Deer and other wildlife often cross our paths during the fall season. What should I keep in mind whi

Secaucus, NJ — Lyme disease is becoming more common outside the Northeast and more prevalent in the United States overall, a recent study by lab services provider Quest Diagnostics shows.

Adelaide, Australia — Open toilet lids, defective plumbing drains and uncovered trash cans may increase the risk of bacterial and viral disease transmission in public restrooms, according to a recent research review.

One serious risk of outdoor work is Lyme disease, which is spread when individuals are bitten by infected ticks. Initial symptoms of the disease include fever, headache, fatigue and skin rash.

Occupational skin diseases are the second-most common type of occupational disease. NIOSH estimates that more than 13 million U.S. workers are potentially exposed to chemicals that can be absorbed through their skin.

Washington — OSHA’s proposed rule on infectious diseases in “health care and other high-risk environments” has been submitted to the White House Office of Information and Regulatory Affairs for final review.

How does facility safety go beyond building infrastructure and protocol during hurricane season?

The use of flavored e-liquids in vaping devices may lead to the formation of nearly 300 different harmful substances, results of a recent study out of Ireland suggest.

Nanjing, China — A recent study highlighting the expected ties between exposure to cancer-causing per- and polyfluoroalkyl substances, or PFAS, and a risk factor for heart disease could impact workers.

Dallas — During inclement weather, facility operators are obligated to maintain safety, minimize any chemical/oil releases and discharges, and report them in a timely manner.

More than a dozen Seasoning Blends & Packets, BBQ Sauces, and Hot Sauce varieties will be available this month for online shipping and at select grocery stores nationwide, with greater national retail rollout in June.

 Knorr Liquid Seasoning Chili combines the classic Knorr Liquid Seasoning with a spicy kick crafted from chili peppers and soy sauce for a balanced, robust flavor profile. 

As the season shifts, consumer preferences evolve, creating a valuable opportunity for food and beverage product developers to tap into fall-themed flavors. Whether your target market prefers to savor the last hints of summer or eagerly anticipates fall, now is the time to introduce innovative, seasonal products that align with both consumer health trends and seasonal nostalgia.

Children's Geographies; 10/01/2021
(AN 152966703); ISSN: 14733285
Academic Search Premier

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The post Notice of Special Interest (NOSI): Analysis of Existing Linked Datasets to Understand the Relationship between Housing Program Participation and Risk for Chronic Diseases and Other Conditions (R01-Clinical Trial Not Allowed) was curated by information for practice.

Buskirk-Chumley Theater
Friday, November 29, 2024, 5 – 9pm

Join the BSO for a treasured tradition as we celebrate the holiday season with two concerts. Our 5pm early show is perfect for families with small children, and finishes just in time for you to watch the City’s Canopy of Lights. The second, slightly longer 8pm program will top off your evening with a festive mix of holiday music from around the world. With a new “elf” leading us as Music Director, you can expect a fresh treat or two!

More details at bloomingtonsymphony.com/cts2024

Doors open 30 minutes before each performance.

Presenter: Bloomington Symphony Orchestra
Contact: BCT Box Office, boxoffice@buskirkchumley.org
Cost: $16 - $29
Ticket Phone: 812-323-3020
Ticket Web Link: buskirkchumley.org…
Communities: Bloomington

Christmas came early as stars, filmmakers and fans gathered for the red carpet premiere of “The Best Christmas Pageant Ever” — a family-friendly film creators hope will earn a spot among the holiday classics. 

After a 2nd place finish in the MLS last season, the Columbus Crew SC are looking for a little revenge to start their 2016 campaign.

Ohio State has rolled through most of its Big Ten games in recent years, but has taken tough criticism for a weak non-conference schedule. That changes this year, as the Buckeyes head to Norman, Oklahoma in the season's third week to take on the University of Oklahoma, a team that made the four-team postseason playoff last year.

Ohio State Football beings its 2016 campaign Saturday at noon in Ohio Stadium. The Buckeyes take on Bowling Green in what should be an easy win for Ohio State. Thomas Bradley and Steve Brown break down the matchup, the season and the team with Eric Seger from ElevenWarriors.com .

The Columbus Blue Jackets start a new season Thursday night. The Jackets open the season at home inside Nationwide Arena against the Boston Bruins, and expectations are down following a 2015-2016 season that ended with the Jackets as one of the league's worst teams.

University of Coimbra Failure by immune cells worsens Alzheimer's disease, reveals study by the University of Coimbra A team from the Center for Neuroscience and Cell Biology (CNC), University of Coimbra (UC) in Portugal discovered how some cells of the immune system lose the ability to fight Alzheimer's disease. This new knowledge can help to find a definitive diagnosis. Ana Luísa Cardoso, the coordinator of the research group, explains that "We found that monocytes (the innate immune system cells) of Alzheimer's patients are unable to move when stimulated by substances produced in the brain, which may lead to reduction of cells that can be recruited to the nervous tissue and participate in fighting the disease."

