hear Cardiac Rehab Boosts Quality of Life After Heart Attack: Study By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Cardiac Rehab Boosts Quality of Life After Heart Attack: StudyCategory: Health NewsCreated: 4/27/2020 12:00:00 AMLast Editorial Review: 4/28/2020 12:00:00 AM Full Article
hear During Coronavirus Pandemic, Don't Ignore Symptoms of Heart Attack, Stroke By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: During Coronavirus Pandemic, Don't Ignore Symptoms of Heart Attack, StrokeCategory: Health NewsCreated: 4/30/2020 12:00:00 AMLast Editorial Review: 4/30/2020 12:00:00 AM Full Article
hear COVID-19 May Be Causing Kawasaki Disease Heart Condition in Kids By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: COVID-19 May Be Causing Kawasaki Disease Heart Condition in KidsCategory: Health NewsCreated: 4/29/2020 12:00:00 AMLast Editorial Review: 4/30/2020 12:00:00 AM Full Article
hear When Young Adults Vape, Blood Pressure, Heart Rate May Spike By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: When Young Adults Vape, Blood Pressure, Heart Rate May SpikeCategory: Health NewsCreated: 4/30/2020 12:00:00 AMLast Editorial Review: 5/1/2020 12:00:00 AM Full Article
hear AHA News: How Pregnant Woman's High Blood Pressure Can Change Shape of Baby's Heart By www.medicinenet.com Published On :: Fri, 1 May 2020 00:00:00 PDT Title: AHA News: How Pregnant Woman's High Blood Pressure Can Change Shape of Baby's HeartCategory: Health NewsCreated: 4/30/2020 12:00:00 AMLast Editorial Review: 5/1/2020 12:00:00 AM Full Article
hear AHA News: More Intense Blood Pressure Control May Lower Irregular Heartbeat Risk By www.medicinenet.com Published On :: Tue, 5 May 2020 00:00:00 PDT Title: AHA News: More Intense Blood Pressure Control May Lower Irregular Heartbeat RiskCategory: Health NewsCreated: 5/4/2020 12:00:00 AMLast Editorial Review: 5/5/2020 12:00:00 AM Full Article
hear Key Areas of the Brain Triggered in Recent Heart Attack Survivors By www.medicinenet.com Published On :: Wed, 6 May 2020 00:00:00 PDT Title: Key Areas of the Brain Triggered in Recent Heart Attack SurvivorsCategory: Health NewsCreated: 5/5/2020 12:00:00 AMLast Editorial Review: 5/6/2020 12:00:00 AM Full Article
hear FDA OKs Farxiga for Heart Failure With Reduced Ejection Fraction By www.medicinenet.com Published On :: Thu, 7 May 2020 00:00:00 PDT Title: FDA OKs Farxiga for Heart Failure With Reduced Ejection FractionCategory: Health NewsCreated: 5/6/2020 12:00:00 AMLast Editorial Review: 5/7/2020 12:00:00 AM Full Article
hear Tough Childhoods Are Tough on Adult Hearts: Study By www.medicinenet.com Published On :: Thu, 7 May 2020 00:00:00 PDT Title: Tough Childhoods Are Tough on Adult Hearts: StudyCategory: Health NewsCreated: 5/6/2020 12:00:00 AMLast Editorial Review: 5/7/2020 12:00:00 AM Full Article
hear What Is PDA Heart Surgery? By www.medicinenet.com Published On :: Fri, 8 May 2020 00:00:00 PDT Title: What Is PDA Heart Surgery?Category: Procedures and TestsCreated: 5/8/2020 12:00:00 AMLast Editorial Review: 5/8/2020 12:00:00 AM Full Article
hear What Is a Transradial Heart Catheterization Procedure? By www.medicinenet.com Published On :: Fri, 8 May 2020 00:00:00 PDT Title: What Is a Transradial Heart Catheterization Procedure?Category: Procedures and TestsCreated: 5/8/2020 12:00:00 AMLast Editorial Review: 5/8/2020 12:00:00 AM Full Article
hear AHA News: Traumatic Childhood Increases Lifelong Risk for Heart Disease, Early Death By www.medicinenet.com Published On :: Wed, 29 Apr 2020 00:00:00 PDT Title: AHA News: Traumatic Childhood Increases Lifelong Risk for Heart Disease, Early DeathCategory: Health NewsCreated: 4/28/2020 12:00:00 AMLast Editorial Review: 4/29/2020 12:00:00 AM Full Article
hear Condition Affecting Kids With COVID-19 Remains Very Rare, Heart Group Says By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Condition Affecting Kids With COVID-19 Remains Very Rare, Heart Group SaysCategory: Health NewsCreated: 5/7/2020 12:00:00 AMLast Editorial Review: 5/8/2020 12:00:00 AM Full Article
