The present invention relates to novel muteins derived from human lipocalin 2 (hNGAL) and related proteins that bind a given non-natural ligand with detectable affinity. The invention also related to corresponding nucleic acid molecules encoding such a mutein and to a method for their generation. The invention further relates to a method for producing such a mutein. Furthermore, the invention is directed to a pharmaceutical composition comprising such a lipocalin mutein as well as to various uses of the mutein.

Methods, systems, and computer readable media for measuring multicast latency are disclosed. According to one method, the method includes emulating one or more Internet protocol television (IPTV) user devices by generating channel leave and join requests. The method further includes monitoring network responses to the channel leave and join requests and calculating, during a cycle of channel leave and join requests for a user device and prior to repeating the cycle, at least one metric of latency associated with the channel leave and join requests.

A heterocyclic compound represented by Formula 1 or Formula 2 below and an organic light-emitting device including the heterocyclic compound: wherein X1, X2, and R1 through R16 are defined as in the specification.

An optical film has a cellulose acylate film base material containing cellulose acylate and a plurality of sugar ester compounds having different ester substitution degrees in which an average ester substitution degree of the plurality of sugar ester compounds is from 60 to 94%, and an antistatic hardcoat layer formed from a coating composition containing at least an organic antistatic agent and a curable compound having a (meth)acryloyl group in a molecule of the curable compound.

Provided is a zinc-plated steel sheet for hot pressing having outstanding surface characteristics, comprising: a steel foundation plate comprising a metal surface diffusion layer of which the Gibbs free energy reduction per mole of oxygen during oxidation is less than that of Cr; an aluminum-rich layer containing at least 30 wt. % of aluminum formed on the surface diffusion layer, and a zinc plating layer formed on the aluminum-rich layer. In this way, a metal having a low affinity for oxygen is coated to an effective thickness prior to annealing and thus the creation of annealing oxides at the surface of the steel sheet is suppressed and a uniform zinc plating layer is formed, and alloying of the zinc plating layer is promoted during press-processing heat treatment. Cracking in the steel foundation plate during hot press molding is prevented.

Compositions and methods for the treatment of asthma and inflammatory ocular disorders are disclosed.

There is provided a disk drive apparatus including a first chassis unit that has a pickup base at which an optical pickup and a disk table have been disposed, and a first base chassis to which the pickup base has been attached, and a second chassis unit that has a second base chassis and at which a chucking pulley has been disposed. A first rectifying plate part is provided at the first base chassis. A second rectifying plate part is provided at the second base chassis.

A cleaning system for use in a combine harvester including an auger bed mounted within a frame such that when the combine harvester is laterally inclined from the horizontal, the cleaning system, including the auger bed and a sieve, may be leveled or substantially leveled to a generally horizontal position. The auger bed can include a plurality of augers located side by side with their axes positioned generally longitudinally in the combine harvester.

A work hanging apparatus includes a hanger line continuously conveying hangers each having a hook, a robot that has a hand with which a work having a hole is held and transfers the held work to a hanging location set in the hanger line, a controller controlling a movement of the hand to catch the hook of one of the hangers with the hole of the held work at the hanging location, a hole deviation detector that detects a positional deviation of the hole of the work, an attitude deviation detector that detects an attitudinal deviation of the hanger, and a corrector that corrects the movement of the hand according to the positional and attitudinal deviations.

Systems and methods are disclosed for isolated bands of fractional tracks in data storage devices, particularly devices employing shingled magnetic recording. In one embodiment, a device may comprise a data storage medium including a first data storage area including tracks overlapped in a shingled manner and having a first circumferential portion of a track to store data, a second data storage area, and a guard area disposed between the first data storage area and the second data storage area, the guard area including a second circumferential portion of the track as a partial guard track. In some embodiments, the guard area may include at least one sector in the first circumferential portion of the track, such that at least one sector of the guard area is interposed between data storage sectors of the first data storage area.

A disk drive is disclosed comprising a disk, and a slider comprising a head, where the head comprises a write component electrically insulated from the slider. A bias voltage is applied to the write component, and a current flowing between the write component and the disk is measured, wherein the current is indicative of a fly height of the head.

The invention provides intermediates of the formula: as well as a method of their preparation by reacting a thiol having at least two hydroxyl groups with a mono-unsaturated organic compound in the presence of a base catalyst. A polymerizable urethane acrylate oligomer or urethane methacrylate oligomer is formed by reacting a polyisocyanate with the intermediate. The polymerizable urethane acrylate oligomer or urethane methacrylate is blended with a polymerization initiator to form a composition which is useful in such applications as adhesives.

