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Multi-well sample plate cover penetration system

An apparatus for penetrating a cover over a multi-well sample plate containing at least one individual sample well includes a cutting head, a cutter extending from the cutting head, and a robot. The cutting head is connected to the robot wherein the robot moves the cutting head and cutter so that the cutter penetrates the cover over the multi-well sample plate providing access to the individual sample well. When the cutting head is moved downward the foil is pierced by the cutter that splits, opens, and folds the foil inward toward the well. The well is then open for sample aspiration but has been protected from cross contamination.




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Method and apparatus for inspecting defects of circuit patterns

The present invention relates to a defect inspection apparatus for inspecting defects in patterns formed on a semiconductor device, on the GUI of which for the confirmation of the inspection results an area is provided for displaying any one of or facing each other the features amount of defects, and the image during inspection or the reacquired image, and on the GUI of which a means is provided for setting the classification class and importance of the defects, and based on the classification class and the importance of the defects information set by this setting means, the classification conditions or the defect judging conditions are automatically or manually set so that the inspection conditions may be set easily.




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Tool selection method for machine tool, control device, and numerically controlled lathe

A tool selection method, for a machine tool, comprising the steps of identifying the maximum tip distance (D2) of a currently selected tool (141), a next designated tool (142) and an intermediate tool (143) disposed therebetween; moving a tool rest (10) in the +(plus)X-axis direction after a machining by the currently selected tool (141) is completed until the tip of the currently selected tool (141) is spaced from a workpiece (W) along the X-axis by a distance provided by adding a clearance distance (E) to a difference between the maximum tip distance (D2) and the tip distance (D3) of the currently selected tool (141); moving the tool rest (10) in the +(plus)Y-axis direction until the tip of the next designated tool (142) is aligned with the rotation center axis (12a) of the workpiece (W) in the X-axis direction; and moving the tool rest (10) in the −(minus)X-axis direction.




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Multiple punch and die assembly providing hand disassembly, punch length adjustment and replacement

A multiple punch and multiple die assembly has a workpiece protector as a punch lifter that is operatively associated with each punch for supporting each of the punches in an inactive position as an active punch is moved by the ram to the active, i.e. operating position to thereby eliminate scoring or marking of the sheet material or other workpiece that is being punched. To eliminate the need for hand tools and hand assembly or disassembly, a manually moveable retainer on the punch assembly is provided that can be moved by hand between a punch-releasing and punch-retaining position for holding the punches within the multi-punch assembly during operation. To prevent stress fractures that formerly occurred in die carriers, support of each die is distributed between two different die components thereby reducing impact stress on the carrier as the ram drives the punch through the workpiece.




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Punch device with interchangeable punch and variable punch pattern

A selection plate (39) is provided on a punch device (1) for activating or deactivating individual punch holding bars (13, 14). The plate has a coupling device (40) associated with a positive-locking coupling between a punch holding bar (13, 14) and the selection plate (39). Associated with the positive-locking coupling is an edge of the selection plate (39), that is provided with a recess (42), an extension (43) of the punch holding bar (13, 14) that extends around said edge, and/or a rib (41), which is located on the underside of the selection plate (39) and is associated with the punch holding bar (13, 14). As a result, it is possible to selectively establish or eliminate a positive-locking connection between the punch holding bar (13, 14) and the selection plate (39). Via the rib (41), the punch stroke of the selection plate (39) is merely transmitted to the punch holding bar (13 or 14), which is in positive-locking engagement with the lateral edge or the projections of the selection plate (39). The elongated rib (41) covers the heads (26, 27, 28, 29) of the punches (8) and transmits the stroke in a planar manner to the punch holding bar (13 or 14).




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Drug-transfer device, drug-delivery system incorporating the same, methods of fabricating the same, and methods of enabling administration of a drug

Devices capable of deterring or preventing bulk extraction of drugs from, for example, drug-delivery systems are exemplarily disclosed. In one embodiment, such a device may include a package releasably retaining a drug and an agent. The agent is configured to suppress a physiological effect of the drug when the agent contacts the drug or is coadministered with the drug. The cell package is configured such that an amount of the drug is selectively releasable with respect to the agent when the package is operably proximate to an encoded key. The package, however, may be configured to impose a relatively high likelihood that either the drug will not be accessed or the drug will be contaminated by the agent if access to the contents of the package is sought without the use of an encoded key.




