Online protests were held simultaneously in support of ABS-CBN.

The post Support pours for ABS-CBN as advocates hold online ‘Black Friday’ protest appeared first on Bulatlat.

ISLAMABAD: All sections of Chinese society are generously supporting Pakistan, donating medical supplies and funds, sharing experience of anti-epidemic and dispatching medical experts to overcome COVID-19 virous.According to Gwadar Pro, in recent fortnight, Chinese government and the people,...

BEIJING: China said Friday it supports a World Health Organization-led review into the global response to the coronavirus outbreak, but only “after the pandemic is over”.The comments from foreign ministry spokeswoman Hua Chunying came as China faces increasing global pressure to allow...

RAWALPINDI: US Special Representative for Afghan Reconciliation Zalmay Khalilzad Friday called on Chief of Army Staff General Qamar Javed Bajwa here on Friday. During the meeting, issues of mutual interest and overall regional security situation, including Afghan reconciliation process, came...

RAWALPINDI: US Special Representative for Afghan Reconciliation Zalmay Khalilzad Friday called on Chief of Army Staff General Qamar Javed Bajwa here on Friday.During the meeting, issues of mutual interest and overall regional security situation, including Afghan reconciliation process, came under...

RAWALPINDI: US Special Representative for Afghan Reconciliation Zalmay Khalilzad Friday called on Chief of Army Staff General Qamar Javed Bajwa here on Friday.During the meeting, issues of mutual interest and overall regional security situation, including Afghan reconciliation process, came under...

RAWALPINDI: Chief of Army Staff Gen Qamar Javed Bajwa said Pakistan’s support towards Afghan peace is a manifestation of “our goodwill to the cause” in a meeting with US Special Representative for Afghan Reconciliation Zalmay Khalilzad.According to a press release issued by the...

Many workers will be displaced and many businesses will close as a result of the slowdown caused by COVID-19. Providing support to those affected gives them a fighting chance.

For many of Indonesia’s urban poor who work in the informal sector, social distancing is nearly impossible if they want to maintain their income. Two key policies can help.

The production processes and supply chains that feed into the production of masks, gloves and other personal protective equipment must be secured.

The United States is rallying support to back Taiwan's observer status in the World Health Assembly, the decision-making body of the World Health Organization, leading into its annual meeting May 17-21."Today, I want to call on all nations, including those in Europe, to support Taiwan's participatio...

The newly launched ‘1093 helpline service’ of the Sindh Local Government Department has been providing counselling service to around 50 people on a daily basis who are suffering from various psychological issues due to the ongoing coronavirus crisis in the country, said Sindh Local...

The Sindh High Court on Friday issued notices to the federal and provincial law ministries on a petition of the Sindh Bar Council seeking direction to the federal and Sindh governments for the provision of an annual grant in aid to the lawyers’ top provincial regulatory body and at least...

Loan agreements outline the terms of an agreement for a loan. This document dated 6 May 2020 is provided for the ADB project 54183-001 in Bhutan.

ADB President Masatsugu Asakawa and Bangladesh Finance Minister and ADB Governor A H M Mustafa Kamal today discussed ADB’s support to Bangladesh in its fight against the novel coronavirus disease (COVID-19) pandemic.

ADB has approved a $1.5 billion loan to help the Philippine government fund its novel coronavirus disease (COVID-19) response program and strengthen the country’s health care system in its fight against the pandemic.

ADB President Masatsugu Asakawa and Pakistan’s Federal Minister for Economic Affairs and ADB Governor Makhdoom Khusro Bukhtiar today discussed how ADB can scale up its support for the government’s response to the COVID-19...

ADB today approved a $200 million loan to support the Philippine government’s effort to provide emergency cash subsidies to vulnerable households amid the novel coronavirus disease (COVID-19) pandemic.

ADB today approved a $1.5 billion loan to the Government of India to help fund its response to the COVID-19 pandemic, including support for immediate priorities such as disease containment and prevention, as well as social...

ADB President Masatsugu Asakawa and Nepal Finance Minister and ADB Governor Yuba Raj Khatiwada today discussed ADB’s support to Nepal in its fight against the novel coronavirus disease (COVID-19) pandemic.

ADB today approved a $100 million loan to support the Government of Bangladesh in its efforts to address the immediate public health requirements of combatting the novel coronavirus disease (COVID-19) pandemic.

ADB has provided several targeted interventions to support its developing member countries in combating the effects of the COVID-19 pandemic from its early stages. In support of ADB’s effort, the Government of Japan is...