A system for converting an existing traffic intersection into an intersection having a roundabout traffic control feature includes a center island framework, one or more splitter island frameworks, and one or more diverter frameworks. The frameworks are secured to the road surface, and fill material is added to free spaces defined in the frameworks to thereby form a center island, one or more splitter islands, and one or more diverters. The system allows a roundabout to be implemented into an existing intersection on a temporary or semi-permanent basis, in a minimal amount of time and without requiring significant construction at the site of the intersection.

A mobile wireless communications device may include a portable housing, a circuit board carried by the portable housing, a wireless communications circuit carried by the circuit board, and an audio circuit carried by the circuit board. The mobile wireless communications device may further include an antenna assembly including an antenna carrier frame coupled to the circuit board and defining a cavity therein, and an antenna element carried on the antenna carrier frame and having a plurality of spaced apart signal feed points coupled to the wireless communications circuit. In addition, an audio transducer may be carried within the cavity of the antenna carrier frame and coupled to the audio circuit.

A wireless communication device is configured for performing uplink transmission power control. The wireless communication device includes a processor and instructions stored in memory. The wireless communication device performs uplink transmission power control for multiple regulated frequency bands or component carriers. The wireless communication device determines a total transmission power for at least one component carrier and allocates transmission power to at least one antenna.

Embodiments of the invention disclose a backlight unit, including: a light guide plate, a light source member, a reflection film, wherein: the light guide plate (LGP) includes a light incident side, a light emission side and a bottom side opposite to the light emission side, the light guide plate is for emitting light entered from the light incident side through the light emission side; the light source member is disposed on the light incident side of the LGP and light emitted by the light source member enters the LGP through the light incident side of the LGP; the reflection film is at least disposed on the bottom side of the LGP and is for reflecting light back into the LGP; wherein a reflection structure is disposed on the bottom side of the LGP and a microstructure is disposed on the light emission side of the LGP.

A backlight assembly includes a first light source unit including n light emitting members; and a light guide plate including a first side adjacent to the first light source unit, and a first groove adjacent to a first end of the first side.

The present invention is directed to implantable devices for stabilizing or fusing bone structures within the spine. More specifically, the present invention is a spinal plate assembly that includes an automatic mechanism for blocking the pathway of a bone fastener once inserted to prevent unwanted backwards migration of the bone screw.

An anterior cervical plate system is provided. The cervical plate includes a retention ring with a deflectable flange that is upwardly spaced from the top surface of the ring and configured to prevent an inserted bone fastener from backing out of the plate. The plate includes a locking pin having a camming surface and a blocking surface. When the camming surface is moved into position adjacent to the flange, the flange is free to flex out of the way of a bone screw being inserted into or removed from the plate. When the blocking surface is positioned adjacent to the flange, outward deflection of the flange is prevented to retain the bone screw inside the plate. The locking pin is rotated through a camming surface to bring a blocking surface against the flange deflecting the flange onto the head of the bone screw.

A system apparatus and method for protecting information are provided. Embodiments of the invention may detect inactivity related to a computing device. Information and encryption key may be removed from a memory. Subsequent activity may be detected. An authentication procedure may be performed, and, contingent on authenticating a relevant entity, a master key may be generated and installed in a memory.

In accordance with this invention a binder composition for treating particulate material to form a solid aggregate matrix is prepared by providing a urea formaldehyde precondensate; a polar solvent; additional urea; an acid or salt thereof, the acid or salt thereof being selected such as to render the pH of the binder composition to a value from 2.0 to 5.3; providing a sugar; providing a binding promoter for enhancing the binding between the binder composition and the particulate material; and mixing the above so as to form a binder composition. The binder composition is mixed with particulate material and allowed to set into a solid aggregate matrix over a period of longer than 30 minutes from being mixed with the said particulate material.

Discrete micro and nanoscale particles are formed in predetermined shapes and sizes and predetermined size dispersions. The particles can also be attached to a film to form arrays of particles on a film. The particles are formed from molding techniques that can include high throughput and continuous particle molding.

The object of the invention is to provide a method and an apparatus that allow production of metal plate chip resistors having a relatively low resistance with high accuracy and yield through simple process. The object is achieved by apparatus for manufacturing metal plate chip resistors including cutting mold for cutting intermediate product strip transversely to obtain worked product chip, ohm meter for measuring the resistance of the worked product chip, control device having a calculating part for performing a calculation using the resistance measured by the ohm meter to work out a width in which the strip is to be cut transversely so as to obtain a worked product chip of a desired resistance, and cutting width adjustor for making an adjustment so that the strip is to be cut transversely in the width obtained from the calculating part.

