Dude you were the best dog ever and I feel sad that we didn't tell you this every day. Yes, you drove us nuts by stealing the cats food and sleeping on

Sage Today I sit alone and cry, Without you by my side. Of all the times I've said goodbye, This one made me cry. If there was anything I could have done,

Jason: It's been one month now since you have gone to Rainbow Bridge. Jason your love was unconditional. You have left my life, but you will never leave

Pixie, you came to us beaten, starved, scared and lonely. No one wanted to take on a rescue Staffordshire Bull Terrier, but we did as company for our

I lost my beloved cat Gemma, seven months ago and when I think about her, I can smile a little. I can now think of the happy times and not that dreadful

The first time we saw Buddy he was walking across the grave of one of our beloved cats, Harley, who had just passed away while we were on vacation. This

Saffron, you were the most perfect being that I could ever envision. You were my sunshine. I miss you beyond words, my little Spoopa Roopa. How can we

Hey Jason! Just checking to see how you are doing at Rainbow Bridge? Hope you are making friends and being a good boy! I missed you so much my baby,

I find it hard to express my feelings, And say how much you meant to us, This poem is just another poor attempt, I’m being such a wuss! I can’t remember

Jess came to me in June 1999 as a birthday gift. She was beautiful white with some brown and black. She was the best birthday present that I ever got or

My Sweet Toby. You were only with us for a short time and was just 15 days shy of 5 months. Why the door had to open when it did, why you ran into the

13 years ago I found out that I had breast cancer. I asked my husband if I could get a dog for comfort. No he said. I started praying for comfort.

Dear Shim Shim, I hate this month, it's so miserable and even more so cos you passed on Halloween eve. I remember it all so vividly, your loss and Zeusy's

Ivy came into my life on December 22, 2012. She was the most beautiful little creature I had ever seen and I knew instantly that she was supposed to be

I lost my Taz April 20th. He was my best friend and companion. He looked at me with so much love. My children and grandchildren live so far away. He

Khan-li my darling boy you were and always will be the Apple of my Eye, The Love Of My Life My Heart and all that is wonderful. The memories I have of

Pepper was not my dog at first, she was given to me when she was a year old. She suffered horrible abuse for the first year of her life, when I got her

2 days ago I lost my best friend. Nine years ago you saved my life and stole my heart. You brought me happiness at my lowest point and gave me reason to

My darling, all of Mama's love. You have gone leaving a void in my life. I still hear you sigh, and the patter of your feet up the steps, and the sound

In the past year I had to put one dog to sleep. I adopted her when she was only 4. When we first got her she had a lot of health problems which got taken

To my beautiful little girl Sassy, I hope wherever you are you are happy and well. I look at your photos that are all around the house and wish you were

Hi my baby girl, How are you? Are you playing and having a good time? Are you staying close to Rufus? I hope you're happy and have all kinds of new friends

Hi my big guy, How are you are you having fun? Are you playing and have you made new friends? Are you keeping an eye on Diana? I hope you are happy and

Seizures often herald the clinical appearance of gliomas or appear at later stages. Dissecting their precise evolution and cellular pathogenesis in brain malignancies could inform the development of staged therapies for these highly pharmaco-resistant epilepsies. Studies in immunodeficient xenograft models have identified local interneuron loss and excess glial glutamate release as chief contributors to network disinhibition, but how hyperexcitability in the peritumoral microenvironment evolves in an immunocompetent brain is unclear. We generated gliomas in WT mice via in utero deletion of key tumor suppressor genes and serially monitored cortical epileptogenesis during tumor infiltration with in vivo electrophysiology and GCAMP7 calcium imaging, revealing a reproducible progression from hyperexcitability to convulsive seizures. Long before seizures, coincident with loss of inhibitory cells and their protective scaffolding, gain of glial glutamate antiporter xCT expression, and reactive astrocytosis, we detected local Iba1+ microglial inflammation that intensified and later extended far beyond tumor boundaries. Hitherto unrecognized episodes of cortical spreading depolarization that arose frequently from the peritumoral region may provide a mechanism for transient neurological deficits. Early blockade of glial xCT activity inhibited later seizures, and genomic reduction of host brain excitability by deleting MapT suppressed molecular markers of epileptogenesis and seizures. Our studies confirmed xenograft tumor–driven pathobiology and revealed early and late components of tumor-related epileptogenesis in a genetically tractable, immunocompetent mouse model of glioma, allowing the complex dissection of tumor versus host pathogenic seizure mechanisms.

