palm

Des tumeurs synoviales de la partie infërieure de l'avant-bras, de la face palmaire du poignet, et de la main ... / par L.-M. Michon.

Londres : Paris, 1851.




palm

Diarrhoea and dysentery : modern views of their pathology and treatment / by Alonzo B. Palmer.

Detroit, Mich. : G.S. Davis, 1887.




palm

Palmyra, Syria: remains of the ancient buildings. Coloured etching, 17--.

[London] (No 69 St Paul's Churchyard) : Printed for Carington Bowles ; [London] (opposite Fetter Lane, Fleet Street) : Robt. Sayer ; [London] (in Cornhil) : Robert Wilkinson, [between 1700 and 1799]




palm

Palmyra, Syria: remains of the temple of the sun. Coloured etching, 17--.

[London] (in St Pauls Churchyard) : Printed for T. Bowles ; [London] (at the Black Horse in Cornhil) : John Bowles & Son ; [London] (opposite Fetter Lane in Fleet Street) : R. Sayer, [between 1700 and 1799]




palm

Mémoire sur l'empoisonnement par la strychnine : contenant la relation médico-légale complète de l'affaire Palmer / Ambroise Tardieu.

Paris, [France] : J.B. Baillière, Libraire de l'Académie Impériale de Médicine, 1857.




palm

How Napalm Bombs Intensified U.S. Attacks During WWII

Bombing ground targets from the air is tricky and not always accurate. But a new type of bomb creates an unimaginable level of destruction




palm

Carnitine Palmitoyltransferase I and Sudden Unexpected Infant Death in British Columbia First Nations

The CPT1A p.P479L variant is common to northern aboriginal populations, leads to reduced enzyme activity, and may be associated with increased infant mortality rates.

The p.P479L variant is common in British Columbia First Nations with a coastal distribution correlated with regions of high infant mortality. Homozygotes display an altered acylcarnitine profile and are overrepresented in cases of sudden unexpected infant death in these areas. (Read the full article)




palm

Penn State and Palmer Museum mourn death of donor and alumnus John Driscoll

Penn State and the Palmer Museum of Art mourn the loss of dear friend, generous donor, and loyal champion John P. Driscoll, who died from complications due to COVID-19 on Friday, April 10. Driscoll, owner of Driscoll Babcock Galleries in New York, was a longtime friend and supporter of the Palmer Museum and will be remembered for his role as a leader, gracious mentor and trusted adviser, as well as for the expansive gifts he made to the collection and to his alma mater, Penn State.




palm

Care is urged after imported fire ants found in palm tree shipment

State authorities are alerting local businesses and purchasers of tropical nursery stock of the recent detection of fire ants in a shipment of palm trees imported from Florida. The red imported fire ants were detected during a routine check at a Sussex County business by the Delaware Department of Agriculture's Plant Industries nursery inspection team. They were eradicated and do not pose a threat.




palm

Care is urged after red imported fire ants found in palm tree shipment

Red imported fire ants were detected during a routine check at a Sussex County business by the Delaware Department of Agriculture's Plant Industries nursery inspection team. A Hold and Control Order was promptly issued, and a treatment program to eliminate the fire ants is underway. "Buyers of tropical nursery stock - such as palm trees - should carefully inspect their plants for small, aggressive red stinging ants," said Stephen Hauss, Cooperative Agricultural Pest Survey Coordinator for the Department of Agriculture. "We need these to be reported quickly and promptly to keep them from spreading or staying in Delaware over the winter."



  • Department of Agriculture
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  • Delaware Department of Agriculture
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palm

As trade war looms, EU sets limits on Palm Oil in Biofuels

The biggest palm oil producers stepped up lobbying in Brussels to defend its future in the European market.




palm

PalmOShttpd.txt

A bug exists in the PalmOS httpd that causes a crash with a "Fatal Error". Full exploit included.




palm

LG International Expands Its Palm Oil Capacity in Indonesia

LG International will expand its palm oil operations in Indonesia for the first time in six years. This is a move for the trading company to focus more on the food resource business. The company recently broke the ground for the palm oil plant. It plans to complete the construction by the end of the first half of next year and start producing 110,000 tons of palm oil a year. This is an increase of 30,000 tons from the current capacity. Back in 2009, LG International jumped into the food re...




palm

Israeli missiles target fighters near Palmyra

Syrian state TV gave no further details about the attacks, the latest to hit central Syria in three weeks.