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Drug-transfer device, drug-delivery system incorporating the same, methods of fabricating the same, and methods of enabling administration of a drug

A method of enabling administration of a drug includes determining, within a drug-transfer device including cells, a location of at least one cell and generating information identifying the determined location. A user may be provided with the drug-transfer device. The drug is retained within the at least one cell when the user is provided with the drug-transfer device. The method also includes encoding a key with the information and providing the user with the key before, after or when the user is provided with the drug-transfer device. Drug retained within the at least one cell is selectively releasable when the key is operably proximate to the drug-transfer device and is encoded with the information. The key can be encoded with the information before and/or after being provided to the user. In some embodiments, the key is encoded based on instructions transmitted over a network.




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Verification of a portable consumer device in an offline environment

A portable consumer device includes a base, and a computer readable medium on the base. The computer readable medium comprises code for an issuer verification value and a supplemental verification value. The issuer verification value is used by an issuer to verify that the portable consumer device is authentic in an on-line transaction and the supplemental verification value is used to verify that the portable consumer device is authentic in an off-line transaction.




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Multi-dimensional print cutting head

An apparatus and article for cutting print media associated with a printing process. A media cutting logic-controlled head is incorporated into printing hardware. The cutting head is provided with a plurality of cutting devices that may be implemented in the form of cutting pins. Control logic is provided to individually control an extension or actuation of each of the cutting devices. Multiple cutting devices may be simultaneously extended and retracted or activated and deactivated, to cut the media at multiple locations. The cutting head can be integrated with any of existing printers transforming a printer into a media cutting device capable of cutting two-dimensional complex shapes at the full line speed without requiring change in speed or reversal of the media at any point.




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Multiple punch and die assembly providing hand disassembly, punch length adjustment and replacement

A multiple punch and multiple die assembly has a workpiece protector as a punch lifter that is operatively associated with each punch for supporting each of the punches in an inactive position as an active punch is moved by the ram to the active, i.e. operating position to thereby eliminate scoring or marking of the sheet material or other workpiece that is being punched. To eliminate the need for hand tools and hand assembly or disassembly, a manually moveable retainer on the punch assembly is provided that can be moved by hand between a punch-releasing and punch-retaining position for holding the punches within the multi-punch assembly during operation. To prevent stress fractures that formerly occurred in die carriers, support of each die is distributed between two different die components thereby reducing impact stress on the carrier as the ram drives the punch through the workpiece.




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Verification of a portable consumer device in an offline environment

A portable consumer device includes a base, and a computer readable medium on the base. The computer readable medium comprises code for an issuer verification value and a supplemental verification value. The issuer verification value is used by an issuer to verify that the portable consumer device is authentic in an on-line transaction and the supplemental verification value is used to verify that the portable consumer device is authentic in an off-line transaction.




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Blanking die with device for replacing at least one punch

A sheet metal blanking die has a lower and an upper part and guide columns for maintaining the parts aligned. The upper part presents a plurality of punches which project downwards from it, when the die is closed by a press. Recesses are present on the flat lower portion to receive the respective punches at the moment of blanking. For one punch a rapid replacement device can be provided, including a chamber within which a loader can move presenting two cavities of vertical axis to receive relative punches. By moving the loader a punch can be selected for transfer from a rest position to an operative blanking position.




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Method and system for mass production of variable shaped products

A computerized system, method, and computer-readable media implementing a method for mass producing variable shaped printed products is presented. A set of cutlines defining a shape for the ordered item is associated with each ordered item. A ganging system selects a plurality of ordered items to be simultaneously produced. Individual cutter-ready outline files corresponding to the associated set of outlines for each of the items selected for production are rendered and inserted into a gang template to generate an aggregated cutlines gang file. The gang file and at least one sheet of substrate are submitted to a cutting system. The cutting system cuts the individual finished products from the substrate sheet(s).




