The present invention relates to I- and II-type crystals of L-α-glyceryl phosphoryl choline, and to a method for preparing same. More particularly, the present invention relates to noble I- and II-type anhydride crystals of L-α-glyceryl phosphoryl choline, which have a higher purity than conventional liquid L-α-glyceryl phosphoryl choline, and one advantage of which is that formulations and dosages of pharmaceuticals are easily modified, and another advantage of which is that the hygroscopicity of the crystals are much lower than that of conventional polymorphic crystals, providing excellent stability during storage. The present invention also relates to a method for preparing the I- and II-type crystals of L-α-glyceryl phosphoryl choline. The I-type crystal of L-α-glyceryl phosphoryl choline is characterized by having an onset temperature of 147° C. and an absorption peak of 150° C. based on differential scanning calorimeter (DSC) analysis, and by having diffraction patterns where 2θ-diffraction angles are 9.8±0.2°, 12.0±0.2°, 14.3±0.2°, 15.8±0.2°, and 19.6±0.2° based on X-ray diffraction (XRD) analysis. The II-type crystal of L-α-glyceryl phosphoryl choline is characterized by having an onset temperature of 62° C. and an absorption peak of 66° C., and an onset temperature of 141° C. and an absorption peak of 145° C. based on DSC analysis, and having diffraction patterns where 2θ-diffraction angles are 10.3±0.2°, 12.2±0.2°, 13.4±0.2°, 14.8±0.2°, and 20.6±0.2° based on XRD analysis.

The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.

The present invention is directed to an isomerized alpha olefin sulfonate and a method of making the same wherein the isomerized alpha olefin sulfonate is derived from sulfonating an isomerized alpha olefin with sulfur trioxide in the presence of air thereby producing an isomerized alpha olefin sulfonic acid, wherein the isomerized alpha olefin is derived from the isomerization of C12-C20 normal alpha olefins; and neutralizing the isomerized alpha olefin sulfonic acid with a source of an alkali metal or ammonium or substituted ammonium ion.

A phosphazene compound having a vinyl group is manufactured by a reaction between a vinyl compound and a phosphazene compound having a hydroxyl group and added to a resin composition for manufacturing a prepreg or a resin film so as to be applicable to copper-clad laminates and printed circuit boards to thereby achieve satisfactory circuit laminate properties, namely low coefficient of thermal expansion, low dielectric properties, heat resistant, fire resistant, and halogen-free.

A method for producing a silica-supported catalyst comprising Mo, V. Nb, and a component X (Sb and/or Te) to be used in a vapor phase catalytic oxidation or ammoxidation of proprane, comprising the steps of: (I) preparing a raw material mixture solution by mixing Mo, V, Nb, component X, a silica sol, and water;(II) obtaining a dry powder by drying the raw material mixture solution; and(III) obtaining a silica-supported catalyst by calcining the dry powder, wherein the silica sol contains 10 to 270 wt ppm of nitrate ions based on SiO2.

Organophosphorus compounds, catalytic systems comprising a metallic element forming a complex with the organophosphorus compounds and methods of hydrocyanation and of hydroformylation employed in the presence of the catalytic systems are described.

The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride.

A method and apparatus for using an ad hoc peer-to-peer distributed message bus is provided. The method may include determining, by a local bus node, using a first power level communication protocol, that a remote bus node is available, obtaining, by the local bus node, connection information from the remote bus node using a second power level communication protocol, wherein the connection information comprises connection information for one or more remote endpoints associated with the remote bus node, and generating one or more local virtual endpoints, wherein each of the one or more local virtual endpoints corresponds to each of the one or more remote endpoints, and wherein the remote endpoint is described with reference to a well-known name, unique to the remote endpoint.

