President Marcos has announced that the Philippines will participate in the 4th Global Ministerial Conference on Road Safety to be held in Morocco in February next year.

Extremist violence has been escalating in Pakistan, with minorities of all stripes being targeted. Even Islamic sects are not spared.

1. ‘Ek Hain Toh Safe Hain’: The Effect Of PM Modi's Slogan On Maharashtra’s Muslim Seats  News18
2. ‘Congress’s shahi parivar thinks it is born to rule India': PM Modi in Maharashtra  Hindustan Times
3. "Most Unstable Vehicle": PM Modi's Jibe At Maha Vikas Aghadi In Maharashtra  NDTV
4. Rahul Gandhi's 'Golden Goose' Is Revant Reddy | Claims of Congress Funding Accusation | India Today  India Today
5. Pune to progress faster in next five years, says PM Modi  The Times of India

On the 7th of November 2024, the Gauteng MEC for Finance and Economic Development, Lebogang Maile, delivered a keynote address at Bolt South Africa's Global Safety Campaign launch in Johannesburg. The campaign is aimed at improving safety in the e-hailing industry

The Asian Development Bank (ADB) has provided loans to financial intermediaries to support projects “whose individual financing requirements are not large enough to warrant the direct supervision of ADB.”

The Republic of Armenia is located at the intersection of major tectonic faults, making it highly prone to seismic activity. The devastation of the 1988 Spitak earthquake claimed about 25,000 lives, including 6,000 school children; left 517,000 people homeless, destroyed 190 schools and many urban infrastructures; and incurred direct economic losses of $15 billion-$20 billion. The recent 7.8-magnitude earthquake in neighboring Trkiye and Syria in 2023 is a wake-up call for Armenia, posing a significant threat to the country. rkiye and Syria in 2023 is a wake-up call for Armenia, posing a significant threat to the country.

Dangerous radiation reaches Mars at levels we aren't exposed to on Earth, which makes the Red Planet a particularly dangerous place to be during pregnancy

Title: U.S. to Be Removed From E.U. Safe Travel List
Category: Health News
Created: 8/30/2021 12:00:00 AM
Last Editorial Review: 8/30/2021 12:00:00 AM

Title: Are Baby Bottles Safe?
Category: Health News
Created: 8/27/2007 12:00:00 AM
Last Editorial Review: 8/27/2007 12:00:00 AM

Title: Sunglasses Rival Lotions as Vital for Safety
Category: Health News
Created: 8/20/2010 12:10:00 PM
Last Editorial Review: 8/23/2010 12:00:00 AM

Title: Hepatitis E Vaccine Appears Safe, Effective
Category: Health News
Created: 8/23/2010 10:10:00 AM
Last Editorial Review: 8/24/2010 12:00:00 AM

Title: Herpes Drugs May Be Safe in Early Pregnancy
Category: Health News
Created: 8/25/2010 11:17:00 AM
Last Editorial Review: 8/25/2010 11:17:09 AM

Title: Are The Eggs in Your Fridge Safe to Eat?
Category: Health News
Created: 8/25/2010 12:10:00 PM
Last Editorial Review: 8/26/2010 12:00:00 AM

Title: Eggs Being Produced by Recall Farms Safe, if Pasteurized, Experts Say
Category: Health News
Created: 8/26/2010 12:10:00 PM
Last Editorial Review: 8/27/2010 12:00:00 AM

Title: Report: Vaccines Generally Safe, Cause Few Health Problems
Category: Health News
Created: 8/26/2011 11:01:00 AM
Last Editorial Review: 8/26/2011 12:00:00 AM

Title: Doctors' Tips for Backpack Safety
Category: Health News
Created: 8/25/2013 9:35:00 AM
Last Editorial Review: 8/26/2013 12:00:00 AM

Title: Expert Tips for School Bus Safety
Category: Health News
Created: 8/24/2013 9:35:00 AM
Last Editorial Review: 8/26/2013 12:00:00 AM

Title: Health Tip: Pack Safe School Lunches
Category: Health News
Created: 8/27/2013 7:35:00 AM
Last Editorial Review: 8/27/2013 12:00:00 AM

Title: Deep Brain Stimulation Safe for Older Parkinson's Patients: Study
Category: Health News
Created: 8/26/2014 12:35:00 PM
Last Editorial Review: 8/27/2014 12:00:00 AM

