ram 11757b programming user guide By english.al-akhbar.com Published On :: 11757b programming user guide Full Article
ram to wire a switch to an outlet diagram By english.al-akhbar.com Published On :: to wire a switch to an outlet diagram Full Article
ram to wire an outlet in series diagram By english.al-akhbar.com Published On :: to wire an outlet in series diagram Full Article
ram to wire a garage diagram By english.al-akhbar.com Published On :: to wire a garage diagram Full Article
ram to wire switched outlets diagram By english.al-akhbar.com Published On :: to wire switched outlets diagram Full Article
ram to wire a two gang light switch diagram By english.al-akhbar.com Published On :: to wire a two gang light switch diagram Full Article
ram Loan No. 2972-PAK: Power Distribution Enhancement Investment Program, Tranche-III [ADB-TRANCHE-III-MEPCO-01] By www.adb.org Published On :: Full Article
ram Loan No. 2924-IND: Uttarakhand Power Sector Investment Program - Project 4 [ICB No. 3-P/ADB/PTCUL/2012-13] By www.adb.org Published On :: Full Article
ram Loan No. 3411-AZE: Water Supply and Sanitation Investment Program - Tranche 4 [MFF42408-044-T4-ICB-1.02] By www.adb.org Published On :: Full Article
ram Loan No. 42486-IND: Madhya Pradesh Urban Services Improvement Program [MPUSIP 6D REBIDDING] By www.adb.org Published On :: Full Article
ram Loan Nos. 3076/3077-PNG: Highland Region Road Improvement Investment Program [CSTB No. 2946] By www.adb.org Published On :: Full Article
ram Loan No. 42401-AZE: Power Distribution Enhancement Investment Program - Tranche 1 [AI/ADB-10.1 and AI/ADB-10.2] By www.adb.org Published On :: Full Article
ram Loan No. 3203-PAK: Power Transmission Enhancement Investment Program Tranche 4 [ADB-79-2015] EXTENDED By www.adb.org Published On :: Full Article
ram Loan No. 2972-PAK: Power Distribution Enhancement Investment Program - Tranche 3 [LESCO-10-2013] By www.adb.org Published On :: Full Article
ram Loan No. 2830-IND: Madhya Pradesh Energy Efficiency Improvement Investment Program – Tranche 2 [MD / WZ / 06 / PUR / ADB /993] By www.adb.org Published On :: Full Article
ram Climate and Disaster Resilience Enhancement Program (Subprogram 1) By www.adb.org Published On :: 2024-10-29 The proposed program will support the enhancement of Pakistan's resilience to disasters triggered by natural hazards and the impacts of climate change. Through an integrated approach, the program will support (i) strengthened institutional capacity for strategy, planning, and response; (ii) increased investment in disaster risk reduction (DRR) and climate resilience; and (iii) enhanced disaster risk financing (DRF) using a risk-layered approach. Full Article
ram Fiscal Sustainability and Financial Markets Development Program (Subprogram 2) By www.adb.org Published On :: 2024-10-31 Full Article
ram Health Care Quality Improvement Program By www.adb.org Published On :: 2024-11-06 The program aims to improve the quality of health care as stipulated in the Government Program, 2021-2026, Health Sector Strategy 2023-2026, the UHI Concept Paper, and the Quality of Care Strategy 2022-2026. Full Article
ram Seismic Safety Improvement Program 3 By www.adb.org Published On :: 2025 The Republic of Armenia is located at the intersection of major tectonic faults, making it highly prone to seismic activity. The devastation of the 1988 Spitak earthquake claimed about 25,000 lives, including 6,000 school children; left 517,000 people homeless, destroyed 190 schools and many urban infrastructures; and incurred direct economic losses of $15 billion-$20 billion. The recent 7.8-magnitude earthquake in neighboring Trkiye and Syria in 2023 is a wake-up call for Armenia, posing a significant threat to the country. rkiye and Syria in 2023 is a wake-up call for Armenia, posing a significant threat to the country. Full Article
ram Resilient Amu Darya River Basin Sector Development Program By www.adb.org Published On :: 2025 The proposed project will undertake a long-term and strategic approach to deliver climate adaptive solutions for water resources management in the Amu Darya River Basins in Uzbekistan. Predicted climate change impacts include increased temperatures, increased frequency and severity of extreme events such as floods and droughts, and a reduction of water availability and increased variability of water flows in the major river basins. Decreasing availability and increased water requirements by different sectors are leading to a growing seasonal and absolute supply-demand gap. Full Article
ram MFF: Green and Resilience Financing Facility Investment Program By www.adb.org Published On :: 2026 The proposed program is a large-scale transformative and integrated initiative addressing the constraints. It aims to bridge the financing, capacity, institutional, and technical gaps in implementing the NAP and adaptation measures mentioned in the NDC and GRID while promoting mitigation, biodiversity, air pollution, and food security as co-benefits. Full Article