hear Drink Up! Coffee Won't Harm Your Heart, Study Finds By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Drink Up! Coffee Won't Harm Your Heart, Study FindsCategory: Health NewsCreated: 5/7/2020 12:00:00 AMLast Editorial Review: 5/8/2020 12:00:00 AM Full Article
hear COVID-19 Daily: Skin Manifestations, HCQ Heart Rhythm Risks By www.webmd.com Published On :: Wed, 06 May 2020 13:11:49 EST These are the coronavirus stories you need to know about today. Full Article
hear FDA Approves Diabetes Drug for Type of Heart Failure By www.webmd.com Published On :: Wed, 06 May 2020 14:03:53 EST The FDA today approved a new use for the diabetes drug, dapagliflozin (Farxiga), to reduce the risk of a hospital stay or death in people who have a type of heart failure. Full Article
hear Especially in the Young, Cholesterol Is No Friend to the Heart By www.medicinenet.com Published On :: Wed, 4 Dec 2019 00:00:00 PDT Title: Especially in the Young, Cholesterol Is No Friend to the HeartCategory: Health NewsCreated: 12/4/2019 12:00:00 AMLast Editorial Review: 12/4/2019 12:00:00 AM Full Article
hear AHA News: Statins May Do Double Duty on Heart Disease and Cancer By www.medicinenet.com Published On :: Tue, 7 Jan 2020 00:00:00 PDT Title: AHA News: Statins May Do Double Duty on Heart Disease and CancerCategory: Health NewsCreated: 1/6/2020 12:00:00 AMLast Editorial Review: 1/7/2020 12:00:00 AM Full Article
hear Intense Exercise Can Trigger Heart Trouble in the Unprepared By www.medicinenet.com Published On :: Tue, 3 Mar 2020 00:00:00 PDT Title: Intense Exercise Can Trigger Heart Trouble in the UnpreparedCategory: Health NewsCreated: 3/2/2020 12:00:00 AMLast Editorial Review: 3/3/2020 12:00:00 AM Full Article
hear Heart Attacks, Strokes Are Declining Among People With Diabetes By www.medicinenet.com Published On :: Mon, 4 May 2020 00:00:00 PDT Title: Heart Attacks, Strokes Are Declining Among People With DiabetesCategory: Health NewsCreated: 5/1/2020 12:00:00 AMLast Editorial Review: 5/4/2020 12:00:00 AM Full Article
hear Heart Drug Combos Might Also Lower Your Dementia Risk: Study By www.medicinenet.com Published On :: Mon, 16 Mar 2020 00:00:00 PDT Title: Heart Drug Combos Might Also Lower Your Dementia Risk: StudyCategory: Health NewsCreated: 3/13/2020 12:00:00 AMLast Editorial Review: 3/16/2020 12:00:00 AM Full Article
hear Rheumatoid Arthritis, Low Folate Levels Raise Heart Risks By www.medicinenet.com Published On :: Tue, 3 Mar 2020 00:00:00 PDT Title: Rheumatoid Arthritis, Low Folate Levels Raise Heart RisksCategory: Health NewsCreated: 3/2/2020 12:00:00 AMLast Editorial Review: 3/3/2020 12:00:00 AM Full Article
hear Your Best Bet Against Heart Attack, Stroke? Lower Blood Pressure By www.medicinenet.com Published On :: Fri, 21 Feb 2020 00:00:00 PDT Title: Your Best Bet Against Heart Attack, Stroke? Lower Blood PressureCategory: Health NewsCreated: 2/20/2020 12:00:00 AMLast Editorial Review: 2/21/2020 12:00:00 AM Full Article
hear Up Your Steps to Lower Blood Pressure, Heart Study Suggests By www.medicinenet.com Published On :: Fri, 27 Mar 2020 00:00:00 PDT Title: Up Your Steps to Lower Blood Pressure, Heart Study SuggestsCategory: Health NewsCreated: 3/26/2020 12:00:00 AMLast Editorial Review: 3/27/2020 12:00:00 AM Full Article
hear 'Couch Potato' Lifestyle Poses Danger to Women's Hearts By www.medicinenet.com Published On :: Wed, 19 Feb 2020 00:00:00 PDT Title: 'Couch Potato' Lifestyle Poses Danger to Women's HeartsCategory: Health NewsCreated: 2/18/2020 12:00:00 AMLast Editorial Review: 2/19/2020 12:00:00 AM Full Article
hear More Hot Flashes Could Mean Higher Odds for Heart Trouble By www.medicinenet.com Published On :: Tue, 24 Sep 2019 00:00:00 PDT Title: More Hot Flashes Could Mean Higher Odds for Heart TroubleCategory: Health NewsCreated: 9/24/2019 12:00:00 AMLast Editorial Review: 9/24/2019 12:00:00 AM Full Article
hear How Does Early Menopause Affect a Woman's Heart? By www.medicinenet.com Published On :: Fri, 11 Oct 2019 00:00:00 PDT Title: How Does Early Menopause Affect a Woman's Heart?Category: Health NewsCreated: 10/10/2019 12:00:00 AMLast Editorial Review: 10/11/2019 12:00:00 AM Full Article