ADB today approved a $20 million loan to support Bhutan’s efforts to stimulate the economy, protect public health, and mitigate the effects of the novel coronavirus disease (COVID-19) pandemic on its people.

The Asian Development Bank (ADB) has provided a guarantee for a $25 million trade loan to the State Pharmaceuticals Corporation of Sri Lanka (SPC) to purchase medical supplies as part of the country’s response to the novel ....

The program aimed to increase the role of women entrepreneurs in economic development and address constraints they and micro, small, and medium-sized enterprises (MSMEs) faced. The program had two components—a policy-based loan (PBL) and a financial intermediation loan (FIL) — each at $20.0 million. The program was supported by a technical assistance (TA) capacity building component of $0.6 million.

Transport systems provide arteries for efficient movement of people and goods in a well-functioning economy. The Asia and Pacific region has witnessed brisk economic growth and social development leading to increased mobility and urbanization. Rapid growth and urbanization creates pressure on transport system and services, which need to keep up not only to sustain the economic growth, but also to ensure much needed equitable access and quality services for all sections of the society.

ADB's support to Asia and the Pacific’s transport sector has helped improve domestic connectivity and economic efficiency in the region, says a report released by ADB’s Independent Evaluation Department.

Approved project 54061-001 in Sri Lanka.

Approved project 43407-017 in Philippines.

Approved project 42466-018 in Bangladesh.

Approved project 54169-001 in Kyrgyz Republic.

Approved project 54183-001 in Bhutan.

Approved project 54180-001 in Bangladesh.

All over the world, people and societies are adjusting to social distancing and a long-term work-from-home environment. Students and teachers too are now adapting to virtual classes, quickly mastering and equipping themselves with all tools necessary to...

The leaders of U.S. congressional foreign affairs committees wrote to nearly 60 countries on Friday asking them to support Taiwan's participation in the World Health Organization, citing the need for the broadest effort possible to fight the coronavirus pandemic.

Title: Health Tip: Support Your Back While Sitting
Category: Health News
Created: 4/30/2013 8:35:00 AM
Last Editorial Review: 4/30/2013 12:00:00 AM

Title: Study Supports Broader Access to Lap-Band Weight-Loss Surgery
Category: Health News
Created: 5/2/2013 10:35:00 AM
Last Editorial Review: 5/2/2013 12:00:00 AM

Title: Early Emotional Support May Help Kids Manage Feelings Later
Category: Health News
Created: 4/26/2016 12:00:00 AM
Last Editorial Review: 4/27/2016 12:00:00 AM

Title: Strong Support for NIH in New Budget From Congress
Category: Health News
Created: 5/2/2017 12:00:00 AM
Last Editorial Review: 5/3/2017 12:00:00 AM

Title: Loving, Supportive Kids May Help Lower Seniors' Dementia Risk
Category: Health News
Created: 5/2/2017 12:00:00 AM
Last Editorial Review: 5/3/2017 12:00:00 AM

Title: Most U.S. Adults Support More Mental Health Services for Kids
Category: Health News
Created: 5/1/2018 12:00:00 AM
Last Editorial Review: 5/2/2018 12:00:00 AM

Title: Study Supports Radiation for Early, Hormone-Driven Breast Cancer
Category: Health News
Created: 4/26/2019 12:00:00 AM
Last Editorial Review: 4/29/2019 12:00:00 AM

Machine-readability of scholarly outputs is critical to supporting large-scale analysis of the scientific literature. To that end, PMC’s Tagging Guidelines and internal processes have been updated to support the JATS4R recommendations for tagging clinical trial information. NLM encourages PMC-participating publishers, journals, and data providers to review this guidance. Please contact us at pubmedcentral@ncbi.nlm.nih.gov if you have any questions.

ABSTRACT

Over the last decade, innate immune priming has been evidenced in many invertebrate phyla. If mechanistic models have been proposed, molecular studies aiming to substantiate these models have remained scarce. We reveal here the transcriptional signature associated with immune priming in the oyster Crassostrea gigas. Oysters were fully protected against Ostreid herpesvirus 1 (OsHV-1), a major oyster pathogen, after priming with poly(I·C), which mimics viral double-stranded RNA. Global analysis through RNA sequencing of oyster and viral genes after immune priming and viral infection revealed that poly(I·C) induces a strong antiviral response that impairs OsHV-1 replication. Protection is based on a sustained upregulation of immune genes, notably genes involved in the interferon pathway and apoptosis, which control subsequent viral infection. This persistent antiviral alert state remains active over 4 months and supports antiviral protection in the long term. This acquired resistance mechanism reinforces the molecular foundations of the sustained response model of immune priming. It further opens the way to applications (pseudovaccination) to cope with a recurrent disease that causes dramatic economic losses in the shellfish farming industry worldwide.

