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We're still untangling Ramanujan's mathematics 100 years after he died

Srinivisa Ramanujan’s ideas seemed to come from a parallel universe and mathematicians are still getting to grips with them today, say Ken Ono and Robert Schneider




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Drinking coffee appears to cause epigenetic changes to your DNA

Coffee has been linked to changes on our DNA that affect how active certain genes are. The finding may help explain some of coffee's touted health benefits




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An ancient river on Mars may have flowed for 100,000 years

We’ve found a 200-metre cliff in Mars's Hellas basin, the first evidence of a river that flowed on the planet for more than 100,000 years




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Bank of England predicts worst slump in 300 years

The Bank of England says the UK faces its worst slump in 300 years, but on Thursday held off from any moves on rates or bond buying. Julian Satterthwaite reports.




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Deep Brain Stimulation May Relieve Ringing in the Ears: Study

Title: Deep Brain Stimulation May Relieve Ringing in the Ears: Study
Category: Health News
Created: 10/7/2019 12:00:00 AM
Last Editorial Review: 10/8/2019 12:00:00 AM




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Music Career Might Bring Ringing in the Ears

Title: Music Career Might Bring Ringing in the Ears
Category: Health News
Created: 11/22/2019 12:00:00 AM
Last Editorial Review: 11/25/2019 12:00:00 AM




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Ring in the New Year Without Ringing in Your Ears

Title: Ring in the New Year Without Ringing in Your Ears
Category: Health News
Created: 12/31/2019 12:00:00 AM
Last Editorial Review: 12/31/2019 12:00:00 AM




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Higher Vitamin D, Better Golden Years?

Title: Higher Vitamin D, Better Golden Years?
Category: Health News
Created: 4/26/2010 11:08:00 AM
Last Editorial Review: 4/26/2010 11:08:04 AM




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50 Years of Data Confirm Benefit of Antipsychotics

Title: 50 Years of Data Confirm Benefit of Antipsychotics
Category: Health News
Created: 5/3/2012 11:00:00 AM
Last Editorial Review: 5/3/2012 12:00:00 AM




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Training Programs Protect Young Athletes From ACL Tears: Report

Title: Training Programs Protect Young Athletes From ACL Tears: Report
Category: Health News
Created: 4/28/2014 9:35:00 AM
Last Editorial Review: 4/28/2014 12:00:00 AM




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Psychiatric Scars of Wartime Brain Injury May Linger for Years

Title: Psychiatric Scars of Wartime Brain Injury May Linger for Years
Category: Health News
Created: 5/1/2017 12:00:00 AM
Last Editorial Review: 5/2/2017 12:00:00 AM




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Depression's Gender Gap Shows Up in Pre-Teen Years

Title: Depression's Gender Gap Shows Up in Pre-Teen Years
Category: Health News
Created: 5/2/2017 12:00:00 AM
Last Editorial Review: 5/3/2017 12:00:00 AM




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Take These 5 Steps to Live 10 Extra Years

Title: Take These 5 Steps to Live 10 Extra Years
Category: Health News
Created: 4/30/2018 12:00:00 AM
Last Editorial Review: 4/30/2018 12:00:00 AM




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'Ringing in the Ears' May Drive Some to the Brink of Suicide

Title: 'Ringing in the Ears' May Drive Some to the Brink of Suicide
Category: Health News
Created: 5/2/2019 12:00:00 AM
Last Editorial Review: 5/3/2019 12:00:00 AM




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As Coronavirus Fears Surge, Keep Cleaning Products Away From Children

Title: As Coronavirus Fears Surge, Keep Cleaning Products Away From Children
Category: Health News
Created: 4/27/2020 12:00:00 AM
Last Editorial Review: 4/27/2020 12:00:00 AM




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In Small Study, Rheumatoid Arthritis Drug Appears to Help COVID-19 Patients

Title: In Small Study, Rheumatoid Arthritis Drug Appears to Help COVID-19 Patients
Category: Health News
Created: 5/7/2020 12:00:00 AM
Last Editorial Review: 5/8/2020 12:00:00 AM




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Ten Years After: PMC Milestone Featured in NLM in Focus!

PMC marked its 10th anniversary in 2010 with a celebratory event at its annual Advisory Committee meeting, held at the National Library of Medicine last June. This milestone event was recently featured in the February 17th edition of NLM In Focus, in an article NLM Milestones: The Hits Just Keep on Coming. For more information on the ten years of PMC, see the article in the May-June issue of the NLM Technical Bulletin.