hear Untreated Sleep Apnea Puts Your Heart at High Risk By www.medicinenet.com Published On :: Tue, 4 Feb 2020 00:00:00 PDT Title: Untreated Sleep Apnea Puts Your Heart at High RiskCategory: Health NewsCreated: 2/3/2020 12:00:00 AMLast Editorial Review: 2/4/2020 12:00:00 AM Full Article
hear Erratic Sleep Habits May Boost Risk of Heart Problems: Study By www.medicinenet.com Published On :: Thu, 5 Mar 2020 00:00:00 PDT Title: Erratic Sleep Habits May Boost Risk of Heart Problems: StudyCategory: Health NewsCreated: 3/4/2020 12:00:00 AMLast Editorial Review: 3/5/2020 12:00:00 AM Full Article
hear A Consistent Bedtime Is Good for Your Heart By www.medicinenet.com Published On :: Mon, 6 Apr 2020 00:00:00 PDT Title: A Consistent Bedtime Is Good for Your HeartCategory: Health NewsCreated: 4/3/2020 12:00:00 AMLast Editorial Review: 4/6/2020 12:00:00 AM Full Article
hear Cerebellar ataxia, neuropathy, hearing loss, and intellectual disability due to AIFM1 mutation By ng.neurology.org Published On :: 2020-04-09T12:45:11-07:00 Objective To describe the clinical and molecular genetic findings in a family segregating a novel mutation in the AIFM1 gene on the X chromosome. Methods We studied the clinical features and performed brain MRI scans, nerve conduction studies, audiometry, cognitive testing, and clinical exome sequencing (CES) in the proband, his mother, and maternal uncle. We used in silico tools, X chromosome inactivation assessment, and Western blot analysis to predict the consequences of an AIFM1 variant identified by CES and demonstrate its pathogenicity. Results The proband and his maternal uncle presented with childhood-onset nonprogressive cerebellar ataxia, hearing loss, intellectual disability (ID), peripheral neuropathy, and mood and behavioral disorder. The proband's mother had mild cerebellar ataxia, ID, and mood and behavior disorder, but no neuropathy or hearing loss. The 3 subjects shared a variant (c.1195G>A; p.Gly399Ser) in exon 12 of the AIFM1 gene, which is not reported in the exome/genome sequence databases, affecting a critical amino acid for protein function involved in NAD(H) binding and predicted to be pathogenic with very high probability by variant analysis programs. X chromosome inactivation was highly skewed in the proband's mother. The mutation did not cause quantitative changes in protein abundance. Conclusions Our report extends the molecular and phenotypic spectrum of AIFM1 mutations. Specific findings include limited progression of neurologic abnormalities after the first decade and the coexistence of mood and behavior disorder. This family also shows the confounding effect on the phenotype of nongenetic factors, such as alcohol and drug use and side effects of medication. Full Article
hear Rupture geometries in anisotropic amphibolite recorded by pseudotachylytes in the Gairloch Shear Zone, NW Scotland By sjg.lyellcollection.org Published On :: 2019-11-29T02:21:48-08:00 Recent earthquakes involving complex multi-fault rupture have increased our appreciation of the variety of rupture geometries and fault interactions that occur within the short duration of coseismic slip. Geometrical complexities are intrinsically linked with spatially heterogeneous slip and stress drop distributions, and hence need incorporating into seismic hazard analysis. Studies of exhumed ancient fault zones facilitate investigation of rupture processes in the context of lithology and structure at seismogenic depths. In the Gairloch Shear Zone, NW Scotland, foliated amphibolites host pseudotachylytes that record rupture geometries of ancient low-magnitude (≤MW 3) seismicity. Pseudotachylyte faults are commonly foliation parallel, indicating exploitation of foliation planes as weak interfaces for seismic rupture. Discordance and complexity are introduced by fault segmentation, stepovers, branching and brecciated dilational volumes. Pseudotachylyte geometries indicate that slip nucleation initiated simultaneously across several parallel foliation planes with