Lakers star Anthony Davis was held to five points in the first half because of foul trouble but scored 25 points and had eight rebounds after halftime.

Trade groups expect the British government to roll out new coronavirus travel restrictions on Sunday, including a quarantine for out-of-country arrivals. And they're already pushing back publicly.

Convicted televangelist Jim Bakker is recovering from a stroke, says his wife, Lori.

Wildfires brought evacuations in the Florida panhandle.

UCLA completed the nonconference portion of its 2026 football schedule, agreeing to a game with Nevada at the Rose Bowl on Sept. 19, 2026.

As of 5 p.m. Wednesday, hundreds of students were forced to leave Stanford University, which is also reducing financial aid for students.

UCLA will cancel traditional graduation ceremonies and hold them remotely to prevent the spread of the coronavirus, Chancellor Gene Block announced Wednesday.

Donate the cost of a canceled ticket, take an online dance class, buy a piece of fine art: Here are 22 ways to help artists weather the coronavirus storm.

Artist Relief, which has given grants to 200 artists in need, reports that nearly 52,000 people have applied. A survey shows two out of three people are unemployed.

Marie Mutsuki Mockett's 'American Harvest' looks at the divide between the heartland and those who seldom think about where our food comes from.

How Robert Kolker came to write "Hidden Valley Road," about the Galvin family and the disease that tore through them, with such empathy.

The Postal Service is as important to the United States as its language and its highways. Losing it would forever change the country for the worse.

Actress-producer Eva Longoria has sold her Hollywood Hills compound, which was previously owned by actor Tom Cruise, for $8.25 million.

The fight over emissions between California and the White House could last years.

On Saturday, Global Citizen will present the all-star concert "One World: Together at Home," to air on CBS, NBC and ABC. It has already raised $40 million for the WHO.

Shoppers didn't know it at the time, but their final spree at Amoeba Music's Hollywood store on Sunset Boulevard was their last, as the original location will not reopen.

Playing weddings was a safe, steady gig for musicians. Until coronavirus. Now wedding bands, DJs and planners wonder when their next gig might come.

Arsenal have released a statement after Olympiakos and Nottingham Forest owner Evangelos Marinakis tested positive for coronavirus - less than two weeks after the Greek Super League outfit dumped the Gunners out of the Europa League at the Emirates Stadium.

Nottingham Forest owner Evangelos Marinakis has announced he has coronavirus - he attended the home game against Millwall on Friday.

Evangelos Marinakis is recovering from coronavirus two weeks after announcing his diagnosis.

Rangers beat Aberdeen 5-0 in the Scottish Premiership to go within a point of Celtic at the top of the table, and former Rangers star Alan Hutton has hailed striker Jermain Defoe as “unbelievable” after Steven Gerrard’s sixth win of the season.

DAME VERA LYNN played an instrumental role in keeping up wartime morale and is highly respected today - but unearthed accounts reveal why she will still be relevant even in the next millennium.

Evander Holyfield has confirmed he is coming out of retirement.

KEIR STARMER's secret weapon against Prime Minister Boris Johnson has been revealed by Professor Tim Bale who detailed what the Labour leader can succeed in.

An Indianapolis photographer met a New Jersey painter on Instagram because they liked each other's work. Now they're married and run an art business.

The documentary "Eva" about Holocaust survivor Eva Kor premieres April 5.

Jerry Sneva dies at age 69

Recuperação pode ser um processo lento, dependendo da gravidade do quadro.

Os ‘lazarettos’ de Dubrovnik são a memória da luta da cidade no combate a doenças infecciosas séculos atrás.

Desde 2017, a intenção do poder público vinha sendo acelerar destruições, que evitam que armas caiam nas mãos do crime; órgãos públicos não sabem explicar a razão da queda.

Profissionais de enfermagem relatam falta de equipamentos de proteção, baixas nas equipes e lotação; em ofício, governador Witzel reconhece que esforços contra a covid-19 não foram suficientes e que estuda endurecer confinamento.

Evan Davis is now writing a new blog, as part of his new role at the Today programme. You can find it at http://www.bbc.co.uk/evandavis.

Indiana on Monday joined a handful of states, including several of its neighbors, by shutting down nonessential travel and businesses.