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Switchable hole punch apparatus

An apparatus for punching holes is provided. The apparatus may include a base movable from a first position to a second position and first and second punch assemblies attached to and movable with the base. The punch assemblies may each include parallel punches movable relative to the base and having an end. The apparatus may include first and second cams fixed to a rotatable shaft and having an engagement portion for engagement with the ends of the respective punches at a predetermined rotation position of the shaft. When the base is in the first position, rotation of the shaft to the predetermined rotation position may cause movement of only one of the punches relative to the base. When the base is in the second position, rotation of the shaft to the predetermined rotation position may cause movement of only the other punch of the punch assemblies.




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Method and an apparatus for performing a program controlled process on a component

A drilling machine drills at a multiplicity of target locations on a component. Two robots, calibrated with calibration data, move the component in a 6-D coordinate system. A metrology system ascertains the position of the component relative to the drilling machine. The movement of the robots is effected by commands generated by off-line programming. The component is moved relative to the drilling machine to a target position, ready for drilling, by a closed-loop process in which the differences in position between the expected position (the target position) and the actual position (as viewed by the metrology system) are corrected.




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Punch assembly with quick attach punch point and stripper plate removably secure thereon

A punch assembly for a turret punch press having a two piece reciprocally movable punch member that has a punch point insert removably attached to a punch driver that allows replacement of the punch point insert without the need to extract the punch member from its punch guide. A locking assembly having four vertical guideways containing slider strips for coupling the punch point insert to the punch driver ensures precision registration of the punch point insert with its driver.




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Preservation of the biological activity of undenatured type II collagen

The instant invention is the storage of Type II collagen containing tissue in carbonated water. Such Type II collagen is useful for alleviating the symptoms of arthritis in mammals as well as the treatment of arthritis in mammals. Such Type II collagen is also useful for the prevention of arthritis in mammals. The instant invention is also a method for the preparation of a nutritional supplement that includes the steps of: (a) separating water-insoluble undenatured Type II collagen containing animal tissue from animal tissue not containing Type II collagen; (b) subdividing and sterilizing said tissue under conditions which do not change the original structure of the Type II collagen to produce a subdivided and sterilized product; (c) packaging the subdivided and sterilized product in carbonated water.




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Use of a polyamine-poor composition for the production of a medical human food

The disclosure relates to a novel use of a food composition for human use, having fewer than 1600 picomoles of polyamines, for the production of a medical food which is intended to combat a syndrome or pathology involving N-methyl-D-aspartate receptor subunit NR2-B.




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Sweetener compositions

The invention provides a sweetener composition comprising a combination of cellulose and a sweetener carbohydrate formed from a combination of at least two carbohydrates selected from the group consisting of sucrose, glucose and fructose, and a method for the preparation thereof.




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Mass distribution device and molding device

The present invention relates to an mass distribution device for supplying a mass of foodstuff starting material to one or more cavities of a mold drum for molding products from the mass, comprising a base member which extends partially around the outer cylindrical circumference of the drum and which has an introduction area through which the mass is the fed to the cavities. The invention further relates to a molding device and to a process for operating the inventive mass distribution device.




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Methods for producing multiple food extrudates

An apparatus for forming a single extrudable food stream such as a cooked cereal dough into a plurality of differently colored and/or flavored dough streams is disclosed including an extruder having screw augers for advancing a plastic food mass, a head or manifold for dividing the plastic food mass into a plurality of substreams each in turn in fluid communication with a plurality of sub-divided dough passageways, and a die head having a plurality of die ports. Each subpassage is separately supplied an additive and has disposed therein a multiplicity of in-line static mixer elements to admix the additive into the substreams of the plastic food mass before passage through the die ports. In a preferred form, first and second substreams are intermixed in a non-homogenous manner before reaching the exit ports. The extrudates are severed into individual pieces by a rotary cutter.




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Gum manufacturing system with loafing and conditioning features

Gum manufacturing machinery and method of manufacturing gum is illustrated in which a gum loafing machine generates loaves of finished gum that are then subsequently run through a gum conditioner to more uniformly set the temperature and viscosity of the gum material prior to further processing. Upon achieving the appropriate conditioning level, a further forming extruder may be used to generate a continuous gum ribbon for subsequent rolling and scoring operations. The gum conditioner may include vertically stacked conveyors that have different operational modes including a first mode that provides a serpentine path for a long residence time and a second mode that provides a cascading path that avoids or bypasses much of the length of some of the conveyors to provide a shorter residence time. The gum manufacturing machinery may be used in an adjustable manner so as to accommodate difference gum recipes for different batches of gum product.