According to the latest Canalys data, worldwide tablet shipments reached 33 million in Q3 2023, marking a 7% annual decline. But this represents an 8% sequential increase, reflecting a revival of the tablet market ahead of the crucial holiday season and the strong performance of new entrants in the space.

With the holiday season fast approaching, retail payroll teams around the world are bracing for the strain of seasonal hiring. The influx of workers means added payroll runs, and yet too few are turning to technology to ease the pressure.

The peak season is renowned for Christmas cheer, retail opportunity, in store shopping, bustling shopping centres and queues. Additionally, shoppers and restaurant clientele are busy. They detest queues. Their time is precious. They have places to go and people to see.

University of Wisconsin-Madison researchers targeting a group of hereditary neurodegenerative diseases have found success using a gene therapy treatment in an animal model. The approach, which uses CRISPR-Cas9 genome editing technology, offers a unique and promising strategy that could one day treat rare but debilitating motor neuron diseases in humans.

The Korea Research Institute of Standards and Science (KRISS) announced that they have developed an advanced disease diagnosis and treatment system based on nanomaterials.

The Korea Research Institute of Standards and Science (KRISS) announced that they have developed an advanced disease diagnosis and treatment system based on nanomaterials.

What will my grocery bill be this holiday season?

[Politics] :
Defense Minister Kim Yong-hyun on Monday reiterated that sending an observation team to Ukraine is necessary for protecting national interest. During a National Assembly National Defense Committee session, Minister Kim said sending an observation team differs from troop deployment. He explained that a ...

[more...]

[Sports] :
The Kia Tigers have won the regular-season title in the Korea Baseball Organization(KBO), heading straight to the Korean Series. The Tigers were defeated by the SSG Landers 2-0 Tuesday but secured the regular-season title as second-place Samsung Lions lost 8-4 to the Doosan Bears. With seven games ...

[more...]

[Sports] :
South Korean forward Son Heung-min of the Tottenham Hotspur has picked up his first two assists of the season, helping his club with the second win of the season. Son set up Brennan Johnson's 28th-minute goal in a match against Brentford on Saturday at Tottenham Hotspur Stadium in London, breaking ...

[more...]

[Science] :
The Animal and Plant Quarantine Agency says it has developed, for the first time in the world, a differential diagnosis technology for lumpy skin disease(LSD), a viral disease that affects cattle. With the technology, jointly developed with Median Diagnostics, it can be determined within eight hours if a ...

[more...]

[Science] :
Seoul, Daejeon and other inland areas experienced the first frost of the fall season Wednesday. In Seoul and Suwon, Gyeonggi Province, the first frost was observed two days earlier than last year and nine days later than average. Daejeon reported its first frost 16 days later than last year and nine ...

[more...]

Explore Aquarius Season's unique energy, from innovation to social connection. Learn how this zodiac period influences creativity, relationships, and self-expression.

Patrick Doherty volunteered for a new medical intervention of gene-editor infusions for the treatment of genetically-based diseases.; Credit: /Patrick Doherty

Patrick Doherty had always been very active. He trekked the Himalayas and hiked trails in Spain.

But about a year and a half ago, he noticed pins and needles in his fingers and toes. His feet got cold. And then he started getting out of breath any time he walked his dog up the hills of County Donegal in Ireland where he lives.

"I noticed on some of the larger hill climbs I was getting a bit breathless," says Doherty, 65. "So I realized something was wrong."

Doherty found out he had a rare, but devastating inherited disease — known as transthyretin amyloidosis — that had killed his father. A misshapen protein was building up in his body, destroying important tissues, such as nerves in his hands and feet and his heart.

Doherty had watched others get crippled and die difficult deaths from amyloidosis.

"It's terrible prognosis," Doherty says. "This is a condition that deteriorates very rapidly. It's just dreadful."

So Doherty was thrilled when he found out that doctors were testing a new way to try to treat amyloidosis. The approach used a revolutionary gene-editing technique called CRISPR, which allows scientists to make very precise changes in DNA.

"I thought: Fantastic. I jumped at the opportunity," Doherty says.

On Saturday, researchers reported the first data indicating that the experimental treatment worked, causing levels of the destructive protein to plummet in Doherty's body and the bodies of five other patients treated with the approach.

"I feel fantastic," Doherty says. "It's just phenomenal."

The advance is being hailed not just for amyloidosis patients but also as a proof-of-concept that CRISPR could be used to treat many other, much more common diseases. It's a new way of using the innovative technology.

"This is a major milestone for patients," says Jennifer Doudna of the University of California, Berkeley, who shared a Nobel Prize for her work helping develop CRISPR.

"While these are early data, they show us that we can overcome one of the biggest challenges with applying CRISPR clinically so far, which is being able to deliver it systemically and get it to the right place," Doudna says.