palm

Thousands of Amazon Shoppers Are Raving About This Palm-Sized Waterproof Speaker




palm

Extinct date palms grown from 2000-year-old seeds found near Jerusalem

An extinct variety of date palm tree has been grown from ancient seeds preserved in the Judean desert for 2000 years, the oldest seeds ever germinated




palm

Palmitoylated Cysteines in Chikungunya Virus nsP1 Are Critical for Targeting to Cholesterol-Rich Plasma Membrane Microdomains with Functional Consequences for Viral Genome Replication [Virus-Cell Interactions]

In mammalian cells, alphavirus replication complexes are anchored to the plasma membrane. This interaction with lipid bilayers is mediated through the viral methyl/guanylyltransferase nsP1 and reinforced by palmitoylation of cysteine residue(s) in the C-terminal region of this protein. Lipid content of membranes supporting nsP1 anchoring remains poorly studied. Here, we explore the membrane binding capacity of nsP1 with regard to cholesterol. Using the medically important chikungunya virus (CHIKV) as a model, we report that nsP1 cosegregates with cholesterol-rich detergent-resistant membrane microdomains (DRMs), also called lipid rafts. In search for the critical factor for cholesterol partitioning, we identify nsP1 palmitoylated cysteines as major players in this process. In cells infected with CHIKV or transfected with CHIKV trans-replicase plasmids, nsP1, together with the other nonstructural proteins, are detected in DRMs. While the functional importance of CHIKV nsP1 preference for cholesterol-rich membrane domains remains to be determined, we observed that U18666A- and imipramine-induced sequestration of cholesterol in late endosomes redirected nsP1 to these compartments and simultaneously dramatically decreased CHIKV genome replication. A parallel study of Sindbis virus (SINV) revealed that nsP1 from this divergent alphavirus displays a low affinity for cholesterol and only moderately segregates with DRMs. Behaviors of CHIKV and SINV with regard to cholesterol, therefore, match with the previously reported differences in the requirement for nsP1 palmitoylation, which is dispensable for SINV but strictly required for CHIKV replication. Altogether, this study highlights the functional importance of nsP1 segregation with DRMs and provides new insight into the functional role of nsP1 palmitoylated cysteines during alphavirus replication.

IMPORTANCE Functional alphavirus replication complexes are anchored to the host cell membranes through the interaction of nsP1 with the lipid bilayers. In this work, we investigate the importance of cholesterol for such an association. We show that nsP1 has affinity for cholesterol-rich membrane microdomains formed at the plasma membrane and identify conserved palmitoylated cysteine(s) in nsP1 as the key determinant for cholesterol affinity. We demonstrate that drug-induced cholesterol sequestration in late endosomes not only redirects nsP1 to this compartment but also dramatically decreases genome replication, suggesting the functional importance of nsP1 targeting to cholesterol-rich plasma membrane microdomains. Finally, we show evidence that nsP1 from chikungunya and Sindbis viruses displays different sensitivity to cholesterol sequestering agents that parallel with their difference in the requirement for nsP1 palmitoylation for replication. This research, therefore, gives new insight into the functional role of palmitoylated cysteines in nsP1 for the assembly of functional alphavirus replication complexes in their mammalian host.




palm

COMT-Catalyzed Palmitic Acid Methyl Ester Biosynthesis in Perivascular Adipose Tissue and its Potential Role Against Hypertension [Cardiovascular]

