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'Completely surprised to see him do a character like that so beautifully': Tammanna Bhatia on Hrithik's 'Super 30'

Actress Tamannaah Bhatia who has always been in awe of Hrithik, recently shared she was moved and inspired by his phenomenal acting in Super 30.




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Coronavirus impact: Now 33.5 mn seek unemployment benefits in US

The reports support many economists' belief that the economic slump could persist for a while




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Covid-19 impact: US unemployment rate surges to 14.7%, the worst since 1948

As the US lost over 20 million jobs in a pandemic-induced economic spiral during April, its unemployment rate zoomed to nearly 15 per cent




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Covid-19 impact: Mexico, Brazil see 99% plunge in auto production in April

In normal times, the combined number of cars produced by Mexico and Brazil every month is half a million




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Tesla ordered to keep US vehicle factory in Fremont closed amid lockdown

Elon Musk has said those employees who do not feel comfortable coming back to work are not obligated to do so




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Active Investing in the Age of Disruption


 

Outperforming the market—or “alpha creation” as it’s sometimes called—is very possible with the proper investment discipline and methodologies. But the market-beating strategies that will work today are not the same as those that worked in the past.

Central bank intervention and the accelerated pace of technology have caused an increase in the disruption of traditional business models across many industries. These industry paradigm shifts combined



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Asset Liability Management Optimisation: A Practitioner's Guide to Balance Sheet Management and Remodelling


 

An advanced method for financial institutions to optimize Asset Liability Management for maximized return and minimized risk

Financial institutions today are facing daunting regulatory and economic challenges. As they manage bank regulation and competition, institutions are also optimizing their Asset Liability Management (ALM) operations. The function of the ALM unit today goes beyond risk management related to the banking book into managing regulatory



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The burning actor rushes to his bubble bath

The key to every Daniel Day-Lewis performance was a big theme and a thousand details.And in the final phase of his acting career, says Sreehari Nair, America became his big theme, and the details... well, he just popped them out like waffles.






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Supplementation of nano-bubble curcumin extract improves gut microbiota composition and exercise performance in mice

Food Funct., 2020, 11,3574-3584
DOI: 10.1039/C9FO02487E, Paper
Yi-Ming Chen, Wan-Chun Chiu, Yen-Shuo Chiu, Tong Li, Hsin-Ching Sung, Chien-Yu Hsiao
NCE supplementation was able to modulate the gut microbiota increased the Lactobacillus genus.
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Bilberry anthocyanin extracts enhance anti-PD-L1 efficiency by modulating gut microbiota

Food Funct., 2020, 11,3180-3190
DOI: 10.1039/D0FO00255K, Paper
Luoyang Wang, Guoqiang Jiang, Nan Jing, Xuerun Liu, Qicheng Li, Wei Liang, Zheng Liu
Bilberry anthocyanin extracts change the gut microbiota and enhance the anti-tumor efficiency of the PD-L1 antibody.
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Vinegar extract ameliorates alcohol-induced liver damage associated with the modulation of gut microbiota in mice

Food Funct., 2020, 11,2898-2909
DOI: 10.1039/C9FO03015H, Paper
Ting Xia, Bo Zhang, Shaopeng Li, Bin Fang, Wenhui Duan, Jin Zhang, Jia Song, Min Wang
Vinegar extract inhibited alcohol-induced ROS generation and inflammation. Vinegar extract modulated gut microbiota and improved intestinal homeostasis, which could be used as a novel gut microbiota manipulator against alcohol-induced liver damage.
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Capsaicin—the major bioactive ingredient of chili peppers: bio-efficacy and delivery systems

Food Funct., 2020, 11,2848-2860
DOI: 10.1039/D0FO00351D, Review Article
Muwen Lu, Chengyu Chen, Yaqi Lan, Jie Xiao, Run Li, Junqing Huang, Qingrong Huang, Yong Cao, Chi-Tang Ho
The mechanisms of bio-efficacy of capsaicin and delivery systems with enhanced bioavailability were reviewed.
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Purification, characterization and molecular cloning of a dicaffeoylquinic acid-hydrolyzing esterase from human-derived Lactobacillus fermentum LF-12

