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The nature and treatment of nonopiate abuse : a review of the literature. Volume 2 / Wynne Associates for Division of Research, National Institute on Drug Abuse, Alcohol, Drug Abuse and Mental Health Administration, Department of Health, Education and Wel

Washington, D.C. : Wynne Associates, 1974.




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Evaluation of treatment programs for abusers of nonopiate drugs : problems and approaches. Volume 3 / Wynne Associates for Division of Research, National Institute on Drug Abuse, Alcohol, Drug Abuse and Mental Health Administration, Department of Health,

Washington, D.C. : Wynne Associates, [1974]




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Sydney in 1848 : illustrated by copper-plate engravings of its principal streets, public buildings, churches, chapels, etc. / from drawings by Joseph Fowles.




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Nonparametric false discovery rate control for identifying simultaneous signals

Sihai Dave Zhao, Yet Tien Nguyen.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 110--142.

Abstract:
It is frequently of interest to identify simultaneous signals, defined as features that exhibit statistical significance across each of several independent experiments. For example, genes that are consistently differentially expressed across experiments in different animal species can reveal evolutionarily conserved biological mechanisms. However, in some problems the test statistics corresponding to these features can have complicated or unknown null distributions. This paper proposes a novel nonparametric false discovery rate control procedure that can identify simultaneous signals even without knowing these null distributions. The method is shown, theoretically and in simulations, to asymptotically control the false discovery rate. It was also used to identify genes that were both differentially expressed and proximal to differentially accessible chromatin in the brains of mice exposed to a conspecific intruder. The proposed method is available in the R package github.com/sdzhao/ssa.




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Rate optimal Chernoff bound and application to community detection in the stochastic block models

Zhixin Zhou, Ping Li.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1302--1347.

Abstract:
The Chernoff coefficient is known to be an upper bound of Bayes error probability in classification problem. In this paper, we will develop a rate optimal Chernoff bound on the Bayes error probability. The new bound is not only an upper bound but also a lower bound of Bayes error probability up to a constant factor. Moreover, we will apply this result to community detection in the stochastic block models. As a clustering problem, the optimal misclassification rate of community detection problem can be characterized by our rate optimal Chernoff bound. This can be formalized by deriving a minimax error rate over certain parameter space of stochastic block models, then achieving such an error rate by a feasible algorithm employing multiple steps of EM type updates.




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Perturbation Bounds for Procrustes, Classical Scaling, and Trilateration, with Applications to Manifold Learning

One of the common tasks in unsupervised learning is dimensionality reduction, where the goal is to find meaningful low-dimensional structures hidden in high-dimensional data. Sometimes referred to as manifold learning, this problem is closely related to the problem of localization, which aims at embedding a weighted graph into a low-dimensional Euclidean space. Several methods have been proposed for localization, and also manifold learning. Nonetheless, the robustness property of most of them is little understood. In this paper, we obtain perturbation bounds for classical scaling and trilateration, which are then applied to derive performance bounds for Isomap, Landmark Isomap, and Maximum Variance Unfolding. A new perturbation bound for procrustes analysis plays a key role.




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Derivative-Free Methods for Policy Optimization: Guarantees for Linear Quadratic Systems

We study derivative-free methods for policy optimization over the class of linear policies. We focus on characterizing the convergence rate of these methods when applied to linear-quadratic systems, and study various settings of driving noise and reward feedback. Our main theoretical result provides an explicit bound on the sample or evaluation complexity: we show that these methods are guaranteed to converge to within any pre-specified tolerance of the optimal policy with a number of zero-order evaluations that is an explicit polynomial of the error tolerance, dimension, and curvature properties of the problem. Our analysis reveals some interesting differences between the settings of additive driving noise and random initialization, as well as the settings of one-point and two-point reward feedback. Our theory is corroborated by simulations of derivative-free methods in application to these systems. Along the way, we derive convergence rates for stochastic zero-order optimization algorithms when applied to a certain class of non-convex problems.




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The Maximum Separation Subspace in Sufficient Dimension Reduction with Categorical Response

Sufficient dimension reduction (SDR) is a very useful concept for exploratory analysis and data visualization in regression, especially when the number of covariates is large. Many SDR methods have been proposed for regression with a continuous response, where the central subspace (CS) is the target of estimation. Various conditions, such as the linearity condition and the constant covariance condition, are imposed so that these methods can estimate at least a portion of the CS. In this paper we study SDR for regression and discriminant analysis with categorical response. Motivated by the exploratory analysis and data visualization aspects of SDR, we propose a new geometric framework to reformulate the SDR problem in terms of manifold optimization and introduce a new concept called Maximum Separation Subspace (MASES). The MASES naturally preserves the “sufficiency” in SDR without imposing additional conditions on the predictor distribution, and directly inspires a semi-parametric estimator. Numerical studies show MASES exhibits superior performance as compared with competing SDR methods in specific settings.




