Welcome to an enlightening exploration into the world of macronutrients. These fundamental components of our diet — proteins, carbohydrates, and fats — play integral roles in our body’s physiological functions. While they’re clearly important to our health and well-being, they often remain shrouded in mystery for most of us. By learning more about macronutrients, you’ll understand how ... Read more

The post Macronutrients Unveiled: A Comprehensive Look at Their Roles in a Balanced Diet appeared first on Star Two.

velocityconf: Free webcast from our friends at @citrix 5/29 http://t.co/IOeY4U0wUP Learn to consolidate 40 load balancers and ADCs into single platform

Thanks to a change in the laws regulating gambling, land casinos are becoming popular in New Zealand. Today, the country has six casinos in total. Due to the relatively small number of casinos in the country, the industry focuses on offering superior quality as opposed to quantity. Of course, online gambling has grown too, providing […]

China is attempting a precarious balancing act Expert comment NCapeling 9 March 2023

In its efforts to maintain ties with both Russia and Europe, China is having to wade through conflicting interests and rapidly changing sentiments.

Precisely how far China will go in supporting Russia has been one of the most important questions of the war in Ukraine.

On 20 February, US secretary of state Antony Blinken warned China may soon provide arms (‘lethal support’) to Moscow. But then, on 24 February – the anniversary of Russia’s invasion – China released a position paper calling for a political settlement to end the conflict, tellingly omitting any mention of its ‘no-limits partnership’ with Russia.

China’s goal was to present itself as a neutral mediator. In fact, Beijing’s ties with Russia remain unchanged, even if this relationship has grown more exasperating for Chinese diplomats over the past year.

Their job is to continue striking a delicate balance, a task that is becoming increasingly difficult as Russian president Vladimir Putin doubles down on nuclear brinkmanship and reckless rhetoric.

Staying out of the Ukraine war

With Putin extolling the law of the jungle in its most brutal form, China must be careful not to involve itself too much in the conflict. After all, Russia is clearly losing, and China has high hopes of repairing ties with major European economies.

But Putin is of course keen to signal that China has his back. That is why he recently rolled out the red carpet for China’s top diplomat Wang Yi and then alluded to an (unconfirmed) upcoming visit by Chinese president Xi Jinping.

Such diplomatic developments allow him to present China’s ambivalent position as, in fact, an endorsement of the invasion. While the costs of aligning with Russia could easily outweigh the benefits for China, one must remember that China’s reasons for maintaining good relations with the Kremlin go beyond the war in Ukraine.

For starters, the two countries share a 2,672-mile (4,300-kilometer) border – roughly equivalent to the width of Europe – and the frontier’s exact location was not even finally settled until the beginning of this century, after generations of negotiations that included some 2,000 meetings.

Yet to this day, the spectre of the Sino-Soviet split in the 1950s and 1960s looms large on both sides and it is not likely to be exorcised anytime soon. With China focused on moves by the US and its allies in East Asia and the Indo-Pacific, it simply cannot afford sabre-rattling or unrest on its other borders.

Moreover, unlike the collective West, China’s foreign policy has always been shaped by interests rather than by values. Even with respect to Russia, the two countries’ bond is based mainly on shared resentment of US hegemony. By deepening their bilateral cooperation in recent years, they have been able to achieve a level of great-power status with which to counterbalance America.

But Putin’s misadventure in Ukraine has forced Xi and China’s newly minted Politburo to manage a new set of economic, financial, and political risks.

Russia’s war has left the West more firmly united than it has been in years. As China’s relations with the US have reached new lows, Chinese leaders want to avoid also alienating the European Union (EU), which is one of the country’s biggest trading partners.

This is why Xi and Chinese diplomats have been so careful not to accept the Kremlin’s talking points in full. Being isolated from the ‘collective West’ is not an attractive option for China, given its hopes of achieving a robust economic rebound after years of the zero-COVID policy.

Balancing Europe with the Global South

In seeking to keep diplomatic and trade channels open, China’s main tactic has been to reassure European countries that it will use its own ties with Russia to restrain Putin from deploying nuclear weapons.

At the same time, China is making a renewed push to strengthen its ties with the Global South where many countries do not see the war in Ukraine in the same stark moral terms as the West does.