An articulated work holder for a fractional dimensioned, performance vehicle including a base member and first, second and third, support arms having multiple degrees of rotational movement and a vise member carrying vehicle engagement pads for supporting a fractional dimensioned, performance vehicle between the vise engagement pads.

In some aspects, an unloading device for a pipe processing system includes a depositing carriage having a depositing surface for depositing a pipe during and/or after a pipe processing operation, the depositing carriage being configured to move in a longitudinal direction of the pipe, and a supporting carriage having a supporting member for the pipe, the supporting member having a wall for radially supporting the pipe, and the supporting carriage being configured to move in a longitudinal direction of the pipe, where the depositing surface of the depositing carriage and/or the supporting member of the supporting carriage is configured to move in at least one other direction in addition to the longitudinal direction of the pipe so that the depositing carriage and the supporting carriage can be at least partially moved past each other along the longitudinal direction of the pipe.

This invention relates to the field of preparation technology of optical pH sensor by co-intercalated fluorescein and 1-heptanesulfonic acid sodium into layered double hydroxide. The sensor is composed by conductive materials and the surface LDH films by co-interacted FLU and HES. The synthesis method is: first: synthesis of LDH colloid suspension, subsequently, the FLU and HES co-intercalated LDH colloid solution was prepared following the ion-exchange method, then the thin film of FLU-HES/LDH was spreaded on the surface of the conductive material by electrophoretic deposition, and the oriental pH sensor was synthesized. The advantages of the present invention is: first, the LDH matrix provides chromophore molecules with a confined and stable environment; the novel electrophoretic deposition strategy in this work provides a method for precise control of thickness (ranging from nanometers to micrometers), and the oriental pH sensor show good pH responsive.

A molecularly imprinted polymer (MIP) sensor including a substrate, two or more electrodes, a conductive layer applied to the substrate and a molecularly imprinted polymer layer applied to the conductive layer is disclosed herein The MIP sensor may form part of an MIP sensor system that can be used to detect and quantify target molecules.

The invention describes biomarkers which can be used to predict the likelihood that an individual will develop Diabetes. The biomarkers can also be used to screen large groups in order to identify individuals at risk of developing Diabetes.

The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.

A two step lateral flow assay method for identifying IgE antibodies in a sample comprises applying a sample to a sample port of a device, wherein the device is adapted to deliver the sample to a lateral flow matrix having a plurality of IgE antigen species immobilized at respective positions at a first location; allowing the sample to travel along the lateral flow matrix through the immobilized plurality of IgE antigen species to a second location downstream of the first location; and, after a predetermined period of time, applying liquid buffer to the lateral flow matrix to mobilize labeled reagent which is adapted to bind anti-IgE antibody and which is dried on the lateral flow matrix at a location upstream of the sample port delivery of the sample to the lateral flow matrix, and allowing labeled reagent mobilized by the liquid buffer to travel along the lateral flow matrix through the immobilized plurality of IgE antigen species and bind with any IgE antibody bound to the immobilized IgE antigen species, and to travel to a second location downstream of the first location where the mobilized labeled reagent causes a visible change to occur at the second location.

Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

An exemplary surgical apparatus may include a shaft defining a lumen therein; articulation bands extending through and slidable generally longitudinally within the lumen of the shaft; an end effector affixed to the articulation bands; and generally annular segments positioned about the articulation bands along at least a portion of the length of the articulation bands to define an articulated region, where the segments laterally constrain the articulation bands.

Barium, strontium, tantalum and lanthanum precursor compositions useful for atomic layer deposition (ALD) and chemical vapor deposition (CVD) of titanate thin films. The precursors have the formula M(Cp)2, wherein M is strontium, barium, tantalum or lanthanum, and Cp is cyclopentadienyl, of the formula (I), wherein each of R1-R5 is the same as or different from one another, with each being independently selected from among hydrogen, C1-C12 alkyl, C1-C12 amino, C6-C10 aryl, C1-C12 alkoxy, C3-C6 alkylsilyl, C2-C12 alkenyl, R1R2R3NNR3, wherein R1, R2 and R3 may be the same as or different from one another and each is independently selected from hydrogen and C1-C6 alkyl, and pendant ligands including functional group(s) providing further coordination to the metal center M. The precursors of the above formula are useful to achieve uniform coating of high dielectric constant materials in the manufacture of flash memory and other microelectronic devices.