millimetre and centimetre separations, leading to progressive interaction and ultimately linkage of adjacent segments and branches within a single earthquake. Interacting with this structural control, a lithological influence of abundant low disequilibrium melting-point amphibole facilitated coseismic melting, with relatively high coseismic melt pressure encouraging transient dilational sites. These faults elucidate controls and processes that may upscale to large active fault zones hosting major earthquake activity. Supplementary material: Supplementary Figures 1 and 2, unannotated versions of field photographs displayed in Figures 4a and 5 respectively, are available at https://doi.org/10.6084/m9.figshare.c.4573256 Thematic collection: This article is part of the SJG Collection on Early-Career Research available at: https://www.lyellcollection.org/cc/SJG-early-career-research Full Article
hear A rapid intrinsic heart rate resetting response with thermal acclimation in rainbow trout, Oncorhynchus mykiss [RESEARCH ARTICLE] By jeb.biologists.org Published On :: 2020-04-27T23:57:20-07:00 Rachel L. Sutcliffe, Shaorong Li, Matthew J. H. Gilbert, Patricia M. Schulte, Kristi M. Miller, and Anthony P. FarrellWe examined cardiac pacemaker rate resetting in rainbow trout following a reciprocal temperature transfer. In the original experiment, performed in winter, 4°C-acclimated fish transferred to 12°C reset intrinsic heart rate after just 1 h (from 56.8±1.2 to 50.8±1.5 bpm); 12°C-acclimated fish transferred to 4°C reset intrinsic heart rate after 8 h (from 33.4±0.7 to 37.7±1.2 bpm). However, in a replicate experiment, performed in the summer using a different brood year, intrinsic heart rate was not reset, even after 10 weeks at a new temperature. Using this serendipitous opportunity, we compared mRNA expression changes of a suite of proteins in sinoatrial node (SAN), atrial and ventricular tissues after both 1 h and longer than 3 weeks for both experimental acclimation groups to identify those changes only associated with pacemaker rate resetting. Of the changes in mRNA expression occurring after more than 3 weeks of warm acclimation and associated with pacemaker rate resetting, we observed downregulation of NKA α1c in the atrium and ventricle, and upregulation of HCN1 in the ventricle. However, in the SAN there were no mRNA expression changes unique to the fish with pacemaker rate resetting after either 1 h or 3 weeks of warm acclimation. Thus, despite identifying changes in mRNA expression of contractile cardiac tissues, there was absence of changes in mRNA expression directly involved with the initial, rapid pacemaker rate resetting with warm acclimation. Importantly, pacemaker rate resetting with thermal acclimation does not always occur in rainbow trout. Full Article
hear The shear stiffness criterion for rock joints considering rock wear behaviour By qjegh.lyellcollection.org Published On :: 2020-05-01T00:46:18-07:00 Rock is a material that is affected by wear, and the curvature of the asperities on a rock joint surface increases with the degree of wear after shearing. Based on the Greenwood and Williamson (GW) model, a new model considering the change of asperity curvature is proposed to explain the wear behaviour of rock joints. First, the shear stiffness formula for a joint surface is derived when the asperity curvature is constant, which shows that the shear stiffness increases with increase of asperity curvature. According to the Mohr–Coulomb criterion, the yield position of a single asperity under normal force and tangential friction force is discussed. Then, the critical normal force for a single asperity at a specific friction coefficient is obtained, which shows that the normal force corresponds to the curvature radius of the asperity. A rough surface model with multi-level curvature radius is proposed. With increase of normal force, the higher-order asperities gradually fail and the curvature radius become larger. A specific pressure value excites a specific radius of curvature, and the larger the pressure, the larger the radius of curvature. The relation between the normal force and the curvature radius is proposed and a shear stiffness formula considering the change of curvature radius of the asperity is derived. The proposed model is verified on the basis of the published experimental results. The calculation results of the proposed model can reflect the test results well: for a given joint surface, with increase in normal force the joint surface gradually becomes smooth; for different joint surfaces, with increase in roughness, the joint surface is more easily smoothed. Full Article