Decreased release of palmitic acid methyl ester (PAME), a vasodilator, from perivascular adipose tissue (PVAT) might contribute to hypertension pathogenesis. However, the PAME biosynthetic pathway remains unclear. In this study, we hypothesized that PAME is biosynthesized from palmitic acid (PA) via human catechol-O-methyltransferase (COMT) catalysis and that decreased PAME biosynthesis plays a role in hypertension pathogenesis. We compared PAME biosynthesis between age-matched normotensive Wistar Kyoto (WKY) rats and hypertensive spontaneously hypertensive rats (SHRs) and investigated the effects of losartan treatment on PAME biosynthesis. Computational molecular modeling indicated that PA binds well at the active site of COMT. Furthermore, in in vitro enzymatic assays in the presence of COMT and S-5'-adenosyl-L-methionine (AdoMet), the stable isotope [13C16]-PA was methylated to form [13C16]-PAME in incubation medium or the Krebs–Henseleit solution containing 3T3-L1 adipocytes or rat PVAT. The adipocytes and PVATs expressed membrane-bound (MB)-COMT and soluble (S)-COMT proteins. [13C16]-PA methylation to form [13C16]-PAME in 3T3-L1 adipocytes and rat PVAT was blocked by various COMT inhibitors, such as S-(5'-adenosyl)-L-homocysteine, adenosine-2',3'-dialdehyde, and tolcapone. MB- and S-COMT levels in PVATs of established SHRs were significantly lower than those in PVATs of age-matched normotensive WKY rats, with decreased [13C16]-PA methylation to form [13C16]-PAME. This decrease was reversed by losartan, an angiotensin II (Ang II) type 1 receptor antagonist. Therefore, PAME biosynthesis in rat PVAT is dependent on AdoMet, catalyzed by COMT, and decreased in SHRs, further supporting the role of PVAT/PAME in hypertension pathogenesis. Moreover, the antihypertensive effect of losartan might be due partly to its increased PAME biosynthesis.

SIGNIFICANCE STATEMENT

PAME is a key PVAT-derived relaxing factor. We for the first time demonstrate that PAME is synthesized through PA methylation via the S-5'-adenosyl-L-methionine–dependent COMT catalyzation pathway. Moreover, we confirmed PVAT dysfunction in the hypertensive state. COMT-dependent PAME biosynthesis is involved in Ang II receptor type 1–mediated blood pressure regulation, as evidenced by the reversal of decreased PAME biosynthesis in PVAT by losartan in hypertensive rats. This finding might help in developing novel therapeutic or preventive strategies against hypertension.




palm

Palm Heights 3 bedroom apartment No. 7 Tower T3 for sale

Palm Heights apartment for sale, T3-xx.07, with an area of 121m2, including 3 bedrooms, 2 bathrooms, double living room. Price: VND 5.8 Billion Palm Heights South Rach Chiec apartment is located at Song Hanh highway, Long Thanh Dau Giay with full of high-class facilities: Water ...




palm

Palm Residence villa/townhouse for rent, 3 bedrooms, 2 floors, interior

Palm Residence villa/townhouse for rent, 3 bedrooms, beautifully arranged with luxurious design, and fully furnished with high-quality furniture, details: - Construction area 6x17m - Building 1 ground floor + 2 floors, each floor has a large state. - Including 3 bedrooms, 1 livin...




palm

Villa in Palm Residence - 3 floors, 3 bedrooms with a camera and smart house system

The townhouse for rent in Palm Residence District 2 consists of 1 ground floor 2 floors, with total land area of 102m2 (6mx17m), usable area of 210m2. The extremely luxurious design includes 3 large bedrooms, 3 bathrooms, living room, dining room, 1 church room, 1 living room and...




palm

Video Friday: DJI's Mavic Mini Is a $400 Palm-Sized Foldable Drone

Your weekly selection of awesome robot videos




palm

John Lennon and Yoko Ono's former Palm Beach estate listed for $47.5 Million

Couple bought the property months before the former Beatle's 1980 assassination.




palm

Met Police faces legal action over PC Keith Palmer's murder in Westminster terror attack

The Met Police is facing legal action in regards to the murder of PC Keith Palmer in the Westminster terror attack.





palm

Outstanding Stays: Can Bordoy, Palma

We could all do with a strong dose of escapism right now, so each week we'll be highlighting a banging boutique to bookmark for when the world presses play again




palm

Some of the children that feature on the mural at Palm Beach.



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palm

Season Interrupted: Palm Desert's Jasmine Perezchica can take the heat

Reigning league MVP Jasmine Perezchica will go from one desert to another to chase her college dream: 'I really live and breathe softball.'




palm

Department of Justice Announces Palmetto Project to Expand Training and Operations at the National Advocacy Center

Deputy Attorney General David W. Ogden today announced plans by the Department of Justice to significantly expand its training and education operations at the National Advocacy Center (NAC), the core training facility for local, state and federal attorneys, law enforcement agents and support personnel.



  • OPA Press Releases

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Deputy Attorney General David W. Ogden at the Palmetto Project Press Event National Advocacy Center

"The Palmetto Project – as it is known – will allow the Department of Justice to expand the capabilities of the National Advocacy Center. As the core training center for prosecutors, law enforcement agents and other personnel from across the nation, the NAC is crucial to the continued success of the Justice Department’s mission."




