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Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer

J. Mater. Chem. B, 2020, 8,3789-3800
DOI: 10.1039/D0TB00046A, Paper
Shih-Hong Chen, Te-I Liu, Cheng-Lin Chuang, Hsin-Hung Chen, Wen-Hsuan Chiang, Hsin-Cheng Chiu
Through hierarchically targeting bone matrix and tumor cells, PTX-carrying ALN/FA-nanoparticles substantially accumulate in bone metastases and improve mice survival rate.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Calcium alendronate-coated composite scaffolds promote osteogenesis of ADSCs via integrin and FAK/ERK signalling pathways

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00571A, Paper
Lei Liu, Xianling Gao, Xiaoyu Li, Guanglin Zhu, Nanying Li, Xuetao Shi, Yingjun Wang
Bioceramic-biopolymer composites have been used extensively as bone tissue engineering scaffolds due to their bioactive properties. However, composite scaffolds are insufficient in inducing osteogenic differentiation of stem cells. In this...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The ethics of journalism : individual, institutional and cultural influences / edited by Wendy N. Wyatt




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Post-1990 documentary : reconfiguring independence / edited by Camille Deprez and Judith Pernin




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Drug-drug interaction primer : a compendium of case vignettes for the practicing clinician / by Neil B. Sandson ; contributors, Scott C. Armstrong, Kelly L. Cozza, Jessica R. Oesterheld

Sandson, Neil B., 1965-




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Rang and Dale's pharmacology / H.P. Rang, J.M. Ritter, R.J. Flower, G. Henderson

Rang, H. P., author




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Therapeutic medicinal plants from lab to the market / editors: Marta Cristina Teixeira Duarte, Mahendra Rai




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The health effects of cannabis and cannabinoids : the current state of evidence and recommendations for research / Committee on the Health Effects of Marijuana: an Evidence Review and Research Agenda, Board on Population Health and Public Health Practice,

National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on the Health Effects of Marijuana: an Evidence Review and Research Agenda, author




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Empire ascendant / Kameron Hurley

Hurley, Kameron, author




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Thomas' calculus : early transcendentals / based on the original work by George B. Thomas, Jr. ; as revised by Maurice D. Weir, Joel Hass ; with the assistance of Christopher Heil ; SI conversion by Antonio Behn

Thomas, George B.,, Jr. (George Brinton), 1914-2006




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Thomas' calculus : early transcendentals / based on the original work by George B. Thomas, Jr., Massachusetts Institute of Technology ; as revised by Joel Hass, University of California, Davis, Christopher Heil, Georgia Institute of Technology, Mauric

Hass, Joel




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College algebra with intermediate algebra : a blended course / Judith A. Beecher, Judith A. Penna, Barbara L. Johnson, Ivy Tech Community College of Indiana, Marvin L. Bittinger, Indiana University, Purdue University, Indianapolis

Beecher, Judith A




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Calculus : early transcendentals / James Stewart McMaster University and University of Toronto

Stewart, James, 1941- author




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Statistics for engineering and the sciences / William M. Mendenhall, Terry L. Sincich

Mendenhall, William, author




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Statistics for engineering and the sciences : student solutions manual / William M. Mendenall, Terry L. Sincich, Nancy S. Boudreau

Mendenhall, William, author




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A second course in statistics : regression analysis / William Mendenhall, Terry Sincich

Mendenhall, William, author




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University calculus : early transcendentals / Joel Hass (University of California, Davis), Maurice D. Weir (Naval Postgraduate School), George B. Thomas, Jr. (Massachusetts Institute of Technology) ; with the assistance of Christopher Heil (Georgia Intitu

Hass, Joel, author




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Numerical linear algebra : an introduction / Holger Wendland

Wendland, Holger, 1968- author




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Linear mixed models : a practical guide using statistical software / Brady T. West, Kathleen B. Welch, Andrzej T. Gałecki, University of Michigan, Ann Arbor, USA ; with contributions from Brenda W. Gillespie

West, Brady T




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University calculus : early transcendentals, single variable

Hass, Joel, author




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Emerging trends, threats, and opportunities in international marketing : what executives need to know / Michael R. Czinkota, Ilkka A. Ronkainen, and Masaaki Kotabe ... [et al.]




