on Super-assembled core/shell fibrous frameworks with dual growth factors for in situ cementum–ligament–bone complex regeneration By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2459-2471DOI: 10.1039/D0BM00102C, PaperTian Ding, Jianhua Li, Xingshuang Zhang, Lingqian Du, Yang Li, Dengwang Li, Biao Kong, Shaohua GeIn this work, a super-assembled framework (SAF) was fabricated to achieve sequential delivery of bFGF and BMP-2 for in situ cementum–ligament–bone complex regeneration.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A nanosystem loaded with perfluorohexane and rose bengal coupled upconversion nanoparticles for multimodal imaging and synergetic chemo-photodynamic therapy of cancer By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2488-2506DOI: 10.1039/C9BM02081K, PaperHai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao RanA novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Bioinspired inorganic nanoparticles and vascular factor microenvironment directed neo-bone formation By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2627-2637DOI: 10.1039/D0BM00041H, PaperHwan D. Kim, Jungha Park, Sivashanmugam Amirthalingam, R. Jayakumar, Nathaniel S. HwangVEGF-overexpressing human tonsil-derived stem cells (VEGF-hTMSCs) and a whitlockite microenvironment induce vascularized bone tissue formation in biodegradable polymeric scaffolds.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Assembly of FN-silk with laminin-521 to integrate hPSCs into a three-dimensional culture for neural differentiation By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2514-2525DOI: 10.1039/C9BM01624D, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Carolina Åstrand, Veronique Chotteau, Anna Falk, My HedhammarThe functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A medical adhesive used in a wet environment by blending tannic acid and silk fibroin By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2694-2701DOI: 10.1039/D0BM00322K, PaperXijie Gao, Qiyuan Dai, Longtao Yao, Hua Dong, Qingtao Li, Xiaodong CaoA medical adhesive called TASK based on polyphenol-gel systems was developed and showed wet-adhesive, stretchable, self-healing and restorable properties.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Injectable hydrogel systems with multiple biophysical and biochemical cues for bone regeneration By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2537-2548DOI: 10.1039/D0BM00104J, PaperWeinan Cheng, Zhaozhao Ding, Xin Zheng, Qiang Lu, Xiangdong Kong, Xiaozhong Zhou, Guozhong Lu, David L. KaplanTunable multiple angiogenic and osteogenic cues were introduced into hydrogel systems simultaneously to optimize the niches for bone regeneration.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on NIR-emitting semiconducting polymer nanoparticles for in vivo two-photon vascular imaging By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2666-2672DOI: 10.1039/C9BM02063B, PaperXiao-Ting Gong, Wenguang Xie, Jing-Jing Cao, Shengxiang Zhang, Kanyi Pu, Hao-Li ZhangA NIR-emitting TPF probe (NESPN) was prepared using semiconducting polymers and used for continuously monitoring the whole process of ischemic stroke and subsequent reperfusion. This work provides a new and versatile tool for vascular research and diagnosis of vascular diseases.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Spatial immobilization of endogenous growth factors to control vascularization in bone tissue engineering By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2577-2589DOI: 10.1039/D0BM00087F, PaperMarta R. Casanova, Catarina Oliveira, Emanuel M. Fernandes, Rui L. Reis, Tiago H. Silva, Albino Martins, Nuno M. NevesAn engineered biofunctional system comprises endogenous BMP-2 and VEGF bound in a parallel pattern. It successfully enabled obtaining the spatial osteogenic and angiogenic differentiation of human hBM-MSCs under basal culture conditions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2673-2681DOI: 10.1039/C9BM01957J, PaperAngela Saccardo, Mikhail Soloviev, Enrico FerrariEngineering of the neuronal SNARE proteins yields chimeric bio-materials that reversibly assemble and disassemble at set temperatures.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2611-2626DOI: 10.1039/C9BM01965K, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.F. A. A. Ruiter, L. E. Sidney, K. L. Kiick, J. I. Segal, C. Alexander, F. R. A. J. RoseThe fabrication and application of a biocompatible peptide conjugated thermo-responsive fibrous scaffolds for cellular phenotype support and enzymatic-free passaging of mammalian cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Highly responsive and rapid hydrogen peroxide-triggered degradation of polycaprolactone nanoparticles By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2394-2397DOI: 10.1039/C9BM02019E, CommunicationPeng-Hao Hsu, Carina Arboleda, Alexandra Stubelius, Ling-Wei Li, Jason Olejniczak, Adah AlmutairiNanoparticles formulated from fast-degrading oxidation-responsive polycaprolactone are responsive to 50 μM of H2O2.