Food Funct., 2020, 11,3235-3244
DOI: 10.1039/D0FO00029A, Paper
Yujin Liu, Minhao Xie, Peng Wan, Guijie Chen, Chunxu Chen, Dan Chen, Shijie Yu, Xiaoxiong Zeng, Yi Sun
Dicaffeoylquinic acids (DiCQAs), the main components of kudingcha made from the leaves of Ilex kudingcha, could be transformed by gut microbiota.
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The prophylactic effects of different Lactobacilli on collagen-induced arthritis in rats

Food Funct., 2020, 11,3681-3694
DOI: 10.1039/C9FO02556A, Paper
Zhexin Fan, Bo Yang, R. Paul Ross, Catherine Stanton, Jianxin Zhao, Hao Zhang, Wei Chen
The current study evaluated the prophylactic effects of different Lactobacillus species on arthritis induced by collagen.
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Oleacein inhibits STAT3, activates the apoptotic machinery, and exerts anti-metastatic effects in the SH-SY5Y human neuroblastoma cells

Food Funct., 2020, 11,3271-3279
DOI: 10.1039/D0FO00089B, Paper
Santa Cirmi, Marilena Celano, Giovanni Enrico Lombardo, Valentina Maggisano, Antonio Procopio, Diego Russo, Michele Navarra
The present findings demonstrate that oleacein, the main secoiridoid of extravirgin olive oil, acts against neuroblastoma cells, by reducing cell adhesion and migration, inducing apoptotic death and modulating STAT3-dependent pathway.
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Colonization and immunoregulation of Lactobacillus plantarum BF_15, a novel probiotic strain from the feces of breast-fed infants

Food Funct., 2020, 11,3156-3166
DOI: 10.1039/C9FO02745A, Paper
Na Zhang, Chen Li, Zhihua Niu, Hongyan Kang, Miaoshu Wang, Bo Zhang, Hongtao Tian
Immunosuppression is a manifestation imbalance in the immune system, often during unhealthy states.
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Integrated anti-hyperlipidemic bioactivity of whole Citrus grandis [L.] osbeck fruits—multi-action mechanism evidenced using animal and cell models

Food Funct., 2020, 11,2978-2996
DOI: 10.1039/C9FO02290B, Paper
Li-Yun Lin, Boa-Chan Huang, Kuan-Chou Chen, Robert Y. Peng
Multi- antihyperlipidemic mechanism revealed by the pomelo phytonutrients. Both the sterol synthesis and lipogenesis pathways are affected by the pomelo phytonutrients. Dotted line: from citation. Solid line: verified in this experiment.
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Addition of flavonols and polysaccharides as excipient ingredients into epicatechin rich green tea extract inhibited free radical formation and glucose uptake

Food Funct., 2020, 11,3105-3111
DOI: 10.1039/C9FO03020D, Paper
So-Hee Yoo, Yeong-Eun Lee, Jin-Oh Chung, Chan-Su Rha, Yong-Deog Hong, Mi-Young Park, Soon-Mi Shim
Results from the current study suggested that whole green tea components rich in flavonols and polysaccharides could be potential hypoglycemic excipient ingredients into green tea catechins by enhancing catechin absorption.
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Impact of functional foods and nutraceuticals on high blood pressure with a special focus on meta-analysis: review from a public health perspective

Food Funct., 2020, 11,2792-2804
DOI: 10.1039/D0FO00357C, Review Article
Kamesh Venkatakrishnan, Hui-Fang Chiu, Chin-Kun Wang
In recent times many researchers are expressing immense interest in nutraceuticals and functional foods for combating various diseases or abnormal conditions, especially against hypertension (HT).
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cis 9, trans 11, but not trans 10, cis 12 CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice through activation of GPR120-[Ca2+]i and the MLCK signaling pathway

Food Funct., 2020, 11,3657-3667
DOI: 10.1039/D0FO00376J, Paper
Han Su, Weijie Zhao, Fenglin Zhang, Min Song, Fangfang Liu, Jisong Zheng, Mingfa Ling, Xiaohua Yang, Qiang Yang, Haiwen He, Lin Chen, Xumin Lai, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
In vitro and in vivo studies show that c9, t11-CLA, but not t10, c12-CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice via activation of GPR120-[Ca2+]i and the MLCK pathway.
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Black mulberry ethanol extract attenuates atherosclerosis-related inflammatory factors and downregulates PPARγ and CD36 genes in experimental atherosclerotic rats