Title: Family Doctor Can Safely Assist Many Births
Category: Health News
Created: 8/24/2015 12:00:00 AM
Last Editorial Review: 8/25/2015 12:00:00 AM

Title: Many Young Adults Think Hookahs, E-Cigs Safer Than Cigarettes
Category: Health News
Created: 8/25/2015 12:00:00 AM
Last Editorial Review: 8/26/2015 12:00:00 AM

Title: Think Safety When Picking, Packing School Backpacks
Category: Health News
Created: 8/19/2016 12:00:00 AM
Last Editorial Review: 8/22/2016 12:00:00 AM

Title: Doctors Divided on Safety, Use of Electronic Cigarettes
Category: Health News
Created: 8/26/2016 12:00:00 AM
Last Editorial Review: 8/26/2016 12:00:00 AM

Title: Health Tip: Food Safety for College Students
Category: Health News
Created: 9/1/2017 12:00:00 AM
Last Editorial Review: 9/1/2017 12:00:00 AM

Title: Health Tip: Stay Safe During a Lightning Storm
Category: Health News
Created: 9/1/2017 12:00:00 AM
Last Editorial Review: 9/1/2017 12:00:00 AM

Title: Health Tip: Food Safety for Pregnant and Nursing Mothers
Category: Health News
Created: 8/27/2018 12:00:00 AM
Last Editorial Review: 8/27/2018 12:00:00 AM

Title: Expert Advice for a Safe Trip Back to School
Category: Health News
Created: 8/27/2018 12:00:00 AM
Last Editorial Review: 8/28/2018 12:00:00 AM

Title: Teaching Your Kids Online Safety
Category: Health News
Created: 8/29/2018 12:00:00 AM
Last Editorial Review: 8/29/2018 12:00:00 AM

Title: Security Scanners Safe for Patients With Heart Devices: Study
Category: Health News
Created: 8/28/2018 12:00:00 AM
Last Editorial Review: 8/29/2018 12:00:00 AM

Title: Health Tip: Keep Your Epileptic Child Safer
Category: Health News
Created: 8/31/2018 12:00:00 AM
Last Editorial Review: 8/31/2018 12:00:00 AM

Title: Health Tip: Parking Lot Safety
Category: Health News
Created: 8/26/2019 12:00:00 AM
Last Editorial Review: 8/26/2019 12:00:00 AM

Title: Play It Safe With Allergies, Asthma During Pandemic School Year
Category: Health News
Created: 8/21/2020 12:00:00 AM
Last Editorial Review: 8/24/2020 12:00:00 AM

Title: There's No Safe Amount of Caffeine in Pregnancy: Report
Category: Health News
Created: 8/24/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM

Title: Cancer Radiation Can Safely Proceed During COVID-19 Pandemic: Study
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/28/2020 12:00:00 AM

Title: COVID Vaccine Safe for Pregnant Women: Study
Category: Health News
Created: 8/15/2022 12:00:00 AM
Last Editorial Review: 8/15/2022 12:00:00 AM

Title: Is Brown Rice Safe if You Have Diabetes?
Category: Health and Living
Created: 7/13/2022 12:00:00 AM
Last Editorial Review: 7/13/2022 12:00:00 AM

Title: U.S. Hospitals Are Getting Safer for Patients, Study Finds
Category: Health News
Created: 7/20/2022 12:00:00 AM
Last Editorial Review: 7/20/2022 12:00:00 AM