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Digital sense : the common sense approach to effectively blending social business strategy, marketing technology, and customer experience / Travis Wright, Chris J. Snook

Wright, Travis, author




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Facebook to send Amber Alerts to users news feeds

The national Amber Alert system for missing children -- already on highway billboards, mobile phones and the Internet -- is extending its reach to Facebook, the globes biggest social site.

The Menlo Park social media giant announced Tuesday that it is partnering with the National Center for Missing and Exploited Children to send geographically targeted Amber Alerts to the members of the U.S. Facebook community.

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8 Social-Media Sins That Are Sure to Get You Unfriended and Unfollowed

According to a recent social-media engagement study, Americans now spend more time on social media than any other Internet activity, including email. Social media is not going anywhere and businesses, small and large, are now recognizing their online presence is an essential part of their marketing strategy. Eight out of 10 small to medium-sized businesses now use social media to drive growth for their business, and three out of five say they have gained new customers through social media marketing.

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Social Media Makes You Spend More

When I ran a Facebook ad recently for a nonprofit where I volunteer, I was surprised how specific you could get in targeting potential customers. If I wanted to advertise the event I was promoting to women between the ages of 24 and 26 in my city who were unmarried and educated, who watched Girls, owned a dog and liked designer purses — I could do that.

Being able to target ads to a specific market can help a seller reach the people who want or need their products and services. Unfortunately, that means buyers may also be encouraged to spend more than they should if they are not mindful.

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8 Social Media Trends

Long gone are the days when social media was a giant question mark in terms of measurement and ROI.

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The 15 Social Media Trends that Defined a Generation

Over the past few years, social media has given rise to a number of crazes that have quickly spread across the web; with the likes of Twitter and Facebook, a trend started in Devon can reach Delaware in a matter of minutes. In the past 5 years, social media trends have got bigger and bigger, and in some cases wackier and wackier.

From the more absurd trends like Batmanning and Cinnamon Challenge, to those with an underlying charitable cause like the Ice Bucket Challenge, social media trends spread like wildfire. Chances are you will have had at least a handful of trends pop up on your social media feeds over the years.

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6 Social Media Marketing Trends for 2015

As we look to 2015, what social media marketing trends are likely to develop? Here are six that online retailers should monitor.

1. Niche Social Networks Will Emerge

Mainstream social networks like Facebook, Twitter, and LinkedIn will face challenges from lesser-known upstarts in 2015. One example is Ello, an ad-free social platform still in beta that has received a great deal of attention among those that follow social media developments.

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4 Key Social Media Marketing Trends To Lead The Game in 2016

The same laws of attraction have never governed the social media marketing scene for too long.

Just as one Tweet changes another, so does user preferences when it comes to consuming online content. New social media rise and fall quickly and this year SnapChat and Periscope already shown a great influence on the marketing landscape. With new players entering the field and old companies rushing to introduce new features and innovations, the rules of social media play hardly ever stay the same.

In 2016 we should expect to see new exciting trends and changes in the social scene and here are the top 4.

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This Chrome Extension Replaces Facebooks Trending Topics with any RSS feed

Are you tired of Facebooks trending section in your News Feed? Celebrity news getting annoying? Would you rather have legitimate news? Introducing Fluffblocker.

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This Chrome extension replaces Facebooks trending topics with any RSS feed

Are you tired of Facebooks trending section in your News Feed? Celebrity news getting annoying? Would you rather have legitimate news? Introducing Fluffblocker.

