It was just a few days ago,when stylist Aastha Sharma shared a picture of Lisa Ray from the sets of Four More Shots Please!, where she was seen sporting a stunning white bridal ensemble by Gaurav Gupta. And now, recently,

Being a mother is definitely not an easy job and we should take time to appreciate our mothers every day but particularly on Mother's Day. Today is Mother's Day, a day celebrated to honour mother and respect maternal bonds.

Bollywood actress Shraddha Kapoor has absolutely left us stunned with her sartorial choices, be it in ethnic or western outfit. Even at the promotional rounds of her films, it's always a treat to watch the diva making gorgeous statements in

The Union Health Minister Harsh Vardhan said the testing capacity for COVID-19 has been ramped up to around 95,000 tests per day and a total of over 15 lakh tests have been conducted so far across hundreds of government and private labs.

The state also reported death of 48 patients, taking the death toll to 779, said a health department official.

Behind every successful man, there is a woman. This quote is perfectly apt for all the wonderful mothers across the world. Mother's Day marks an occasion when mothers are thanked for their immense efforts, love, and for compromising their dreams to

Pakistan said on Sunday that it has “fully complied” with the ICJ’s judgement in the Kulbhushan Jadhav case, days after India’s lead counsel asserted

With the addition of 50 new cases, total number of coronavirus (Covid-19) positive cases in Andhra Pradesh has gone up to 1,980.According to governm

Tamil Nadu witnessed another spike in Covid-19 positive cases today with 669 to go past the 7,000-mark at 7,204.Chennai alone had recorded 509 new ca

Output cuts help,but demand recovery still timid

Ticket booking counters at the railway stations shall remain closed and no counter tickets including platform tickets shall be issued.

1. Prince Harry urges Invictus Games family to rally  PerthNow
2. Prince Harry marks Invictus Games in new video message: Watch  NEWS.com.au
3. 'Life has changed dramatically': Harry shares unexpected video from new LA home  9Honey
4. ‘Life has changed dramatically’: Harry’s surprise video from Hollywood home  7NEWS.com.au
5. Prince Harry says 'life has changed dramatically for us all' in new message from LA  Daily Star
6. View Full coverage on Google News

SUDDENLY JELLYFISH.

The theme here is simple: whatever your dog is looking at might be pretty, but your dog is always prettier. Got it?

As I predicted, Kelly showed none of the tenacious questioning of the accuser’s story she so successfully leveraged in the Duke lacrosse case. In that case, she was clearly fed talking points from the defendants. In this one, she was clearly working on behalf of the accuser. And her own ambitions to get back into right-wing media.

Kelly never bothered to ask, much less explore, many of the disturbing contradictions in Reade’s story that have stymied reporters. Instead, we got a melodramatic and, I must say, compelling recitation of Reade's accusation. Throughout, Kelly did her utmost to make Reade sympathetic and credible and only pretended to ask tough questions.

For example, early on, Reade hinted at a spotty work history. Kelly neatly summarized Reade’s resumé for her, with details provided by someone unnamed. On Thursday, high-profile attorney Douglas Wigdor announced that he is representing Reade.

As Arizona's cities are laying off and furloughing workers because of cratering revenues as a result of the coronavirus pandemic, their Republican senator is telling them to toughen up. She isn't going to help them by voting for any financial support for state local government, citing that "blue state bailout" bullshit.

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He's still giving the money back though.

He's still giving the money back though.

He's still giving the money back though.

Vincent Edwards signed with the Houston Rockets on Thursday, per the team.

Bollywood Movies on Zero Dollar Movies

Kingston’s top health officials say that there are no current cases of COVID-19 active in the city.

Members Event

Event participants

Professor Joseph S Nye, University Distinguished Service Professor, Harvard Kennedy School of Government
Chair: Gideon Rachman, Chief Foreign Affairs Commentator, Financial Times

The government said it's distributing the promising coronavirus drug, remdesivir, to some hard-hit states. Eventually, all 50 states should get it.

β-1,3-d-Glucan is a ubiquitous glucose polymer produced by plants, bacteria, and most fungi. It has been used as a diagnostic tool in patients with invasive mycoses via a highly-sensitive reagent consisting of the blood coagulation system of horseshoe crab. However, no method is currently available for measuring β-1,6-glucan, another primary β-glucan structure of fungal polysaccharides. Herein, we describe the development of an economical and highly-sensitive and specific assay for β-1,6-glucan using a modified recombinant endo-β-1,6-glucanase having diminished glucan hydrolase activity. The purified β-1,6-glucanase derivative bound to the β-1,6-glucan pustulan with a KD of 16.4 nm. We validated the specificity of this β-1,6-glucan probe by demonstrating its ability to detect cell wall β-1,6-glucan from both yeast and hyphal forms of the opportunistic fungal pathogen Candida albicans, without any detectable binding to glucan lacking the long β-1,6-glucan branch. We developed a sandwich ELISA-like assay with a low limit of quantification for pustulan (1.5 pg/ml), and we successfully employed this assay in the quantification of extracellular β-1,6-glucan released by >250 patient-derived strains of different Candida species (including Candida auris) in culture supernatant in vitro. We also used this assay to measure β-1,6-glucan in vivo in the serum and in several organs in a mouse model of systemic candidiasis. Our work describes a reliable method for β-1,6-glucan detection, which may prove useful for the diagnosis of invasive fungal infections.

