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Time-resolved in situ monitoring of photocatalytic reactions by probe electrospray ionization mass spectrometry

Analyst, 2020, 145,3313-3319
DOI: 10.1039/D0AN00305K, Paper
Zhongbao Han, Xiaoyu Gu, Shirong Wang, Liyan Liu, Ying Wang, Zhen Zhao, Zhan Yu
We report the application of PESI-MS to in situ monitoring of photocatalytic reactions of cationic dyes in suspensions in real-time.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Novel ratiometric electrochemical sensor for no-wash detection of fluorene-9-bisphenol based on combining CoN nanoarrays with molecularly imprinted polymers

Analyst, 2020, 145,3320-3328
DOI: 10.1039/D0AN00345J, Paper
Zhaoyi Liu, Yong Zhang, Bing Li, Xiang Ren, Hongmin Ma, Qin Wei
A ratiometric molecularly imprinted polymers electrochemical sensor was fabricated based on the direct electrochemical oxidation of BHPF on CoN nanoarray electrode.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Using the interfacial barrier effects of p–n junction on electrochemistry for detection of phosphate

Analyst, 2020, 145,3217-3221
DOI: 10.1039/C9AN02579K, Communication
Yu Ding, Minggang Zhao, Jiatuo Yu, Xiaomin Zhang, Zhengming Li, Hui Li
The electrochemical response to phosphate was produced by the induced change of the interfacial barrier of the NiO/ZnO p–n junction foam.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rapid detection of 21 β-lactams using an immunochromatographic assay based on the mutant BlaR-CTD protein from Bacillus Licheniformis

Analyst, 2020, 145,3257-3265
DOI: 10.1039/D0AN00421A, Paper
Yue Li, Xinxin Xu, Liqiang Liu, Hua Kuang, Liguang Xu, Chuanlai Xu
In this study, a gold immunochromatographic assay (GICA) based on a penicillin receptor protein (PBP) is proposed to simultaneously detect penicillin, cephalosporin, and carbapenem antibiotics in milk and chicken.
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Synthesis of a manganese dioxide nanorod-anchored graphene oxide composite for highly sensitive electrochemical sensing of dopamine

Analyst, 2020, 145,3283-3288
DOI: 10.1039/D0AN00348D, Paper
Juan Li, Huifang Shen, Suhua Yu, Geshan Zhang, Chuanli Ren, Xiaoya Hu, Zhanjun Yang
A novel manganese dioxide nanorod-anchored graphene oxide (MnO2 NRs/GO) composite was synthesized by a simple hydrothermal method for the development of a highly sensitive electrochemical sensor for dopamine.
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Development of a chromophore-solid phase peptide reaction assay (C-SPRA) for assessing skin sensitization in vitro

Analyst, 2020, 145,3211-3216
DOI: 10.1039/C9AN02514F, Communication
Hiroshi Miyazaki, Yoshio Hamada, Hikaru Takaishi, Yuuki Minamino, Hidefumi Ikeda, Hideaki Mekata, Masayuki Takaishi, Kunihiko Yamashita, Kenji Usui
We developed an in vitro chromophore-solid phase peptide reaction assay (C-SPRA) using chromophores and immobilized peptides on microbeads. C-SPRA would enable accurate and high-throughput assessments of various chemicals.
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FRET based fluorescent ratiometric probes for rapid detection of endogenous hydrogen sulphide in living cells

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00531B, Paper
Yuming Zhang, Yuncong Chen, Bai Yang, Xueling Xue, Weijiang He, Zijian Guo
Real time monitor of hydrogen sulphide (H2S) level change is of crucial importance for the study of its complicated roles in physiology. Herein, we developed a FRET strategy for designing...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Laser-induced graphene hybrid photoelectrode for enhanced photoelectrochemical detection of glucose