IMPORTANCE In the last decade, important discoveries have shown that resistance to reinfection can be achieved without a functional adaptive immune system, introducing the concept of innate immune memory in invertebrates. However, this field has been constrained by the limited number of molecular mechanisms evidenced to support these phenomena. Taking advantage of an invertebrate species, the Pacific oyster (Crassostrea gigas), in which we evidenced one of the longest and most effective periods of protection against viral infection observed in an invertebrate, we provide the first comprehensive transcriptomic analysis of antiviral innate immune priming. We show that priming with poly(I·C) induced a massive upregulation of immune-related genes, which control subsequent viral infection, and it was maintained for over 4 months after priming. This acquired resistant mechanism reinforces the molecular foundations of the sustained response model of immune priming. It opens the way to pseudovaccination to prevent the recurrent diseases that currently afflict economically or ecologically important invertebrates.

As the technical ability for genetic diagnosis continues to improve, an increasing number of diagnoses are made in infancy or as early as the neonatal period. Many of these diagnoses are known to be associated with developmental delay and intellectual disability, features that would not be clinically detectable at the time of diagnosis. Others may be associated with cognitive impairment, but the incidence and severity are yet to be fully described. These neonates and infants with genetic diagnoses therefore represent an emerging group of patients who are at high risk for neurodevelopmental disabilities. Although there are well-established developmental supports for high-risk infants, particularly preterm infants, after discharge from the NICU, programs specifically for infants with genetic diagnoses are rare. And although previous research has demonstrated the positive effect of early developmental interventions on outcomes among preterm infants, the impact of such supports for infants with genetic disorders who may be born term, remains to be understood. We therefore review the literature regarding existing developmental assessment and intervention approaches for children with genetic disorders, evaluating these in the context of current developmental supports postdischarge for preterm infants. Further research into the role of developmental support programs for early assessment and intervention in high-risk neonates diagnosed with rare genetic disorders is needed.

Background:

Facilitation is an effective approach for helping practices implement sustainable evidence-based practice improvements. Few studies examine the facilitation infrastructure and support needed for large-scale dissemination and implementation initiatives.

Wael Salem, Benjamin Cellini, Mark A. Frye, and Jean-Michel Mongeau

Most animals shift gaze by a ‘fixate and saccade’ strategy, where the fixation phase stabilizes background motion. A logical prerequisite for robust detection and tracking of moving foreground objects, therefore, is to suppress the perception of background motion. In a virtual reality magnetic tether system enabling free yaw movement, Drosophila implemented a fixate and saccade strategy in the presence of a static panorama. When the spatial wavelength of a vertical grating was below the Nyquist wavelength of the compound eyes, flies drifted continuously­ and gaze could not be maintained at a single location. Because the drift occurs from a motionless stimulus—thus any perceived motion stimuli are generated by the fly itself—it is illusory, driven by perceptual aliasing. Notably, the drift speed was significantly faster than under a uniform panorama suggesting perceptual enhancement due to aliasing. Under the same visual conditions in a rigid tether paradigm, wing steering responses to the unresolvable static panorama were not distinguishable from a resolvable static pattern, suggesting visual aliasing is induced by ego motion. We hypothesized that obstructing the control of gaze fixation also disrupts detection and tracking of objects. Using the illusory motion stimulus, we show that magnetically tethered Drosophila track objects robustly in flight even when gaze is not fixated as flies continuously drift. Taken together, our study provides further support for parallel visual motion processing and reveals the critical influence of body motion on visuomotor processing. Motion illusions can reveal important shared principles of information processing across taxa.

Respiratory support of the critically ill neonate has steadily shifted from invasive to noninvasive forms of support. There have recently been a number of important advances in our understanding of the changes to neonatal resuscitation practices as they pertain to clinically important outcomes, mechanisms of gas exchange for high-flow nasal cannula, and best use of noninvasive ventilation and predicting response. Although the proportion of infants requiring intubation and mechanical ventilation has decreased, the most severely ill often still require intubation and ventilation. Recently, volume-targeted ventilation, high-frequency ventilation, and different methods of assessing weaning and extubation have been investigated. This review summarizes a number of important advances that have been made in the management of prematurity and neonatal respiratory distress syndrome.