An exemplary embodiment of the invention relates to a system and method for providing digital messaging services received from multiple sources over a communications network. The system includes a client system, including a display screen coupled to a communications link; a workstation including a web browser, a memory, and a processor, said workstation coupled to said communications link; a hosting system, including a graphics server, a content server, and a scheduling server, each in communication with each other via a communications link; and a workstation and data storage device coupled to the communications link; and a data storage device for storing data utilized by said hosting system. The client system requests and receives digital messaging services from said hosting system under a subscription agreement. Digital messaging services include advertisements procured from said client system, and one or more local content providers, national advertisers, local advertisers, corporate marketing groups, and advertising agencies. Interactive digital messaging services are also available through the present invention. A user accesses these services via a variety of input devices; such as a bar code scanner, a wireless telephone or personal digital assistant, a kiosk with touch screen design, microphone, or other similar input device.

A printing device includes a printing device side wireless communication unit configured to execute wireless communication with a mobile terminal, an operation acquisition unit configured to acquire user operation thereof, and a processor. The processor is configured to acquire operation data which is generated as the operation acquisition unit acquires a user operation, acquire establishment data which is generated as the printing device side wireless communication unit establishes a wireless communication with the mobile terminal, and issue a request control to control the printing device side wireless communication unit to transmit request data requesting the mobile terminal to transmit print data necessary for printing, via the wireless communication, when the establishment data is acquired, the request control being issued in accordance with the operation data as acquired.

A method, system and computer program product are disclosed for user initiated rule based restrictions on sending messages from a sender to a receiver in a communications network. The receiver establishes a set of rules for the sender that allows the sender a limited number of defined messages events with the receiver. The defined message events may be messages or message sessions. When the sender attempts to send a message to the receiver, it is determined whether a message session currently exists between the sender and the receiver. If a current session exists, the rules set by the receiver are used to determine if the message is allowed to be sent to the receiver. If a session does not currently exist, the rules are used to determine whether a new session is allowed. If a new message session is allowed, a new session is established, and the message is sent to the receiver during the new session.

A CPU executes a communication partner search process for searching for a communication partner (another game machine). The CPU confirms received data content. If identification information included in the received data matches, application identification information saved in a wireless communication module is compared with application identification information included in the received data. When the pieces of application identification information match, a notice that another game machine having exchange data corresponding to the matched application identification information is found is given to a main body. Then, giving/receiving of exchange data is executed to/from another game machine.

According to one embodiment, a method comprises evaluating messages between nodes of a distributed computing environment. Based on timing relationships of the messages, probability of causal links between pairs of messages determined. Based on the determined probability, at least one causal path comprising a plurality of causal links is inferred. Further, an overall probability that the inferred causal path is accurate is determined. In certain embodiments, the overall probability is output for the corresponding causal path to provide an indication of the confidence of the accuracy of such inferred causal path.

Various arrangements for creating and using generic universal resource indicators are presented. To create a generic universal resource indicator, one or more parameters of a universal resource indicator may be identified. An interface that permits a parameter of the one or more parameters to be selected and mapped to a variable may be presented. A selection of the parameter for mapping may be received. An indication of the variable to map to the parameter of the selection may also be received. The generic universal resource indicator having a generic parameter corresponding to the parameter of the selection may be created.

A method is described for detecting the time messages in the faulty signal of a time-signal transmitter comprising the steps below. Probabilities are assigned to the received information/bits as they are received and whose sign specifies the value of the bit and whose numerical value indicates the certainty of reception. Except for the bits designating the minute information, the probabilities of successive time messages are totaled with time correctness in a one-dimensional memory field. From the totaled probabilities, a reduced time message is reconstructed that initially contains no information on the minutes. If the reconstructed time message does not change over two successive time intervals, and if preset minimum values for the number of probabilities are exceeded for all bits, then the reduced time message is recognized as being correct. The minutes are determined separately and added to the time message recognized as being correct.

A radio paging selective receiver determines that a received message is unread based on the time difference between the message reception time and the current time being larger that some predetermined value of time, and the paging selective receiver provides an indication of the unread message by displaying the reception time of the unread message in a second fashion which is visibly different from a first fashion normally used to display the current time.

