Ticks that are able to transmit Lyme disease are more abundant in deciduous oak forests than pine forests, according to a study conducted in Belgium, which provides an example of how landscape can influence human health. To help prevent tick attacks and the incidence of Lyme disease, the researchers suggest increased efforts are needed to raise public awareness of control measures, such as protective clothing and repellants.

Community-focused eco-renovation firm Green Canopy Homes teams up with GMAC Mortgage to breathe new, green life into neglected, bank-owned properties across Sea

In exclusive and exceptionally irrigated Rancho Santa Fe, residents now face water rationing.

Say goodbye to the lumbering old Crown Vic, the new generation of Ford police cars can go from a stop to 100 mph in 14.5 seconds.

Citation Twitter For more about this, go here. Find out more at this site. Keywords: Washington dc server hosting, Cloud solutions, It managed services, Dedicated managed hosting, Boston business phone system, Seattle server hosting. Graphics: Share This Image

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Creators Launch Crowd funding Campaign to Fund Manufacturing and Distribution Cost of Their Redesigned Folding E-Bike

The update from Shorr's 2017 Package Theft Report shows a 7% decrease in respondents who experienced package theft.

This free Trip Planner is a perfect tool for travelers to discover new places, create a personalized itinerary, and have an organized vacation.

Starting 12/30/2019, new content will be posted, varying in subject matter from whether or not you can get a title loan on a motorcycle to the many ways you can have your loan disbursed to you.

As the season comes to a close, Occasion Brands, LLC (OB), releases this 2019 issue of Pulse of Homecoming to highlight the 2019 online dress sales trends for homecoming.

Peninsula General's website continues to offer a fast, online auto insurance quote system that was released in early September 2018.

Ibotdis.com offers significant discounts and coupons in time for prime holiday shopping season.

In the US, store closures are at an all-time high. 

Business Insider Intelligence

With 88% of total sales, brick-and-mortar is still the dominant driver of retail spend in the country, but in-store earnings aren't growing fast enough to keep the doors open.

See the rest of the story at Business Insider

See Also:

• The best Showtime TV shows of the last decade — and the worst
• Amazon's ad business looks strong despite the pandemic
• Amazon posts highest e-commerce growth in over three years

The sports brand enhanced its workflow with collaborative virtual reality

Josh Rushton writes: I’ve been following your blog for a while and checked in today to see if there was a thread on last week’s big-splash Stanford antibody study (the one with the shocking headline that they got 50 positive results in a “random” sample of 3330 antibody tests, suggesting that nearly 2% of the […]

Jeff Koeppel, a North Liberty businessman who played on Iowa’s football team from 1986 to 1989 — was a second-team All-Big Ten defensive lineman for two years — caught COVID-19...

A SOUTHAMPTON pub which underwent a £400,000 revamp is back on the market less than a year after reopening.

Richard Lutz reports on a step forward in opening the Moseley/Kings Heath train line.

40% Restaurants Face a Permanent Lockout; some entrepreneurs tweaking business models, selling DIY meal kits, attempting delivery.

Glasgow Clan head coach Zack Fitzgerald believes the Challenge Cup format needs a revamp.

Copyright 2020 NPR. To see more, visit https://www.npr.org.

Copyright 2020 NPR. To see more, visit https://www.npr.org.

A team of scientists at Oregon State University are trying to measure the true prevalence of the coronavirus in Corvallis, Ore., by taking a random sample of the population.

A team of scientists at Oregon State University are trying to measure the true prevalence of the coronavirus in Corvallis, Ore., by taking a random sample of the population.

The Narrogin Town Council is calling on the Western Australian Government to support upgrades to a wastewater treatment system, which it says is costing nearly $100,000 annually to maintain.

World number one Ash Barty is locked in to headline the 2020 Adelaide International, joining a strong list of female players including world number five Simona Halep.

A draft report has found a $260 million development of Glenorchy's Wilkinson's Point would great 1,100 jobs and inject millions into Hobart, but it could come at a cost to locals.

The redevelopment of the Royal Hobart Hospital continues to be beset with problems, the latest involving $1 million in construction damage.

Lakers star Anthony Davis was held to five points in the first half because of foul trouble but scored 25 points and had eight rebounds after halftime.

The fight over emissions between California and the White House could last years.

The Force was reportedly not with the original scripts of the anticipated show.

Contrarian bettors are off to their best start through the first four weeks of the season since 2003.

A mostly millennial crowd explored the upgraded and interactive museum.