Barium, strontium, tantalum and lanthanum precursor compositions useful for atomic layer deposition (ALD) and chemical vapor deposition (CVD) of titanate thin films. The precursors have the formula M(Cp)2, wherein M is strontium, barium, tantalum or lanthanum, and Cp is cyclopentadienyl, of the formula wherein each of R1-R5 is the same as or different from one another, with each being independently selected from among hydrogen, C1-C12 alkyl, C1-C12 amino, C6-C10 aryl, C1-C12 alkoxy, C3-C6 alkylsilyl, C2-C12 alkenyl, R1R2R3NNR3, wherein R1, R2 and R3 may be the same as or different from one another and each is independently selected from hydrogen and C1-C6 alkyl, and pendant ligands including functional group(s) providing further coordination to the metal center M. The precursors of the above formula are useful to achieve uniform coating of high dielectric constant materials in the manufacture of flash memory and other microelectronic devices.

Barium, strontium, tantalum and lanthanum precursor compositions useful for atomic layer deposition (ALD) and chemical vapor deposition (CVD) of titanate thin films. The precursors have the formula M(Cp)2, wherein M is strontium, barium, tantalum or lanthanum, and Cp is cyclopentadienyl, of the formula wherein each of R1-R5 is the same as or different from one another, with each being independently selected from among hydrogen, C1-C12 alkyl, C1-C12 amino, C6-C10 aryl, C1-C12 alkoxy, C3-C6 alkylsilyl, C2-C12 alkenyl, R1R2R3NNR3, wherein R1, R2 and R3 may be the same as or different from one another and each is independently selected from hydrogen and C1-C6 alkyl, and pendant ligands including functional group(s) providing further coordination to the metal center M. The precursors of the above formula are useful to achieve uniform coating of high dielectric constant materials in the manufacture of flash memory and other microelectronic devices.

A sequential punch press includes an upper die (10), a lower die (90), and an adjusting device (60) in the upper die. The upper die sequentially includes a punch set (20), a punch pad (30), a punch holder (40), and a stripper (50). A punch (70) is vertically and movably secured in the punch holder and received in the stripper. The adjusting device includes first and second sliding plates (64, 66) respectively having protrusions (65b, 67b), a piston cylinder (68) having a piston rod (682) fixedly connected with the first sliding plate, and a programmable controller for causing the piston rod to slidingly move the first sliding plate. When the first protrusions opposingly abut the second protrusions, the punch can extend beyond the stripper to punch a workpiece. When the first protrusions do not opposingly abut the second protrusions, the punch cannot extend beyond the stripper to punch the workpiece.

An apparatus for penetrating a cover over a multi-well sample plate containing at least one individual sample well includes a cutting head, a cutter extending from the cutting head, and a robot. The cutting head is connected to the robot wherein the robot moves the cutting head and cutter so that the cutter penetrates the cover over the multi-well sample plate providing access to the individual sample well. When the cutting head is moved downward the foil is pierced by the cutter that splits, opens, and folds the foil inward toward the well. The well is then open for sample aspiration but has been protected from cross contamination.

A punch assembly for a turret punch press having a two piece reciprocally movable punch member that has a punch point insert removably attached to a punch driver that allows replacement of the punch point insert without the need to extract the punch member from its punch guide. A locking assembly having four vertical guideways containing slider strips for coupling the punch point insert to the punch driver ensures precision registration of the punch point insert with its driver.

The present invention provides stabilized oil-in-water emulsions with an extended range of chemical, thermal and/or mechanical stabilities, and method(s) for their preparation. Such preparations provide an environmentally-protective biopolymer component exhibiting improved adherence to the dispersed phase, reducing or eliminating dissociation therefrom under such conditions, for use in the context of a range of food, pharmaceutical, personal care, health care, cosmetic and other end-use applications.

An image sensing and printing digital camera device includes a housing defining a slot for receiving a printed instruction card having printed thereon an array of dots representing a programming script, the housing further storing therein a roll of print media; an area image sensor for sensing an image and generating pixel data representing the image; a linear image sensor for scanning the array of dots on the card and converting the array of dots into a data signal; a microcontroller provided in the housing, the microcontroller for decoding the data signal into the programming script and applying the programming script on the pixel data; and a printing mechanism for printing the pixel data, having applied thereto the programming script, on the roll of print media. The microcontroller integrates on a single chip a VLIW processor, a printhead interface, and an output buffer effecting communication between the VLIW processor and the printhead interface.