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00252F, Paper
Hui Li, Chengxiang Guo, Changchun Liu, Lei Ge, Feng Li
The in situ and synchronous fabrication of Ni0/NiO–CdS–graphene hybrid photoelectrodes is developed using a facile and scalable direct-laser-writing method for photoelectrochemical detection of glucose.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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In situ amplified photothermal immunoassay for neuron-specific enolase with enhanced sensitivity using Prussian blue nanoparticle-loaded liposomes

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00417K, Paper
Li-Juan Zhi, Ai-Li Sun, Dianping Tang
Methods based on prussian blue nanoparticles (PBNPs) have been reported for photothermal immunoassays in analytical nanoscience fields but most suffer from low sensitivity and are not beneficial for routine use.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Naked-Eye Sensing of Phytic Acid at Sub-Nanomolar Level in 100% Water Medium by Charge Transfer Complex Derived from off-the-shelf Ingredients

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00671H, Paper
Nilanjan Dey
Naked-eye sensing of phytic acid, one of the most abundant antinutrients, was achieved in 100% water medium using charge transfer complex, comprised of pyranine and methyl viologen. Since both the...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A homogeneous photoelectrochemical hydrogen sulfide sensor based on the electronic transfer mediated by tetrasulfophthalocyanine

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00302F, Paper
Xinyang Wang, Huanan Zhao, Zhonghui Chen, Fang Luo, Longhua Guo, Bin Qiu, Zhenyu Lin, Jian Wang
A homogeneous photoelectrochemical sensor for H2S detection based on the electronic transfer mediated by [Fe(III)PcS4]+ was developed with an un-modified photoelectrode.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Biocompatible Alkyne arms containing Schiff base Fluorescence Indicator for Duel detection of CdII and PbII at Physiological pH and its Application to Live Cell Imaging

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00862A, Paper
Jebastin Andrews S.G, Benita Jeba Silviya S, Jeyanthi Dharmaraj, Winfred Jebaraj J, Sathya Devi E, C. Balakrishnan
An alkyne arms containing salen-type Schiff base ligand, 6,6'-((1E,1'E)-(1,2-phenylenebis(azanylylidene))bis(ethan-1-yl-1-ylidene))bis(3-(prop-2-yn-1-yloxy)phenol) (H2L), is reported here as a dual chemosensor for CdII and PbII ions. The ligand, H2L was characterized by various spectral...
The content of this RSS Feed (c) The Royal Society of Chemistry




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An Integrated Microfluidic Platform for Selective and Real-Time Detection of Thrombin Biomarkers using a Graphene FET

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00251H, Paper
Niazul Islam Khan, Mohammad Mousazadehkasin, Sujoy Ghosh, John G. Tsavalas, Edward Song
Lab-on-a-chip technology offers an ideal platform for low-cost, reliable, and easy-to-use diagnostics of key biomarkers needed for early screening of diseases and other health concerns. In this work, a graphene...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Core–shell magnetic microporous covalent organic framework with functionalized Ti(IV) for selective enrichment of phosphopeptides

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00038H, Paper
Fengjuan Ding, Yameng Zhao, Haiyan Liu, Weibing Zhang
We fabricated a core-shell magnetic Ti4+-functionalized covalent organic framework composite to selectively capture phosphopeptides in biosamples. This method is applicable to achieve rapid, selective and efficient phosphopeptide analysis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Phenyl doped graphitic carbon nitride nanosheets for sensing of copper ions in living cells

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00795A, Paper
Zhiping Song, Yuanteng Xu, Liangqia Guo
Copper (Cu) is a vital mental element for human and animals. Monitoring and evaluating the concentration level of Cu2+ in biological body is an effective way to prevent a variety...
The content of this RSS Feed (c) The Royal Society of Chemistry




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[ASAP] A Synthetic Malonyl-CoA Metabolic Oscillator in <italic toggle="yes">Komagataella phaffii</italic>