hear Both Prediabetes and Type 2 Diabetes Are Associated With Lower Heart Rate Variability: The Maastricht Study By care.diabetesjournals.org Published On :: 2020-04-20T12:00:33-07:00 OBJECTIVE Low heart rate variability (HRV), a marker for cardiac autonomic dysfunction, is a known feature of type 2 diabetes, but it remains incompletely understood whether this also applies to prediabetes or across the whole glycemic spectrum. Therefore, we investigated the association among prediabetes, type 2 diabetes, and measures of glycemia and HRV. RESEARCH DESIGN AND METHODS In the population-based Maastricht Study (n = 2,107; mean ± SD age 59 ± 8 years; 52% men; normal glucose metabolism [n = 1,226], prediabetes [n = 331], and type 2 diabetes [n = 550, oversampled]), we determined 24-h electrocardiogram-derived HRV in time and frequency domains (individual z-scores, based upon seven and six variables, respectively). We used linear regression with adjustments for age, sex, and major cardiovascular risk factors. RESULTS After adjustments, both time and frequency domain HRV were lower in prediabetes and type 2 diabetes as compared with normal glucose metabolism (standardized β [95% CI] for time domain: –0.15 [–0.27; –0.03] and –0.34 [–0.46; –0.22], respectively, P for trend <0.001; for frequency domain: –0.14 [–0.26; –0.02] and –0.31 [–0.43; –0.19], respectively, P for trend <0.001). In addition, 1-SD higher glycated hemoglobin, fasting plasma glucose, and 2-h postload glucose were associated with lower HRV in both domains (time domain: –0.16 [–0.21; –0.12], –0.16 [–0.21; –0.12], and –0.15 [–0.20; –0.10], respectively; frequency domain: –0.14 [–0.19; –0.10], –0.14 [–0.18; –0.09], and –0.13 [–0.18; –0.08], respectively). CONCLUSIONS Both prediabetes and type 2 diabetes were independently associated with lower HRV. This is further substantiated by independent continuous associations between measures of hyperglycemia and lower HRV. These data strongly suggest that cardiac autonomic dysfunction is already present in prediabetes. Full Article
hear Dalcetrapib Reduces Risk of New-Onset Diabetes in Patients With Coronary Heart Disease By care.diabetesjournals.org Published On :: 2020-04-20T12:00:33-07:00 OBJECTIVE Incident type 2 diabetes is common among patients with recent acute coronary syndrome and is associated with an adverse prognosis. Some data suggest that cholesteryl ester transfer protein (CETP) inhibitors reduce incident type 2 diabetes. We compared the effect of treatment with the CETP inhibitor dalcetrapib or placebo on incident diabetes in patients with recent acute coronary syndrome. RESEARCH DESIGN AND METHODS In the dal-OUTCOMES trial, 15,871 patients were randomly assigned to treatment with dalcetrapib 600 mg daily or placebo, beginning 4–12 weeks after an acute coronary syndrome. Absence of diabetes at baseline was based on medical history, no use of antihyperglycemic medication, and hemoglobin A1c and serum glucose levels below diagnostic thresholds. Among these patients, incident diabetes after randomization was defined by any diabetes-related adverse event, new use of antihyperglycemic medication, hemoglobin A1c ≥6.5%, or a combination of at least two measurements of serum glucose ≥7.0 mmol/L (fasting) or ≥11.1 mmol/L (random). RESULTS At baseline, 10,645 patients (67% of the trial cohort) did not have diabetes. During a median follow-up of 30 months, incident diabetes was identified in 403 of 5,326 patients (7.6%) assigned to