Multidrug resistance (MDR) in cancer arises from cross-resistance to structurally- and functionally-divergent chemotherapeutic drugs. In particular, MDR is characterized by increased expression and activity of ATP-binding cassette (ABC) superfamily transporters. Sphingolipids are substrates of ABC proteins in cell signaling, membrane biosynthesis, and inflammation, for example, and their products can favor cancer progression. Glucosylceramide (GlcCer) is a ubiquitous glycosphingolipid (GSL) generated by glucosylceramide synthase, a key regulatory enzyme encoded by the UDP-glucose ceramide glucosyltransferase (UGCG) gene. Stressed cells increase de novo biosynthesis of ceramides, which return to sub-toxic levels after UGCG mediates incorporation into GlcCer. Given that cancer cells seem to mobilize UGCG and have increased GSL content for ceramide clearance, which ultimately contributes to chemotherapy failure, here we investigated how inhibition of GSL biosynthesis affects the MDR phenotype of chronic myeloid leukemias. We found that MDR is associated with higher UGCG expression and with a complex GSL profile. UGCG inhibition with the ceramide analog d-threo-1-(3,4,-ethylenedioxy)phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol (EtDO-P4) greatly reduced GSL and monosialotetrahexosylganglioside levels, and co-treatment with standard chemotherapeutics sensitized cells to mitochondrial membrane potential loss and apoptosis. ABC subfamily B member 1 (ABCB1) expression was reduced, and ABCC-mediated efflux activity was modulated by competition with nonglycosylated ceramides. Consistently, inhibition of ABCC-mediated transport reduced the efflux of exogenous C6-ceramide. Overall, UGCG inhibition impaired the malignant glycophenotype of MDR leukemias, which typically overcomes drug resistance through distinct mechanisms. This work sheds light on the involvement of GSL in chemotherapy failure, and its findings suggest that targeted GSL modulation could help manage MDR leukemias.

“Badass” new method uses a magnetised protein to activate brain cells rapidly, reversibly, and non-invasively

Researchers in the United States have developed a new method for controlling the brain circuits associated with complex animal behaviours, using genetic engineering to create a magnetised protein that activates specific groups of nerve cells from a distance.

Understanding how the brain generates behaviour is one of the ultimate goals of neuroscience – and one of its most difficult questions. In recent years, researchers have developed a number of methods that enable them to remotely control specified groups of neurons and to probe the workings of neuronal circuits.

Related: Remote control of brain activity with heated nanoparticles

Related: Researchers read and write brain activity with light

Billy Crystal, Tiffany Haddish, Kenan Thompson and Byron Allen are set to co-host Sunday's Feeding America Comedy Festival.

Letter submitted by Marc R. Rosenblum, Deputy Director, U.S. Immigration Program, at the request of the Minority Staff of the House Oversight and Government Reform Committee for the February 25, 2015 joint subcommittee hearing reviewing apprehension, detention, and release policies regarding unauthorized immigrants.

A group that says pandemic-related restrictions are more harmful than COVID-19 itself held a rally at the Manitoba Legislative Building on Saturday.

Canadians working aboard two cruise ships, who have been prevented from coming ashore due to COVID-19 concerns, have finally been allowed to return home.

Filmfare recommends: Bollywood films revolving around journalism  Filmfare

Why does Bollywood use the offensive practice of brownface in movies?  CNN

Personal Agenda with Ricky Kej: “Best thing about lockdown? My dog is really happy!”  Hindustan Times

From watching Ramayan to dancing to Bollywood music, Nurvi's quarantine time looks fun! - entertainment  Mid-Day

1. Happy Mother's Day: Karisma to Sushmita, a look at Bollywood's single mum's who have paved their own way  PINKVILLA
2. Mother’s Day 2020: From Aishwarya Rai to Kareena Kapoor, check out pics of these Bollywood moms and...  Hindustan Times
3. Happy Mother's Day 2020: Kareena Kapoor, Shilpa Shetty lead B-Town stars celebrate motherhood, wish mothers on this precious day | In Pics  Jagran English
4. When Aishwarya Rai Bachchan was asked to pick between Kareena Kapoor Khan & Rani Mukerji; Here’s what she said  PINKVILLA
5. Mother’s Day 2020: Single Mothers of Bollywood  News18
6. View Full coverage on Google News

1. The person who loves us tirelessly and unconditionally: Ravi Shastri, Virat Kohli wish Happy Mother's Day  India Today
2. Maa Jaisa Koi Nahi: Virat Kohli and Virender Sehwag Lead Mother's Day Wishes  News18
3. Mother’s Day: Sports stars thank their moms for unconditional love, sacrifices and prayers  The Indian Express
4. Virat Kohli, Yuvraj Singh Lead Wishes As Sports Fraternity Celebrate Mother's Day 2020  NDTVSports.com
5. Mothers Day: Laxman, Mayank, Rahane lead as cricketers extend wishes to super moms - Republic World  Republic World
6. View Full coverage on Google News

A new OM Italy team member participates in an English Scout Camp, which brings the Gospel to children and gives her new cultural insight.

After taking inventory of the relief effort, OM Philippines workers, in partnership with churches, distribute relief necessities to some of the least-reached disaster sites.

IT could have been a warm welcome home for a conquering comedy hero when Billy Connolly appeared before an audience of Scottish school children at the BBC in Glasgow.