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On the Complexity Analysis of the Primal Solutions for the Accelerated Randomized Dual Coordinate Ascent

Dual first-order methods are essential techniques for large-scale constrained convex optimization. However, when recovering the primal solutions, we need $T(epsilon^{-2})$ iterations to achieve an $epsilon$-optimal primal solution when we apply an algorithm to the non-strongly convex dual problem with $T(epsilon^{-1})$ iterations to achieve an $epsilon$-optimal dual solution, where $T(x)$ can be $x$ or $sqrt{x}$. In this paper, we prove that the iteration complexity of the primal solutions and dual solutions have the same $Oleft(frac{1}{sqrt{epsilon}} ight)$ order of magnitude for the accelerated randomized dual coordinate ascent. When the dual function further satisfies the quadratic functional growth condition, by restarting the algorithm at any period, we establish the linear iteration complexity for both the primal solutions and dual solutions even if the condition number is unknown. When applied to the regularized empirical risk minimization problem, we prove the iteration complexity of $Oleft(nlog n+sqrt{frac{n}{epsilon}} ight)$ in both primal space and dual space, where $n$ is the number of samples. Our result takes out the $left(log frac{1}{epsilon} ight)$ factor compared with the methods based on smoothing/regularization or Catalyst reduction. As far as we know, this is the first time that the optimal $Oleft(sqrt{frac{n}{epsilon}} ight)$ iteration complexity in the primal space is established for the dual coordinate ascent based stochastic algorithms. We also establish the accelerated linear complexity for some problems with nonsmooth loss, e.g., the least absolute deviation and SVM.




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Greedy Attack and Gumbel Attack: Generating Adversarial Examples for Discrete Data

We present a probabilistic framework for studying adversarial attacks on discrete data. Based on this framework, we derive a perturbation-based method, Greedy Attack, and a scalable learning-based method, Gumbel Attack, that illustrate various tradeoffs in the design of attacks. We demonstrate the effectiveness of these methods using both quantitative metrics and human evaluation on various state-of-the-art models for text classification, including a word-based CNN, a character-based CNN and an LSTM. As an example of our results, we show that the accuracy of character-based convolutional networks drops to the level of random selection by modifying only five characters through Greedy Attack.




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Skill Rating for Multiplayer Games. Introducing Hypernode Graphs and their Spectral Theory

We consider the skill rating problem for multiplayer games, that is how to infer player skills from game outcomes in multiplayer games. We formulate the problem as a minimization problem $arg min_{s} s^T Delta s$ where $Delta$ is a positive semidefinite matrix and $s$ a real-valued function, of which some entries are the skill values to be inferred and other entries are constrained by the game outcomes. We leverage graph-based semi-supervised learning (SSL) algorithms for this problem. We apply our algorithms on several data sets of multiplayer games and obtain very promising results compared to Elo Duelling (see Elo, 1978) and TrueSkill (see Herbrich et al., 2006).. As we leverage graph-based SSL algorithms and because games can be seen as relations between sets of players, we then generalize the approach. For this aim, we introduce a new finite model, called hypernode graph, defined to be a set of weighted binary relations between sets of nodes. We define Laplacians of hypernode graphs. Then, we show that the skill rating problem for multiplayer games can be formulated as $arg min_{s} s^T Delta s$ where $Delta$ is the Laplacian of a hypernode graph constructed from a set of games. From a fundamental perspective, we show that hypernode graph Laplacians are symmetric positive semidefinite matrices with constant functions in their null space. We show that problems on hypernode graphs can not be solved with graph constructions and graph kernels. We relate hypernode graphs to signed graphs showing that positive relations between groups can lead to negative relations between individuals.




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Fast Rates for General Unbounded Loss Functions: From ERM to Generalized Bayes

We present new excess risk bounds for general unbounded loss functions including log loss and squared loss, where the distribution of the losses may be heavy-tailed. The bounds hold for general estimators, but they are optimized when applied to $eta$-generalized Bayesian, MDL, and empirical risk minimization estimators. In the case of log loss, the bounds imply convergence rates for generalized Bayesian inference under misspecification in terms of a generalization of the Hellinger metric as long as the learning rate $eta$ is set correctly. For general loss functions, our bounds rely on two separate conditions: the $v$-GRIP (generalized reversed information projection) conditions, which control the lower tail of the excess loss; and the newly introduced witness condition, which controls the upper tail. The parameter $v$ in the $v$-GRIP conditions determines the achievable rate and is akin to the exponent in the Tsybakov margin condition and the Bernstein condition for bounded losses, which the $v$-GRIP conditions generalize; favorable $v$ in combination with small model complexity leads to $ ilde{O}(1/n)$ rates. The witness condition allows us to connect the excess risk to an 'annealed' version thereof, by which we generalize several previous results connecting Hellinger and Rényi divergence to KL divergence.




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Cook commemoration sparks 1970 protest

In 1970, celebrations and commemorations were held across the nation for the 200th anniversary of the Endeavour’s visit




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Subjective Bayesian testing using calibrated prior probabilities

Dan J. Spitzner.

Source: Brazilian Journal of Probability and Statistics, Volume 33, Number 4, 861--893.

Abstract:
This article proposes a calibration scheme for Bayesian testing that coordinates analytically-derived statistical performance considerations with expert opinion. In other words, the scheme is effective and meaningful for incorporating objective elements into subjective Bayesian inference. It explores a novel role for default priors as anchors for calibration rather than substitutes for prior knowledge. Ideas are developed for use with multiplicity adjustments in multiple-model contexts, and to address the issue of prior sensitivity of Bayes factors. Along the way, the performance properties of an existing multiplicity adjustment related to the Poisson distribution are clarified theoretically. Connections of the overall calibration scheme to the Schwarz criterion are also explored. The proposed framework is examined and illustrated on a number of existing data sets related to problems in clinical trials, forensic pattern matching, and log-linear models methodology.




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Estimation of parameters in the $operatorname{DDRCINAR}(p)$ model

Xiufang Liu, Dehui Wang.

Source: Brazilian Journal of Probability and Statistics, Volume 33, Number 3, 638--673.