The emphasis on energy and food security in China’s recent position paper may have struck a chord with developing countries that have been reeling from the war’s negative knock-on effects on their economies.

Chinese supply chains could tip the balance in Ukraine Expert comment NCapeling 29 March 2023

Disrupting supply chains of critical minerals to those supporting Ukraine could give China a key advantage in its wider international trade competition.

Direct military intervention from China into the war on Ukraine, with Chinese troops and airmen appearing at the front line, would be highly escalatory and highly unlikely.

Equipping Russia with weapons and equipment is much more likely – if indeed it hasn’t already happened – and considering the West is supplying armaments to Ukraine, a joust with western technologies would be an interesting development to follow.

But if Chinese weapons underperform in the heat of battle, this may have implications for the current situation with Taiwan and the US, as a poor outcome on the Ukraine front could give the West more confidence over the tensions in the South China Sea. And the use of Chinese weapons in Ukraine would also be a feast for Western technical intelligence to capture.

Creating economic disruption

A much more likely development for China is to put in place export controls on critical minerals for Western powers supplying arms to Ukraine. This is a significant lever which China has used before during its fishing dispute with Japan in 2010 when hi-tech industrial production in Japan was affected by shortages of China-sourced critical minerals. Once normal supplies were resumed, Japan started to stockpile critical mineral reserves.

In October 2020, the Chinese Communist Party (CCP) passed a new statute enabling – when necessary – restriction of critical mineral supplies to third party nations intending to use them for defence and security applications, adding a ‘versatile weapon to Beijing’s arsenal’ in its trade competition with the US.

That legal control has been applied to Lockheed Martin production of Taiwan-bound F-35s and it applies not only to critical minerals mined on the Chinese mainland, but also to Chinese-controlled enterprises within international supply chains, of which there are many.

Responding to any such restrictions by opening up new mines and setting up new supply chains can take more than a decade, so the countries involved may need to start stockpiling critical materials as Japan has been doing since 2010.

Commodity markets also need to be ready for some interesting price wobbles – a persistent problem in critical minerals extractives investment as is overcoming environmental, social, and governance (ESG) challenges in this new game of global supplies.

In addition, those markets include the London Metal Exchange, now owned by Hong Kong Exchanges & Clearing whose biggest shareholder is the Hong Kong government which is struggling to operate with complete independence from Beijing.

Splitting the West’s consensus

By extending the thinking on China’s potential to throttle global critical mineral supply chains and the ensuing latency of extraction from new mining resources, progress to the Paris Agreement 2050 goals on climate change will inevitably be affected.

Given there are no supply chain assurance mechanisms, such as distributed ledger technologies, in place within global mining supply chains, a key issue to overcome would be how the West assures China that critical mineral supplies are not destined for military applications.

But if China’s default position becomes a total refusal to supply client nations unless end-to-end assurances can be achieved to prove non-military use, the West’s aspirations regarding the Paris 2050 goals will certainly be put in jeopardy, or even made unachievable.

Expert

19 August 2020

Diana Samodova
Dec 1, 2020; 19:2139-2156
Technological Innovation and Resources

Trypsin is the protease of choice in bottom-up proteomics. However, its application can be limited by the amino acid composition of target proteins and the pH of the digestion solution. In this study we characterize ProAlanase, a protease from the fungus Aspergillus niger that cleaves primarily on the C-terminal side of proline and alanine residues. ProAlanase achieves high proteolytic activity and specificity when digestion is carried out at acidic pH (1.5) for relatively short (2 h) time periods. To elucidate the potential of ProAlanase in proteomics applications, we conducted a series of investigations comprising comparative multi-enzymatic profiling of a human cell line proteome, histone PTM analysis, ancient bone protein identification, phosphosite mapping and de novo sequencing of a proline-rich protein and disulfide bond mapping in mAb. The results demonstrate that ProAlanase is highly suitable for proteomics analysis of the arginine- and lysine-rich histones, enabling high sequence coverage of multiple histone family members. It also facilitates an efficient digestion of bone collagen thanks to the cleavage at the C terminus of hydroxyproline which is highly prevalent in collagen. This allows to identify complementary proteins in ProAlanase- and trypsin-digested ancient bone samples, as well as to increase sequence coverage of noncollagenous proteins. Moreover, digestion with ProAlanase improves protein sequence coverage and phosphosite localization for the proline-rich protein Notch3 intracellular domain (N3ICD). Furthermore, we achieve a nearly complete coverage of N3ICD protein by de novo sequencing using the combination of ProAlanase and tryptic peptides. Finally, we demonstrate that ProAlanase is efficient in disulfide bond mapping, showing high coverage of disulfide-containing regions in a nonreduced mAb.