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Nose Jobs Make Women Look Years Younger, Robot Says

Title: Nose Jobs Make Women Look Years Younger, Robot Says
Category: Health News
Created: 1/28/2020 12:00:00 AM
Last Editorial Review: 1/28/2020 12:00:00 AM




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Pot Use Among U.S. Seniors Nearly Doubled in 3 Years

Title: Pot Use Among U.S. Seniors Nearly Doubled in 3 Years
Category: Health News
Created: 2/24/2020 12:00:00 AM
Last Editorial Review: 2/25/2020 12:00:00 AM




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Ahmed A, Fend PI, Gaensbauer JT, Reves RR, Khurana R, Salcedo K, Punnoose R, Katz DJ, for the TUBERCULOSIS EPIDEMIOLOGIC STUDIES CONSORTIUM. Interferon-{gamma} Release Assays in Children <15 Years of Age. Pediatrics. 2020:145(1):e20191930




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Rates and Stability of Mental Health Disorders in Children Born Very Preterm at 7 and 13 Years

OBJECTIVES:

Children born very preterm (VPT) are at an increased risk of developing mental health (MH) disorders. Our aim for this study was to assess rates of MH disorders in children born VPT and term at 13 years of age and stability of MH disorders between ages 7 and 13 years by using a diagnostic measure.

METHODS:

Participants were from the Victorian Infant Brain Study longitudinal cohort and included 125 children born VPT (<30 weeks’ gestational age and/or <1250 g) and 49 children born term (≥37 weeks’ gestational age) and their families. Participants were followed-up at both 7 and 13 years, and the Development and Well-Being Assessment was administered to assess for MH disorders.

RESULTS:

Compared with term peers, 13-year-olds born VPT were more likely to meet criteria for any MH disorder (odds ratio 5.9; 95% confidence interval 1.71–20.03). Anxiety was the most common disorder in both groups (VPT = 14%; term = 4%), whereas attention-deficit/hyperactivity disorder carried the greatest differential elevated risk (odds ratio 5.6; 95% confidence interval 0.71–43.80). Overall rates of MH disorders remained stable between 7 and 13 years, although at an individual level, many participants shifted in or out of diagnostic categories over time.

CONCLUSIONS:

Children born VPT show higher rates of MH disorders than their term peers, with changing trajectories over time. Findings highlight the importance of early identification and ongoing assessment to support those with MH disorders in this population.




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Early Childhood Factors Associated With Peer Victimization Trajectories From 6 to 17 Years of Age

OBJECTIVES:

To describe (1) the developmental trajectories of peer victimization from 6 to 17 years of age and (2) the early childhood behaviors and family characteristics associated with the trajectories.

METHODS:

We used data from 1760 children enrolled in the Quebec Longitudinal Study of Child Development, a population-based birth cohort. Participants self-reported peer victimization at ages 6, 7, 8, 10, 12, 13, 15, and 17 years. Participants’ behavior and family characteristics were measured repeatedly between ages 5 months and 5 years.

RESULTS:

We identified 4 trajectories of peer victimization from 6 to 17 years of age: low (32.9%), moderate-emerging (29.8%), childhood-limited (26.2%), and high-chronic (11.1%). Compared with children in the low peer victimization trajectory, children in the other 3 trajectories were more likely to exhibit externalizing behaviors in early childhood, and those in the high-chronic and moderate-emerging trajectories were more likely to be male. Paternal history of antisocial behavior was associated with moderate-emerging (odds ratio [OR] = 1.54; 95% confidence interval [CI] = 1.09–2.19) and high-chronic (OR = 1.93; 95% CI = 1.25–2.99) relative to low peer victimization. Living in a nonintact family in early childhood was associated with childhood-limited (OR = 1.48; 95% CI = 1.11–1.97) and high-chronic (OR = 1.59; 95% CI = 1.09–2.31) relative to low peer victimization.

CONCLUSIONS:

Early childhood externalizing behaviors and family vulnerabilities were associated with the development of peer victimization. Some children entered the cascade of persistent peer victimization at the beginning of primary school. Support to these children and their families early in life should be an important component of peer victimization preventive interventions.




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Breastfeeding and Mortality Under 2 Years of Age in Sub-Saharan Africa

BACKGROUND:

Several studies have investigated the association of breastfeeding status with offspring mortality in Africa, but most studies were from one center only or had limited statistical power to draw robust conclusions.

METHODS:

Data came from 75 nationally representative cross-sectional Demographic and Health Surveys in 35 countries in sub-Saharan Africa conducted between 2000 and 2016. Our study relied on 217 112 individuals aged 4 days to 23 months for breastfeeding pattern analysis, 161 322 individuals aged 6 to 23 months for breastfeeding history analysis, and 104 427 individuals aged 12 to 23 months for breastfeeding duration analysis.