An LCD is integrated with the cover glass of a wrist watch radio paging receiver which indicates the time data with a dial plate and hands, and a message is displayed on the cover glass by controlling this LCD. In this message display, the parts of the characters indicating the message are made transparent and the remaining parts intercept light. In this manner, message display is made possible by the difference in light transmissivity.

A prefetch optimizer tool for an information handling system (IHS) may improve effective memory access time by controlling both hardware prefetch operations and software prefetch operations. The prefetch optimizer tool selectively disables prefetch instructions in an instruction sequence of interest within an application. The tool measures execution times of the instruction sequence of interest when different prefetch instructions are disabled. The tool may hold hardware prefetch depth constant while cycling through disabling different prefetch instructions and taking corresponding execution time measurements. Alternatively, for each disabled prefetch instruction in the instruction sequence of interest, the tool may cycle through different hardware prefetch depths and take corresponding execution time measurements at each hardware prefetch depth. The tool selects a combination of hardware prefetch depth and prefetch instruction disablement that may improve the execution time in comparison with a baseline execution time.

The present invention provides α-keto alkylperacids and methods for producing and using the same. In particular, α-keto alkylperacids are useful as antimicrobial agents.

A reaction system suitable for production of a methionine salt contains a reactive rectification column containing a weir having a height of 100 mm or more.

A method of making modified carbon materials for use in fabricating fuel cell components. The modified carbon may comprise pendant fluorocarbon groups bonded covalently bonded thereto. In one embodiment, a mixture is formed and comprises carbon material suitable for use in a fuel cell component, an organic solvent, a compound having the general formula I—R wherein R is a fluorocarbon, and a reductant.

An object of the present invention is to provide a substance characterized by ability to reduce oxidized coenzyme Q10 and ability to stabilize reduced coenzyme Q10, which contains nutrients, has a favorable taste, and is excellent in general versatility, and a method for using the same. The present invention relates to a method for producing reduced coenzyme Q10 comprising reducing oxidized coenzyme Q10 with a particular amino acid. The present invention also relates to a method for stabilizing reduced coenzyme Q10 in the presence of a particular amino acid and a composition stabilized by the method.

The invention describes new structures of the nucleotide conjugates (nuc-macromolecules) comprising at lease one nucleotide moiety coupled to at least one macromolecular compound via a short linker. These conjugates can be used as substrates for various kinds of polymerizing enzymes in the enzymatic synthesis of nucleic acids. In particular, these compounds can be used for labeling nucleic acids.

The present invention provides for an electronic device having cryptographic computation means arranged to generate cryptographic data within the device for enhancing security of communications therewith, the device including an onboard power supplying means arranged to provide for the driving of the said cryptographic computational means, and so as to provide a device by way of a manufacturing phase and a post manufacturing phase arranged for distribution and/or marketing of the device, and wherein the step of generating the cryptographic data occurs during the post manufacturing phase.

Security measures for tokens comprise storing security rules associated with a generated token in a memory. A processor, communicatively coupled to the memory, accesses the security rules associated with the generated token and determines whether to encrypt the generated token by applying at least a portion of the security rules to the generated token. The processor encrypts the generated token. An interface, communicatively coupled to the processor, communicates the encrypted token to a mobile device associated with a user.

A power-saving network management server, which is coupled to a network system including a network device and manages a state of power to the network device, wherein the power-saving network management server is configured to: store network configuration information and task allocation information; determine starting or stopping of the power supply to the port of the network device based on the updated network configuration information and task allocation information; store a determination result of the starting or stopping of the power supply to the port as a port determination result; and control the power supply to the port of the network device based on the port determination result.