South Africa After the Elections: Balancing Domestic and International Policy Priorities 16 May 2019 — 1:30PM TO 2:30PM Anonymous (not verified) 9 May 2019 Chatham House | 10 St James's Square | London | SW1Y 4LE

The government that emerges from the 8 May election in South Africa faces immediate domestic and international foreign policy demands. Attracting Foreign Direct Investment to stimulate job growth, accelerating anti-corruption and good governance efforts are at the forefront of the new government’s agenda.

International ambitions will be upgraded such as UN security council reform, maximizing South Africa’s G20, BRICS and IBSA membership and preparing for South Africa’s chairmanship of the African Union (AU) in 2020.

At this meeting, the speakers – Moeletsi Mbeki, deputy chairman of SAIIA and author with Nobantu Mbeki of A Manifesto for Social Change: How to Save South Africa, and Elizabeth Sidiropoulos, chief executive of SAIIA and currently co-editing a volume on A South African Foreign Policy for the 2020s which will be published in 2019 – will reflect on the election and discuss the new government’s domestic and international policy agenda. The meeting will be chaired by Ann Grant, former British High Commissioner to South Africa (2000-05) with past experience working for Oxfam, Standard Chartered Bank and Tullow Oil.

Wendi McLendon-Covey, David Alan Grier and Allison Tolman discuss the comedy in their harried medical characters on "St. Denis Medical," premiering Tuesday on NBC.

The state requested a waiver from the federal requirement in January. Failure to meet the 95-percent requirement can lead to funding penalties for states.

In addition to a delay, Wisconsin had to eliminate certain questions from its Smarter Balanced exam, after opting not to use the adaptive testing feature of the test.

The state decided that the Smarter Balanced Assessment Consortium offers it a chance to share assessment goals with neighboring states.

North Dakota and Wyoming state superintendents said this week that they will soon hire new testing vendors.

The Winnipeg Jets claimed Kaapo Kahkonen off waivers from the Avalanche on Tuesday afternoon

John M. Beggs
Dec 3, 2003; 23:11167-11177
BehavioralSystemsCognitive

A shipwreck discovered off New Zealand dates to a time before Cook's arrival

The noisy-but-shy bird, known as the hoiho, has earned the most votes for a second time amid threats to its survival

Ai-Da creates art using A.I. algorithms, cameras and robotic arms. Her abstract painting will be the first-ever artwork made by a humanoid robot to be sold at Sotheby's

Robust design helps withstand challenging competitive conditions as team takes first round in America 's Cup qualifying races

On 1 December, 22 women hiked Tongariro Alpine Crossing to raise awareness and funds for women and children trafficked in France and India.

About 110 men, women and children climbed five volcanoes in Auckland in the Freedom Climb New Zealand on Saturday, 16 August.

U.S. Rep. Glenn “GT” Thompson, chairman of the House Agriculture Committee, was honored with the 2024 Leadership Award presented by the Penn State Ag Council at its fall meeting in State College. Also recognized were members of the Pennsylvania in the Balance initiative and undergraduate student Jessica Herr.

Full-time remote instruction? In-person instruction? Or a hybrid model? Deciding among those three options can be an excruciating decision for school officials. But the choice many schools appear to be leaning toward is a hybrid model, at least for now.

A recent document signals a major change in instructional theory from the Reading Workshop creator, who previously pushed back on "phonics-centric people."

Patrick Walsh, an economist at the U.S. Environmental Protection Agency, will give the talk, “Distributional Impacts of Flood Adaptation and Infrastructure Funding in New Zealand,” at noon on Wednesday, Dec. 4, in 157 Hosler Building on Penn State's University Park campus. 