ram Paramotorists collect rare plant species from Peruvian desert oases By www.newscientist.com Published On :: Wed, 09 Oct 2024 09:00:47 +0100 Kew scientists use paramotorists to collect rare plant species from Peruvian desert oases Full Article
ram Richard Dawkins's latest crams gorgeous writing in an ill-fitting box By www.newscientist.com Published On :: Wed, 09 Oct 2024 19:00:00 +0100 A new book from the science-writing legend is an Attenborough-esque romp through some of the wonders of the natural world. Just beware the title's misfiring metaphor Full Article
ram Black holes scramble information – but may not be the best at it By www.newscientist.com Published On :: Mon, 06 May 2024 14:00:47 +0100 Information contained within quantum objects gets scrambled when they interact. Physicists have now derived a speed limit for this process, challenging the idea that black holes are the fastest data scramblers Full Article
ram Quantum holograms can send messages that disappear By www.newscientist.com Published On :: Fri, 30 Aug 2024 21:12:22 +0100 Entangled particles of light can transmit holographic images that can be selectively erased, allowing for secure communications that can also be deleted Full Article
ram Dramatic images show the dark side of cobalt mining boom By www.newscientist.com Published On :: Wed, 14 Aug 2024 19:00:00 +0100 Pascal Maitre's photos from the Democratic Republic of Congo detail the problems arising as demand for cobalt grows Full Article
ram A dramatic twist to the Gaia hypothesis By www.newscientist.com Published On :: Wed, 21 Aug 2024 19:00:00 +0100 James Lovelock's hypothesis that our planet is a living entity is well known. Ferris Jabr's new book Becoming Earth takes it a step further Full Article
ram Chilling news adds fresh meaning to 2018 Arctic horror drama By www.newscientist.com Published On :: Wed, 30 Oct 2024 18:00:00 +0000 A new study amplifies the horror of an excellent series about the doomed Franklin expedition. The Terror is a worthy tribute to the lost sailors, says Bethan Ackerley Full Article
ram A lost branch of the river Nile flowed past the pyramids of Egypt By www.newscientist.com Published On :: Thu, 16 May 2024 17:00:12 +0100 Soil core samples show an ancient riverbed under the desert near many Egyptian pyramids, revealing an ancient waterway that dried up thousands of years ago Full Article
ram Egyptian pyramid may have been built using a water-powered elevator By www.newscientist.com Published On :: Wed, 24 Jul 2024 20:20:04 +0100 Ancient Egyptians may have relied on a vertical shaft that could be filled with water, along with a network of water channels and filtration structures, to build the Step Pyramid of Djoser 4500 years ago Full Article
ram Chilling news adds fresh meaning to 2018 Arctic horror drama By www.newscientist.com Published On :: Wed, 30 Oct 2024 18:00:00 +0000 A new study amplifies the horror of an excellent series about the doomed Franklin expedition. The Terror is a worthy tribute to the lost sailors, says Bethan Ackerley Full Article
ram Walking School Bus Programs Take Off By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Walking School Bus Programs Take OffCategory: Health NewsCreated: 8/23/2011 11:01:00 AMLast Editorial Review: 8/23/2011 12:00:00 AM Full Article
ram Ebola: A Medical Drama Unfolds By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Ebola: A Medical Drama UnfoldsCategory: Health NewsCreated: 8/23/2014 11:00:00 AMLast Editorial Review: 8/25/2014 12:00:00 AM Full Article
ram False-Positive Mammogram Result Traumatic for Most Women: Study By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: False-Positive Mammogram Result Traumatic for Most Women: StudyCategory: Health NewsCreated: 8/26/2015 12:00:00 AMLast Editorial Review: 8/26/2015 12:00:00 AM Full Article
ram 'Pretend Mommy' Program Doesn't Deter Teen Pregnancy By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: 'Pretend Mommy' Program Doesn't Deter Teen PregnancyCategory: Health NewsCreated: 8/25/2016 12:00:00 AMLast Editorial Review: 8/26/2016 12:00:00 AM Full Article
ram Looking for a Plastic Surgeon on Instagram? Beware By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Looking for a Plastic Surgeon on Instagram? BewareCategory: Health NewsCreated: 8/30/2017 12:00:00 AMLast Editorial Review: 8/30/2017 12:00:00 AM Full Article
ram Newborns' Immune Systems Ramp Up After Birth By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Newborns' Immune Systems Ramp Up After BirthCategory: Health NewsCreated: 8/24/2018 12:00:00 AMLast Editorial Review: 8/27/2018 12:00:00 AM Full Article
ram 'Dramatic Resurgence' of Measles in Europe: WHO By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: 'Dramatic Resurgence' of Measles in Europe: WHOCategory: Health NewsCreated: 8/29/2019 12:00:00 AMLast Editorial Review: 8/29/2019 12:00:00 AM Full Article
ram Gabapentin vs. Tramadol By www.medicinenet.com Published On :: Fri, 22 Jul 2022 00:00:00 PDT Title: Gabapentin vs. TramadolCategory: MedicationsCreated: 3/22/2018 12:00:00 AMLast Editorial Review: 7/22/2022 12:00:00 AM Full Article