The Sheriff Civilian Oversight Commission voted Thursday to subpoena L.A. County Sheriff Alex Villanueva for testimony regarding the coronavirus outbreak in the jails.

Evansville native and pro golfer Dylan Meyer discusses what his plans would have been this spring, his dream golf foursome and more.

The Force was reportedly not with the original scripts of the anticipated show.

Contrarian bettors are off to their best start through the first four weeks of the season since 2003.

A mostly millennial crowd explored the upgraded and interactive museum.

Rather than focus on technical decisions alone, architects and senior technologists need to combine organizational and technical knowledge to effect change in their company’s structure and processes. To accomplish that, they need to connect the IT engine room to the penthouse, where the business strategy is defined. In this guide, author Gregor Hohpe shares real-world advice and hard-learned lessons from actual IT transformations. His anecdotes help architects, senior developers, and other IT professionals prepare for a more complex but rewarding role in the enterprise.

Tesla CEO Elon Musk said Saturday the company will file a lawsuit against Alameda County and threatened to move its headquarters and future programs to Texas or Nevada immediately, escalating a fight between the company and health officials over whether its factory in Fremont can reopen. Tesla had planned to bring back about 30% of […]

Las Vegas, Nevada

The Amateur Traveler talks to Doug McConnell of OpenRoad.tv about his love for the Eastern Sierra Nevada mountains. Doug has been going to this rugged, stark and beautiful area of California and Nevada since he was a kid. He tells us about Hollywood's love of this area, the oldest trees on the planet, the water wars of California, the tufa fields of Mono Lake, the ghost town of Bodie and more. He also tells of his friends Galen and Barbara Rowell who called this area their home until their deaths in 2002. Galen was a renowned nature photographer and Barbara was his partner and pilot.

The Amateur Traveler travels to Geneva and experiences the Escalade which celebrates the defeat of the Savoy in 1602. Geneva is the home to many UN agencies, an old town, a cathedral and an excellent rare book collection. You can also find lots of ways to eat melted cheese and other Swiss treats on the shore of beautiful Lake Geneva. In this unusual episode Chris overcomes a technical microphone difficulty to record an episode on the road. This episode inlcudes some of the sounds of the Escalade festival.

The Amateur Traveler talks to Bethany of the Nevada Tourism Bureau about Lake Tahoe. Lake Tahoe is a high elevation alpine lake on the border of California and Nevada. It is surrounded by 18 ski areas so it is a popular winter destination. In the winter it is also a great place for back country hiking, cross country skiing, snowshoeing, and snowmobiling. In the Summer, Tahoe is a popular area for hiking, fishing and outdoor activities. But, there is another side to Tahoe which is the casinos, restaurants, and entertainment of Nevada's South Tahoe.

The Amateur Traveler talks to Hunter Hillegas author of the Vegas Mate iPhone app about Las Vegas. The Amateur Traveler has covered Las Vegas before but the city is constantly changing.

Hear about travel to Geneva, Switzerland as the Amateur Traveler talks to Leyla Giray Alianak about the region where she lives. 

The Shelburne Retirement Residence has been devastated by an outbreak of COVID-19, with 90 per cent of its residents becoming infected.

29 August 2019

Telomeres are specific nucleoprotein structures that are located at the ends of linear eukaryotic chromosomes and play crucial roles in genomic stability. Telomere DNA consists of simple repeats of a short G-rich sequence: TTAGGG in mammals and TTTAGGG in most plants. In recent years, the mammalian telomeric G-rich repeats have been shown to form G-quadruplex (G4) structures, which are crucial for modulating telomere functions. Surprisingly, even though plant telomeres are essential for plant growth, development, and environmental adaptions, only few reports exist on plant telomeric G4 DNA (pTG4). Here, using bulk and single-molecule assays, including CD spectroscopy, and single-molecule FRET approaches, we comprehensively characterized the structure and dynamics of a typical plant telomeric sequence, d[GGG(TTTAGGG)3]. We found that this sequence can fold into mixed G4s in potassium, including parallel and antiparallel structures. We also directly detected intermediate dynamic transitions, including G-hairpin, parallel G-triplex, and antiparallel G-triplex structures. Moreover, we observed that pTG4 is unfolded by the AtRecQ2 helicase but not by AtRecQ3. The results of our work shed light on our understanding about the existence, topological structures, stability, intermediates, unwinding, and functions of pTG4.