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Method for production of an alcoholic beverage with reduced content of alcohol

A method for production of an alcoholic beverage with reduced content of alcohol involving treating unfermented beverage starting solution with glucose oxidase and glucose isomerase.




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Production of cottage cheese by using Streptococcus thermophilus

A method for producing cottage cheese by using Streptococcus thermophilus bacteria.




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Universal and restrictive enclosures for safely repressurizing sparkling wines and other carbonated beverage

The present disclosure is related to illustrative embodiments of an apparatus and method for maintaining carbonation of sparkling beverages, such as sparkling wines, cocktails, and non-alcoholic beverages such as sodas and coffee. A transparent, shatter-resistant, height-adjustable carbonation enclosure is used to contain an opened bottle of a sparkling beverage. An air-tight carbonation cap with a built-in one-way valve is used to re-carbonate the beverage inside the bottle using a pressurized gas source. The base of the carbonation enclosure includes a platform that may be used to adjust the effective height of the enclosure to fit the height of the bottle and provide an air-tight interface between an opening of the bottle and the carbonation cap. The carbonation enclosure further includes a number of openings to open air to prevent pressurization of the carbonation enclosure. Another illustrative embodiment includes a safety enclosure for multiple bottles pressurized directly by conical nozzles.




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Absorbent food pad and method of using same

The present invention provides a food preservation system that includes an absorbent food pad that has absorbent material to absorb exuded liquids from a food product, and has an oxygen scavenging system to modify the atmosphere in the food package. Also described is a method of using the absorbent food pad to enhance appearance of the food product and extend shelf life.




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Puffed oat based breakfast cereal of enhanced salty flavor perception and method of preparation

Methods of preparation and improved oat based puffed R-T-E or breakfast cereal products resulting there from with reduced sodium levels that provide good cooked grain flavor relative to other low or no sodium cooked cereal products and that approach the quality of higher sodium level products are provided. The methods include formulating cooked cereal doughs with minimal levels of sodium chloride and including a blend of potassium chloride and choline chloride. The cooked cereal dough is formed into pellets and gun puffed to form puff products having a total pyrazine content of at least 200 ppm. The puffed products are topically coated with saline solution and dried to provide the present improved low sodium high flavor finished breakfast cereal products.




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Method for producing bread from aerated dough

The components of the dough recipe are mixed in a dough mixing apparatus (2). The resulting dough is divided into portions, each of which is aerated to produce aerated dough. Mixing and aerating are performed by separate devices. Aeration is performed at a pressure no less than 0.3 MPa, and the pressure is then reduced to atmospheric at a controlled rate of 0.02-0.2 MPa/s. The lowering of pressure to atmospheric occurs either before or after the removal of the aeration device (6) from the dough. The aeration process is performed in baking molds (1), or in intermediate vessels (16), and the dough is subsequently transferred to the molds (1). The transfer occurs either into the molds (1) under atmospheric pressure, after lowering the pressure in the intermediate vessels (16) to atmospheric, or into the molds (1) under increased pressure, where the pressure is decreased to atmospheric after the transfer is completed. The claimed invention simplifies and increases the accuracy of dividing the dough into portions of a specified weight, enhances the quality of the aerated dough, reduces energy consumption and increases production efficiency.




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Method of preparing soybean mixed powder, method of preparing a solidified soybean food, and a method of preparing a packaged raw material for preparing a solidified soybean food

A method of preparing soybean mixed powder comprising a soybean powder having properties wherein formation of agglomerate is small when the powder is added to water and then heated with stirring to dissolve the powder.




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Process for reducing oil and fat in cooked food with pea protein

A process for cooking a food in oil and/or fat is provided. A dry pea protein mixture or an aqueous pea protein is added to a food prior to cooking. The amount of oil and/or fat absorbed by the food during cooking is substantially reduced.