dalcetrapib and in 516 of 5,319 (9.7%) assigned to placebo, corresponding to absolute risk reduction of 2.1%, hazard ratio of 0.77 (95% CI 0.68–0.88; P < 0.001), and a need to treat 40 patients for 3 years to prevent 1 incident case of diabetes. Considering only those with prediabetes at baseline, the number needed to treat for 3 years to prevent 1 incident case of diabetes was 25. Dalcetrapib also decreased the number of patients who progressed from normoglycemia to prediabetes and increased the number who regressed from diabetes to no diabetes. CONCLUSIONS In patients with a recent acute coronary syndrome, incident diabetes is common and is reduced substantially by treatment with dalcetrapib. Full Article
hear A broken heart is a door open for others By bjgp.org Published On :: 2020-04-30T16:04:41-07:00 Full Article
hear As the profession soldiers on, all members hear the call to arms By bjgp.org Published On :: 2020-04-30T16:04:41-07:00 Full Article
hear Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects By www.basictranslational.onlinejacc.org Published On :: 2020-04-27T11:00:20-07:00 Genetic variants are the primary driver of congenital heart disease (CHD) pathogenesis. However, our ability to identify causative variants is limited. To identify causal CHD genes that are associated with specific molecular functions, the study used prior knowledge to filter de novo variants from 2,881 probands with sporadic severe CHD. This approach enabled the authors to identify an association between left ventricular outflow tract obstruction lesions and genes associated with the WAVE2 complex and regulation of small GTPase-mediated signal transduction. Using CRISPR zebrafish knockdowns, the study confirmed that WAVE2 complex proteins brk1, nckap1, and wasf2 and the regulators of small GTPase signaling cul3a and racgap1 are critical to cardiac development. Full Article
hear In Situ Immune Profiling of Heart Transplant Biopsies Improves Diagnostic Accuracy and Rejection Risk Stratification By www.basictranslational.onlinejacc.org Published On :: 2020-04-27T11:00:20-07:00 Recognizing that guideline-directed histologic grading of endomyocardial biopsy tissue samples for rejection surveillance has limited diagnostic accuracy, quantitative, in situ characterization was performed of several important immune cell types in a retrospective cohort of clinical endomyocardial tissue samples. Differences between cases were identified and were grouped by histologic grade versus clinical rejection trajectory, with significantly increased programmed death ligand 1+, forkhead box P3+, and cluster of differentiation 68+ cells suppressed in clinically evident rejections, especially cases with marked clinical-histologic discordance. Programmed death ligand 1+, forkhead box P3+, and cluster of differentiation 68+ cell proportions are also significantly higher in "never-rejection" when compared with "future-rejection." These findings suggest that in situ immune modulators regulate the severity of cardiac allograft rejection. Full Article
hear Design of the {beta}3-Adrenergic Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure Trial By www.basictranslational.onlinejacc.org Published On :: 2020-04-27T11:00:20-07:00 Combined pre-and post-capillary hypertension (CpcPH) is a relatively common complication of heart failure (HF) associated with a poor prognosis. Currently, there is no specific therapy approved for this entity. Recently, treatment with beta-3 adrenergic receptor (β3AR) agonists was able to improve pulmonary hemodynamics and right ventricular (RV) performance in a translational, large animal model of chronic PH. The authors present the design of a phase II randomized clinical trial that tests the benefits of mirabegron (a clinically available β3AR agonist) in patients with CpcPH due to HF. The effect of β3AR treatment will be evaluated on pulmonary hemodynamics, as well as clinical, biochemical, and advanced cardiac imaging parameters. (Beta3 Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure [SPHERE-HF]; NCT02775539) Full Article