Abstract:
This paper discusses a $p$th-order dependence-driven random coefficient integer-valued autoregressive time series model ($operatorname{DDRCINAR}(p)$). Stationarity and ergodicity properties are proved. Conditional least squares, weighted least squares and maximum quasi-likelihood are used to estimate the model parameters. Asymptotic properties of the estimators are presented. The performances of these estimators are investigated and compared via simulations. In certain regions of the parameter space, simulative analysis shows that maximum quasi-likelihood estimators perform better than the estimators of conditional least squares and weighted least squares in terms of the proportion of within-$Omega$ estimates. At last, the model is applied to two real data sets.




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A temporal perspective on the rate of convergence in first-passage percolation under a moment condition

Daniel Ahlberg.

Source: Brazilian Journal of Probability and Statistics, Volume 33, Number 2, 397--401.

Abstract:
We study the rate of convergence in the celebrated Shape Theorem in first-passage percolation, obtaining the precise asymptotic rate of decay for the probability of linear order deviations under a moment condition. Our results are presented from a temporal perspective and complement previous work by the same author, in which the rate of convergence was studied from the standard spatial perspective.




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Failure rate of Birnbaum–Saunders distributions: Shape, change-point, estimation and robustness

Emilia Athayde, Assis Azevedo, Michelli Barros, Víctor Leiva.

Source: Brazilian Journal of Probability and Statistics, Volume 33, Number 2, 301--328.

Abstract:
The Birnbaum–Saunders (BS) distribution has been largely studied and applied. A random variable with BS distribution is a transformation of another random variable with standard normal distribution. Generalized BS distributions are obtained when the normally distributed random variable is replaced by another symmetrically distributed random variable. This allows us to obtain a wide class of positively skewed models with lighter and heavier tails than the BS model. Its failure rate admits several shapes, including the unimodal case, with its change-point being able to be used for different purposes. For example, to establish the reduction in a dose, and then in the cost of the medical treatment. We analyze the failure rates of generalized BS distributions obtained by the logistic, normal and Student-t distributions, considering their shape and change-point, estimating them, evaluating their robustness, assessing their performance by simulations, and applying the results to real data from different areas.




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Bayesian robustness to outliers in linear regression and ratio estimation

Alain Desgagné, Philippe Gagnon.

Source: Brazilian Journal of Probability and Statistics, Volume 33, Number 2, 205--221.

Abstract:
Whole robustness is a nice property to have for statistical models. It implies that the impact of outliers gradually vanishes as they approach plus or minus infinity. So far, the Bayesian literature provides results that ensure whole robustness for the location-scale model. In this paper, we make two contributions. First, we generalise the results to attain whole robustness in simple linear regression through the origin, which is a necessary step towards results for general linear regression models. We allow the variance of the error term to depend on the explanatory variable. This flexibility leads to the second contribution: we provide a simple Bayesian approach to robustly estimate finite population means and ratios. The strategy to attain whole robustness is simple since it lies in replacing the traditional normal assumption on the error term by a super heavy-tailed distribution assumption. As a result, users can estimate the parameters as usual, using the posterior distribution.




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Nights below Foord Street : literature and popular culture in postindustrial Nova Scotia

Thompson, Peter, 1981- author.
0773559345




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Novel bodies : disability and sexuality in eighteenth-century British literature

Farr, Jason S., 1978- author.
9781684481088 hardcover alkaline paper




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Errata: A survey of Bayesian predictive methods for model assessment, selection and comparison

Aki Vehtari, Janne Ojanen.

Source: Statistics Surveys, Volume 8, , 1--1.

Abstract:
Errata for “A survey of Bayesian predictive methods for model assessment, selection and comparison” by A. Vehtari and J. Ojanen, Statistics Surveys , 6 (2012), 142–228. doi:10.1214/12-SS102.




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Identifying the consequences of dynamic treatment strategies: A decision-theoretic overview

A. Philip Dawid, Vanessa Didelez

Source: Statist. Surv., Volume 4, 184--231.

Abstract:
We consider the problem of learning about and comparing the consequences of dynamic treatment strategies on the basis of observational data. We formulate this within a probabilistic decision-theoretic framework. Our approach is compared with related work by Robins and others: in particular, we show how Robins’s ‘ G -computation’ algorithm arises naturally from this decision-theoretic perspective. Careful attention is paid to the mathematical and substantive conditions required to justify the use of this formula. These conditions revolve around a property we term stability , which relates the probabilistic behaviours of observational and interventional regimes. We show how an assumption of ‘sequential randomization’ (or ‘no unmeasured confounders’), or an alternative assumption of ‘sequential irrelevance’, can be used to infer stability. Probabilistic influence diagrams are used to simplify manipulations, and their power and limitations are discussed. We compare our approach with alternative formulations based on causal DAGs or potential response models. We aim to show that formulating the problem of assessing dynamic treatment strategies as a problem of decision analysis brings clarity, simplicity and generality.

References:
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Dawid, A. P. (2000). Causal inference without counterfactuals (with Discussion). Journal of the American Statistical Association 95 407–448.

Dawid, A. P. (2001). Separoids: A mathematical framework for conditional independence and irrelevance. Annals of Mathematics and Artificial Intelligence 32 335–372.

Dawid, A. P. (2002). Influence diagrams for causal modelling and inference. International Statistical Review 70 161–189. Corrigenda, ibid ., 437.

Dawid, A. P. (2003). Causal inference using influence diagrams: The problem of partial compliance (with Discussion). In Highly Structured Stochastic Systems ( P. J. Green, N. L. Hjort and S. Richardson, eds.) 45–81. Oxford University Press.