Food Funct., 2020, 11,2997-3005
DOI: 10.1039/C9FO02736J, Paper
Yun-Guo Liu, Jia-Li Yan, Yan-Qing Ji, Wen-Jing Nie, Yan Jiang
Atherosclerosis (AS) is the pathological basis of various vascular diseases and currently is seriously affecting human health.
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Dietary intake of Lycium ruthenicum Murray ethanol extract inhibits colonic inflammation in dextran sulfate sodium-induced murine experimental colitis

Food Funct., 2020, 11,2924-2937
DOI: 10.1039/D0FO00172D, Paper
Shuai Zong, Liu Yang, Hyun Jin Park, Jinglei Li
Lycium ruthenicum Murray extract protected experimental colitis by inhibiting pro-inflammatory cytokines production, inflammatory cell infiltration, inflammatory mediators activation and oxidative stress, and restored intestinal barrier integrity.
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Study of viability of high pressure extract from pomegranate peel to improve carrot juice characteristics

Food Funct., 2020, 11,3410-3419
DOI: 10.1039/C9FO02922B, Paper
João P. Trigo, Elisabete M. C. Alexandre, Sara Silva, Eduardo Costa, Jorge A. Saraiva, Manuela Pintado
Extracts from fruit processing by-products usually present high amounts of bioactive compounds with several important activities such as antioxidant and antimicrobial capacities.
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The impact of oligosaccharide content, glycosidic linkages and lactose content of galacto-oligosaccharides (GOS) on the expression of mucus-related genes in goblet cells

Food Funct., 2020, 11,3506-3515
DOI: 10.1039/D0FO00064G, Paper
Susana Figueroa-Lozano, Chengcheng Ren, Huifang Yin, Hien Pham, Sander van Leeuwen, Lubbert Dijkhuizen, Paul de Vos
Galacto-oligosaccharides (GOS) are molecules known to impact goblet cell function and mucus composition. Our results show that their molecular structure have a direct effect on goblet cells and impact mucus synthesis-related genes.
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Correction: 5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes

Food Funct., 2020, 11,3749-3749
DOI: 10.1039/D0FO90012E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jie Liu, Yu Wang, Yiming Hao, Zongwei Wang, Zihui Yang, Ziyuan Wang, Jing Wang
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Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

Food Funct., 2020, 11,3459-3470
DOI: 10.1039/C9FO02803J, Paper
Yina Huang, Liang Qiu, Xuan Mi, Zhihong Zhang, Di Xu, Xueying Tao, Keyu Xing, Qinglong Wu, Hua Wei
There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.
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Ergosterol peroxide from Pleurotus ferulae inhibits gastrointestinal tumor cell growth through induction of apoptosis via reactive oxygen species and endoplasmic reticulum stress

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02454A, Paper
Yi Yang, Xiaoyu Luo, Mayila Yasheng, Jun Zhao, Jinyu Li, Jinyao Li
Ergosterol peroxide was purified from Pleurotus ferulae by silica gel chromatography, Sephadex LH-20 chromatography and recrystallization and named as PFEP, which was identified by ESI-MS and NMR.
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Enzymatic hydrolysis of insect Alphitobius diaperinus towards the development of bioactive peptide hydrolysates

Food Funct., 2020, 11,3539-3548
DOI: 10.1039/D0FO00188K, Paper
Pedro Sousa, Sandra Borges, Manuela Pintado
Edible insects are a promising protein source for the future generation, due to their nutritional composition, sustainability and low environmental impact.
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A rapid protocol to distinguish between Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium based on the characteristic fingerprint and UHPLC-Q-TOF MS methods

Food Funct., 2020, 11,3719-3729
DOI: 10.1039/D0FO00082E, Paper
Liqiang Shi, Rongjin Wang, Tianshu Liu, Jiajie Wu, Hongxu Zhang, Zhiqiang Liu, Shu Liu, Zhongying Liu
Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium were successfully distinguished by the characteristic fingerprint and UHPLC-Q-TOF MS methods.
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Correction: Efficacy of proprietary Lactobacillus casei for anti-tuberculosis associated gastrointestinal adverse reactions in adult patients: a randomized, open-label, dose–response trial

