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Pragmatic vs Explanatory Trials

To the Editor We read with interest the study by Sepehrvand et al, which described secular trends in the conduct of pragmatic or explanatory cardiovascular randomized clinical trials over 2 decades. We believe extension of this thoughtful analysis can provide additional insights into pragmatic vs explanatory trials.




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Pragmatic vs Explanatory Trials—Reply

In Reply We thank Fernandes et al for their interest in our study and agree that this field requires further exploration. Explanatory trials are primed to maximize the likelihood of finding efficacy of an intervention by testing it in an ideal setting, whereas pragmatic trials aim to test effectiveness of an intervention in a more generalizable setting. Hence, they are expected to generate more generalizable results, with the risk understood that there may be more variation in less tightly controlled environments, which may result in differing results.




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Microfabrication for industrial applications / Regina Luttge

Luttge, Regina




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T'gana to audit 36 units using industrial gases

Authorities in Telangana have identified 36 units dealing with industrial gases and will carry out an audit of these industries considering the gas leak at LG Polymers in Visakhapatnam.




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ESI hospital gets nod for Covid-19 plasma trials

ESI Hospital at Sanathnagar have received permission to carry out plasma therapy trials for Covid- 19 patients along with the state-run Gandhi Hospital. ICMR officially accorded permission to both hospitals for six months.




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Essential Oil Research: Trends in Biosynthesis, Analytics, Industrial Applications and Biotechnological Production / Sonia Malik, editor

Online Resource




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Industrial biotechnology / Mark Anthony Benvenuto

Hayden Library - TP248.2.B46 2019




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Jesus Caesar : a Roman reading of the Johannine trial narrative / Laura J. Hunt

Hunt, Laura J., author




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Industrial Microbiology


 
Focusing on current and future uses of microbes as production organisms, this practice-oriented textbook complements traditional texts on microbiology and biotechnology.
The editors have brought together leading researchers and professionals from the entire field of industrial microbiology and together they adopt a modern approach to a well-known subject. Following a brief introduction to the technology of microbial processes, the twelve most important

Read More...






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JAMA Neurology : Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke

Interview with Adrian F. Hernandez, MD, MHS, author of Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke: Findings From the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study






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Sensational murder trial of Shrien Dewani under international scrutiny



  • DO NOT USE Indians Abroad
  • World

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Indian-origin ex-lawmaker in Germany stands trial for child pornography



  • DO NOT USE Indians Abroad
  • World

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Frustrated with lawyers, techie seeks execution over trial



  • DO NOT USE Indians Abroad
  • World

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Indian-origin researcher helps in Ebola vaccine trials



  • DO NOT USE Indians Abroad
  • World

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Do exclusionary rules ensure a fair trial?: a comparative perspective on evidentiary rules / Sabine Gless, Thomas Richter, editors

Online Resource




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Selma and the Liuzzo murder trials: the first modern civil rights convictions / by James P. Turner

Dewey Library - KF224.K7 T87 2018




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Punishing atrocities through a fair trial: international criminal law from Nuremberg to the age of global terrorism / Jonathan Hafetz

Dewey Library - KZ7050.H34 2018




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The U.S. Supreme Court and racial minorities: two centuries of judicial review on trial / Leslie F. Goldstein, Judge Hugh M. Moris Professor Emerita, University of Delaware, USA

Dewey Library - KF8742.G65 2017




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Industrial Placement - Defence Security Analysis Division: Defence Science and Technology Laboratory

£Attractive: Defence Science and Technology Laboratory
For more latest jobs and jobs in South West England visit brightrecruits.com



  • South West England

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Industrial Placement - Counter Terrorism and Security Division: Defence Science and Technology Laboratory

£Attractive: Defence Science and Technology Laboratory
For more latest jobs and jobs in South West England visit brightrecruits.com



  • South West England

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Employment and re-industrialisation in post Soeharto Indonesia / Mohammad Zulfan Tadjoeddin, Anis Chowdhury

Tadjoeddin, Mohammad Zulfan, author




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A reckoning : Philippine trials of Japanese war criminals / Sharon W. Chamberlain

Chamberlain, Sharon W., author




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Bailey's Industrial Oil and Fat Products, 7 Volume Set, 7th Edition


 

The new seventh edition of the industry bible of oils and fats processing, extensively revised, expanded, and updated.