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Attorney General Eric Holder at the Forum Club of the Palm Beaches

"We cannot ignore the fact that protecting our economy is an essential component of our larger security goals," said Attorney General Holder.




palm

West Palm Beach, Florida, Resident Charged in Multi-Million Dollar Cramming Scheme

Willoughby Farr, 46, of West Palm Beach, Fla., has been charged with perpetrating what is known as a cramming scheme, which was designed to place charges on consumers’ telephone bills for collect calls that were not made, the Justice Department and the U.S. Postal Inspector’s Miami Field Office announced today.



  • OPA Press Releases

palm

Former Guatemalan Special Forces Soldier Arrested in Palm Beach County, Fla., for Masking Role in 1982 Massacre of Guatemalan Villagers on Immigration Forms

A former Guatemalan special forces soldier was arrested today in Palm Beach County, Fla., for lying on his naturalization application about his participation in a 1982 massacre at a Guatemalan village known as Dos Erres.



  • OPA Press Releases

palm

Justice Department Reaches Settlement with School District of Palm Beach County, Fla., to Prevent and Address Discrimination in School Enrollment and Student Discipline

The Justice Department announced that it has reached a comprehensive settlement agreement with the School District of Palm Beach County, Fla., the nation’s eleventh-largest school district, to prevent and address discrimination in school enrollment and student discipline.



  • OPA Press Releases

palm

Welcome to Hondupalma, the world’s first sustainable certified palm oil cooperative!

Several years ago, this established cooperative in Honduras decided to pursue Rainforest Alliance certification for its palm oil. Find out what it looks like today.




palm

A palm oil farmer speaks about the industry in Honduras

Ramón Cruz has been growing oil palms for 37 years. He is a supporter of Rainforest Alliance's sustainable certification process.




palm

This is how palm oil is made

Palm oil is found in nearly everything, yet have you ever wondered who makes it? how it's processed? what palm fruit looks like? Take a tour through a Honduran palm oil plantation to learn more.




palm

17 product groups that contain palm oil

From cookies and cake mix to hair care and toothpaste, here's where to look for sneaky, eco-catastrophic palm oil.




palm

Winner of the Goldman Environmental Prize tackles illegal palm oil companies in Indonesia

From palm oil invaders to adorable Sumatran rhinos, this story about a recent environmental victory will inspire you.




palm

Palm Oil Biodiesel, Now With 2000% the Emissions of Fossil Fuels

Can we just all put palm oil biodiesel produced on deforested peatlands to rest already: A new report from the United Nations Environment Programme shows that biodiesel production under these




palm

Is boycotting palm oil really the best thing to do?

The palm oil situation is bad, but some people argue that it would be worse if replaced by other vegetable oils.




palm

What does Rainforest Alliance certification mean for palm oil?

We all know the palm oil industry has a horrible reputation for deforestation. The Rainforest Alliance, however, believes that change can happen from within and that sustainable palm oil production is attainable.




palm

We Breathe What We Buy: How palm oil is driving air pollution in Asia

The fires used to clear land for new palm oil plantations are out of control this year, and much of Asia is cloaked in a sickening haze. It's time to realize the cost of our global addiction to palm oil.




palm

Artists carve huge forest 'SOS' to highlight palm oil's destructive impact (Video)

Done in collaboration with local companies, residents and other organizations, the project's aim is to bring awareness to how palm oil production is negatively affecting humans and animals alike.




palm

Globalized Beef, Palm Oil & Timber Corporations Now Main Cause of Tropical Deforestation

Confirming what previous studies have shown, new research from the Union of Concerned Scientists shows that the main threats to tropical forests are no longer from




palm

It's primates versus palm oil in Africa

Since both require the same habitat, scientists are worried how primates will survive the expansion of industrial oil palm plantations.




palm

Malaysia struggles with its dubious reputation for palm oil

It resents the world for criticizing the industry, yet understands that some things need to change.




palm

Palm oil problem continues to plague big candy-makers

Hershey's, Nestle and Mars have not kept their promises when it comes to sourcing conflict-free palm oil.




palm

Photo: Squirrel peeks out from a palm

Our photo of the day comes from Los Angeles, California.




palm

Classic Automobile Collection Discovered in Denmark in an Incredible Barn Find - Campen Auktioner A/S - Specialbilauktion #482 Palmesøndag

Campen Auktioner A/S - Specialbilauktion #482 Palmesøndag