Interview with Eric J. Topol, MD, author of Bridging Antiplatelet Therapy With Cangrelor in Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial

Interview with Soeren Mattke, MD, DSc, author of Utilization of Anesthesia Services During Outpatient Endoscopies and Colonoscopies and Associated Spending in 2003-2009

Interview with Ferran Barbé, MD, author of Effect of Continuous Positive Airway Pressure on the Incidence of Hypertension and Cardiovascular Events in Nonsleepy Patients With Obstructive Sleep Apnea: A Randomized Controlled Trial

Interview with David C. Mohr, PhD, author of Effect of Telephone-Administered vs Face-to-face Cognitive Behavioral Therapy on Adherence to Therapy and Depression Outcomes Among Primary Care Patients: A Randomized Trial

Interview with Rebecca Smith-Bindman, MD, author of Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010

Interview with Jeffrey R. Curtis, MD, MS, author of Association Between Vaccination for Herpes Zoster and Risk of Herpes Zoster Infection Among Older Patients With Selected Immune-Mediated Diseases: Herpes Zoster and Immune-Mediated Diseases

Interview with Helen Tremlett, PhD, author of Association Between Use of Interferon Beta and Progression of Disability in Patients With Relapsing-Remitting Multiple Sclerosis

Interview with James A. Blumenthal, PhD, author of Effects of Exercise Training on Depressive Symptoms in Patients With Chronic Heart Failure: The HF-ACTION Randomized Trial

Interview with Stephan Windecker, MD, author of Effect of Biolimus-Eluting Stents With Biodegradable Polymer vs Bare-Metal Stents on Cardiovascular Events Among Patients With Acute Myocardial Infarction: The COMFORTABLE AMI Randomized Trial

Interview with Maria E Suarez-Almazor, MD, PhD, author of Risk of Malignancies in Patients with Rheumatoid Arthritis Treated with Biologic Therapy: A Meta-analysis

Interview with Matthew K. Wynia, MD, MPH, author of Challenges at the Intersection of Team-Based and Patient-Centered Health Care: Insights From an IOM Working Group

Interview with Ted E. Palen, MD, PhD, MSPH, author of Association of Online Patient Access to Clinicians and Medical Records With Use of Clinical Services

Interview with Sangeeta Mehta, MD, author of Daily Sedation Interruption in Mechanically Ventilated Critically Ill Patients Cared for With a Sedation Protocol

Interview with Gilles Montalescot, MD, PhD, author of Association of Clopidogrel Pretreatment With Mortality, Cardiovascular Events, and Major Bleeding Among Patients Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis

Interview with Timothy McAlindon, DM, MPH, author of Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume Loss in Patients With Symptomatic Osteoarthritis: A Randomized Controlled Trial

Interview with Gervasio A. Lamas, MD, author of Effect of Disodium EDTA Chelation Regimen on Cardiovascular Events in Patients With Previous Myocardial Infarction: The TACT Randomized Trial

Interview with Ellen M. Lavoie Smith, PhD, author of Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy: A Randomized Clinical Trial

Interview with Jeffrey S. Gerber, MD, PhD, author of Effect of an Outpatient Antimicrobial Stewardship Intervention on Broad-Spectrum Antibiotic Prescribing by Primary Care Pediatricians: A Randomized Trial

Interview with Edna B. Foa, PhD, author of Concurrent Naltrexone and Prolonged Exposure Therapy for Patients With Comorbid Alcohol Dependence and PTSD: A Randomized Clinical Trial

Interview with Anthony S. Fauci, MD, author of Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial

Interview with Simon Thom, MB,BS, MD, author of Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD: The UMPIRE Randomized Clinical Trial

Interview with Cynthia J. Brown, MD, author of Mobility Limitation in the Older Patient: A Clinical Review

Interview with Christian Torp-Pedersen, MD, DSc, author of Association of National Initiatives to Improve Cardiac Arrest Management With Rates of Bystander Intervention and Patient Survival After Out-of-Hospital Cardiac Arrest

Interview with Jacob A. Udell, MD, MPH, FRCPC, author of Association Between Influenza Vaccination and Cardiovascular Outcomes in High-Risk Patients: A Meta-analysis

Interview with Prashanthan Sanders, MBBS, PhD, author of Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial

Interview with J. Randall Curtis, MD, MPH, author of Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial

Interview with Juan Jesús Carrero, PhD(Pharm and Med), author of Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation