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Sweetener compositions

The invention provides a sweetener composition comprising a combination of cellulose and a sweetener carbohydrate formed from a combination of at least two carbohydrates selected from the group consisting of sucrose, glucose and fructose, and a method for the preparation thereof.




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Omega-3 enriched fish oil-in-water parenteral nutrition emulsions

An emulsion is provided including: an oil component and a water component, the oil component including: fish oil triglycerides in an amount of about 60% to about 90% based on the weight of the oil component; wherein the fish oil triglycerides include omega-3 fatty acids, expressed as triglycerides, in an amount of at least 60%, based on the total weight of the fatty acids of the fish oil triglycerides; wherein the fish oil triglycerides include a total amount of EPA and DHA, expressed as triglycerides, of at least 45%, based on the total weight of the fatty acids of the fish oil triglycerides; and, at least one medium-chain triglyceride, wherein a total amount of the at least one medium-chain triglyceride is from about 10% to about 40% based on the weight of the oil component.




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Protein hydrolysate compositions having improved sensory characteristics and physical properties

The present invention provides protein hydrolysate compositions, processes for making protein hydrolysate compositions, and food products comprising protein hydrolysate compositions. The protein hydrolysate compositions generally comprise polypeptide fragments having primarily either an arginine residue or a lysine residue at each carboxyl terminus.




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Yeast extract containing γ-Glu-X or γ-Glu-X-Gly and a method for producing the same

A yeast extract containing a peptide, such as γ-Glu-X and γ-Glu-X-Gly, wherein X can represent an amino acid or an amino acid derivative other than Cys and derivatives thereof, is prepared by culturing a yeast in a medium containing a peptide such as γ-Glu-X, γ-Glu-X-Gly and X-Gly, and preparing a yeast extract from the obtained cells.




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Combinations of atmosphere control members

Combinations of atmosphere control members are used to control the atmosphere within a sealed container which contains a respiring biological material. The combination makes use of a first ACM having a first R ratio (the ratio of carbon dioxide permeability to oxygen permeability) and a second ACM having a second R ratio, the first R ratio being substantially greater than 1.0, and the second R ratio being less than the first R ratio. This combination (31, 321, 322, 331, 332) can form part of the sealed container (1) itself, or can be part of an assembly (31, 32, 34) through which the packaging atmosphere within the sealed container (1) is circulated.




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Preserving seasoning flavour profiles during the manufacturing of food-seasoning sheets

A method and an installation are provided for preserving desired seasoning flavour profiles during the manufacturing of food-seasoning sheets. The method includes the steps of; laying a thin layer of adhesive on a base sheet; removing air from the adhesive prior to the step of laying; reducing free moisture from the adhesive during the step of laying, and depositing food-seasoning ingredients onto the thin layer of adhesive. The installation for manufacturing food-seasoning sheets includes an adhesive dispenser having a reservoir and a delivery slot communicating with the reservoir for dispensing adhesive. The dispenser has a heating element mounted thereto for heating the adhesive. The adhesive is made under a partial vacuum and it is conveyed to the dispenser in a partial vacuum.




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Method and system for treating food items with an additive and solid carbon dioxide

Embodiments of the invention generally provide methods and systems that distribute an additive in solid carbon dioxide in an interior of food processing equipment. The additive may be injected into a flow of liquid carbon dioxide upstream of an expander at or adjacent to the interior. Injection of the additive into the interior may be alternated with directing a flow of expanded carbon dioxide into the interior. In some embodiments, the freezing point of the additive with or without a diluent composition and/or additive(s) is lower than a temperature of the liquid carbon dioxide.




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Flavoring substance-included cellulose

The present invention concerns a flavoring substance-included cellulose, comprising or consisting of cellulose and flavoring substances included in the cellulose, methods for producing such flavoring substance-included celluloses, and mixtures comprising flavoring substance according to the invention.




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Whole green coffee bean products and methods of production and use

Disclosed are novel processing methods for green coffee beans that result in novel green coffee bean products, including products that incorporate whole green coffee beans. Methods include selecting whole coffee beans in their fresh green unroasted state with naturally-occurring levels of phytonutrients, sterilizing and drying them, applying iterative grinding processes and stabilization techniques, all while avoiding high temperatures. Whole green coffee bean products created and defined by these methods have unexpectedly been found to increase focus and concentration in users, and are believed useful in the treatment of attention and concentration deficits and related disorders, such as attention deficit (AD), attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), and various related and/or comorbid disorders.