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Topography induced stiffness alteration of stem cells influences osteogenic differentiation By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2638-2652DOI: 10.1039/D0BM00264J, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Liangliang Yang, Qi Gao, Lu Ge, Qihui Zhou, Eliza M. Warszawik, Reinier Bron, King Wai Chiu Lai, Patrick van RijnTopography-driven alterations to single cell stiffness rather than alterations in cell morphology, is the underlying driver for influencing cell biological processes, particularly stem cell differentiation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2434-2446DOI: 10.1039/D0BM00182A, PaperJann Harberts, Undine Haferkamp, Stefanie Haugg, Cornelius Fendler, Dennis Lam, Robert Zierold, Ole Pless, Robert H. BlickNanostructured substrates such as nanowire arrays form a powerful tool for building next-generation medical devices.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A novel peptide targeting gastrin releasing peptide receptor for pancreatic neoplasm detection By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2682-2693DOI: 10.1039/D0BM00162G, PaperYuanbiao Tu, Ji Tao, Fang Wang, Peifei Liu, Zhihao Han, Zhaolun Li, Yi Ma, Yueqing GuThe designed novel peptide GB-6 with targeted GRPR-binding possesses more favorable pharmacokinetic properties and metabolic stability, as well as superior tumor-targeting ability in pancreatic cancer models, relative to BBN7–14.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Particle-mediated delivery of frataxin plasmid to a human sensory neuronal model of Friedreich's ataxia By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2398-2403DOI: 10.1039/C9BM01757G, CommunicationEwa Czuba-Wojnilowicz, Serena Viventi, Sara E. Howden, Simon Maksour, Amy E. Hulme, Christina Cortez-Jugo, Mirella Dottori, Frank CarusoMultilayered particles in gene therapy for Friedreich's ataxia induce a 27 000-fold increase in frataxin gene expression in a patient-derived cell model.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on An intelligent vancomycin release system for preventing surgical site infections of bone tissues By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00255K, PaperYuan Li, Guang Li, Xiaoling Sha, Litao Li, Kuo Zhang, Daohong Liu, Yanfei Hao, Xu Cui, Lei Wang, Hao WangAn intelligent anti-bacterial system can be constructed on implants during surgery.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00425A, PaperKun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong WangA universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A super-stretchable, self-healing and injectable supramolecular hydrogel constructed by a host–guest crosslinker By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00290A, PaperYang Zhou, Yuanhao Zhang, Zhaobo Dai, Fang Jiang, Jia Tian, Weian ZhangSupramolecular hydrogels based on host–guest interactions have drawn considerable attention due to their unique properties and promising applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00474J, PaperQiwen Wang, Jie Shen, Enqi Mo, Haotian Zhang, Jianwei Wang, Xiurong Hu, Jun Zhou, Hongzhen Bai, Guping TangAn H+-modified montmorillonite (H-MMT) was prepared using an acid modification method to obtain powerful absorption ability as a theranostic platform for both metabolic syndrome and gastric mucosa protection.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00312C, PaperKunnumpurathu Jibin, Jayaram S. Prasad, Giridharan Saranya, Sachin J. Shenoy, Kaustabh K. Maiti, Ramapurath S. JayasreeGold–graphene nanohybrid for simultaneous dual-imaging guided triple therapy as a new paradigm in light-triggered cancer theranostics. The material demonstrates excellent therapeutic efficacy and treatment monitoring features.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00311E, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim, Keun-Hong ParkThe use of nanoscale materials (NMs) could cause problems such as cytotoxicity, genomic aberration, but the impacts of NM exposure during pregnancy remain uncharacterized in the context of clinical applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00566E, PaperSangmin Lee, Yun-Young Chang, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Yang-Hun Jung, Jeong-Ho Yun, Heungsoo ShinAlthough titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone–implant interface is still required.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Functionalized Biomaterials to Combat Biofilm By pubs.rsc.org Published On :: Biomater. Sci., 2020, Accepted ManuscriptDOI: 10.1039/D0BM00526F, MinireviewDan-ni Huang, Jing Wang, Kefeng Ren, Jian JiPathogenic microbial biofilms readily form on implantable medical devices or human tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive strategies of biofilms, leaving a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting CD44v6 receptor in colon cancer cells By pubs.rsc.org Published On :: Biomater. Sci., 2020, Accepted ManuscriptDOI: 10.1039/D0BM00556H, PaperAna Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno SarmentoColorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Serum miRNAs are differentially altered by ethanol and caffeine consumption in rats By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,842-849DOI: 10.1039/C9TX00069K, PaperM. Martinez, I. M. U. Rossetto, R. M. S. Arantes, F. S. N. Lizarte, L. F. Tirapelli, D. P. C. Tirapelli, L. G. A. Chuffa, F. E. MartinezAlcoholism is a multifactorial disease with high risk for dependence determined by genetic background, environmental factors and neuroadaptations.