hear [Developmental Biology] Reptiles as a Model System to Study Heart Development By cshperspectives.cshlp.org Published On :: 2020-05-01T06:30:17-07:00 A chambered heart is common to all vertebrates, but reptiles show unparalleled variation in ventricular septation, ranging from almost absent in tuataras to full in crocodilians. Because mammals and birds evolved independently from reptile lineages, studies on reptile development may yield insight into the evolution and development of the full ventricular septum. Compared with reptiles, mammals and birds have evolved several other adaptations, including compact chamber walls and a specialized conduction system. These adaptations appear to have evolved from precursor structures that can be studied in present-day reptiles. The increase in the number of studies on reptile heart development has been greatly facilitated by sequencing of several genomes and the availability of good staging systems. Here, we place reptiles in their phylogenetic context with a focus on features that are primitive when compared with the homologous features of mammals. Further, an outline of major developmental events is given, and variation between reptile species is discussed. Full Article
hear DO YOU WANT TO OWN AN APARTMENT IN THE HEART OF QUY NHON CITY? By batdongsan.com.vn Published On :: Thu, 16 Apr 2020 16:14:00 GMT DO YOU WANT TO OWN AN APARTMENT IN THE HEART OF QUY NHON CITY? - Unique and prime location, at 1 Nguyen Tat Thanh, the arterial road of Quy Nhon city, 4 facades 3 frontal face sea. - The project belongs to the segment of luxury apartments, 5-star utilities, strategic location in ... Full Article
hear Room for rent in the heart of HCMC By batdongsan.com.vn Published On :: Wed, 20 Nov 2019 16:35:00 GMT Location: Backpacker area- Bui Vien walking street Facilities: Queen bed, private toilet and bathroom, private kitchen and washing machine, ... Other facilities: Elevator, rooftop sitting area, living room. Price: 7 million VND/month. Electricity: 4.000 vnd/kw. water: 200.000 vnd... Full Article
hear River view apartment, located right in the heart of Saigon, Suitable for foreigners - Picity Hight By batdongsan.com.vn Published On :: Thu, 07 May 2020 16:37:00 GMT PiCity High Park Thanh Xuan - District 12 - Apartments worth living.- Price from only 1.5 billion / unit too attractive to invest or settle down.- The golden position is only 20 minutes from Tan Son Nhat airport.- Separate pink book, MB Bank loan support 70% for 20 years.- 4 star... Full Article
hear RIVERSIDE VILLA A RARE COMMODITY IN THE HEART OF SAIGON SAIGON GARDEN RIVERSIDE VILLAGE By batdongsan.com.vn Published On :: Mon, 04 May 2020 16:41:00 GMT Project overview: -Location: Long Phuoc ward, district 9, Ho Chi Minh city. -Investor: Sai Gon Garden Resort Property Joint Stock Company. -Scale: 30 ha. -Total lots: 168 lots. -Area: From 1.000 m2/lot. -Type: Garden villa. -Private pool for each villa. -Project legal: Pink book ... Full Article
hear Telco You've Never Heard Of Is Flogging 103GB Data For $38 A Month With No Contract By feeds.gizmodo.com.au Published On :: Tue, 05 May 2020 11:45:34 +1000 Circles.Life is a little-known telco with a questionable name choice. But it also happens to have a real hectic SIM-only plan deal right now. For $38 a month you get a whopping 103GB data -- also per month. And you don't even need to sign a contract. More » Full Article
hear Pluto's icy nitrogen heart makes its atmosphere spin backwards By www.newscientist.com Published On :: Wed, 05 Feb 2020 21:43:26 +0000 Every day on Pluto, nitrogen puffs out the icy world’s heart-shaped plain into the atmosphere, and every night it refreezes, creating winds unlike any we’ve seen before Full Article
hear Monster rocky exoplanet could let us glimpse the heart of Jupiter By www.newscientist.com Published On :: Thu, 09 Apr 2020 12:00:28 +0000 An enormous rocky planet orbiting a distant star may be a gas giant that has had its atmosphere ripped off, which could help us understand how huge worlds like Jupiter form Full Article
