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Something Extra | Tuesday

The face of entertainment is changing, and the creative industry is finding new and innovative ways to reach audiences and showcase their talent, and Sunday Live is one such innovation that is creating waves online. The brainchild of entrepreneur...




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Something Extra | Wednesday

Since this week would have been carnival week in Jamaica, we are taking you back to the mecca, Trinidad and Tobago, where just a few months ago, before the pandemic, the region’s local designers, musicians and the revellers were on show. The...




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Something Extra | Thursday

In a time like this, families are being offered time to bond. We eat, laugh, cry and even share a frame together to be added to our reservoir of memories. Here’s a family of familiar faces who did a photo shoot in true Easter-loving style.




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Something Extra | Friday

While many in the heat of this COVID-19 pandemic are staying inside, Jodian Duhaney, her fiancé and a team of friends are out in the communities of St James giving care packages to those in need. For Flashback Friday, Something Extra brings you...




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Something Extra | Tuesday

As the Jamaica and the rest of the world continue to feel the impact of COVID-19, corporate companies are stepping up in a big way, providing support and assistance to communities, individuals and other organisations that are directly or indirectly...




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Something Extra | Wednesday

The fourth in the series of the musical showcase Sunday Live, powered by Sagicor, was held on Sunday, April 19 at Pier One on the Waterfront and featured some of Jamaica’s top up-and-coming talents. The series, which is the brainchild of...




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Something Extra | Thursday

It’s #ThrowBackThursday, and we are looking back to the days when dressing up meant more than just going from room to room. Extra went down memory lane with these hotties who are just counting down the days to go back out and slay.




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Something Extra | Friday

Jamaican cultural ambassador Latonya Style is known for taking her passion and promoting dancehall across the world. Something Extra celebrates Flashback Friday by bringing you behind the scenes of this globetrotter’s dance workshop and tour in...




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Something Extra | Tuesday

Dominique Roache, a Jamaican medical student living and studying in Belize, has found a new hobby since San Pedro went under complete lockdown – self-portraits. “I’ve been inside for so long, I decided to start taking pictures of myself, using...




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Something Extra | Wednesday

Sunday Live continues to showcase the musical prowess of some of Jamaica’s finest talent, and this past Sunday, April 26, the event featured songstress Shuga and reggae bands Earth Kry and TennShann Invasion. Now, with five episodes under its belt...




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Something Extra | Thursday

Facebook, Instagram and Twitter were virtually set ablaze last Sunday when Koffee, Wayne Marshall, and Naomi Cowan took to the stage for the final instalment of Jamaica’s most viewed online entertainment event — the D’Music-powered ‘Digicel...




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Something Extra | Friday

On Wednesday, the world celebrated International Dance Day. So let’s join in the festivities, bringing to the stage highlights of PAH Deaf Dance Company performance showcase during Kingston Creative’s Art Walk, held earlier this year at Water Lane...




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Something Extra | Tuesday

Before COVID-19, media personality Sapphire was bringing the heat with her birthday celebration ‘Fuego’. It’s throwback Tuesday, so let’s rewind with a ‘fêting’ dose of Something Extra.




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Something Extra | Wednesday

The Sunday Live stage continues to showcase some of Jamaica’s talented musicians, and on Sunday, May 3, up-and-coming singer Yeza; and singer, drummer and percussionist Roots Percussionist took centre stage and delivered powerful performances to...




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Something Extra | Thursday

Our favourite Instagram feed this week is by Antiguan native Jaycie Lewis. From head to toe, @aurajae_ has been serving us looks, melanin and style all in one go, and we are 100 per cent loving it. “To be honest, I haven’t been ‘doing looks’. I’ve...




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Something Extra | Friday

Rate those who rate you. Yung Rolaz had this mantra in the streets, providing patrons with the ultimate party experience. Since outside is no longer a festive option, let’s celebrate flashback Friday with hot highlights from the local and...




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An extremely fascinating website along with terrific posts!

This is one of the very most fascinating web sites I have ever before observed. This is quite exciting because of its distinct subject matter as well as remarkable write-ups.




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Hysterectomy and your sex life

A hysterectomy is a surgical procedure that’s done to cure serious problems of the uterus (womb), cervix or even the ovaries. Some women fear that having this procedure done will affect their sex life. Will it truly? Let’s find out. “There are...




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O's aim to rely on experience during rebuild

In outlining their plans to rebuild the Orioles following the least successful season in franchise history, new club officials routinely point to experience: They just did the same thing elsewhere.




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O's ink veteran Escobar, extend spring invite

The Orioles' cloudy infield picture gained some clarity Saturday when the team signed veteran shortstop Alcides Escobar to a Minor League contract with an invitation to Spring Training.