CRISPR has already been shown to help patients suffering from the devastating blood disorders sickle cell disease and beta thalassemia. And doctors are trying to use it to treat cancer and to restore vision to people blinded by a rare genetic disorder.

But those experiments involve taking cells out of the body, editing them in the lab, and infusing them back in or injecting CRISPR directly into cells that need fixing.

The study Doherty volunteered for is the first in which doctors are simply infusing the gene-editor directly into patients and letting it find its own way to the right gene in the right cells. In this case, it's cells in the liver making the destructive protein.

"This is the first example in which CRISPR-Cas9 is injected directly into the bloodstream — in other words systemic administration — where we use it as a way to reach a tissue that's far away from the site of injection and very specifically use it to edit disease-causing genes," says John Leonard, the CEO of Intellia Therapeutics, which is sponsoring the study.

Doctors infused billions of microscopic structures known as nanoparticles carrying genetic instructions for the CRISPR gene-editor into four patients in London and two in New Zealand. The nanoparticles were absorbed by their livers, where they unleashed armies of CRISPR gene-editors. The CRISPR editor honed in on the target gene in the liver and sliced it, disabling production of the destructive protein.

Within weeks, the levels of protein causing the disease plummeted. Researchers reported at the Peripheral Nerve Society Annual Meeting and in a paper published in The New England Journal of Medicine.

"It really is exciting," says Dr. Julian Gillmore, who is leading the study at the University College London, Royal Free Hospital.

"This has the potential to completely revolutionize the outcome for these patients who have lived with this disease in their family for many generations. It's decimated some families that I've been looking after. So this is amazing," Gillmore says.

The patients will have to be followed longer, and more patients will have to be treated, to make sure the treatment's safe, and determine how much it's helping, Gillmore stresses. But the approach could help those struck by amyloidosis that isn't inherited, which is a far more common version of the disease, he says.

Moreover, the promising results potentially open the door for using the same approach to treatment of many other, more common diseases for which taking cells out of the body or directly injecting CRISPR isn't realistic, including heart disease, muscular dystrophy and brain diseases such as Alzheimer's.

"This is really opening a new era as we think about gene-editing where we can begin to think about accessing all kinds of different tissue in the body via systemic administration," Leonard says.

Other scientists who are not involved in the research agree.

"This is a wonderful day for the future of gene-editing as a medicine,"
agree Fyodor Urnov, a professor of genetics at the University of California, Berkeley. "We as a species are watching this remarkable new show called: our gene-edited future."

Doherty says he started feeling better within weeks of the treatment and has continued to improve in the weeks since then.

"I definitely feel better," he told NPR. "I'm speaking to you from upstairs in our house. I climbed stairs to get up here. I would have been feeling breathless. I'm thrilled."

This content is from Southern California Public Radio. View the original story at SCPR.org.

Evidence exists linking three cancers and two other health problems with chemicals used in herbicides in the Vietnam War, a committee of the Institute of Medicine (IOM) has concluded.

A bold national initiative is needed to reduce the enormous health burden of sexually transmitted diseases (STDs) in the United States, according to a new report from a committee of the Institute of Medicine.

Insufficient evidence exists to support claims that taking megadoses of dietary antioxidants, such as selenium and vitamins C and E, or carotenoids, including beta-carotene, can prevent chronic diseases, says the latest report on Dietary Reference Intakes (DRIs) from the Institute of Medicine of the National Academies.

To meet the bodys daily energy and nutritional needs while minimizing risk for chronic disease, adults should get 45 percent to 65 percent of their calories from carbohydrates, 20 percent to 35 percent from fat, and 10 percent to 35 percent from protein.

The vast majority of healthy people adequately meet their daily hydration needs by letting thirst be their guide, says the newest report on nutrient recommendations from the Institute of Medicine of the National Academies.

A new report from the Institute of Medicine finds suggestive but limited evidence that exposure to Agent Orange and other herbicides used during the Vietnam War is associated with an increased chance of developing ischemic heart disease and Parkinsons disease for Vietnam veterans.

A new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of disease and ultimately enhance diagnosis and treatment, says a new report from the National Research Council.

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome -- commonly referred to as ME/CFS -- is a legitimate, serious, and complex systemic disease that frequently and dramatically limits the activities of affected individuals, says a new report from the Institute of Medicine.

Joint statements from the national science academies of the G7 nations were delivered today to the Italian government in advance of the G7 Summit to be held in Taormina, Italy, at the end of May.

A new report from the National Academies of Sciences, Engineering, and Medicine outlines how to examine whether specific levels of nutrients or other food substances (NOFSs) can ameliorate the risk of chronic disease and recommends ways to develop dietary reference intakes (DRI) based on chronic disease outcomes.

A single breakthrough discovery for managing citrus greening in Florida in the future is unlikely, says a new report by the National Academies of Sciences, Engineering, and Medicine.