Dawid, A. P. (2010). Beware of the DAG! In Proceedings of the NIPS 2008 Workshop on Causality. Journal of Machine Learning Research Workshop and Conference Proceedings ( D. Janzing, I. Guyon and B. Schölkopf, eds.) 6 59–86. http://tinyurl.com/33va7tm

Dawid, A. P. and Didelez, V. (2008). Identifying optimal sequential decisions. In Proceedings of the Twenty-Fourth Annual Conference on Uncertainty in Artificial Intelligence (UAI-08) ( D. McAllester and A. Nicholson, eds.). 113-120. AUAI Press, Corvallis, Oregon. http://tinyurl.com/3899qpp

Dechter, R. (2003). Constraint Processing. Morgan Kaufmann Publishers.

Didelez, V., Dawid, A. P. and Geneletti, S. G. (2006). Direct and indirect effects of sequential treatments. In Proceedings of the Twenty-Second Annual Conference on Uncertainty in Artificial Intelligence (UAI-06) ( R. Dechter and T. Richardson, eds.). 138-146. AUAI Press, Arlington, Virginia. http://tinyurl.com/32w3f4e

Didelez, V., Kreiner, S. and Keiding, N. (2010). Graphical models for inference under outcome dependent sampling. Statistical Science (to appear).

Didelez, V. and Sheehan, N. S. (2007). Mendelian randomisation: Why epidemiology needs a formal language for causality. In Causality and Probability in the Sciences, ( F. Russo and J. Williamson, eds.). Texts in Philosophy Series 5 263–292. College Publications, London.

Eichler, M. and Didelez, V. (2010). Granger-causality and the effect of interventions in time series. Lifetime Data Analysis 16 3–32.

Ferguson, T. S. (1967). Mathematical Statistics: A Decision Theoretic Approach. Academic Press, New York, London.

Geneletti, S. G. (2007). Identifying direct and indirect effects in a non–counterfactual framework. Journal of the Royal Statistical Society: Series B 69 199–215.

Geneletti, S. G. and Dawid, A. P. (2010). Defining and identifying the effect of treatment on the treated. In Causality in the Sciences ( P. M. Illari, F. Russo and J. Williamson, eds.) Oxford University Press (to appear).

Gill, R. D. and Robins, J. M. (2001). Causal inference for complex longitudinal data: The continuous case. Annals of Statistics 29 1785–1811.

Guo, H. and Dawid, A. P. (2010). Sufficient covariates and linear propensity analysis. In Proceedings of the Thirteenth International Workshop on Artificial Intelligence and Statistics, (AISTATS) 2010, Chia Laguna, Sardinia, Italy, May 13-15, 2010. Journal of Machine Learning Research Workshop and Conference Proceedings ( Y. W. Teh and D. M. Titterington, eds.) 9 281–288. http://tinyurl.com/33lmuj7

Henderson, R., Ansel, P. and Alshibani, D. (2010). Regret-regression for optimal dynamic treatment regimes. Biometrics (to appear). doi:10.1111/j.1541-0420.2009.01368.x

Hernán, M. A. and Taubman, S. L. (2008). Does obesity shorten life? The importance of well defined interventions to answer causal questions. International Journal of Obesity 32 S8–S14.

Holland, P. W. (1986). Statistics and causal inference (with Discussion). Journal of the American Statistical Association 81 945–970.

Huang, Y. and Valtorta, M. (2006). Identifiability in causal Bayesian networks: A sound and complete algorithm. In AAAI’06: Proceedings of the 21st National Conference on Artificial Intelligence 1149–1154. AAAI Press.

Kang, J. D. Y. and Schafer, J. L. (2007). Demystifying double robustness: A comparison of alternative strategies for estimating a population mean from incomplete data. Statistical Science 22 523–539.

Lauritzen, S. L., Dawid, A. P., Larsen, B. N. and Leimer, H. G. (1990). Independence properties of directed Markov fields. Networks 20 491–505.

Lok, J., Gill, R., van der Vaart, A. and Robins, J. (2004). Estimating the causal effect of a time-varying treatment on time-to-event using structural nested failure time models. Statistica Neerlandica 58 271–295.

Moodie, E. M., Richardson, T. S. and Stephens, D. A. (2007). Demystifying optimal dynamic treatment regimes. Biometrics 63 447–455.

Murphy, S. A. (2003). Optimal dynamic treatment regimes (with Discussion). Journal of the Royal Statistical Society, Series B 65 331-366.

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Pearl, J. (1995). Causal diagrams for empirical research (with Discussion). Biometrika 82 669-710.

Pearl, J. (2009). Causality: Models, Reasoning and Inference, Second ed. Cambridge University Press, Cambridge.

Pearl, J. and Paz, A. (1987). Graphoids: A graph-based logic for reasoning about relevance relations. In Advances in Artificial Intelligence ( D. Hogg and L. Steels, eds.) II 357–363. North-Holland, Amsterdam.

Pearl, J. and Robins, J. (1995). Probabilistic evaluation of sequential plans from causal models with hidden variables. In Proceedings of the 11th Conference on Uncertainty in Artificial Intelligence ( P. Besnard and S. Hanks, eds.) 444–453. Morgan Kaufmann Publishers, San Francisco.

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Robins, J. M. (1986). A new approach to causal inference in mortality studies with sustained exposure periods—Application to control of the healthy worker survivor effect. Mathematical Modelling 7 1393–1512.