A multi-cluster processing system and a method of operating a multi-cluster processing system are provided. The multi-cluster processing system includes: a first cluster including a plurality of first-type cores: a second cluster including a plurality of second-type cores; and a control unit configured to monitor loads of the first-type cores and the second-type cores, wherein when utilization of at least one of enabled first-type cores exceeds a predetermined threshold utilization of each of the first-type cores, the control unit enables at least one of disabled first-type cores in a first mode, and the control unit enables at least one of the disabled second-type cores and disables the first cluster in a second mode, wherein an amount of computation per unit of time of each of the second-type cores is greater than an amount of computation per unit of time of each of the first-type cores.

An integrated-circuit memory controller outputs to a memory device a first signal in a first state to enable operation of synchronous data transmission and reception circuits within the memory device. A transaction queue within the memory controller stores memory read and write requests that, to be serviced, require operation of the synchronous data transmission and reception circuits, respectively, within the memory device. Power control circuitry within the memory controller determines that the transaction queue has reached a predetermined state and, in response, outputs the first signal to the memory device in a second state to disable operation of the synchronous data transmission and reception circuits within the memory device.

Techniques for implementing identification and management of unsafe optimizations are disclosed. A method of the disclosure includes receiving, by a managed runtime environment (MRE) executed by a processing device, a notice of misprediction of optimized code, the misprediction occurring during a runtime of the optimized code, determining, by the MRE, whether a local misprediction counter (LMC) associated with a code region of the optimized code causing the misprediction exceeds a local misprediction threshold (LMT) value, and when the LMC exceeds the LMT value, compiling, by the MRE, native code of the optimized code to generate a new version of the optimized code, wherein the code region in the new version of the optimized code is not optimized.

A method and device for controlling content that includes plural display pages in a sequence, the method including: displaying a current page included in the content; receiving a user input to or above a display screen of the display unit for changing from the current page to another page of the content; extracting fingerprint information from the user input; determining whether the content of the another page is or is not accessible based on the extracted fingerprint information; if all of the content of the another page is determined to be accessible based on the extracted fingerprint information, displaying the another page; and if any of the content of the another page is determined not to be accessible based on the extracted fingerprint information, displaying a page following the current page without displaying content of the another page that was determined not to be accessible.

The present invention has an object to measure lymphatic pressure with more safety and ease at lower cost. To achieve this, a lymphatic pressure-measuring system 1 includes: a manchette 11 fitted on a vital observation portion; a measurement unit 13 that measures and outputs pressure of the manchette 11; an infrared camera 21 that detects fluorescence emitted from fluorescent dye previously injected into a lymph vessel in the vital observation portion; and an image processing device 22 that generates and displays an image showing a position of the fluorescent dye in the lymph vessel based on a detection result of the infrared camera 21. The infrared camera 21 repeats the detection while the pressure of the manchette 11 decreases from first pressure to block a lymph flow in the vital observation portion to second pressure at restart of the lymph flow. The measurement unit 13 repeats the measurement during the period.

The described invention provides a disposable handheld biopsy device for taking biopsies, the biopsy device comprising a tissue cutting assembly which has features to control the tissue length that will be severed by the cutting assembly; and a vacuum assembly which has features to control the vacuum level. The disposable handheld biopsy device of the described invention is simple, lightweight, portable, and cost effective to manufacture and dispose of.

A reusable needle guide suitable for an ultrasonic probe to be use for an endocavity examination of a patient is disclosed. The needle guide basically comprises at least a first and second guide members and a mounting (e.g., clamp) assembly. The clamp assembly serves to releasably mount the needle guide on the probe. The first guide member has a first passageway-forming surface. The second guide member has a second passageway-forming surface. The guide members are connected together to enable them to be pivoted from a closed orientation to an open orientation and vice versa. The first and second passageway-forming surfaces form an elongated passageway to guide a needle therethrough when in the closed orientation. The first and second passageway-forming surfaces are disposed at an angle to each other when they are in the open orientation, whereupon the first and second passageway-forming surfaces can be readily cleaned.

A novel phenylcarbamate compound and a pharmaceutical composition containing the same are provided. More specifically, a novel phenylcarbamate compound, a composition for muscle relaxation containing the phenylcarbamate compound as an active ingredient, and a method of muscle relaxation comprising administering a therapeutically effective amount of the phenylcarbamate compound, are provided.

