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Long-term delivery of alendronate through an injectable tetra-PEG hydrogel to promote osteoporosis therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00376J, Paper
Dawei Li, Jin Zhou, Mingming Zhang, Yuanzheng Ma, Yanyu Yang, Xue Han, Xing Wang
An alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy and bone regeneration.
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Core–shell particles for drug-delivery, bioimaging, sensing, and tissue engineering

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01872G, Review Article
Ratchapol Jenjob, Treethip Phakkeeree, Daniel Crespy
Core–shell particles offer significant advantages in their use for bioimaging and biosensors.
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A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00204F, Paper
Yongju He, Linjie Shao, Ibrahim Usman, Yao Hu, Anqiang Pan, Shuquan Liang, Hui Xu
The dilemma between tumor accumulation and renal clearance has severely limited the efficacy of mesoporous silica-based drug nanocarrier in cancer therapy. Herein, a pH-responsive dissociable mesoporous silica-based nanoplatform with efficient...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Trastuzumab targeted micellar delivery of docetaxel using dendron–polymer conjugates

Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper
Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis

Biomater. Sci., 2020, 8,2653-2665
DOI: 10.1039/D0BM00140F, Paper
Amit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. Nair
The study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Particle-mediated delivery of frataxin plasmid to a human sensory neuronal model of Friedreich's ataxia

Biomater. Sci., 2020, 8,2398-2403
DOI: 10.1039/C9BM01757G, Communication
Ewa Czuba-Wojnilowicz, Serena Viventi, Sara E. Howden, Simon Maksour, Amy E. Hulme, Christina Cortez-Jugo, Mirella Dottori, Frank Caruso
Multilayered particles in gene therapy for Friedreich's ataxia induce a 27 000-fold increase in frataxin gene expression in a patient-derived cell model.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A biomimetic orally targeted delivery of Bindarit for immunotherapy of atherosclerosis

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper
Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting CD44v6 receptor in colon cancer cells

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00556H, Paper
Ana Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno Sarmento
Colorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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RGD functionalized chitosan nanoparticle mediated targeted delivery of raloxifene selectively suppresses angiogenesis and tumor growth in breast cancer

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10673A, Paper
Amit S. Yadav, N. Naga Venkata Radharani, Mahadeo Gorain, Anuradha Bulbule, Dattatrya Shetti, Gaurab Roy, Thejus Baby, Gopal C. Kundu
Peptide functionalized pH sensitive raloxifene-chitosan nanoparticles with high biocompatibility synergistically inhibit tumor growth and angiogenesis in breast cancer.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy

Nanoscale, 2020, 12,9392-9403
DOI: 10.1039/D0NR00563K, Paper
Yifei Wang, Ruiting Wang, Sixuan Wu, Jingyi An, Yan Liang, Lin Hou, Zhenzhong Zhang
Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effective atherosclerotic plaque inflammation inhibition with targeted drug delivery by hyaluronan conjugated atorvastatin nanoparticles

Nanoscale, 2020, 12,9541-9556
DOI: 10.1039/D0NR00308E, Paper
Seyedmehdi Hossaini Nasr, Zahra Rashidijahanabad, Sherif Ramadan, Nate Kauffman, Narayanan Parameswaran, Kurt R. Zinn, Chunqi Qian, Ripla Arora, Dalen Agnew, Xuefei Huang
Atherosclerosis is associated with inflammation in the arteries. Hyaluronan atorvastatin nanoparticle conjugate could target CD44 overexpressed in atherosclerotic plaques and significantly reduce plaque associated inflammation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Near-infrared nanosecond-pulsed laser-activated high efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01792B, Paper
Tuhin Subhra Santra, Srabani Kar, Chih-Wei Chen, Jayant Borana, Te-Chang Chen, Ming-Chang Lee, Fan-Gang Tseng
Here, efficient intracellular delivery of molecules with high cell viability is reported using nanosecond-pulsed laser-activated plasmonic photoporation mediated by high-aspect-ratio nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles (nm-AuPNPs) at near-infrared wavelength. Upon...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Palm Beach, Florida - Delivering fresh milk, Key West, Fla




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Turner and Wilson Coffee delivery wagon




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Coca-cola delivery truck with driver and passenger




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Tampa Tribune staffers ready to deliver the newspaper after the Hurricane of 1921




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Glass delivery truck crossing the Gandy Bridge




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Delivery trucks at the Tampa Arctic Ice Company, Inc.




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Delivering continuing education in health education using self-directed computer-mediated instruction




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Synthesis and characterization of potential drug delivery systems using nonionic surfactant "niosome"




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The importance of program-delivered differential reinforcement in the development of classical music auditory discrimination




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Effects of aspirin and its derivatives in combination with electroporation for drug delivery in cultured cells




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School-based mental health services delivered by school psychologists




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Iontophoretic trans-dermal drug delivery through sweat glands




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A framework to develop an interactive web database for delivery of water resources field data over the internet




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The effect of computer-delivered phonological awareness training on the early literacy skills of students identified as at-risk for reading failure




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The role of organizational culture in the delivery of humanitarian assistance and inter-organizational collaboration




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Factors associated with school-based mental health services delivered by school psychologists




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Transport characteristics using nor-dihydroguaiaretic acid (NDGA)-polymerized collagen fibers as a local drug delivery system




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Online delivery of career choice interventions




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Can using one trainer solely to deliver prompts and feedback during role plays increase correct performance of parenting skills in a Behavioral Parent Training program?




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Intradermal delivery of plasmids encoding angiogenic growth factors by electroporation promotes wound healing and neovascularization




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Mental health service delivery systems and perceived qualifications of mental health service providers in school settings




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Recombinant AAV gene therapy and delivery for Alzheimer's disease




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[A truck delivering soft drinks to the docks]




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[The Dious Specialty Company delivery truck]




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[A Dious Specialty Company delivery truck]




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Delivery trucks inside the Coca-Cola warehouse




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[A delivery truck for Poinsettia Dairy Products displaying advertisements]




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[A delivery truck for Poinsettia Dairy Products]




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[The delivery vehicles of the Atlantic Ice Company]




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Hillsboro New Company delivery trucks




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Fred Herman's Sausage Plant and delivery truck




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Fred Herman's Sausage Plant and delivery truck




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Florida Wholesale Liquors Store with two gentlemen posing in front of a delivery truck




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Florida Wholesale Liquors Store and a delivery truck




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Line of Holsum Bakeries delivery trucks




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Fred Herman's Sausage tractor trailer delivery truck in front of the company




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Delivery truck




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Poinsettia Dairy Products delivery truck