Robins, J. M. (1987). Addendum to “A new approach to causal inference in mortality studies with sustained exposure periods—Application to control of the healthy worker survivor effect”. Computers & Mathematics with Applications 14 923–945.

Robins, J. M. (1989). The analysis of randomized and nonrandomized AIDS treatment trials using a new approach to causal inference in longitudinal studies. In Health Service Research Methodology: A Focus on AIDS ( L. Sechrest, H. Freeman and A. Mulley, eds.) 113–159. NCSHR, U.S. Public Health Service.

Robins, J. M. (1992). Estimation of the time-dependent accelerated failure time model in the presence of confounding factors. Biometrika 79 321–324.

Robins, J. M. (1997). Causal inference from complex longitudinal data. In Latent Variable Modeling and Applications to Causality, ( M. Berkane, ed.). Lecture Notes in Statistics 120 69–117. Springer-Verlag, New York.

Robins, J. M. (1998). Structural nested failure time models. In Survival Analysis, ( P. K. Andersen and N. Keiding, eds.). Encyclopedia of Biostatistics 6 4372–4389. John Wiley and Sons, Chichester, UK.

Robins, J. M. (2000). Robust estimation in sequentially ignorable missing data and causal inference models. In Proceedings of the American Statistical Association Section on Bayesian Statistical Science 1999 6–10.

Robins, J. M. (2004). Optimal structural nested models for optimal sequential decisions. In Proceedings of the Second Seattle Symposium on Biostatistics ( D. Y. Lin and P. Heagerty, eds.) 189–326. Springer, New York.

Robins, J. M., Greenland, S. and Hu, F. C. (1999). Estimation of the causal effect of a time-varying exposure on the marginal mean of a repeated binary outcome. Journal of the American Statistical Association 94 687–700.

Robins, J. M., Hernán, M. A. and Brumback, B. (2000). Marginal structural models and causal inference in epidemiology. Epidemiology 11 550–560.

Robins, J. M. and Wasserman, L. A. (1997). Estimation of effects of sequential treatments by reparameterizing directed acyclic graphs. In Proceedings of the 13th Annual Conference on Uncertainty in Artificial Intelligence ( D. Geiger and P. Shenoy, eds.) 409-420. Morgan Kaufmann Publishers, San Francisco. http://tinyurl.com/33ghsas

Rosthøj, S., Fullwood, C., Henderson, R. and Stewart, S. (2006). Estimation of optimal dynamic anticoagulation regimes from observational data: A regret-based approach. Statistics in Medicine 25 4197–4215.

Shpitser, I. and Pearl, J. (2006a). Identification of conditional interventional distributions. In Proceedings of the 22nd Annual Conference on Uncertainty in Artificial Intelligence (UAI-06) ( R. Dechter and T. Richardson, eds.). 437–444. AUAI Press, Corvallis, Oregon. http://tinyurl.com/2um8w47

Shpitser, I. and Pearl, J. (2006b). Identification of joint interventional distributions in recursive semi-Markovian causal models. In Proceedings of the Twenty-First National Conference on Artificial Intelligence 1219–1226. AAAI Press, Menlo Park, California.

Spirtes, P., Glymour, C. and Scheines, R. (2000). Causation, Prediction and Search, Second ed. Springer-Verlag, New York.

Sterne, J. A. C., May, M., Costagliola, D., de Wolf, F., Phillips, A. N., Harris, R., Funk, M. J., Geskus, R. B., Gill, J., Dabis, F., Miro, J. M., Justice, A. C., Ledergerber, B., Fatkenheuer, G., Hogg, R. S., D’Arminio-Monforte, A., Saag, M., Smith, C., Staszewski, S., Egger, M., Cole, S. R. and When To Start Consortium (2009). Timing of initiation of antiretroviral therapy in AIDS-Free HIV-1-infected patients: A collaborative analysis of 18 HIV cohort studies. Lancet 373 1352–1363.

Taubman, S. L., Robins, J. M., Mittleman, M. A. and Hernán, M. A. (2009). Intervening on risk factors for coronary heart disease: An application of the parametric g-formula. International Journal of Epidemiology 38 1599–1611.

Tian, J. (2008). Identifying dynamic sequential plans. In Proceedings of the Twenty-Fourth Annual Conference on Uncertainty in Artificial Intelligence (UAI-08) ( D. McAllester and A. Nicholson, eds.). 554–561. AUAI Press, Corvallis, Oregon. http://tinyurl.com/36ufx2h

Verma, T. and Pearl, J. (1990). Causal networks: Semantics and expressiveness. In Uncertainty in Artificial Intelligence 4 ( R. D. Shachter, T. S. Levitt, L. N. Kanal and J. F. Lemmer, eds.) 69–76. North-Holland, Amsterdam.




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Generating Thermal Image Data Samples using 3D Facial Modelling Techniques and Deep Learning Methodologies. (arXiv:2005.01923v2 [cs.CV] UPDATED)

Methods for generating synthetic data have become of increasing importance to build large datasets required for Convolution Neural Networks (CNN) based deep learning techniques for a wide range of computer vision applications. In this work, we extend existing methodologies to show how 2D thermal facial data can be mapped to provide 3D facial models. For the proposed research work we have used tufts datasets for generating 3D varying face poses by using a single frontal face pose. The system works by refining the existing image quality by performing fusion based image preprocessing operations. The refined outputs have better contrast adjustments, decreased noise level and higher exposedness of the dark regions. It makes the facial landmarks and temperature patterns on the human face more discernible and visible when compared to original raw data. Different image quality metrics are used to compare the refined version of images with original images. In the next phase of the proposed study, the refined version of images is used to create 3D facial geometry structures by using Convolution Neural Networks (CNN). The generated outputs are then imported in blender software to finally extract the 3D thermal facial outputs of both males and females. The same technique is also used on our thermal face data acquired using prototype thermal camera (developed under Heliaus EU project) in an indoor lab environment which is then used for generating synthetic 3D face data along with varying yaw face angles and lastly facial depth map is generated.