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Impaired Metabolic Flexibility to High-Fat Overfeeding Predicts Future Weight Gain in Healthy Adults

The ability to switch fuels for oxidation in response to changes in macronutrient composition of diet (metabolic flexibility) may be informative of individuals’ susceptibility to weight gain. Seventy-nine healthy, weight-stable participants underwent 24-h assessments of energy expenditure and respiratory quotient (RQ) in a whole-room calorimeter during energy balance (EBL) (50% carbohydrate, 30% fat) and then during 24-h fasting and three 200% overfeeding diets in a crossover design. Metabolic flexibility was defined as the change in 24-h RQ from EBL during fasting and standard overfeeding (STOF) (50% carbohydrate, 30% fat), high-fat overfeeding (HFOF) (60% fat, 20% carbohydrate), and high-carbohydrate overfeeding (HCOF) (75% carbohydrate, 5% fat) diets. Free-living weight change was assessed after 6 and 12 months. Compared with EBL, RQ decreased on average by 9% during fasting and by 4% during HFOF but increased by 4% during STOF and by 8% during HCOF. A smaller decrease in RQ, reflecting a smaller increase in lipid oxidation rate, during HFOF but not during the other diets predicted greater weight gain at both 6 and 12 months. An impaired metabolic flexibility to acute HFOF can identify individuals prone to weight gain, indicating that an individual’s capacity to oxidize dietary fat is a metabolic determinant of weight change.




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Concacaf ‘Hex’ may be adjusted

OTTAWA, Canada (CMC): The Confederation of North, Central American and Caribbean Association Football’s (Concacaf) hexagonal round of qualifying for the 2022 FIFA World Cup in Qatar may have to be scrapped because of the disruption the COVID-19...




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Hexed - JFF finds possible World Cup ­Qualifying structure changes ­‘disadvantageous’

Jamaica Football Federation (JFF) general secretary Dalton Wint says that any potential changes to the Concacaf hexagonal round for the FIFA World Cup qualifiers could present challenges to the nation’s aim of qualifying for Qatar 2022. Wint’s...




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Is the Hep C screening expansion justified?

Until recently, hepatitis C screening was offered to people at increased risk of infection - such as intravenous drug users - but now, the US Centers for Disease Control and Prevention has recommended screening all people born between 1945 and 1965. Kenny Lin, associate professor of family medicine at Georgetown University in Washington, DC, and...




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WHO needs exercise?

Philipe de Souto Barreto argues that, to reduce premature mortality, policies should focus on getting fully inactive people to do a little physical activity rather than strive for the entire population to meet current physical activity recommendations. Read the full analysis paper: http://www.bmj.com/content/350/bmj.h23




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Open Doors For Sex Workers

Following on from the clinical review "Caring for sex workers", we spoke to the team at Open Doors, a sex worker outreach clinic in east London, run from the Homerton University Hospital NHS Foundation Trust. Kim Leveret and Anca Doczi join us to give practical advice on reaching out to sex workers, what barriers exist to them accessing care, and...




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Unexpected findings, with uncertain implications, in research imaging

When healthy volunteers are scanned as part of a research project, unexpected findings, with uncertain implications, can be thrown up. Joanna Wardlaw, professor of applied neuroimaging and honorary consultant neuroradiologist at the University of Edinburgh, joins us to discuss how her group deals with these incidental findings, and what...




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Exercise induced bronchoconstriction

James Smoliga, from High Point University, North Carolina, and Ken Rundell, from The Commonwealth Medical College, Pennsylvania, join us to discuss how to test for, and manage, exercise induced bronchoconstriction, and particularly how to distinguish it from other respiratory conditions. Read the full review at...




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The Weekend Effect - what's (un)knowable, and what next?

We do we know about the weekend effect? As Martin McKee puts it in an editorial on thebmj.com, "almost nothing is clear in this tangled tale" In this roundtable, Navjoyt Ladher, Analysis editor for The BMJ is joined by some of the key academics who have published research and commented on the weekend effect to make sense of what we know and...




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Helping patients with medically unexplained symptoms

Persistent physical symptoms are common and include those symptoms that last at least three months and are insufficiently explained by a medical condition after adequate examination and investigation. Observational studies in primary care report that women, especially those aged 35-45 years, more commonly present with these symptoms. In this...




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American healthcare - what next?

For seven years, Republicans have vowed to repeal the Affordable Healthcare Act (Obamacare), and that promise took a central place in President Trump's campaign. The first major vote to replace it was due to happen last week, but was cancelled at the 11th hour. In advance of the potential vote, The BMJ published a debate asking "Should US doctors...