Interview with Derek C. Angus, MD, MPH, author of Psychiatric Diagnoses and Psychoactive Medication Use Among Nonsurgical Critically Ill Patients Receiving Mechanical Ventilation

Interview with Mohamed Abdel-Wahab, MD, author of Comparison of Balloon-Expandable vs Self-expandable Valves in Patients Undergoing Transcatheter Aortic Valve Replacement: The CHOICE Randomized Clinical Trial

Interview with Kim L. Bennell, PhD, author of Effect of Physical Therapy on Pain and Function in Patients With Hip Osteoarthritis: A Randomized Clinical Trial

Interview with Eric M. Mortensen, MD, MSc, author of Association of Azithromycin With Mortality and Cardiovascular Events Among Older Patients Hospitalized With Pneumonia

Interview with Christianne L. Roumie, MD, MPH, author of Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes

Interview with Nynne Nyboe Andersen, MD, author of Association Between Tumor Necrosis Factor-α Antagonists and Risk of Cancer in Patients With Inflammatory Bowel Disease

Interview with Mark S. Sulkowski, MD, author of Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection

Interview with Irfan A. Dhalla, MD, MSc, author of Effect of a Postdischarge Virtual Ward on Readmission or Death for High-Risk Patients

Interview with George A. Stouffer, MD, author of Association of Inpatient vs Outpatient Onset of ST-Elevation Myocardial Infarction With Treatment and Clinical Outcomes

Interview with Joseph B. Muhlestein, MD, author of Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes

Interview with Mitesh S. Patel, MD, MBA, MS, author of Association of the 2011 ACGME Resident Duty Hour Reforms With Mortality and Readmissions Among Hospitalized Medicare Patients

Interview with Tracy Y. Wang, MD, MHS, MSc, author of Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction

Interview with Jeffrey L. Cummings, MD, ScD, author of Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial

ACS is a common and potentially lethal problem. However, only about 10% of patients who present to an emergency department with chest pain actually have ACS. In this JAMA Clinical Reviews podcast, we discuss which signs, symptoms and tests used to make the diagnosis of ACS are reliable.

Edward H. Livingston MD, speaks with Alexander Fanaroff, MD, author of Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review as well as a patient who was diagnosed with myocardial infarction.

Edward H. Livingston, MD, Deputy Editor of Clinical Reviews and Education and Jon Tilburt, MD, from the Mayo Clinic explain prostate cancer screening. For more information, read the JAMA Patient Page on this topic.

Interview with Roger Stupp, MD, author of Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial

Interview with Dalane W. Kitzman, MD, author of Effect of Caloric Restriction or Aerobic Exercise Training on Peak Oxygen Consumption and Quality of Life in Obese Older Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial

Interview with Gaëtan Deslée, MD, PhD, author of Lung Volume Reduction Coil Treatment vs Usual Care in Patients With Severe Emphysema: The REVOLENS Randomized Clinical Trial

Interview with Douglas B. White, MD, MAS, author of Prevalence of and Factors Related to Discordance About Prognosis Between Physicians and Surrogate Decision Makers of Critically Ill Patients

Drs Stuart Spechler and Peter Kahrilis discuss GERD and esophagitis--how they occur and how they are treated. Dr Spechler also discusses a new hypothesis regarding how reflux esophagitis is caused that differs from the traditional teaching that acid and pepsin reflux into the esophagus and burn the mucosa layers.

Related articles:
Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes
Turning the Pathogenesis of Acute Peptic Esophagitis Inside Out

When managing septic shock, passive leg raising is the best test to determine if a patient is likely to respond to a fluid bolus, better than CVP lines or even bedside ultrasound. Dr Najib Ayas, Associate professor of Critical Care Medicine at the University of British Columbia, discusses shock management from the context of his Rational Clinical examination article in the September 27, 2016 issue of JAMA, entitled “Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?”

Workplace violence–related injuries occur disproportionately in health care settings. In this podcast, we discuss how individual clinicians should manage violent patients who might attack them. Article discussed in this episode: Ensuring Staff Safety When Treating Potentially Violent Patients

Interview with Freddie C. Hamdy, MD, FRCSEd(Urol), and Jenny L Donovan, PhD, FMedSci, authors of Patient-Reported Outcomes Following Treatment for Localized Prostate Cancer: Helping Decision Making for Patients and Their Physicians