Bailey's Industrial Oil and Fat Products is the definitive reference source on the food chemistry and processing technology of edible oils and oil-derived nonedible byproducts. Spanning seven themed volumes, this comprehensive work features contributions from more than 100 internationally recognized experts in their respective fields



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Arkema to go on trial for Crosby fires

The chemical maker intends to argue that the fires should be considered an act of God




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Lilly and Roche antiamyloid drugs fail in trial of early-onset Alzheimer's trial




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Emory-discovered antiviral is poised for COVID-19 clinical trials

The nucleoside inhibitor has advantages over Gilead's remdesivir but has yet to be tested in humans




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COVID-19 to delay clinical trials

Drugmakers want to keep trials going but acknowledge that medical resources are strained




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Clinical trial for ruxolitinib planned in fight against COVID-19

Treatment for rare blood cancers could temper cytokine storm in people with severe forms of the disease




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Clinical trial for ruxolitinib planned in fight against COVID-19

Treatment for rare blood cancers could temper cytokine storm in people with severe forms of the disease




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COVID-19 vaccines are moving toward clinical trials

Tests of 10 or more novel vaccines could be underway by mid-May




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How industrial gas firms are meeting demand for medical oxygen for COVID-19 patients

COVID-19 is driving a fivefold or greater increase in demand




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Clinical trials planned to put hydroxychloroquine to the test for COVID-19

The antimalaria drug will be tested for treating or preventing the disease in thousands of people worldwide




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Does the FDA's authorization for chloroquine impede clinical trials for COVID-19 drugs?

Despite the hype, support for the use of chloroquine and its relative hydroxychloroquine outside a clinical trial remains mixed




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ACS honors 4 industrial teams with its 2020 Heroes of Chemistry award

Innovations have led to advances in cataract surgery, water purification, semiconductor fabrication, and tuberculosis drugs




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Stable immobilized amine sorbents for heavy metal and REE removal from industrial wastewaters

Environ. Sci.: Water Res. Technol., 2020, 6,1286-1299
DOI: 10.1039/C9EW00915A, Paper
Walter Christopher Wilfong, Brian W. Kail, Qiuming Wang, Fan Shi, Greg Shipley, Thomas J. Tarka, McMahan L. Gray
Stable and immobilized amine sorbents can simultaneously remove/recover cationic and oxyanionic toxic metals plus valuable rare earth elements from industrial and mining effluents prior to discharging into environmental water systems.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Transformation of Sydney's industrial historic waterfront: the production of tourism for consumption / Ece Kaya

Online Resource




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Biography of an industrial landscape: Carlsberg's urban spaces retold / Svava Riesto

Rotch Library - HT169.D42 C685 2018




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[ASAP] Cost-Effective and Sustainable Preparation of Porous Mullite-Based Ceramics Combining MoO<sub>3</sub> Recovery from Industrial Calcine

ACS Sustainable Chemistry & Engineering
DOI: 10.1021/acssuschemeng.0c00079




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Industrial enzymes : structure, function and applications / edited by Julio Polaina and Andrew P. MacCabe




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Manual of industrial microbiology and biotechnology / editors in chief, Richard H. Baltz, Julian E. Davies, Arnold L. Demain ; editors, Alan T. Bull ... [et al.]




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The effect of culinary doses of spices in a high-saturated fat, high-carbohydrate meal on postprandial lipemia and endothelial function: a randomized, controlled, crossover pilot trial

Food Funct., 2020, 11,3191-3200
DOI: 10.1039/C9FO02438G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kristina S. Petersen, Connie J. Rogers, Sheila G. West, David N. Proctor, Penny M. Kris-Etherton
Lower doses of spices (2 and 6 g) than previously tested may attenuate postprandial lipemia and impairments in endothelial function caused by a high-saturated fat, high-carbohydrate meal.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Efficacy of proprietary Lactobacillus casei for anti-tuberculosis associated gastrointestinal adverse reactions in adult patients: a randomized, open-label, dose–response trial

Food Funct., 2020, 11,3751-3751
DOI: 10.1039/D0FO90017F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Song Lin, Shanliang Zhao, Jiahong Liu, Jianwen Zhang, Chao Zhang, Haibo Hao, Yuxia Sun, Jing Cai, Yang Yang, Yan Ma, Yuanyuan Li, Jinyu Wang, Aiguo Ma
The content of this RSS Feed (c) The Royal Society of Chemistry




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Adjunctive vitamin A and D during pulmonary tuberculosis treatment: a randomized controlled trial with a 2×2 factorial design

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02751C, Paper
Jinyu Wang, Ke Xiong, Qiuzhen Wang, Shanliang Zhao, Yufeng Liu, Aiguo Ma
Background and objective: Vitamin A and D have immunoregulatory effects and may improve the response to pulmonary tuberculosis treatment. The interaction of vitamin A and D on pulmonary tuberculosis treatment...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hyderabad: ESI hospital gets nod for Covid-19 plasma trials

Hyderabad: ESI hospital gets nod for Covid-19 plasma trials




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Coronavirus | Phase-2 trial with three drugs offers hope

Testing in Hong Kong hospitals shows the regimen clears coronavirus in 7 days in the mildly ill.




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Effect of a Dietary Portfolio of Cholesterol-Lowering Foods Given at 2 Levels of Intensity of Dietary Advice on Serum Lipids in Hyperlipidemia: A Randomized Controlled Trial

Interview with David J. A. Jenkins, MD, author of Effect of a Dietary Portfolio of Cholesterol-Lowering Foods Given at 2 Levels of Intensity of Dietary Advice on Serum Lipids in Hyperlipidemia: A Randomized Controlled Trial