifteen long seasons. And that last point is crucial. I’ve by no means produced this alone. Rachel Andrew has been a constant supporter in helping each year to see the light of day and producing our ebooks. After a couple of years, Brian Suda stepped in to help me plan and select authors. In 2008, I managed to persuade Tim Van Damme to replace my very basic site design with something altogether more fitting. In 2010, Anna Debenham came on board initially to help with the production of articles, but rapidly became a co-producer working with me on all aspects of the content. Owen Gregory joined up that same year to help with the proofing and editing of articles, and for many years did a fantastic job writing the home page article teasers, which are now but a shadow of their former selves. Tim Van Damme’s 2008 redesign. Also in 2010, we produced a book in collaboration with Five Simple Steps and raising funds in the memory of Remy and Julie’s daughter, Tia Sharp. The Five Simple Steps 24 ways book. Photo by Patrick Haney. In 2013, Paul Robert Lloyd stepped up to the plate to provide us with the design you see today, which not only subtly shifts colours between each day, but across the years as well. Compare the reds of 2005 to the purples of 2019, and the warm tones of a Day 1 to its correspondingly cool Day 24. It’s a terrific piece of work. Paul Robert Lloyd’s design plays subtly with colour shifts. In 2014 we won a Net Award for Best Collaborative Project at a fancy ceremony in London. Many past authors were there, and as it was an aware for our collaborative efforts, we all posed with the glassware for photos. We all went to a right fancy do. Looking back, looking forward But even I, Sea Captain Belly Button am not enough of a navel gazer to just be writing an article just about this website. As we draw our fifteenth and final year to a close, it’s important to reflect on what can be learned. Not from the articles (so much!) or from the folly of committing to a nightly publishing schedule for a month every year for fifteen years (don’t do it!) but from the value in starting something not because you have to, but just because you want to. From scratching an itch. From working with a friend just because you love spending time with them. Or for doing something because you see the opportunity for good. As web designers and developers, we have the opportunity to turn the skills we use in our profession to so many different purposes. In doing so you never know what good might come from it. Seeing the good This week I asked around to find out what good others have seen from their side projects. Long time 24 ways contributor Simon Willison had this to say: Basically every job I’ve ever had relates back to a side-project in some way— Simon Willison (@simonw) December 17, 2019 Simon went onto explain how it was a website side project that got him his first job in tech. After that, his personal blog lead him to getting a job at Lawrence Journal-World where he created Django. On his honeymoon, Simon and his new wife (and 24 ways contributor) Natalie Downe created Lanyrd, and Simon’s more recent Datasette project landed him a JSK Fellowship at Stanford. That’s an impressive record of side projects, for sure. Others had similar stories. My good friend Meri Williams is currently CTO of challenger bank Monzo, as well as being a trustee at Stonewall and Chair of The Lead Developer conference. I got asked to write the book you tech reviewed off the back of a Meetup talk. Chairing @TheLeadDev has led to me getting to hire & work with so many new brilliant people, as well as getting me multiple CTO gigs (both perm & interim) Got the gig chairing Lead Dev after meeting @RuthYarnit at a dev meet-up in the basement of a pub in Reading (which I think @drewm you also spoke at / introduced me to!)Leading LGBTQ employee network at P&G eventually led to my applying for board role at Stonewall — Meri Williams ???????????? (@Geek_Manager) December 18, 2019 Again, an impressive list of achievements, and I’m sure both Simon and Meri would have eventally found other routes to their individual success, but the reality is they did it through side projects. Through being present and active, contributing a little to their communities, and receiving so much more back in return. Of course, not all projects have to be directly related to the web or software to be fulfilling. Of course they don’t. Mark Small and Jack Shoulder embraced their love of a good rear end and created MuseumBums, informally cataloging perfect posteriors for your perusing pleasure. On its success, Mark says: Ok! We’ve been profiled in the Cambridge Independent, the Sun and the Metro; raised money for Prostate Cancer UK; created a little community of museum fans who aren’t afraid to be a bit silly online; and we’ve got a list of big ideas for developing our ????????️???? offer further! ????— Marky Smallstice ???????????? (@thehistoryb0y) December 17, 2019 Jack adds: We’ve also got a shout out on @BBCRadio4 and helped a beloved museum achieve record numbers of visitors. Wow. It’s been a *year*— Jack Frost (@jackshoulder) December 17, 2019 I had so many heartwarming responses to my request for stories, I really recommend you go over to the thread on Twitter and read it. It’s been one of my favourite set of replies in a long time. Focussing on what’s important As the years progressed, more and more publications sprang up both at Christmas and throughout the year with how-to articles explaining techniques. As a natural response, 24 ways started mixing up solution-based articles with bigger picture takes on a wider range of topics, but always with a practical takeaway to impress your friends. After the embarrassment of white dudes that dominated the early years, we actively sought to open the opportunity to write to a wider and more diverse range of experts. While I don’t think we ever got as much racial diversity in our lineup as I would have liked to have achieved, I’m very proud that each season has been closely gender-balanced since 2012. This is something that was never forced or remotely hard to achieve, all it took was an awareness of the potential for bias. Calling time With all the benefits that side projects can bring, it’s also important to be mindful of downsides. Not every project will take flight, and those that do can also start to consume valuable time. That’s fine while it’s fun and you’re seeing the benefits, but it’s neither fun or healthy long-term to have no time away from something that might otherwise be your job. Spending time with family, friends, and loved ones is equally important especially at this time of year. Just as anyone who does a lot of sport or fitness will tell you about the value of rest days between your activities to let the body recover, time away from ‘work’ is important to do the same for your brain. Having run this site every Christmas for 15 seasons, it’s time to take a breather and give it a rest. Who knows if we might return in the future, but no promises. It’s been a good run, and an absolute privilege to provide this small tradition to the community I love. So from me and the whole 24 ways family, Happy Christmas to all, and to all a good night. Anna and Drew at the 2014 Net Awards dinner. About the author Drew McLellan is a developer and content management consultant from Bristol, England. He’s the lead developer for the popular Perch and Perch Runway content management systems, and public speaking portfolio site Notist. Drew was formerly Group Lead at the Web Standards Project, and a Search Innovation engineer at Yahoo!. When not publishing 24 ways, he keeps a personal site about web development, takes photos, tweets a lot and tries to stay upright on his bicycle. More articles by Drew Full Article Business business
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