[¹⁷⁷Lu]Lu-PSMA-617 was approved by the U.S. Food and Drug Administration for patients with prostate-specific membrane antigen (PSMA)–positive metastatic castration-resistant prostate cancer (mCRPC). Since the time of regulatory approval, however, real-world data have been lacking. This study investigated the efficacy, safety, and outcome predictors of [¹⁷⁷Lu]Lu-PSMA-617 at a major U.S. academic center. Methods: Patients with mCRPC who received [¹⁷⁷Lu]Lu-PSMA-617 at the Johns Hopkins Hospital outside clinical trials were screened for inclusion. Patients who underwent [¹⁷⁷Lu]Lu-PSMA-617 and had available outcome data were included in this study. Outcome data included prostate-specific antigen (PSA) response (≥50% decline), PSA progression-free survival (PFS), and overall survival (OS). Toxicity data were evaluated according to the Common Terminology Criteria for Adverse Events version 5.03. The study tested the association of baseline circulating tumor DNA mutational status in homologous recombination repair, PI3K alteration pathway, and aggressive-variant prostate cancer–associated genes with treatment outcome. Baseline PSMA PET/CT images were analyzed using SelectPSMA, an artificial intelligence algorithm, to predict treatment outcome. Associations with the observed treatment outcome were evaluated. Results: All 76 patients with PSMA-positive mCRPC who received [¹⁷⁷Lu]Lu-PSMA-617 met the inclusion criteria. A PSA response was achieved in 30 of 74 (41%) patients. The median PSA PFS was 4.1 mo (95% CI, 2.0–6.2 mo), and the median OS was 13.7 mo (95% CI, 11.3–16.1 mo). Anemia of grade 3 or greater, thrombocytopenia, and neutropenia were observed in 9 (12%), 3 (4%), and 1 (1%), respectively, of 76 patients. Transient xerostomia was observed in 23 (28%) patients. The presence of aggressive-variant prostate cancer–associated genes was associated with a shorter PSA PFS (median, 1.3 vs. 6.3 mo; P = 0.040). No other associations were observed between circulating tumor DNA mutational status and treatment outcomes. Eighteen of 71 (25%) patients classified by SelectPSMA as nonresponders had significantly lower rates of PSA response than patients classified as likely responders (6% vs. 51%; P < 0.001), a shorter PSA PFS (median, 1.3 vs. 6.3 mo; P < 0.001), and a shorter OS (median, 6.3 vs. 14.5 mo; P = 0.046). Conclusion: [¹⁷⁷Lu]Lu-PSMA-617 offered in a real-world setting after regulatory approval in the United States demonstrated antitumor activity and a favorable toxicity profile. Artificial-intelligence–based analysis of baseline PSMA PET/CT images may improve patient selection. Validation of these findings on larger cohorts is warranted.

BackgroundCOVID-19 pandemic restrictions may have influenced behaviours related to weight.AimTo describe patterns of weight change among adults living in England with type 2 diabetes (T2D) and/or hypertension during the pandemic.Design and settingAn observational cohort study using the routinely collected health data of approximately 40% of adults living in England, accessed through the OpenSAFELY service inside TPP.MethodClinical and sociodemographic characteristics associated with rapid weight gain (>0.5 kg/m2/year) were investigated using multivariable logistic regression.ResultsData were extracted on adults with T2D (n = 1 231 455, 43.9% female, and 76.0% White British) or hypertension (n = 3 558 405, 49.7% female, and 84.3% White British). Adults with T2D lost weight overall (median δ = −0.1 kg/m2/year [interquartile range {IQR} −0.7–0.4]). However, rapid weight gain was common (20.7%) and associated with the following: sex (male versus female: adjusted odds ratio [aOR] 0.78 [95% confidence interval {CI} = 0.77 to 0.79]); age (older age reduced odds, for example, aged 60–69 years versus 18–29 years: aOR 0.66 [95% CI = 0.61 to 0.71]); deprivation (least deprived Index of Multiple Deprivation [IMD] quintile versus most deprived IMD quintile: aOR 0.87 [95% CI = 0.85 to 0.89]); White ethnicity (Black versus White: aOR 0.95 [95% CI = 0.92 to 0.98]); mental health conditions (for example, depression: aOR 1.13 [95% CI = 1.12 to 1.15]); and diabetes treatment (non-insulin treatment versus no pharmacological treatment: aOR 0.68 [95% CI = 0.67 to 0.69]). Adults with hypertension maintained stable weight overall (median δ = 0.0 kg/m2/year [IQR −0.6–0.5]); however, rapid weight gain was common (24.7%) and associated with similar characteristics as in T2D.ConclusionAmong adults living in England with T2D and/or hypertension, rapid pandemic weight gain was more common among females, younger adults, those living in more deprived areas, and those with mental health conditions.

PURPOSE

Currently, 40% of counties in the United States do not have an obstetrician or midwife, and in rural areas the likelihood of childbirth being attended to by a family medicine (FM) physician is increasing. We sought to characterize the effect of the FM presence on unit culture and a key perinatal quality metric in Iowa hospital intrapartum units.

A 10-year analysis of air accidents reveals good news for most passengers but worrying trends in training and drones.

Dangerous radiation reaches Mars at levels we aren't exposed to on Earth, which makes the Red Planet a particularly dangerous place to be during pregnancy

Every stock trader should consider a virtual private network to safeguard their trading, according to tech guru Kurt "CyberGuy" Knutsson.