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Methods of preparing no bake granola product

The invention generally provides novel no-bake grain products and methods of preparation of the same. Specifically a no-bake food product with a toasted appearance and flavor and a method of providing a toasted appearance and flavor to a no-bake food product. The no-bake food product includes granola bars, clusters, cereal, instant hot cereal and snacks.




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Wheat protein and methods of production

Isolated wheat proteins that are substantially free of sulfites and compositions formed from the isolated wheat proteins are described. Methods of forming compositions which include isolated wheat proteins that are substantially free of sulfites are also described.




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6'-sialyllactose salts and process for their synthesis and for the synthesis of other alpha-sialyloligosaccharides

The present invention relates to a process of synthesis of α-sialyl oligosaccharides and in particular of 6'-sialyllactose and its salts comprising a step of coupling by Koenigs-Knorr reaction under conditions that allow its use on an industrial scale.




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Method to develop high oleic acid soybeans using conventional soybean breeding techniques

The present invention is directed to a soybean plant with mutations in FAD2-1A and FAD2-1B. Moreover, the present invention is directed to seeds from said plants with altered ratios of monosaturated and polyunsaturated fats. In particular, the present invention is directed to plants where the plants exhibit elevated levels of oleic acid.




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Maize variety hybrid X80B470

A novel maize variety designated X80B470 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X80B470 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X80B470 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X80B470, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X80B470. This invention further relates to methods for producing maize varieties derived from maize variety X80B470.




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Method of increasing lean body mass and reducing body fat mass in infants

Disclosed is a method of increasing lean body mass and reducing fat body mass in infants, said method comprising administration to an infant, term or preterm, a nutritional formula comprising a source of DHA and ARA. It has been found that the administration of DHA and ARA, or a source thereof, in infants can increase lean body mass and reduce fat body mass, when compared to an unsupplemented control formula, without impacting the total overall growth of the infant. This method is especially useful in preterm infants.




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Method for making a high-protein dairy product

A dairy-based yogurt product having a protein level above 15%, sometimes more than 25%, with a smooth and rich texture and no grittiness. The yogurt product includes a particular selection of dairy proteins and other ingredients to raise the gelation temperature of the dairy proteins and avoid causing gelation or precipitation during pasteurization. Additionally, pasteurization temperatures, times and methods are selected to avoid gelation. Starting dairy proteins generally have relatively higher pH levels and low total acidity (TA) levels to help reduce gelation during pasteurization. Ingredients such as buffering agents and sequestering agents may be utilized to help raise the gelation temperature, as well as higher sugar levels which can control hydration of the proteins.




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Cross-linked biopolymers, related compositions and methods of use

The present invention provides stabilized oil-in-water emulsions with an extended range of chemical, thermal and/or mechanical stabilities, and method(s) for their preparation. Such preparations provide an environmentally-protective biopolymer component exhibiting improved adherence to the dispersed phase, reducing or eliminating dissociation therefrom under such conditions, for use in the context of a range of food, pharmaceutical, personal care, health care, cosmetic and other end-use applications.




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Shortening particle compositions and dough products made therefrom

The invention relates to shortening particle compositions that are suitable for use in preparing batter or dough products such as biscuits, pizza crusts, pot pie crusts, cinnamon rolls, or dry mixes for same. Typically, the shortening compositions are low in trans fatty acids and in saturated fatty acids. For example, the shortening particle composition may comprise less than about 3% wt. total trans fatty acids and a total of about less than about 61% wt. saturated fatty acids and trans fatty acids.




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Laccase for detoxification of feed products

The present invention relates to a method for detoxification of feed products contaminated by the mycotoxin zearalenone.




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Saccharification enzyme composition and method of saccharification thereof

The present disclosure relates to a Bacillus subtilis alpha-amylase (AmyE) or its variants thereof. AmyE or its variants thereof may be used to more efficiently produce fermentable sugars from starch. Also disclosed are a composition comprising a glucoamylase and AmyE or variant thereof and a method of processing starch utilizing the described enzyme composition.