Food Funct., 2020, 11,3751-3751
DOI: 10.1039/D0FO90017F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Song Lin, Shanliang Zhao, Jiahong Liu, Jianwen Zhang, Chao Zhang, Haibo Hao, Yuxia Sun, Jing Cai, Yang Yang, Yan Ma, Yuanyuan Li, Jinyu Wang, Aiguo Ma
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The purification, structural characterization and antidiabetic activity of a polysaccharide from Anoectochilus roxburghii

Food Funct., 2020, 11,3730-3740
DOI: 10.1039/C9FO00860H, Paper
Yuntao Liu, Tingting Tang, Songqi Duan, Cheng Li, Qinlu Lin, Hejun Wu, Aiping Liu, Bin Hu, Dingtao Wu, Suqing Li, Li Shen, Wenjuan Wu
Anoectochilus roxburghii, a traditional Chinese medicinal herb, has been widely used for treating numerous chronic diseases.
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Usage of supercritical fluid techniques to obtain bioactive alkaloid-rich extracts from cherimoya peel and leaves: extract profiles and their correlation with antioxidant properties and acetylcholinesterase and α-glucosidase inhibitory activities

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00342E, Paper
Oscar Galarce-Bustos, Mª Teresa Fernández-Ponce, Antonio Montes, Clara Pereyra, Lourdes Casas, Casimiro Mantell, Mario Aranda
The wastes generated by cherimoya cultivation and processing industries should be contemplated as a valuable source of bioactive alkaloids, with potential in pharmaceutical applications for the treatment or prevention of chronic diseases.
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Targets and Underlying Mechanisms for Sedative and Hypnotic Activities of Saponins from Semen Ziziphus jujube

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00098A, Paper
Chun-Yan Shen, Lin Wan, Jing-Jing Zhu, Jian-Guo Jiang
Semen Ziziphus jujube (SZJ) has been widely consumed as edible resources in China to treat insomnia disorders. However, the underlying mechanisms and potential therapeutic targets remained obscure. SZJ-I and SZJ-II...
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Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00427H, Paper
Xiao-Shan Long, Sen-Tai Liao, Peng Wen, Yu-Xiao Zou, Fan Liu, Wei-Zhi Shen, Teng-Gen Hu
Mulberry removed monosaccharides (FM) displayed better hypoglycemic activity than untreated mulberry (MP), which may be attributed the stronger effects of FM on activating PI3K/Akt and AMPK signaling pathways.
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Cytoprotective effects of a proprietary red maple leaf extract and its major polyphenol, ginnalin A, against hydrogen peroxide and methylglyoxal induced oxidative stress in human keratinocytes

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00359J, Paper
Chang Liu, Hao Guo, Joel A. Dain, Yinsheng Wan, Xing-Hua Gao, Hong-Duo Chen, Navindra P. Seeram, Hang Ma
Maplifa™ (a proprietary red maple leaves extract) and its major polyphenol, ginnalin A, exert skin protective effects against oxidative stress.
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Structural and physicochemical changes in almond milk during in vitro gastric digestion: impact on the delivery of protein and lipids

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02465D, Paper
Xin Wang, Aiqian Ye, Harjinder Singh
The gastric digestion of almond milk in a human gastric simulator resulted in major structural and physicochemical changes. The changes had significant impact on the rate of delivery of protein and lipids to the small intestine.
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Physicochemical and antibacterial properties of fabricated ovalbumin-carvacrol gel nanoparticles

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00755B, Paper
Shengqi Rao, Guang-wei Xu, Huawei Zeng, Xiang-feng Zheng, Qin Hu, Qi-Yan Wang, Zhenquan Yang, Xin'An Jiao
The applications of carvacrol are limited due to its poor stability, water solubility, and high volatility; however, ovalbumin can be used to encapsulate hydrophobic molecules, improve their aqueous solubility, and...
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Lactic acid bacteria alleviates polycystic ovarian syndrome by regulating sex hormone related gut microbiota