ram Ondansetron (Zofran) vs. Dramamine By www.medicinenet.com Published On :: Tue, 2 Aug 2022 00:00:00 PDT Title: Ondansetron (Zofran) vs. DramamineCategory: MedicationsCreated: 7/24/2019 12:00:00 AMLast Editorial Review: 8/2/2022 12:00:00 AM Full Article
ram tobramycin By www.medicinenet.com Published On :: Tue, 2 Aug 2022 00:00:00 PDT Title: tobramycinCategory: MedicationsCreated: 8/2/2022 12:00:00 AMLast Editorial Review: 8/2/2022 12:00:00 AM Full Article
ram tramadol By www.medicinenet.com Published On :: Tue, 2 Aug 2022 00:00:00 PDT Title: tramadol Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 8/2/2022 12:00:00 AM Full Article
ram Tramadol vs. Hydrocodone By www.medicinenet.com Published On :: Fri, 5 Aug 2022 00:00:00 PDT Title: Tramadol vs. HydrocodoneCategory: MedicationsCreated: 4/24/2017 12:00:00 AMLast Editorial Review: 8/5/2022 12:00:00 AM Full Article
ram Theoretical framework for the difference of two negative binomial distributions and its application in comparative analysis of sequencing data [METHODS] By genome.cshlp.org Published On :: 2024-10-29T06:46:08-07:00 High-throughput sequencing (HTS) technologies have been instrumental in investigating biological questions at the bulk and single-cell levels. Comparative analysis of two HTS data sets often relies on testing the statistical significance for the difference of two negative binomial distributions (DOTNB). Although negative binomial distributions are well studied, the theoretical results for DOTNB remain largely unexplored. Here, we derive basic analytical results for DOTNB and examine its asymptotic properties. As a state-of-the-art application of DOTNB, we introduce DEGage, a computational method for detecting differentially expressed genes (DEGs) in scRNA-seq data. DEGage calculates the mean of the sample-wise differences of gene expression levels as the test statistic and determines significant differential expression by computing the P-value with DOTNB. Extensive validation using simulated and real scRNA-seq data sets demonstrates that DEGage outperforms five popular DEG analysis tools: DEGseq2, DEsingle, edgeR, Monocle3, and scDD. DEGage is robust against high dropout levels and exhibits superior sensitivity when applied to balanced and imbalanced data sets, even with small sample sizes. We utilize DEGage to analyze prostate cancer scRNA-seq data sets and identify marker genes for 17 cell types. Furthermore, we apply DEGage to scRNA-seq data sets of mouse neurons with and without fear memory and reveal eight potential memory-related genes overlooked in previous analyses. The theoretical results and supporting software for DOTNB can be widely applied to comparative analyses of dispersed count data in HTS and broad research questions. Full Article
ram The chromatin tapestry as a framework for neurodevelopment [MINI-REVIEW] By genome.cshlp.org Published On :: 2024-10-29T06:46:07-07:00 The neuronal nucleus houses a meticulously organized genome. Within this structure, genetic material is not simply compacted but arranged into a precise and functional 3D chromatin landscape essential for cellular regulation. This mini-review highlights the importance of this chromatin landscape in healthy neurodevelopment, as well as the diseases that occur with aberrant chromatin architecture. We discuss insights into the fundamental mechanistic relationship between histone modifications, DNA methylation, and genome organization. We then discuss findings that reveal how these epigenetic features change throughout normal neurodevelopment. Finally, we highlight single-gene neurodevelopmental disorders that illustrate the interdependence of epigenetic features, showing how disruptions in DNA methylation or genome architecture can ripple across the entire epigenome. As such, we emphasize the importance of measuring multiple chromatin architectural aspects, as the disruption of one mechanism can likely impact others in the intricate epigenetic network. This mini-review underscores the vast gaps in our understanding of chromatin structure in neurodevelopmental diseases and the substantial research needed to understand the interplay between chromatin features and neurodevelopment. Full Article
ram Implementation of an Opt-Out Outpatient HIV Screening Program By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Background: Screening rates for Human Immunodeficiency Virus (HIV) remain low despite guidelines by both the CDC and USPSTF recommending that all adolescents and adults be screened at least once. The aim of this quality improvement study was to increase HIV screening among eligible patients. Methods: This quality improvement study assessed the impact of interventions to increase HIV screening in an outpatient population at a large urban safety-net hospital. Outcomes were compared from the preintervention (December 2020 to November 2021) to postintervention years (December 2021 to November 2022). Stepwise electronic alerts to prompt HIV screening paired with provider financial incentives were implemented. The proportion of eligible individuals screened for HIV were compared after intervention implementation. Results: Average monthly HIV screening increased from 506 ± 97 to 2484 ± 663 between the pre- and postintervention periods, correlating to a 5.1-fold increase in screening (7.8% to 39.8%, P < .01). Increases were seen across all ages, and those aged 55 to 64 and 65+ had the highest relative increase in screening at 7.5 and 9.3-fold, respectively (P < .01). Screening rates increased for Hispanics (7.9% preintervention vs 43.6% postintervention, P < .01). In the pre- and postintervention periods, 41 patients with new HIV diagnoses were identified (13 preintervention and 28 postintervention) and 85.4% were linked to care within 30 days. Conclusions: Stepwise interventions targeted at primary care clinicians are an effective way to increase HIV screening rates, particularly in older demographics. Earlier HIV diagnosis coupled with linkage to care is an important strategy in ending the HIV epidemic. Full Article
ram Perspectives on Using Race in Pulmonary Function Testing: A National Survey of Fellows and Program Directors By rc.rcjournal.com Published On :: 2024-10-25T05:44:12-07:00 BACKGROUND:Pulmonary function tests (PFTs) have historically used race-specific prediction equations. The recent American Thoracic Society guidelines recommend the use of a race-neutral approach in prediction equations. There are limited studies centering the opinions of practicing pulmonologists on the use of race in spirometry. Provider opinion will impact adoption of the new guideline. The aim of this study was to ascertain the beliefs of academic pulmonary and critical care providers regarding the use of race as a variable in spirometry prediction equations.METHODS:We report data from 151 open-ended responses from a voluntary, nationwide survey (distributed by the Association of Pulmonary Critical Care Medicine Program Directors) of academic pulmonary and critical care providers regarding the use of race in PFT prediction equations. Responses were coded using inductive and deductive methods, and a thematic content analysis was conducted.RESULTS:There was a balanced distribution of opinions among respondents supporting, opposing, or being unsure about the incorporation of race in spirometry prediction equations. Responses demonstrated a wide array of understanding related to the concept and definition of race and its relationship to physiology.CONCLUSIONS:There was no consensus among providers regarding the use of race in spirometry prediction equations. Concepts of race having biologic implications persist among pulmonary providers and will likely affect the uptake of the Global Lung Function Initiative per the American Thoracic Society guidelines. Full Article
ram A Strategic Guide to Improve and De-Risk Vaccine Development: CEPIs CMC Framework By journal.pda.org Published On :: 2024-10-22T08:20:35-07:00 The Coalition for Epidemic Preparedness Innovations (CEPI) has developed a robust CMC (Chemistry, Manufacturing, and Controls) Framework to enhance the likelihood of successful vaccine development. This Framework serves as a comprehensive guide, aiding developers in building effective strategies to overcome the challenges posed by the different phases of vaccine development, including the ones often referred to as the "valleys of death". The Framework lists stage-appropriate deliverables, categorized and refined, spanning five key areas: manufacturing process, formulation and stability, analytics, supply chain, and compliance. By emphasizing the critical aspects of CMC development, CEPI's objective is to expedite the progression of vaccine candidates from research to deployment, reducing delays, mitigating risks, and optimizing the overall development process, all while upholding uncompromising quality standards, ultimately increasing the probability of success. Full Article
ram Abolished frameshifting for predicted structure-stabilizing SARS-CoV-2 mutants: implications to alternative conformations and their statistical structural analyses [ARTICLE] By rnajournal.cshlp.org Published On :: 2024-10-16T07:18:13-07:00 The SARS-CoV-2 frameshifting element (FSE) has been intensely studied and explored as a therapeutic target for coronavirus diseases, including COVID-19. Besides the intriguing virology, this small RNA is known to adopt many length-dependent conformations, as verified by multiple experimental and computational approaches. However, the role these alternative conformations play in the frameshifting mechanism and how to quantify this structural abundance has been an ongoing challenge. Here, we show by DMS and dual-luciferase functional assays that previously predicted FSE mutants (using the RAG graph theory approach) suppress structural transitions and abolish frameshifting. Furthermore, correlated mutation analysis of DMS data by three programs (DREEM, DRACO, and DANCE-MaP) reveals important differences in their estimation of specific RNA conformations, suggesting caution in the interpretation of such complex conformational landscapes. Overall, the abolished frameshifting in three different mutants confirms that all alternative conformations play a role in the pathways of ribosomal transition. Full Article