Invitation Only Research Event

Monogenic forms of obesity have been identified in ≤10% of severely obese European patients. However, the overall spectrum of deleterious variants (point mutations and structural variants) responsible for childhood severe obesity remains elusive. In this study, we genetically screened 225 severely obese children from consanguineous Pakistani families through a combination of techniques including an in-house developed augmented whole-exome sequencing (CoDE-seq) enabling simultaneous detection of whole exome copy number variations (CNVs) and of point mutations in coding regions. We identified 110 probands (49%) carrying 55 different pathogenic point mutations and CNVs in 13 genes/loci responsible for non-syndromic and syndromic monofactorial obesity. CoDE-seq also identified 28 rare or novel CNVs associated with intellectual disability in 22 additional obese subjects (10%). Additionally, we highlight variants in candidate genes for obesity warranting further investigation. Altogether, 59% of the studied cohort are likely to have a discrete genetic cause with 13% of these due to CNVs demonstrating a remarkably higher prevalence of monofactorial obesity than hitherto reported and a plausible over lapping of obesity and intellectual disabilities in several cases. Finally, inbred populations with high prevalence of obesity, provide a unique genetically enriched material in quest of new genes/variants influencing energy balance.

Gunnar Stenström
Dec 1, 2005; 54:S68-S72
Section II: Type 1-Related Forms of Diabetes

Heading into his 13th year in the Majors, Cameron Maybin brings a fresh approach at the plate and a revamped swing as he looks to carve out playing time in the Giants' outfield.

The Alzheimer’s society, in the UK, predicts that if the rates of dementia remain constant there’ll be 1.7 million people in the country living with the condition by 2050. We also know that things like improvements in cardiovascular health are changing those rates. New research published on bmj.com attempts to model what the outcomes of those...

Precocious puberty, that is puberty that starts before age 8 in girls and 9 in boys seems to be on the rise, but whether that’s because of an increase in incidence, or greater attention is unknown - what we do know that precocious puberty in girls is commonly idiopathic, while in boys is a red flag for pathology. But either way ther first point of...

Charles M. Alexander
May 1, 2003; 52:1210-1214
Complications

Lipodystrophies are a group of disorders characterized by absence or loss of adipose tissue and abnormal fat distribution, commonly accompanied by metabolic dysregulation. Although considered rare disorders, their prevalence in the general population is not well understood. We aimed to evaluate the clinical and genetic prevalence of lipodystrophy disorders in a large clinical care cohort. We interrogated the electronic health record (EHR) information of >1.3 million adults from the Geisinger Health System for lipodystrophy diagnostic codes. We estimate a clinical prevalence of disease of 1 in 20,000 individuals. We performed genetic analyses in individuals with available genomic data to identify variants associated with inherited lipodystrophies and examined their EHR for comorbidities associated with lipodystrophy. We identified 16 individuals carrying the p.R482Q pathogenic variant in LMNA associated with Dunnigan familial partial lipodystrophy. Four had a clinical diagnosis of lipodystrophy, whereas the remaining had no documented clinical diagnosis despite having accompanying metabolic abnormalities. We observed a lipodystrophy-associated variant carrier frequency of 1 in 3,082 individuals in our cohort with substantial burden of metabolic dysregulation. We estimate a genetic prevalence of disease of ~1 in 7,000 in the general population. Partial lipodystrophy is an underdiagnosed condition. and its prevalence, as defined molecularly, is higher than previously reported. Genetically guided stratification of patients with common metabolic disorders, like diabetes and dyslipidemia, is an important step toward precision medicine.

OBJECTIVE

Diabetes is a rapidly growing health problem in low- and middle-income countries (LMICs), but empirical data on its prevalence and relationship to socioeconomic status are scarce. We estimated diabetes prevalence and the subset with undiagnosed diabetes in 29 LMICs and evaluated the relationship of education, household wealth, and BMI with diabetes risk.

Deborah J. Wexler
Feb 1, 2007; 30:367-369
BR Epidemiology/Health Services/Psychosocial Research

Massimo Cigolini
Mar 1, 2006; 29:722-724
BR Cardiovascular and Metabolic Risk

Rafael Simó
Sep 1, 1996; 19:998-1000
Short Report

Katherine M Flegal
Jul 1, 1991; 14:628-638
Supplement 3: Diabetes in Hispanic Americans

Johanna M Mooy
Sep 1, 1995; 18:1270-1273
Short Report