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Interpreting Rate-Distortion of Variational Autoencoder and Using Model Uncertainty for Anomaly Detection. (arXiv:2005.01889v2 [cs.LG] UPDATED)

Building a scalable machine learning system for unsupervised anomaly detection via representation learning is highly desirable. One of the prevalent methods is using a reconstruction error from variational autoencoder (VAE) via maximizing the evidence lower bound. We revisit VAE from the perspective of information theory to provide some theoretical foundations on using the reconstruction error, and finally arrive at a simpler and more effective model for anomaly detection. In addition, to enhance the effectiveness of detecting anomalies, we incorporate a practical model uncertainty measure into the metric. We show empirically the competitive performance of our approach on benchmark datasets.




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A Critical Overview of Privacy-Preserving Approaches for Collaborative Forecasting. (arXiv:2004.09612v3 [cs.LG] UPDATED)

Cooperation between different data owners may lead to an improvement in forecast quality - for instance by benefiting from spatial-temporal dependencies in geographically distributed time series. Due to business competitive factors and personal data protection questions, said data owners might be unwilling to share their data, which increases the interest in collaborative privacy-preserving forecasting. This paper analyses the state-of-the-art and unveils several shortcomings of existing methods in guaranteeing data privacy when employing Vector Autoregressive (VAR) models. The paper also provides mathematical proofs and numerical analysis to evaluate existing privacy-preserving methods, dividing them into three groups: data transformation, secure multi-party computations, and decomposition methods. The analysis shows that state-of-the-art techniques have limitations in preserving data privacy, such as a trade-off between privacy and forecasting accuracy, while the original data in iterative model fitting processes, in which intermediate results are shared, can be inferred after some iterations.




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Convergence rates for optimised adaptive importance samplers. (arXiv:1903.12044v4 [stat.CO] UPDATED)

Adaptive importance samplers are adaptive Monte Carlo algorithms to estimate expectations with respect to some target distribution which extit{adapt} themselves to obtain better estimators over a sequence of iterations. Although it is straightforward to show that they have the same $mathcal{O}(1/sqrt{N})$ convergence rate as standard importance samplers, where $N$ is the number of Monte Carlo samples, the behaviour of adaptive importance samplers over the number of iterations has been left relatively unexplored. In this work, we investigate an adaptation strategy based on convex optimisation which leads to a class of adaptive importance samplers termed extit{optimised adaptive importance samplers} (OAIS). These samplers rely on the iterative minimisation of the $chi^2$-divergence between an exponential-family proposal and the target. The analysed algorithms are closely related to the class of adaptive importance samplers which minimise the variance of the weight function. We first prove non-asymptotic error bounds for the mean squared errors (MSEs) of these algorithms, which explicitly depend on the number of iterations and the number of samples together. The non-asymptotic bounds derived in this paper imply that when the target belongs to the exponential family, the $L_2$ errors of the optimised samplers converge to the optimal rate of $mathcal{O}(1/sqrt{N})$ and the rate of convergence in the number of iterations are explicitly provided. When the target does not belong to the exponential family, the rate of convergence is the same but the asymptotic $L_2$ error increases by a factor $sqrt{ ho^star} > 1$, where $ ho^star - 1$ is the minimum $chi^2$-divergence between the target and an exponential-family proposal.




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Nonstationary Bayesian modeling for a large data set of derived surface temperature return values. (arXiv:2005.03658v1 [stat.ME])

Heat waves resulting from prolonged extreme temperatures pose a significant risk to human health globally. Given the limitations of observations of extreme temperature, climate models are often used to characterize extreme temperature globally, from which one can derive quantities like return values to summarize the magnitude of a low probability event for an arbitrary geographic location. However, while these derived quantities are useful on their own, it is also often important to apply a spatial statistical model to such data in order to, e.g., understand how the spatial dependence properties of the return values vary over space and emulate the climate model for generating additional spatial fields with corresponding statistical properties. For these objectives, when modeling global data it is critical to use a nonstationary covariance function. Furthermore, given that the output of modern global climate models can be on the order of $mathcal{O}(10^4)$, it is important to utilize approximate Gaussian process methods to enable inference. In this paper, we demonstrate the application of methodology introduced in Risser and Turek (2020) to conduct a nonstationary and fully Bayesian analysis of a large data set of 20-year return values derived from an ensemble of global climate model runs with over 50,000 spatial locations. This analysis uses the freely available BayesNSGP software package for R.