RESULTS:

Compared with children aged 4 days to 23 months exclusively breastfed in the first 3 days of life, those not breastfed had a high risk of mortality at <2 years of age (odds ratio [OR] = 13.45; 95% confidence interval [CI] = 11.43–15.83). Young children who were predominantly breastfed or partially breastfed had moderately increased risk of mortality at <2 years of age (OR = 1.11, 95% CI = 1.03–1.21 for predominant pattern; OR = 1.12, 95% CI = 0.99–1.27 for partial pattern). Compared with children aged 6 to 23 months who were breastfed within the first 6 months of life, those not breastfed had a high risk of mortality (OR = 5.65; 95% CI = 4.27–7.47). Compared with children aged 12 to 23 months who were breastfed for ≥6 months, those who were breastfed for shorter periods had a higher risk of mortality (OR = 2.78, 95% CI = 1.45–5.32 for duration of <3 months; OR = 5.28, 95% CI = 3.24–8.61 for those who were not breastfed).

CONCLUSIONS:

Our findings support exclusive breastfeeding during the first 6 months of life and continued breastfeeding up to 2 years of age recommended by the World Health Organization for reducing mortality of children <2 years old in sub-Saharan Africa.




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Impairment in Baroreflex Sensitivity in Recent-Onset Type 2 Diabetes Without Progression Over 5 Years

Impaired baroreflex sensitivity (BRS) predicts cardiovascular mortality and is prevalent in long-term diabetes. We determined spontaneous BRS in patients with recent-onset diabetes and its temporal sequence over 5 years by recording beat-to-beat blood pressure and R-R intervals over 10 min. Four time domain and four frequency domain BRS indices were computed in participants from the German Diabetes Study baseline cohort with recent-onset type 1/type 2 diabetes (n = 206/381) and age-matched glucose-tolerant control subjects (control 1/control 2: n = 65/83) and subsets of consecutive participants with type 1/type 2 diabetes who reached the 5-year follow-up (n = 84/137). Insulin sensitivity (M-value) was determined using a hyperinsulinemic-euglycemic clamp. After appropriate adjustment, three frequency domain BRS indices were reduced in type 2 diabetes compared with control 2 and were positively associated with the M-value and inversely associated with fasting glucose and HbA1c (P < 0.05), whereas BRS was preserved in type 1 diabetes. After 5 years, a decrease in one and four BRS indices was observed in patients with type 1 and type 2 diabetes, respectively (P < 0.05), which was explained by the physiologic age-dependent decline. Unlike patients with well-controlled recent-onset type 1 diabetes, those with type 2 diabetes show early baroreflex dysfunction, likely due to insulin resistance and hyperglycemia, albeit without progression over 5 years.




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Smoking pack years calculator




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The Wass report: moving forward 3 years on




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Pregnancy-adapted YEARS algorithm: can YEARS do more for pregnant women?

Venous thromboembolism (VTE), as a term that encompasses pulmonary embolism (PE) and deep vein thrombosis (DVT), is one of the leading causes of maternal morbidity and mortality [1], especially in developed countries, where PE takes second place after complications of hypertensive disorders [2]. When compared to non-pregnant women of similar age, pregnant women have an approximately four to five times higher risk of VTE [3], with an incidence of 1 in 1000 pregnancies [4]. Approximately 20–25% of VTE cases are caused by PE and 75–80% of cases are caused by DVT [5]. About 60% of DVT occurs antepartum, with the highest risk of antepartum pregnancy-associated VTE being in the third trimester.However, about 60% of PE occurs postpartum [3].




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Celebrating 35 Years of the AJNR: March 1985 edition [35 YEARS AGO IN AJNR]




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A lazy fix 20 years ago means the Y2K bug is taking down computers now

The millennium bug is back with a vengeance, after programmers in the 1990s simply pushed the problem back by 20 years




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UK nuclear fusion reactor will fire up for the first time in 23 years

Within months researchers will attempt to create a ball of plasma hotter than the sun inside the Joint European Torus, a doughnut-shaped machine in south-east England




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UK government approves Huawei 5G deal despite security fears

Chinese telecomms firm Huawei will be allowed to provide technology for key parts of the UK's super-fast 5G infrastructure, prime minister Boris Johnson has said, despite opposition from the US




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After Five Bloody Years in Syria, Russia Is Turning Against Iran—and Assad

Photo Illustration by The Daily Beast/Getty

GAZIANTEP, Turkey—After five years fighting to preserve Bashar al-Assad’s regime in Syria, Russia now appears inclined to dispose of its infamous client. Assad’s persistent brutality and corruption, and his inability to establish even the semblance of a functioning state, has grown to be a burden Moscow would prefer not to bear.

And then there’s the problem of Iran. Assad, members of his family, and his Alawite clansmen enjoy close, perhaps unbreakable, bonds to the regime in Tehran and to Iranian-backed militias in Syria. All of which undermines Moscow’s primary mission there: to rehabilitate the Assad regime as a symbol of stability capable of attracting hundreds of billions of dollars of foreign investment for reconstruction, which Russian firms would then be poised to receive. 