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00378




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[ASAP] Introduction of the Menaquinone Biosynthetic Pathway into <italic toggle="yes">Rhodobacter sphaeroides</italic> and <italic toggle="yes">de Novo</italic> Synthesis of Menaquinone for Incorporation into He

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00066




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[ASAP] Bacteriophage Inspired Growth-Decoupled Recombinant Protein Production in <italic toggle="yes">Escherichia coli</italic>

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00028





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[ASAP] Pyridine-Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00280




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[ASAP] Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00117




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[ASAP] Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00035




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[ASAP] Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01835




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[ASAP] Correction to Toggling Preassembly with Single-Site Mutation Switches the Cytotoxic Mechanism of Cationic Amphipathic Peptides

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00608




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[ASAP] Discovery and Structure–Activity Relationship Study of (<italic toggle="yes">Z</italic>)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00227




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[ASAP] Correction to Photoactivatable Prolyl Hydroxylase 2 Inhibitors for Stabilizing the Hypoxia-Inducible Factor with Light

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00599




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[ASAP] Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01336




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[ASAP] Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00015




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[ASAP] p62/SQSTM1, a Central but Unexploited Target: Advances in Its Physiological/Pathogenic Functions and Small Molecular Modulators

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02038




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[ASAP] Both <sc>d</sc>- and <sc>l</sc>-Glucose Polyphosphates Mimic <sc>d</sc>-<italic toggle="yes">myo</italic>-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00215




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[ASAP] Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00337




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[ASAP] Discovery of <italic toggle="yes">N</italic>-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1<italic toggle="yes">H</italic>-pyrrolo[2,3-<italic toggle=&q

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00628




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[ASAP] Cancer Immunotherapy through the Inhibition of Diacylglycerol Kinases Alpha and Zeta

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00118




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[ASAP] Glycans Meet Sphingolipids: Structure-Based Design of Glycan Containing Analogues of a Sphingosine Kinase Inhibitor

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00665




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[ASAP] Peptoid NPhe<sup>4</sup> in AGRP-Based c[Pro<sup>1</sup>-Arg<sup>2</sup>-Phe<sup>3</sup>-Phe<sup>4</sup>-Xxx<sup>5</sup>-Ala<sup>6</sup>-Phe<sup>7</sup>

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00641




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[ASAP] Novel HIV-1 Protease Inhibitors with Morpholine as the P2 Ligand to Enhance Activity against DRV-Resistant Variants

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00043




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[ASAP] Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00045




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[ASAP] Substituted Naphthalenediimide Compounds Bind Selectively to Two Human Quadruplex Structures with Parallel Topology

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00041




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[ASAP] Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00076




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[ASAP] Assembling Pharma Resources to Tackle Diseases of Underserved Populations

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00051




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[ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00639




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[ASAP] Development of Selective Steroid Inhibitors for the Glucose-6-phosphate Dehydrogenase from <italic toggle="yes">Trypanosoma cruzi</italic>

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00106




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[ASAP] Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00009




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[ASAP] Synthesis and Evaluation of <sup>11</sup>C- and <sup>18</sup>F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00127




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Filtering (photo) filters

A lot of photo apps allow you to add filters before sharing. The typical UI for picking a filter is a row of little thumbnails that can be horizontally scrolled. I’m sure you’ve used it many times. It looks something like this:

The problem

A filter picker like that is easy to understand and works pretty well. But in my case, there is something that has been bugging me a bit. Here is how I use it:

  1. I start with the first thumbnail and then just keep tapping one after the other.
  2. If there is a filter that I like, I try to remember its name. And somewhat its position, but more like “somewhere at the beginning”.
  3. Then once I reach the end, I start scrolling back trying to find the ones I liked.
  4. Usually there are like 2-3 filters that I would like to quickly compare before making my final choice. But it’s quite hard to scroll between them, especially if they are far apart. Also having to remember their name/position costs some precious brain power.