A feed additive includes at least one of p-thymol, a salt derivative and an ester derivative thereof for animals.

The present invention relates to a process for synthesizing a multifunctional compound, including the reaction of a compound of formula (II) with atmospheric or molecular oxygen, in the presence of at least one aldehyde of formula (III), and optionally in the presence of at least one catalyst or at least one radical initiator; wherein: R10, R20, R30, R40, R50, L2, R60, R7, R8, and R9 are as described in the claims. The invention also relates to the use of these compounds as monomers for the preparation of polyurethane. The invention also relates to the use of these compounds as monomers of polymers or of biopolymers.

A phenyl alkyl carbamate derivative compound and a pharmaceutical composition containing the compound are provided. More specifically, the phenyl alkyl carbamate derivative compound and a pharmaceutically acceptable salt thereof, a composition for muscle relaxation containing the phenyl alkyl carbamate derivative compounds and/or pharmaceutically acceptable salt thereof as an active ingredient, and a method of muscle relaxation comprising administering a pharmaceutically effective amount of the phenyl alkyl carbamate derivative compound and/or a pharmaceutically acceptable salt thereof to a subject in need of to a subject in need of, are provided.

An object of the present invention is to improve the stability of an ethylenically unsaturated compound having an isocyanate group in the molecule by preventing a polymerization of the ethylenically unsaturated compound. The present invention relates to a stabilizing composition for an isocyanate group-containing ethylenically unsaturated compound, comprising: an isocyanate group-containing ethylenically unsaturated compound (A) which comprises one or more isocyanate groups and one or more ethylenically unsaturated groups in the molecule; and a stabilizing agent (B) which is a compound in which at least one of the ethylenically unsaturated groups in the compound (A) is replaced with an alkyl group which may have a substituent.

The present invention relates to norbornene-ester-based derivatives, to a method for preparing same, and to the uses thereof. This compound may be used as a plasticizer which can replace a phthalate-based plasticizer.

This disclosure relates to a method for preparing alkyl lactate with high yield and high selectivity, comprising the step of reacting glycerol with water or alcohol in the presence of a catalyst. In addition, the present invention provides a method for efficiently preparing lactamide using the alkyl lactate.

The invention relates to fatty acid acylated salicylate derivatives; compositions comprising an effective amount of a fatty acid acylated salicylate derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a fatty acid acylated salicylate derivative.

Disclosed are effective and simple adsorbents and methods of using the adsorbents for removing metal impurities generated during storage, transportation and supply of organometallic compounds. The disclosed adsorbents and methods provide for the easy and effective removal of the metallic impurities or compounds generated from decomposition of the organometallic compound during its transportation, storage, and supply. Namely, the disclosed adsorbents and methods permit the stable supply of a high purity organometallic compound desired in the semiconductor and photovoltaic cell.

The invention relates to a method for producing monocarboxy-functionalized dialkylphosphinic acids, esters, and salts, characterized in that a) a phosphinic acid source (I) is reacted with olefins (IV) in the presence of a catalyst A to obtain an alkylphosphonous acid, the salt or ester (II) thereof, and b) the obtained alkylphosphonous acid, the salt or ester (II) thereof is reacted with an oxidizing agent or with an oxidizing agent and water or with oxygen and water in the presence of a catalyst B to obtain the alkylphosphonic acid derivative (III), wherein R1, R2, R3, R4 are identical or different from each other and independently represent, inter alia, H, C1-C18-alkyl, C6-C18-aryl, C6-C18-aralkyl, C6-C18-alkylaryl, X and Y are identical or different from each other and independently represent H, C1-C18-alkyl, C6-C18-aryl, C6-C18-aralkyl, C6-C18-alkylaryl, Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Zn, Ce, Bi, Sr, Mn, Cu, Ni, Li, Na, K and/or a protonated nitrogenous base, and catalysts A and B are transition metals and/or transition metal compounds and/or catalyst systems composed of a transition metal and/or a transition metal compound and at least one ligand.