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Generative Feature Replay with Orthogonal Weight Modification for Continual Learning. (arXiv:2005.03490v1 [cs.LG])

The ability of intelligent agents to learn and remember multiple tasks sequentially is crucial to achieving artificial general intelligence. Many continual learning (CL) methods have been proposed to overcome catastrophic forgetting. Catastrophic forgetting notoriously impedes the sequential learning of neural networks as the data of previous tasks are unavailable. In this paper we focus on class incremental learning, a challenging CL scenario, in which classes of each task are disjoint and task identity is unknown during test. For this scenario, generative replay is an effective strategy which generates and replays pseudo data for previous tasks to alleviate catastrophic forgetting. However, it is not trivial to learn a generative model continually for relatively complex data. Based on recently proposed orthogonal weight modification (OWM) algorithm which can keep previously learned input-output mappings invariant approximately when learning new tasks, we propose to directly generate and replay feature. Empirical results on image and text datasets show our method can improve OWM consistently by a significant margin while conventional generative replay always results in a negative effect. Our method also beats a state-of-the-art generative replay method and is competitive with a strong baseline based on real data storage.




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A stochastic user-operator assignment game for microtransit service evaluation: A case study of Kussbus in Luxembourg. (arXiv:2005.03465v1 [physics.soc-ph])

This paper proposes a stochastic variant of the stable matching model from Rasulkhani and Chow [1] which allows microtransit operators to evaluate their operation policy and resource allocations. The proposed model takes into account the stochastic nature of users' travel utility perception, resulting in a probabilistic stable operation cost allocation outcome to design ticket price and ridership forecasting. We applied the model for the operation policy evaluation of a microtransit service in Luxembourg and its border area. The methodology for the model parameters estimation and calibration is developed. The results provide useful insights for the operator and the government to improve the ridership of the service.




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Fair Algorithms for Hierarchical Agglomerative Clustering. (arXiv:2005.03197v1 [cs.LG])

Hierarchical Agglomerative Clustering (HAC) algorithms are extensively utilized in modern data science and machine learning, and seek to partition the dataset into clusters while generating a hierarchical relationship between the data samples themselves. HAC algorithms are employed in a number of applications, such as biology, natural language processing, and recommender systems. Thus, it is imperative to ensure that these algorithms are fair-- even if the dataset contains biases against certain protected groups, the cluster outputs generated should not be discriminatory against samples from any of these groups. However, recent work in clustering fairness has mostly focused on center-based clustering algorithms, such as k-median and k-means clustering. Therefore, in this paper, we propose fair algorithms for performing HAC that enforce fairness constraints 1) irrespective of the distance linkage criteria used, 2) generalize to any natural measures of clustering fairness for HAC, 3) work for multiple protected groups, and 4) have competitive running times to vanilla HAC. To the best of our knowledge, this is the first work that studies fairness for HAC algorithms. We also propose an algorithm with lower asymptotic time complexity than HAC algorithms that can rectify existing HAC outputs and make them subsequently fair as a result. Moreover, we carry out extensive experiments on multiple real-world UCI datasets to demonstrate the working of our algorithms.




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Vertebrate and invertebrate respiratory proteins, lipoproteins and other body fluid proteins

9783030417697 (electronic bk.)




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Racing for the surface : pathogenesis of implant infection and advanced antimicrobial strategies

9783030344757 (electronic bk.)




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Pediatric restorative dentistry

9783319934266 (electronic bk.)




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Mental Conditioning to Perform Common Operations in General Surgery Training

9783319911649 978-3-319-91164-9




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Mayo Clinic strategies to reduce burnout : 12 actions to create the ideal workplace

Swensen, Stephen J., author.
9780190848996 electronic book




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Invertebrate embryology and reproduction

El-Bawab, Fatma, author.
9780128141151 (electronic bk.)




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Integrated pest and disease management in greenhouse crops

9783030223045 electronic book




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Insect collection and identification : techniques for the field and laboratory

Gibb, Timothy J., author.
9780128165713 (ePub ebook)




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In china's wake : how the commodity boom transformed development strategies in the global south

Jepson, Nicholas, author.
9780231547598 electronic book




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Extra-coronal restorations : concepts and clinical application

9783319790930 (electronic bk.)




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Ecology, conservation, and restoration of Chilika Lagoon, India

9783030334246 (electronic bk.)




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Conservation genetics in mammals : integrative research using novel approaches

9783030333348 (electronic bk.)




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Clinical approaches in endodontic regeneration : current and emerging therapeutic perspectives

9783319968483 (electronic bk.)




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Agri-food industry strategies for healthy diets and sustainability : new challenges in nutrition and public health

9780128172261




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Concentration and consistency results for canonical and curved exponential-family models of random graphs

Michael Schweinberger, Jonathan Stewart.

Source: The Annals of Statistics, Volume 48, Number 1, 374--396.

Abstract:
Statistical inference for exponential-family models of random graphs with dependent edges is challenging. We stress the importance of additional structure and show that additional structure facilitates statistical inference. A simple example of a random graph with additional structure is a random graph with neighborhoods and local dependence within neighborhoods. We develop the first concentration and consistency results for maximum likelihood and $M$-estimators of a wide range of canonical and curved exponential-family models of random graphs with local dependence. All results are nonasymptotic and applicable to random graphs with finite populations of nodes, although asymptotic consistency results can be obtained as well. In addition, we show that additional structure can facilitate subgraph-to-graph estimation, and present concentration results for subgraph-to-graph estimators. As an application, we consider popular curved exponential-family models of random graphs, with local dependence induced by transitivity and parameter vectors whose dimensions depend on the number of nodes.




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Optimal rates for community estimation in the weighted stochastic block model

Min Xu, Varun Jog, Po-Ling Loh.

Source: The Annals of Statistics, Volume 48, Number 1, 183--204.