This invention relates to hand manipulated toy construction equipment such as backhoes, trucks, etc. In one embodiment, the truck body is hollow at one end so that the truck may be manipulated by inserting one's arm into the truck body and grasping and manipulating a transverse dowel handle. Spring-loaded means are provided within the truck body and are coupled to the dumper to control the motion of the equipment. A sound module is also provided to simulate construction sounds.

An interposer (support substrate) for an opto-electronic assembly is formed to include a thermally-isolated region where temperature-sensitive devices (such as, for example, laser diodes) may be positioned and operate independent of temperature fluctuations in other areas of the assembly. The thermal isolation is achieved by forming a boundary of dielectric material through the thickness of the interposer, the periphery of the dielectric defining the boundary between the thermally isolated region and the remainder of the assembly. A thermo-electric cooler can be used in conjunction with the temperature-sensitive device(s) to stabilize the operation of these devices.

A device including one or more layers with lateral regions configured to facilitate the transmission of radiation through the layer and lateral regions configured to facilitate current flow through the layer is provided. The layer can comprise a short period superlattice, which includes barriers alternating with wells. In this case, the barriers can include both transparent regions, which are configured to reduce an amount of radiation that is absorbed in the layer, and higher conductive regions, which are configured to keep the voltage drop across the layer within a desired range.

Methods for creating customized children's storybooks with fingerprint art using fingerprint-ready templates stored in association with a software application on a desktop computer, a tablet computer, or a smart phone. The methods include the use of preconfigured templates and prompted discussions that elicit responses from the child to create text for the storybook. The text may be generated by speech recognition software processing digital audio recordings of the child's responses. A digital image of the child's fingerprint is acquired and the fingerprint image and/or the storybook scenes are scaled to fit each other. Fingerprint-ready image templates are used to facilitate the creation of fingerprint art. A completed page image is formed by digitally inserting a fingerprint into the fingerprint-shaped area, and if desired, coloring the image or drawing a scene around the image. When the scenes are completed the software application compiles the book pages and prints the same.

A manufacturing method and device for supporting conductors. Using a non-metallic insulating material extending beyond one or both parallel legs of a staple the thumb and forefinger may grip this extension while the staple is being driven into a supporting structure. This finger grip allows for a small, insulated staple to be held with increased safety to thumb and forefinger during penetration of staple into support.

To suppress malfunctions in a shift register circuit. A shift register having a plurality of flip-flop circuits is provided. The flip-flop circuit includes a transistor 11, a transistor 12, a transistor 13, a transistor 14, and a transistor 15. When the transistor 13 or the transistor 14 is turned on in a non-selection period, the potential of a node A is set, so that the node A is prevented from entering into a floating state.

A bilateral cargo strap system is provided as a means of securing a variety of different cargo within a storage area. The bilateral cargo strap system utilizes a combination of elastic straps with perpendicularly positioned stabilizing rods to improve retention of a variety of cargo within a storage area. The elastic straps extend over the retained cargo and are used as the means of engaging mounting features within the storage area. The stabilizing rods effectively distribute the tension force of the elastic straps over the retained cargo securing it in place within the storage space. The bilateral cargo strap system is versatile and may be used to secure a wide variety of cargo including, but not limited to, kayaks, coolers, bicycles, lumber, and construction equipment.

A bull ring for a vehicle comprises a top plate coupled to a rotating plate having a tie-down. Two opposing rail flanges extend from the rotating plate and a fastener selectively couples the rotating plate in a securing position relative to the top plate. The rail flanges extend beyond an outer edge of the top plate to define a clamping region with the top plate.

A method for quickly calibrating a memory interface circuit from time to time in conjunction with operation of a functional circuit is described. The method uses controlling the memory interface circuit with respect to read data capture for byte lanes, including controlling CAS latency compensation for the byte lanes. In the method control settings for controlling CAS latency compensation are determined and set according to a dynamic calibration procedure performed from time to time in conjunction with functional operation of a circuit system containing one or more memory devices connected to the memory interface circuit. In the method, determining and setting the control settings for controlling CAS latency compensation is performed independently and parallely in each of the byte lanes.

A III-N device is described with a III-N material layer, an insulator layer on a surface of the III-N material layer, an etch stop layer on an opposite side of the insulator layer from the III-N material layer, and an electrode defining layer on an opposite side of the etch stop layer from the insulator layer. A recess is formed in the electrode defining layer. An electrode is formed in the recess. The insulator can have a precisely controlled thickness, particularly between the electrode and III-N material layer.