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Social Media Trends to Watch

Influencer Marketing

According to the latest Nielson study, over 90% of consumers trust recommendations from friends and family. We have slapped a fancy name on it, but at the end of the day, this is what influencer marketing really is: getting products into the hands of people whom others trust. Peer recommendations have the power to sway buyers and inspire purchase decisions, not because they have a zillion followers or have perfect lips, but because they are reliable, personable sources we believe.




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10 Social Media Posts That Deserve a Place in Your Content Calendar

From solo entrepreneurs to Main Street businesses and multinational brands, marketers at all levels struggle with finding new ways to keep their followers’ attention. I often see brands fall into the habit of posting repetitive types of content. This usually leads to a sharp drop in engagement.

Your followers need variety. If you don’t mix it up a little bit, you’ll risk losing their attention permanently. To inject some diversity, start working these 10 social post structures into your daily content calendar.

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Amazons Alexa can tell you what's trending on Twitter

A report yesterday revealed that Amazon might open up its Alexa ecosystem to allow push notifications, so that it could interrupt to warn you about a traffic jam, for instance.

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Celebrities endorsement earnings on social media

Since January, more than 200,000 posts per month on Instagram, a picture-sharing app owned by Facebook, have been tagged with #ad,  #sp or #sponsored, according to Captiv8, an analytics platform that connects brands to social media influencers. Hiring such influencers allows companies to reach a vast network of potential customers: Mr Ronaldo has a combined following of 240m people across Facebook, Instagram and Twitter.

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A really simple guide to really simple syndication (RSS)XXRead more: http://www.digitaltrends.com/computing/how-to-use-rss/#ixzz4ObPKdolR XFollow us: @digitaltrends on Twitter | digitaltrendsftw on Facebook

The Internet is a big place. Really big. With more than a billion existing pages and thousands more being created each day, there is a wealth of great sites offering fantastic content free of charge. But with such a massive torrent of media being produced each and every day, it can often be tough to keep up with all your favorite websites. So, how do we alleviate this problem? Easy. Here’s a really simple explanation of Really Simple Syndication (RSS).

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6 Social Media Trends to Prepare for in 2018

2018 is only four months away, and brands have to prepare to take advantage of the opportunities social media presents -- or their competitors will.

When it comes to reaching audiences, effectively distributing your content, and building a following around your brand, social media offers a wealth of possibilities. It's where your audiences already live and engage with content, which makes it a convenient platform for brands. Its built-in analytics allow you to track and improve your efforts over time. Plus, all the free social-media tools make it easy to use and maintain an active presence.

As you look ahead to 2018 and begin planning for ways to strengthen your social strategy, it is important to keep a pulse on trends.

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5 Social Media Trends That Will Have Maximum Impact in 2018

With more and more brands trying to connect with audiences across an array of social channels, the attention span of people is on a decline.

Businesses need to quickly figure out what’s best for their audiences in order to generate better engagement and increased brand loyalty.

Here are five crucial social media trends that will have the maximum impact on your social media strategy in 2018 and ahead.

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Social networks can learn about you through your friends

Some people might think that online privacy is, well, a private matter. If you don’t want personal information getting out online, then you can just not put it out there. Right? Wrong. Keeping your information private isn’t solely your choice anymore. Friends can play a big role in your privacy, new data show. And the more they share on a social network, the more that social network can figure out about you.

Someone who joins a social network — such as Snapchat, Instagram or Facebook —wants to find their friends. Often, the social network can help. Many apps offer to import contact lists from your phone or e-mail. These apps then use that information to find matches with people already in the network, and suggest them to you.

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Instagram is integrating recommendations into user feeds

Instagram is starting to roll out recommended posts directly into users’ home feeds, according to TechCrunch.

Previously, the home feed was dedicated to posts from accounts that users follow as well as ads, whereas recommended posts were located solely in the Explore tab.

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2018 Biggest Social Media Trends For Business

Just how dominant a business tool was social media in 2017? Despite being involved in an investigation by Congress, Facebook reported its highest earnings ever in Q3, up nearly 50% from a year ago.