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02554E, Paper
Yufeng He, Qianqian Wang, Xiu Li, Gang Wang, Jianxin Zhao, Hao Zhang, Wei Chen
Polycystic ovarian syndrome (PCOS) is a common endocrine disease across the world. Because gut microbiota play a key role in the pathogenesis of PCOS, probiotics may alleviate PCOS symptoms through...
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The effect of quercetin on endothelial cells is modified by heterocellular interactions

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00141D, Paper
Open Access
Sarka Tumova, Michael J. Houghton, Gary Williamson
Single cell-type models are useful for determining mechanisms, but in vivo, cell–cell interactions are important, and neighbouring cells can impact endothelial cell function.
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Enzyme reaction-guided identification of active components from the flowers of Sophora japonica var. violacea

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00625D, Paper
Yunci Zhang, Dongyu Gu, Shuai He, Jing Meng, Jifeng Wang, Yunxiao Wang, Yi Wang, Jing Tian, Yi Yang
The flower of S. japonica is a favorite food and used as traditional medicine.
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The Ameliorative Effect of Lactobacillus plantarum-12 on DSS-induced murine colitis

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00007H, Paper
MengYing Sun, YuJun Liu, Yinglong Song, Yuan Gao, Fujunzhu Zhao, Yanghe Luo, Fang Qian, Guangqing Mu, Yanfeng Tuo
Some lactobacilli strains can exert beneficial effects on host when ingested in an adequate dose, such as immunoregulation and anti-inflammatory activities. In this study, the survival abilities in simulated gastrointestinal...
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Sugar matters: sugar moieties as reactivity-tuning factors in quercetin O-glycosides

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00319K, Paper
Cezara Zagrean-Tuza, Augustin C Moţ, Tomasz Chmiel, Attila Bende, Ioan Turcu
Quercetin, one of the most abundant flavonoids in plant-based foods, commonly occurs in nature in various glycosylated forms. There is still a less explored aspect regarding the cause of its...
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Lactobacillus fermentum CECT5716 prevents renal damage in NZBWF1 mice model of systemic lupus erythematosus

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00578A, Paper
Néstor de la Visitación, Iñaki Robles-Vera, Marta Toral, Francisco O’Valle, Javier Moleon, Manuel Gómez-Guzmán, Miguel Romero, Marcos Duarte, Manuel Sanchez, Rosario Jimenez, Juan Duarte
The aim of this work was to evaluate whether the immune-modulatory bacteria Lactobacillus fermentum CECT5716 (LC40) protects kidneys in a female mouse model of lupus with hypertension. Twenty-week-old NZBWF1 (lupus)...
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Kinetic profile and urinary excretion of phenyl-γ-valerolactones upon consumption of cranberry: a dose-response relationship

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00806K, Paper
Claudia Favari, Pedro Mena, Claudio Curti, Geoffrey Istas, Christian Heiss , Daniele Del Rio, Ana Rodriguez-Mateos
Cranberries are a rich source of poly(phenols), mainly monomeric and oligomeric flavan-3-ols. However, information on the appearance of their main circulating microbial metabolites, namely phenyl-γ-valerolactones and phenylvaleric acid, is lacking...
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Unveiling the bioactivity potential of Allium triquetrum L. lipophilic fraction: chemical characterization and in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00769B, Paper
Samia Rabah, Kahina Kouachi, Patricia Ramos, Ana T. P. C. Gomes, Adelaide Almeida, Hayate Haddadi-Guemghar, Khodir Madani, Armando Silvestre, Sónia A. O. Santos
The lipophilic composition of Allium triquetrum L. bulbs, flowers and leaves was studied for the first time, by GC-MS. Sixty-two compounds were firstly identified in A. triquetrum L. Fatty acids...
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Mechanisms for Lactobacillus rhamnosus treatment of intestinal infection by drug-resistant Escherichia coli

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00128G, Paper
Na Li, Bing Pang, Junjun Li, Guanwen Liu, Xiaoguang Xu, Dongyan Shao, Chunmei Jiang, Baowei Yang, Junling Shi
Reducing the viability of pathogens may also play an important role for the therapeutic effects of Lactobacillus rhamnosus SHA113 against multiple-drug-resistant E. coli, as well as influencing on the intestinal integrity and functions of animals.
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