"I was even thrown out of a very big Tamil film at the time," said Vidya Balan

Madhuri Dixit and Vidya Balan shared screen space in the film for the first time

Vidya Balan's weight loss journey offers valuable insights into the connection between chronic inflammation and weight gain

The video of dosa served with aloo masala and tomato chutney has clocked 5.7 million views

As we move into 2025, AI continues to transform industries in unprecedented ways, driving efficiency, innovation, and productivity. But with this rapid advancement come critical ethical questions. How can we ensure that AI systems protect the rights and well-being of individuals?  Manufacturing and agriculture are two essential industries where answering [...]

Navigating AI ethics in manufacturing and agriculture: Balancing innovation with responsibility was published on SAS Voices by Kristi Boyd

Dear all,

Hi!

I'm trying to do a Harmonic Balance (HB) Large-Signal S-Parameter (LSSP) simulation to figure out the input impedance of a nonlinear circuit.

Through this simulation, what I want to know is the large-signal S11 only (not S12, S21 and S22).

So, I have simulated with only single port (PORT0) at input, but LSSP simulation is terminated and output log shows following text.

" Analysis `hb' was terminated prematurely due to an error "

The LSSP simulation does not proceed without second port.

Should I use floating second port (which is not necessary for my circuit) to succeed the LSSP simulation?

Does the LSSP simulation really need two ports?

Below figure is my HB LSSP simulation setup.

Additionally, Periodic S-Parameter (PSP) simulation using HB is succeeded with only single port.

What is the difference between PSP and LSSP simulations?

Stevens Mokgalapa talks about foreign investment opportunities and challenges in South Africa’s administrative capital, and the balancing act of development and environmental needs in the developing world.

wellington, new zealand — New Zealand's Prime Minister Christopher Luxon made a “formal and unreserved” apology in Parliament on Tuesday for the widespread abuse, torture and neglect of hundreds of thousands of children and vulnerable adults in care. “It was horrific. It was heartbreaking. It was wrong. And it should never have happened,” Luxon said, as he spoke to lawmakers and a public gallery packed with survivors of the abuse. An estimated 200,000 people in state, foster and faith-based care suffered “unimaginable” abuse over a period of seven decades, a blistering report released in July said at the end of the largest inquiry ever undertaken in New Zealand. They were disproportionately Māori, New Zealand’s Indigenous people. “For many of you it changed the course of your life, and for that, the government must take responsibility,” Luxon said. He said he was apologizing for previous governments too. In foster and church care — as well as in state-run institutions, including hospitals and residential schools — vulnerable people “should have been safe and treated with respect, dignity and compassion," he added. “But instead, you were subjected to horrific abuse and neglect and, in some cases, torture.” The findings of the six-year investigation believed to be the widest-ranging of comparable probes worldwide were a “national disgrace,” the inquiry's report said. New Zealand's investigation followed two decades of such inquiries around the globe as nations struggle to reckon with authorities’ transgressions against children removed from their families and placed in care. Of 650,000 children and vulnerable adults in New Zealand's state, foster, and church care between 1950 and 2019 — in a country that today has a population of 5 million — nearly a third endured physical, sexual, verbal or psychological abuse. Many more were exploited or neglected. “We will never know that true number,” Chris Hipkins, the leader of the opposition, told Parliament. “Many people entering into state and faith-based institutions were undocumented. Records were incomplete, they've gone missing, and in some cases, yes, they were deliberately destroyed.” In response to the findings, New Zealand’s government agreed for the first time that historical treatment of some children in a notorious state-run hospital amounted to torture — a claim successive administrations had rejected. “I am deeply sorry that New Zealand did not do better by you. I am sorry you were not believed when you came forward to report your abuse,” Luxon said. “I am sorry that many abusers were not made to face justice which meant that other people experienced abuse that could have been prevented.” His government was working on 28 of the inquiry's 138 recommendations, Luxon said, although he did not yet have concrete details on financial redress, which the inquiry had exhorted since 2021 and said could run to billions of dollars. Luxon was decried by some survivors and advocates earlier Tuesday for not divulging compensation plans alongside the apology. He told Parliament a single redress system would be established in 2025. He did not, however, suggest a figure for the amount the government expected to pay. “There will be a big bill, but it's nothing compared to the debt we owe those survivors and it must not be the reason for any further delay,” said Hipkins, the opposition leader. Survivors began to arrive at Parliament hours before the apology, having won spots in the public gallery — which only seats about 200 people — by ballot. Some were reluctant to accept the state's words, because they said the scale of the horror was not yet fully understood by lawmakers and public servants. Jeering was so loud during an apology from the country's solicitor-general that her speech was inaudible. Others called out or left the room in tears while senior public servants from relevant health and welfare agencies spoke before Luxon's remarks. Survivors invited to give speeches were required to do so before Luxon's apology — rather than in response to it, said Tu Chapman, one of those asked to speak. “Right now I feel alone and in utter despair at the way in which this government has undertaken the task of acknowledging all survivors,” she told a crowd at Parliament. The abuse "ripped families and communities apart, trapping many into a life of prison, incarceration, leaving many uneducated,” said Keith Wiffin — a survivor of abuse in a notorious state-run boys' home. “It has tarred our international reputation as an upholder of human rights, something this nation likes to dine out on.” The inquiry's recommendations included seeking apologies from state and church leaders, among them Pope Francis. It also endorsed creating offices to prosecute abusers and enact redress, renaming streets and monuments dedicated to abusers, reforming civil and criminal law, rewriting the child welfare system and searching for unmarked graves at psychiatric facilities. Its writers were scathing about how widely the abuse — and the identities of many abusers — were known about for years, with nothing done to stop it. “This has meant you have had to re-live your trauma over and over again,” said Luxon. “Agencies should have done better and must commit to doing so in the future.” He did not concede that public servants or ministers in his government who had denied state abuse was widespread when they served in previous administrations should lose their jobs. Luxon has also rejected suggestions by survivors that policies he has enacted which disproportionately target Māori — such as crackdowns on gangs and the establishment of military-style boot camps for young offenders — undermine his government's regret about the abuse. Māori are over-represented in prisons and gangs. In 2023, 68% of children in state care were Māori, although they are less than 20% of New Zealand's population. “It's not enough to say sorry,” said Fa’afete Taito, a survivor of violent abuse at another state-run home, and a former gang member. “It's what you do to heal the wounds of your actions and make sure it never happens again that really counts.”