Accountants CPA Hartford Connecticut LLC:  This is a rush transcript for April 26, 2015. It may contain errors. GEORGE STEPHANOPOULOS, HOST: And the author of “Clinton Clash,” Peter Schweizer, joins us now. Thank you for joining us this morning, Peter. … Continue reading →

IBM today announced that it is extending the annual Smarter Cities Challenge, a worldwide, highly competitive grant program that provides pro bono consulting to help cities improve the critical services they provide to their citizens.

IBM Research scientists have achieved a new world record in tape storage – their fifth since 2006. The new record of 201 Gb/in2 (gigabits per square inch) in areal density was achieved on a prototype sputtered magnetic tape developed by Sony Storage Media Solutions. The scientists presented the achievement today at the 28th Magnetic Recording Conference (TMRC 2017) here.

Pets at Home, the UK’s leading pet specialist retailer and IBM today announced the launch of Sales Assist, an IBM MobileFirst for iOS app for iPad which will be used across 440 stores nationwide to make it easier and simpler for customers to purchase the products they need.

Lingmo’s Translate One2One uses IBM Watson Artificial Intelligence technology to translate in natural language.

A Peter MacCallum Cancer Centre study has demonstrated the potential for artificial intelligence to help reduce the time for clinicians to match lung cancer patients to relevant clinical trials.

IBM (NYSE: IBM) today announced it will establish a Natural Resources Solution Centre (NRSC) in Perth to help mining, LNG and petroleum companies accelerate the development and adoption of innovative technologies and business strategies.

Free Tutorial! Since many people are bored at home and looking to add to their skillset, I have just released my best tutorial for free and it already has just over $92,000 worth of downloads – awesome! People seem to love it and thank you for the great feedback. I’ll keep it free as long […]

peterboyden:

americanapparel:

Source: idea.ltd

BOYDENS Magazine

 A lovely thing happened to me this month. The Writer's Guild of Great Britain gave me their Outstanding Contribution to Writing Award.

Mondo Duplantis of Sweden and Renaud Lavillenie of France tied for the gold medal Sunday during a men's pole vault competition held in their own backyards.

Preventivní opatření proti nákaze covid-19 zasáhla jak firmy všech velikostí, tak živnostníky. Jenže právě osoby samostatně výdělečně činné patří podle vlády ke skupinám, které krize vyvolaná pandemií nejvíce ohrozí. Zejména pak ty, kteří mají živnost jako hlavní zdroj příjmů a nemají ji jako přivýdělek k zaměstnání. Jak je stát podpoří?

Finanční znalosti Čechů se začínají zlepšovat. V indexu finanční gramotnosti, který každoročně měří Česká bankovní asociace, dosáhli Češi 61 procentních bodů ze 100. Oproti loňskému roku to je o čtyři body více, což je doposud nejvyšší hodnota za posledních několik let. Problém ale je, že pětina lidí přiznává, že má finanční polštář vytvořený jen na pouhý měsíc.

Histogram: You have to know the past to understand the present by Tomas Petricek, University of Kent

Programs are created through a variety of interactions. A programmer might write some code, run it interactively to check whether it works, use copy and paste, apply a refactoring or choose an item from an auto-complete list. Programming research often forgets about these and represents programs as the resulting text. Consequently, thinking about such interactions is often out of scope. This essay shifts focus from programs to a more interesting question of programming.