Now, I don’t really know how most people use these filter pickers. Could be that:

  1. Most people just stop once they found a filter they kinda like and don’t bother trying the rest.
  2. Or some have a few favorites and know their name/position already.
  3. You could also just look at the little thumbnails. But some filters are very similar and I need to see them on the actual photo to judge.

Possible solutions

So I was thinking about some possible improvements:

1. Order by popularity

Automatically order the filters based on how often they get used. This makes filters that you use most appear at the beginning and are easier to get to. You could always keep scrolling in case you’re in the mood for something new. This would of course mess it up for people that have filters remembered by position. But not sure how many actually do that.

2. Manual re-order

Let people manually reorder the position. Could be done similar like the home screen icons on iOS (long press until they wiggle, then drag around). I would probably move my favorites to the front and also sort based on color/style.

3. Narrow down

Let people temporarily toss away the filters they don’t want. This would allow you to narrow down your selection to just a few for easier comparison. Of course, all the filters would be back next time you take a new photo.

Or probably even better (3B): Instead of throwing away the ones you don’t like (could be tedious if there are a lot of filters), you could push up only the ones you like and they would move to the right with a visual separator. It’s similar how you can pin a Chrome browser tab to separate it from the rest. Then once you scrolled to the end, you would have all your previously selected filters next to each other, waiting to be the lucky winner.

Conclusion

I understand that the suggestions might make a photo app more complicated and harder to explain to a new user. But it could be more a “power user” feature that you’re not forced to use if you don’t want to. Anyways, in case I’m not the only one with this (small) problem, I hope some day we will have a better way to filter filters. Ohh.. and let me know if you’re already using an app that tackles this somehow.

Update

Thanks for all the comments. Good to see more people thinking about this. I played around a bit more with the demo, mostly after the conversation with Ignacio in the comments below. So here a 4th option:

4. Select and cycle

Let people select a couple filters and then cycle through them by tapping on the photo. It’s actually similar to 3B, but it keeps the UI simple by using the photo as the secondary navigation control. Here the steps how to use:

  1. You can tab each filter until you find one you like.
  2. If you tab a 2nd time on that filter, it gets selected as a “favorite”. It will move up a little to visualize it.
  3. You can keep trying other filters and mark more as favorites.
  4. Once you reached the end (or think you have enough), you can tap on the photo above the filter picker to quickly cycle through all your previously selected (favorited) filters. Now comparing different filters is really quick and easy.

Try the demo.

The implementation of the demo could still be improved. It is a bit hard to discover that you can tap the photo to cycle through your favorites. Might need some visual clue to help understand it better. Adding swipe gestures instead of tapping would also improve UX. Or to remove a filter from your favorite selection, you could just swipe down on the image. Also note that the filters are CSS based and still a bit glitchy when animating. But you should get the idea.

Update II

Manuel Haring explored a similar concept where you can push up filters to narrow down your selection.

Here a larger video that has even a third selection stage.




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The matter of photography in the Americas / Natalia Brizuela and Jodi Roberts ; with contributions by Lisa Blackmore, Amy Sara Carroll, Marianela D'Aprile, María Fernanda Domínguez, Heloisa Espada, Rachel Price, Diana Ruiz, Tatiane Santa Ro

Rotch Library - TR184.B75 2018




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Legacy of the masters: painting and calligraphy of the Islamic world from the Shavleyan family collection / Will Kwiatkowski ; with contributions by John Seyller

Rotch Library - N6260.K87 2019




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For your pleasure: Johannes Brus, photoworks and sculptures / with an essay by Clément Chéroux

Rotch Library - N6888.B745 A4 2018




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The Pre-Raphaelites and science / John Holmes

Hayden Library - NX454.5.P7 H65 2018




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Gordon Parks: the new tide, early work, 1940-1950 / Philip Brookman ; with essays by Maurice Berger, Sarah Lewis, Richard J. Powell, Deborah Willis ; series editor, Peter W. Kunhardt, Jr

Rotch Library - TR647.P37 2018