Guddiga Doorashooyinka iyo xuduudaha dowlad goboleedka Jubaland ayaa doortay Guddoomiye, Guddoomiye kuxigeen iyo xoghaye. Guddiga doorashada…

The post Guddiga Doorashooyinka Jubaland oo doortay Guddoomiye iyo Kuxigeen appeared first on Horseed Media.

Xildhibaanada kumetela Puntland Baarlamaanka federaalka ayaa soo saaray warsaxaafadeed ay sheegeen in aysan qeyb ka aheyn…

The post Xildhibaano soo saarey warsaxaafadeed: “Waxaan ka digeynaa duulaanka Xasan Sheekh ee Puntland iyo Jubaland” appeared first on Horseed Media.

Ra’iisul Wasaaraha Xukuumadda Jamhuuriyadda Federaalka Soomaaliya, Mudane Xamsa Cabdi Barre, ayaa gelinkii danbe ee Salaasada ku…

The post Ergadii Dhexdhexaadinta Jubaland iyo Federaalka oo la kulmey Raysalwasaare Xamse appeared first on Horseed Media.

Several local government units have announced the suspension of classes on Wednesday, November 13, due to tropical cyclones "Ofel" (international name: Usagi) and "Nika" (international name: Toraji).

[Shabelle] Kismayo, Somalia -- The regional state of Jubaland has announced the suspension of all cooperation with the Federal Government of Somalia, escalating tensions over political and governance issues. The decision, made public early Sunday, marks a significant rift in the country's federal structure.

Slackliners set world record, balancing at 2,500 metres high between hot air balloons

Georgiev looks like a different goaltender in early November than he did last month.

Diets that claim to control excess oestrogen or stress hormones are all the rage on Instagram and TikTok. They could be good for us, just not for the reasons claimed