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,868-874DOI: 10.1039/C9TX00113A, PaperNeo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel OluwafemiIn this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Tin thiocarbonohydrazone complexes: synthesis, crystal structures and biological evaluation By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,862-867DOI: 10.1039/C9TX00109C, PaperJin Wang, Yu-Ting Wang, Yan Fang, Yan-Li Lu, Ming-Xue LiThree organotin thiocarbonohydrazone complexes have been synthesized, and growth inhibition assays indicated that complex 3 has the highest tumor cell selectivity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Kaempferol derivatives isolated from Lens culinaris Medik. reduce DNA damage induced by etoposide in peripheral blood mononuclear cells By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,896-907DOI: 10.1039/C9TX00176J, PaperMagdalena Kluska, Michał Juszczak, Daniel Wysokiński, Jerzy Żuchowski, Anna Stochmal, Katarzyna WoźniakBioactive compounds isolated from plants are considered to be attractive candidates for cancer therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use” by D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489 By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1057-1058DOI: 10.1039/C9TX00158A, CommentMichael E. Mullins, Mark C. Yarema, Marco L. A. Sivilotti, Margaret Thompson, D. Adam Algren, Michael C. Beuhler, Christopher P. HolstegeWe point out an acetylcysteine protocol that a previous article (D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489–498) overlooked.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Characteristic synergistic cytotoxic effects toward cells in graphene oxide dressing with cadmium and copper ions By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,908-917DOI: 10.1039/C9TX00146H, PaperYiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui WangCadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Ex vivo toxicological evaluation of experimental anticancer gold(I) complexes with lansoprazole-type ligands By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,885-895DOI: 10.1039/C9TX00149B, PaperNatalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A. M. de Graaf, Geny M. M. Groothuis, Angela CasiniNovel experimental anticancer gold-based compounds were studied for their mechanisms of toxicity in healthy rat kidney and liver tissues, using the Precision Cut Tissue Slices (PCTS) technique.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Gynura divaricata ameliorates hepatic insulin resistance by modulating insulin signalling, maintaining glycolipid homeostasis and reducing inflammation in type 2 diabetic mice By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,928-938DOI: 10.1039/C9TX00191C, PaperXuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing ZhangOral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,918-927DOI: 10.1039/C9TX00186G, PaperLi Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhouα-Lipoic acid antagonizes paraquat toxicity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Thyroid endocrine status and biochemical stress responses in adult male Wistar rats chronically exposed to pristine polystyrene nanoplastics By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,953-963DOI: 10.1039/C9TX00147F, PaperFatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad BabaeiAt this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Environmental distribution of the neurotoxin L-BMAA in Paenibacillus species By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,781-783DOI: 10.1039/C9TX00203K, ViewpointPeter B. Nunn, Geoffrey A. CoddThe neurotoxic amino acid, 3-N-methyl-2,3-diaminopropanoic acid (BMAA), known in plants of the genus Cycas and in aquatic cyanobacteria and other organisms, is a component of antibiotic peptides in two species of Paenibacillus.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1059-1059DOI: 10.1039/C9TX00216B, Comment Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.D. Nicholas Bateman, James W. DearMullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Biogenic Aspergillus tubingensis silver nanoparticles’ in vitro effects on human umbilical vein endothelial cells, normal human fibroblasts, HEPG2, and Galleria mellonella By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,789-801DOI: 10.1039/C9TX00091G, PaperCristiane Angélica Ottoni, Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de SouzaBiogenic silver nanoparticles are ecofriendly and offers valuable possibilities of applications in several industrial areas.