Provided are a coating composition for low refractive layer including fluorine-containing compound of the following Chemical Formula 1, an anti-reflection film using the same, and a polarizer and an image display device including the same, wherein the fluorine-containing compound of the following Chemical Formula 1 has a low refractive index of 1.28 to 1.40, thereby making it possible to easily adjust a refractive index of the anti-reflection film and be usefully used as a coating material of the anti-reflection film having an excellent mechanical property such as durability, or the like.

The invention relates to a method for producing mono-aminofunctionalized dialkylphosphinic acids and esters and salts thereof by means of acrylnitriles, characterized in that a) a phosphinic acid source (I) is reacted with olefins (IV) to yield an alkylphosphonic acid, salt or ester (II) thereof in the presence of a catalyst A, b) the thus obtained alkylphosphonic acid, salt or ester (II) thereof is reacted with an acrylnitrile of formula (V) to yield a mono-functionalized dialkylphosphinic acid derivative (VI) in the presence of a catalyst B, and c) the thus obtained mono-functionalized dialkylphosphinic acid derivative (VI) is reacted to yield a mono-aminofunctionalized dialkylphosphinic acid derivative (III) in the presence of a catalyst C or a reduction agent, wherein R1, R2, R3, R4, R5, R6, R7 are the same or different and stand independently of each other, among other things, for H, C1-C18 alkyl, C6-C18 aryl, C6-C18 aralkyl, C6-C18 alkylaryl and X stands for H, C1-C18 alkyl, C6-C18 aryl, C6-C18 aralkyl, C6-C18 alkylaryl, Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Zn, Ce, Bi, Sr, Mn, Cu, Ni, Li, Na, K and/or a protonized nitrogen base, and Y stands for a mineral acid, a carboxylic acid, a Lewis acid or an organic acid, n=an integer or fractional number of 0 to 4 and the catalysts A and C are formed by transition metals, transition metal compounds and/or catalyst systems composed of a transition metal and/or a transition metal compound and at least one ligand, and catalyst B is formed by compounds forming peroxides, peroxo compounds, azo compounds, alkali metals, alkaline earth metals, alkali hydrides, alkaline earth hydrides and/or alkali alcoholates and alkaline earth alcoholates.

The present invention relates to a novel compound of Formula 1, a method for manufacturing the same, and an organic electronic device using the same, and the novel compound according to the present invention may act as a hole injection, hole transport, electron injection and transport, or light emitting material in an organic light emitting device and an organic electronic device, and the device according to the present invention shows excellent properties in terms of efficiency, a driving voltage, and stability.

The present invention is directed to 5-sec-butyl-2-(2,4-dimethyl-cyclohex-3-enyl)-5-methyl-[1,3]dioxane and a novel process for making the same.

The present invention relates to new salts of 6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol(rotigotine), their use as a medicament, for example for the treatment of CNS disorders like Parkinson Disease, RLS, fibromyalgia and/or depression, in particular through electromotive administration. The present invention relates to pharmaceutical formulations suitable for iontophoresis that provide enhanced iontophoretic delivery of rotigotine to at least one target tissue. The formulations are further characterized by good to excellent solubility of the salts in aqueous solutions.

The present invention provides a diaryl sulfone compound represented by Formula (1) below: wherein R1 to R4 and R1' to R4' are the same or different; each represents hydrogen, C1-4 alkyl, or halogen; and R5 is (thio)glycidyl, acryloyl, or the like; and a method for producing the same. According to the present invention, a novel compound useful as a monomer for producing synthetic resin having a high refractive index and excellent transparency for optical materials can be efficiently produced with a simple production process, using an inexpensive material as a starting material.

An improved process for the N-alkylation of tertiary morphinan alkaloid bases to form the corresponding quaternary morphinan alkaloid derivatives.