Abstract:
Community identification in a network is an important problem in fields such as social science, neuroscience and genetics. Over the past decade, stochastic block models (SBMs) have emerged as a popular statistical framework for this problem. However, SBMs have an important limitation in that they are suited only for networks with unweighted edges; in various scientific applications, disregarding the edge weights may result in a loss of valuable information. We study a weighted generalization of the SBM, in which observations are collected in the form of a weighted adjacency matrix and the weight of each edge is generated independently from an unknown probability density determined by the community membership of its endpoints. We characterize the optimal rate of misclustering error of the weighted SBM in terms of the Renyi divergence of order 1/2 between the weight distributions of within-community and between-community edges, substantially generalizing existing results for unweighted SBMs. Furthermore, we present a computationally tractable algorithm based on discretization that achieves the optimal error rate. Our method is adaptive in the sense that the algorithm, without assuming knowledge of the weight densities, performs as well as the best algorithm that knows the weight densities.




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Sparse SIR: Optimal rates and adaptive estimation

Kai Tan, Lei Shi, Zhou Yu.

Source: The Annals of Statistics, Volume 48, Number 1, 64--85.

Abstract:
Sliced inverse regression (SIR) is an innovative and effective method for sufficient dimension reduction and data visualization. Recently, an impressive range of penalized SIR methods has been proposed to estimate the central subspace in a sparse fashion. Nonetheless, few of them considered the sparse sufficient dimension reduction from a decision-theoretic point of view. To address this issue, we in this paper establish the minimax rates of convergence for estimating the sparse SIR directions under various commonly used loss functions in the literature of sufficient dimension reduction. We also discover the possible trade-off between statistical guarantee and computational performance for sparse SIR. We finally propose an adaptive estimation scheme for sparse SIR which is computationally tractable and rate optimal. Numerical studies are carried out to confirm the theoretical properties of our proposed methods.




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Minimax posterior convergence rates and model selection consistency in high-dimensional DAG models based on sparse Cholesky factors

Kyoungjae Lee, Jaeyong Lee, Lizhen Lin.

Source: The Annals of Statistics, Volume 47, Number 6, 3413--3437.

Abstract:
In this paper we study the high-dimensional sparse directed acyclic graph (DAG) models under the empirical sparse Cholesky prior. Among our results, strong model selection consistency or graph selection consistency is obtained under more general conditions than those in the existing literature. Compared to Cao, Khare and Ghosh [ Ann. Statist. (2019) 47 319–348], the required conditions are weakened in terms of the dimensionality, sparsity and lower bound of the nonzero elements in the Cholesky factor. Furthermore, our result does not require the irrepresentable condition, which is necessary for Lasso-type methods. We also derive the posterior convergence rates for precision matrices and Cholesky factors with respect to various matrix norms. The obtained posterior convergence rates are the fastest among those of the existing Bayesian approaches. In particular, we prove that our posterior convergence rates for Cholesky factors are the minimax or at least nearly minimax depending on the relative size of true sparseness for the entire dimension. The simulation study confirms that the proposed method outperforms the competing methods.




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An operator theoretic approach to nonparametric mixture models

Robert A. Vandermeulen, Clayton D. Scott.

Source: The Annals of Statistics, Volume 47, Number 5, 2704--2733.

Abstract:
When estimating finite mixture models, it is common to make assumptions on the mixture components, such as parametric assumptions. In this work, we make no distributional assumptions on the mixture components and instead assume that observations from the mixture model are grouped, such that observations in the same group are known to be drawn from the same mixture component. We precisely characterize the number of observations $n$ per group needed for the mixture model to be identifiable, as a function of the number $m$ of mixture components. In addition to our assumption-free analysis, we also study the settings where the mixture components are either linearly independent or jointly irreducible. Furthermore, our analysis considers two kinds of identifiability, where the mixture model is the simplest one explaining the data, and where it is the only one. As an application of these results, we precisely characterize identifiability of multinomial mixture models. Our analysis relies on an operator-theoretic framework that associates mixture models in the grouped-sample setting with certain infinite-dimensional tensors. Based on this framework, we introduce a general spectral algorithm for recovering the mixture components.




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Convergence rates of least squares regression estimators with heavy-tailed errors

Qiyang Han, Jon A. Wellner.

Source: The Annals of Statistics, Volume 47, Number 4, 2286--2319.

Abstract:
We study the performance of the least squares estimator (LSE) in a general nonparametric regression model, when the errors are independent of the covariates but may only have a $p$th moment ($pgeq1$). In such a heavy-tailed regression setting, we show that if the model satisfies a standard “entropy condition” with exponent $alphain(0,2)$, then the $L_{2}$ loss of the LSE converges at a rate [mathcal{O}_{mathbf{P}}igl(n^{-frac{1}{2+alpha}}vee n^{-frac{1}{2}+frac{1}{2p}}igr).] Such a rate cannot be improved under the entropy condition alone. This rate quantifies both some positive and negative aspects of the LSE in a heavy-tailed regression setting. On the positive side, as long as the errors have $pgeq1+2/alpha$ moments, the $L_{2}$ loss of the LSE converges at the same rate as if the errors are Gaussian. On the negative side, if $p<1+2/alpha$, there are (many) hard models at any entropy level $alpha$ for which the $L_{2}$ loss of the LSE converges at a strictly slower rate than other robust estimators. The validity of the above rate relies crucially on the independence of the covariates and the errors. In fact, the $L_{2}$ loss of the LSE can converge arbitrarily slowly when the independence fails. The key technical ingredient is a new multiplier inequality that gives sharp bounds for the “multiplier empirical process” associated with the LSE. We further give an application to the sparse linear regression model with heavy-tailed covariates and errors to demonstrate the scope of this new inequality.