As long as Assad’s relatives continue to function as a mafia and give free rein to Iranian troops using Syria as base of operations to threaten Israel and plan attacks against U.S. troops in Iraq, those countries likely to foot the bill for Syrian reconstruction—the nations of Europe and the Gulf—are unlikely to come up with the cash. 

Read more at The Daily Beast.




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Unemployment fears mount in UK holiday hotspots with mass job cuts predicted



BRITAIN'S summer holiday destinations will face some of the biggest economic hits of the coronavirus pandemic with fears of massive job losses in coastal communities, a study has claimed.




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Rafael Nadal: ATP Tour chairman responds to 2020 season cancellation fears



Rafael Nadal revealed this week he was doubtful there will be further tennis in 2020.




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Mars may have formed 15 million years later than we thought

Young Mars may have endured a series of huge collisions that smashed its mantle, throwing off our measurements of when it formed by up to 15 million years




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Bombing asteroid Ryugu reveals it is a spritely 9 million years old

The Hayabusa-2 spacecraft bombed the asteroid Ryugu in April. Analysing the crater it left behind suggests Ryugu is a relative youngster at 9 million years old




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An ancient river on Mars may have flowed for 100,000 years

We’ve found a 200-metre cliff in Mars's Hellas basin, the first evidence of a river that flowed on the planet for more than 100,000 years




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Fairfax-APN fears outlined

New Zealand’s competition watchdog has cited areas of overlap from a Fairfax-APN merger.




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RPGCast – Episode 279: “RPGamer: The After Years”

RPGamer’s hosts battle through various ailments to bring you this week’s show. Jon gets ready for National StreetPass day, Anna gets stops Activision Blizzard from...




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Ray of hope as Scots armed forces veterans wait two years for a mental health plan

ARMED forces veterans are facing a threat from an enemy they cannot see.




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Nostalgic News: ‘Let It Be’ by The Beatles was released 50 years ago

Bailey Williams reflects on the final Beatles album.




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Ousted Scientist Tears Up While Ripping Trump Coronavirus Response: 'We Could've Done Something And We Didn't'

Trump administration whistleblower Rick Bright teared up while ripping the Trump's response to the coronavirus: "We could've done something and we didn't."




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Britney Spears Updates Glory Album Cover to Celebrate 2016 Record Hitting #1 on iTunes

Some fans think the new album art was released in anticipation of a rumored platinum edition of Glory.




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Martian Dynamo was Active between 4.5 and 3.7 Billion Years Ago, Study Says

A planet’s global magnetic field arises from a so-called dynamo — a flow of molten metal within the planet’s core that produces an electrical current. On Earth, the dynamo is what makes compass needles point north. In a paper published in the journal Science Advances, a team of researchers from Canada, the United States and [...]




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Drinking coffee appears to cause epigenetic changes to your DNA

Coffee has been linked to changes on our DNA that affect how active certain genes are. The finding may help explain some of coffee's touted health benefits




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Gears Tactics Review

A Gears of War tactics game? What will they think of next?




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NASA’s Biggest Space Launch in Years Is Coming Up — But It Wants You to Stay Home to Watch

Top officials warned the public against traveling to Florida for the May 27 launch of two NASA astronauts aboard a SpaceX rocket to the International Space Station




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'Weird' exoplanet 800 light-years from Earth has yellow skies and iron rain

Researchers have found the weird exoplanet WASP-79b, nearly 800 light-years from Earth, does not have a blue sky as our planet does. Instead, its skies are yellow.




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Baumhammers still on death row 20 years after killing spree

GREENSBURG, Pa. (AP) - On a cloudy Friday afternoon 20 years ago Tuesday, an unemployed immigration lawyer went on a killing spree. It started next door to his parents’ Mt. Lebanon home, where he killed his Jewish neighbor. He went on to shoot five more people, all ethnic or racial ...




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'Please don't come': calls to close US national parks over virus fears

More than half the National Park Service’s unit remain open but local police and health officials are urging people to stay away

As mild temperatures and spring blooms emerged in southern Utah this past weekend, so did the tourists. At Capitol Reef national park, the trailhead parking lot was full of cars bearing plates from states such as California, Washington, Colorado and Georgia, all Covid-19 hotspots. The hikers were either oblivious to or ignoring the plea from the local sheriff’s office that outsiders stay away.

“While we would normally welcome visitors to enjoy the beauty of Wayne county, we really don’t want visitors during the Covid-19 pandemic,” stated a 3 April post on the sheriff’s Facebook page. Wayne county, where Capitol Reef is located, has 2,600 residents and little in the way of healthcare services. “If you don’t live here, please don’t come here.”

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