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“I had two herniated discs in my back, and I was still running” - addicted to exercise

It’s been called “the universal panacea” - exercise has a positive effect on almost all health measures, and governments are actively campaigning for us to do more. But at the opposite end of the scale, the realisation that some people may be addicted to exercise is gaining traction. In this podcast we're joined by Heather Hausenblas - professor...




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Helping patients with complex grief

Each individual’s grief process is unique, when confronted with the death of a loved one, most people experience transient rather than persistent distress - however 10% of bereaved individuals, with an increased risk following the death of a partner or child and loss to unnatural or violent circumstances, experience prolonged grief disorder. In...




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What's going on with life expectancy?

The increase in life expectancy in England has almost “ground to a halt” since 2010 and austerity measures are likely to be a significant contributor. In this podcast Michael Marmot, director at University College London’s Institute of Health Equity, joins us to discuss what might be causing that drop off, and why a decrease in early life chances...




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Exercise in old age - "we need kendo classes in Huddersfield"

There's a crisis in old age care - not just in the UK, around the world, as population demographics shift, and the proportion of older people increase - there's a worry about who's going to look after them, and how much is it going to cost? However, a new analysis on bmj.com says this picture need not be so gloomy - they say that encouraging...




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I thought I wasn't thin enough to be anorexic

Assessing young people with possible eating disorders can be complex for a variety of reasons. Building a therapeutic relationship with a young person with a possible eating disorder and their family is key to enabling a thorough assessment and ongoing management, but it introduces difficult issues regarding confidentiality and risk. In this...




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Doctors and extinction rebellion

Starting in the middle of April, the group “Extinction Rebellion” have organised a series of non-violent direct action protests. Most notably bringing central London to a standstill - but these events are now continuing around the country. Predictably, they have received a lot of criticism - they have also received a lot of support - amongst...




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The sex lives of married Brits

The National Surveys of Sexual Attitudes and Lifestyles is a deep look into the sex lives of us brits - and has been running now for 30 years, giving us some longitudinal data about the way in which those sex lives have changed. The latest paper to be published, based on that data, looks at the frequency of sex - how often different groups are...




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Talk Evidence - Tramadol, medical harm, and alexa

Welcome back to Talk Evidence - where Helen Macdonald and Carl Heneghan take you through what's happening in the world of Evidence. This month we'll be discussing tramadol being prescripted postoperatively, and a new EBM verdict says that should change(1.36). How much preventable harm does healthcare causes (11.20. A canadian project to help...




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The government is lacking detail over Brexit planning

Brexit. Who knows what’s going to happen in the next few weeks, months, years - the uncertainty is high. In the face of that, you’d hope that the government was doing all it could to plan for any eventuality - let alone for a massive, country altering one like suddenly crashing out without a deal - but Martin McKee, professor of public health at...




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Extending the UK's sugar tax to snacks

In the UK, for just over a year, we've been paying the "Soft Drinks Industry Levy" - a tax on sugary beverages intended to reduce our consumption of free sugars. That was based on taxes that had happened in other countries, however, in the UK high sugar snacks, such as confectionery, cakes, and biscuits make a greater contribution to intakes of...




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Brexit - Planning for medicine shortages

This week we saw the release of the much awaited Yellowhammer documents from the government, documents which outline some of the risks involved with Britain’s sudden departure from the EU. The documents themselves outline that there are risks to the supply of medicines - but do not set out the detail of how those risks have been mitigated, and...




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Talking up your research - Sex makes a difference

As editors, we feel like we’re spending a lot of time taking the superlatives out from articles - amazing, novel, important… But new research on BMJ.com suggests that we might not be doing that great a job, and that for some reason, papers authored by men tend to have more of them - because men put more in, or maybe a bias against woman writing in...




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Fuel selection in human skeletal muscle in insulin resistance: a reexamination

DE Kelley
May 1, 2000; 49:677-683
Articles




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High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

Masayuki Saito
Jul 1, 2009; 58:1526-1531
Metabolism




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Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

Markus Tiedge
Nov 1, 1997; 46:1733-1742
Original Article




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Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships

D Dabelea
Dec 1, 2000; 49:2208-2211
Articles




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Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

G Xu
Dec 1, 1999; 48:2270-2276
Articles




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The Relationship of Glycemic Exposure (HbA1c) to the Risk of Development and Progression of Retinopathy in the Diabetes Control and Complications Trial

The Diabetes Control and Complications Trial Research Group
Aug 1, 1995; 44:968-983
Original Article




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PPAR{gamma} Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

Norikazu Maeda
Sep 1, 2001; 50:2094-2099
Pathophysiology