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,994-1001DOI: 10.1039/C9TX00126C, PaperYan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. LauA comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Innovative models for in vitro detection of seizure By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,784-788DOI: 10.1039/C9TX00210C, Review ArticleKimberly L. Rockley, Ruth A. Roberts, Michael J. MortonNew technologies offer the opportunity to screen for seizure liability in vitro, avoiding costly failures in preclinical and clinical development.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Novel evaluation of sevoflurane anesthetic exposure on the testicular germ cells of neonatal male mice By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,988-993DOI: 10.1039/C9TX00193J, PaperAli Raza Ebrahim Soltani, Abdolmohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad SistaniInhalatory anesthetics may impact spermatogenesis and sexual behavior.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Cigarette smoke inhalation aggravates diabetic kidney injury in rats By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,964-971DOI: 10.1039/C9TX00201D, PaperSongling Jiang, Do Van Quan, Jae Hyuck Sung, Moo-Yeol Lee, Hunjoo HaFour weeks of exposure to cigarette smoke aggravated the progression of diabetic kidney injury including inflammation, fibrosis, and oxidative stress.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Effects of moderate red wine on cardiovascular risk factors in diabetics: a systematic review and meta-analysis of randomized controlled trials By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,979-987DOI: 10.1039/C9TX00227H, PaperSaavia Alice Naame, Decheng Li, Ruixue HuangDiabetes mellitus is of major public health concerns; its incidence is continuously increasing.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic injuries by regulation of genes in rats By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,815-832DOI: 10.1039/C9TX00157C, PaperJawaid Ahmed Zai, Muhammad Rashid Khan, Zaib un Nisa Mughal, Riffat Batool, Irum Naz, Sonia Maryam, Zartash ZahraAlteration in expression of ER stress associated genes, inflammatory genes and antioxidant biochemical induced with CCl4 in liver of rats were restored towards the control rats by co-administration of methanol extract of Iphiona aucheri to rats.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Astilbin attenuates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB pathway By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1002-1008DOI: 10.1039/C9TX00222G, PaperJing Li, Zhaowei Gu, Yue Liu, Yu Wang, Min ZhaoIschemic stroke is the second most common cause of death worldwide and cerebral ischemia/reperfusion (I/R) injury also leads to serious tissue damage.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1016-1027DOI: 10.1039/C9TX00179D, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas LuchTo answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Application of the direct peptide reactivity assay (DPRA) to inorganic compounds: a case study of platinum species By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,802-814DOI: 10.1039/C9TX00242A, PaperJocelyn D. C. Hemming, Mark Hosford, Martin M. ShaferThe in chemico Direct Peptide Reactivity Assay (DPRA) was developed as a non-animal, relatively high throughput, screening tool for skin sensitization potential.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Benzoquinone alters the lipid homeostasis in Saccharomyces cerevisiae By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1035-1041DOI: 10.1039/C9TX00139E, PaperAbhishek Raj, Vasanthi NachiappanBQ exposure inhibited cell growth, increased the ROS-mediated apoptosis, and altered the phospholipids that resulted in membrane proliferation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Cytotoxic effect of silica nanoparticles against hepatocellular carcinoma cells through necroptosis induction By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1042-1049DOI: 10.1039/C9TX00240E, PaperYuexiang Niu, Engong Tang, Qingan ZhangHepatocellular carcinoma (HCC) is a common cancer that affects people worldwide with high morbidity and mortality, and its resistance to current chemotherapeutic drugs is a serious concern.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on The protective effect of thymoquinone on tert-butylhydroquinone induced cytotoxicity in human umbilical vein endothelial cells By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1050-1056DOI: 10.1039/C9TX00235A, PaperZahra Karimi, Maryam Ghaffari, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan2-tert-Butyl-4-hydroquinone (TBHQ) is used for inhibition of oxidative rancidity in the food industry.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on AIIB extends $500 mn loan to India to deal with coronavirus crisis By www.business-standard.com Published On :: Fri, 08 May 2020 10:44:00 +0530 The bank's board of directors has approved a loan to India to strengthen the preparedness of the country's national health system Full Article