We represent programs as lists of interactions such as triggering an auto-complete and choosing an option, declaring a value, introducing a variable or evaluating a piece of code. We explore a number of consequences of this way of thinking about programs. First, if we create functions by writing concrete code using a sample input and applying a refactoring, we do not lose the sample input and can use it later for debugging. Second, if we treat executing code interactively as an interaction and store the results, we can later use this information to give more precise suggestions in auto-complete. Third, by moving away from a textual representation, we can display the same program as text, but also in a view inspired by spreadsheets. Fourth, we can let programmers create programs by directly interacting with live previews as those interactions can be recorded and as a part of program history.

We discuss the key ideas through examples in a simple programming environment for data exploration. Our focus in this essay is more on principles than on providing fine tuned user experience. We keep our environment more explicit, especially when this reveals what is happening behind the scenes. We aim to show that seeing programs as lists of interactions is a powerful change of perspective that can help us build better programming systems with novel features that make programming easier and more accessible. The data exploration environment in this interactive essay may not yet be that, but it gives a glimpse of the future.

The 1996 Ig Nobel Prize for biology was awarded to Anders Barheim and Hogne Sandvik of the University of Bergen, Norway, for their tasty and tasteful report, “Effect of Ale, Garlic, and Soured Cream on the Appetite of Leeches.” Recently, Bradley Allff, writing in Atlas Obscura, looked at the role medical leeches sometimes play in medicine in the USA. […]

1. Axed Western Force to rejoin Aussie rugby competition in July  PerthNow
2. New Zealand plotting stunning multi-billion dollar escape from World Rugby  Fox Sports
3. RA to ditch Super Rugby?  RugbyPass
4. Forget the Kiwis, Australian rugby's future is local  Sydney Morning Herald
5. Half of New Zealand Rugby staff face redundancy amid $NZ7m lockdown loss  The Guardian
6. View Full coverage on Google News

Chewy and Miley, both two-year-old Schnauzer dogs, are getting their hair cut at a groomer in Bangkok for the first time since the new coronavirus outbreak began in Thailand in January.

An interview with Peter Macleod, Chief Executive of the Care Inspectorate and Chair of Iriss.

Peter graduated from Robert Gordon University with a degree in social sciences and a qualification in social work and began a career as a social worker in Glasgow in 1987.

In 1996 he joined Renfrewshire council as an area manager, responsible for adult, children’s and criminal justice social work, and in early 2007 was appointed head of children’s services and criminal justice for social work and the community health partnership.

In 2015, he was appointed Renfrewshire’s first director of a new children’s services directorate, bringing together children’s social work, education and criminal justice services.

He sits on the boards of MacMillan Cancer Support TCAT Programme and Scottish Government’s Re-aligning Children’s Services programme.

In his own words, he says, "I am ambitious for social care; I want people in Scotland to experience transformational, world-class care that makes a real and positive difference to their lives."

Transcript of episode

Music Credit: Make your dream a reality by Scott Holmes.

Poor Mayor Pete just can't seem to catch a break on the internet. The presidential candidate from South Bend, Indiana tweeted a photo of himself walking down a hallway on Saturday with the caption, "On my way back to Iowa. It's phase 4. Let's do this." The tweet has been catching a fair amount of flack for appearing to be staged. 

Here are some of Twitter's most amusing reaction memes and tweets!

  Who let the dogs out????? To kick off #NationalPetMonth, we want to remind everyone about pet fire safety. With stay-at-home orders in place in many jurisdictions, we have been made aware of many fire departments responding to fires, then

Claude is among the best bottoms and would certainly be the winner of the cutest dimples award. Given his expertise as a bottom you might be as shocked as we were to find Claude topping Peter. Yet there’s no mistake it is Claude in control using the compliant Peter for his pleasure. See more at... View Article

The post Freshmen: Peter Annaud and Claude Sorel appeared first on QueerClick.

After receiving nearly 500 submissions from around the world, eVolo Magazine has announced the winners of the 2020 Skyscraper Competition. Established in 2006, the annual award recognizes visionary vertical architecture ideas that push the limits of design and technology. First place was awarded to a Chinese team that designed Epidemic Babel, a rapid-deployment healthcare skyscraper concept for mitigating epidemic outbreaks.[...]

By Isaac Cabe  Published: May 08th, 2020