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Teach Students To Use Social Media (The Right Way) And The Possibilities Are Endless

CJ Marple wanted to teach his young students how quickly information can spread on the Internet.

So earlier this year, the third-grade science teacher wrote up a tweet with the help of his students, asking for other users to retweet the message, or even reply to the message with their location.

The Kansas teacher says he expected 1,000 or so retweets, but within days the tweet went viral and gained more than 227,000 retweets and 75,000 replies from users all over the world. His students, who are probably a little too young for their own social media accounts, learned a lot that week about the power of social media.

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Twitter pushes trending news to the top of your feed

As Facebook fights its own fake news problem, Twitter looks like it's interested in finding more ways to push news content to its microblogging service. According to a report at BuzzFeed, Twitter has confirmed that it is testing new algorithm-curated timelines when big events happen, then putting tweets from news organizations and other users at the top of your timeline. So far, Twitter says humans are involved in story selection, but a Twitter spokesperson told BuzzFeed that it could be come only algorithmic in the future.

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Twitter pushes trending news to the top of your feed

As Facebook fights its own fake news problem, Twitter looks like its interested in finding more ways to push news content to its microblogging service. According to a report at BuzzFeed, Twitter has confirmed that it is testing new algorithm-curated timelines when big events happen, then putting tweets from news organizations and other users at the top of your timeline. So far, Twitter says humans are involved in story selection, but a Twitter spokesperson told BuzzFeed that it could be come only algorithmic in the future.

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Is Facebook Limiting News Feeds To 25 Friends?

As Reuben alluded and our sources VERIFY, the claim is false. Facebook did announce, in January, it would be changing its status update philosophy.

The social network explained it is going to try to show users more posts from friends that have "meaningful interactions." It plans to do that by reducing the number of articles and videos that appear on news feeds.

But, Facebook never said it is limiting news feed updates to 25 friends. Rather, the social network is just prioritizing the statuses users will be more inclined to see.

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Planning Your 2019 Social Media Calendar? 13 Tactics To Step Up Your Game

In recent years, social media platforms have evolved from simple communication channels to full-blown news and entertainment hubs. From Facebook Watch to this years innovations like IGTV and Snapchat’s Story Ads, social platforms are stepping up the game to keep its users engaged and entertained -- and your company should not be too far behind.

If you want to keep up with the latest social media trends, you will have to reevaluate your strategy with an eye toward the future of this ever-evolving industry. Below, Forbes Agency Council members share 13 ways to step up your social game in 2019.

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End nears for RSS? Firefox 64 to drop built-in support for RSS, Atom feeds, says Mozilla

Mozilla to kill off RSS features in Firefox because they're hardly used and would take too much effort to modernize.

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5 Predicted Social Media Trends for 2019

Hootsuite, the master of everything social, has released a report detailing its predictions for the future of social media trends in 2019, and it is a must-read. After surveying thousands of customers and consulting with several top-notch market research firms, Hootsuite has distilled some crucial information and understanding for every business owner, large and small.

The information they reviewed covers just about anything and everything one could think to ask about when it comes to social media, from the best way to channel customer service to big-picture ideas for customer relations overall. The top social media trends for 2019, then, can be understood very specifically, and very broadly.

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The Future of Education: How Cities Can Leverage Community Assets, Social Networks, and Personal Passions in Extending Their Learning Systems Beyond the Classroom

Schools can not do it all. We have known this for a long time, yet we often seem to deny this reality in policy and action. For decades we have piled expectations onto our schools, asking them to develop scholars, citizens, and workers and to provide for the academic, nutritional, social, and developmental needs of children. Schools, as critics are quick to point out, invariably fall short of these expectations.

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Independence of regulatory decisions made by the Australian Pesticides and Veterinary Medicines Authority (APVMA) / Rural and Regional Affairs and Transport References Committee

Australia. Parliament. Senate. Rural and Regional Affairs and Transport References Committee, author, issuing body