mortality

Objectively-Measured Light-Intensity Physical Activity and Risk of Cancer Mortality: A Meta-analysis of Prospective Cohort Studies

Background:

The impact of light-intensity physical activity (LPA) in preventing cancer mortality has been questioned. To address this concern, the present meta-analysis aimed to quantify the association between objectively-measured LPA and risk of cancer mortality.

Methods:

We conducted a systematic literature search in PubMed and Scopus to January 2020. Prospective cohort studies reporting the association between objectively-measured LPA using activity monitors (e.g., accelerometers) and risk of cancer mortality in the general population were included. The summary hazard ratios (HR) per 30 min/day of LPA and 95% confidence intervals (CI) were obtained using a random-effects model. Dose–response analysis was used to plot their relationship.

Results:

Five prospective cohort studies were included, in which the definition of LPA based on accelerometer readings was mainly set within 100 to 2,100 counts/min. The summary HR for cancer mortality per 30 min/day of LPA was 0.86 (95% CI, 0.79–0.95; I2 < 1%), and the association between LPA and risk reduction in cancer mortality was linearly shaped (Pnonlinearity = 0.72). LPA exhibited a comparable magnitude of risk reduction in cancer mortality of moderate-to-vigorous physical activity regardless of equal time-length (0.87 per 30 min/day vs. 0.94 per 30 min/day, Pinteraction = 0.46) or equal amount (0.74 vs. 0.94 per 150 metabolic equivalents-min/day, Pinteraction = 0.11). Furthermore, replacing sedentary time by LPA of 30 min/day decreased the risk of cancer mortality by 9%.

Conclusions:

Objectively-measured LPA conferred benefits in decreasing the risk of cancer mortality.

Impact:

LPA should be considered in physical activity guidelines to decrease the risk of cancer mortality.




mortality

Red and Processed Meat, Poultry, Fish, and Egg Intakes and Cause-Specific and All-Cause Mortality among Men with Nonmetastatic Prostate Cancer in a U.S. Cohort

Background:

Research on the relationship of meat, fish, and egg consumption and mortality among prostate cancer survivors is limited.

Methods:

In the Cancer Prevention Study-II Nutrition Cohort, men diagnosed with nonmetastatic prostate cancer between baseline in 1992/1993 and 2015 were followed for mortality until 2016. Analyses of pre- and postdiagnosis intakes of red and processed meat, poultry, fish, and eggs included 9,286 and 4,882 survivors, respectively. Multivariable-adjusted RRs and 95% confidence intervals (CI) were estimated using Cox proportional hazards models.

Results:

A total of 4,682 and 2,768 deaths occurred during follow-up in pre- and postdiagnosis analyses, respectively. Both pre- and postdiagnosis intakes of total red and processed meat were positively associated with all-cause mortality (quartile 4 vs. 1: RR = 1.13; 95% CI, 1.03–1.25; Ptrend = 0.02; RR = 1.22; 95% CI, 1.07–1.39; Ptrend = 0.03, respectively), and both pre- and postdiagnosis poultry intakes were inversely associated with all-cause mortality (quartile 4 vs. 1 RR = 0.90; 95% CI, 0.82–0.98; Ptrend = 0.04; RR = 0.84; 95% CI, 0.75–0.95; Ptrend = 0.01, respectively). No associations were seen for prostate cancer–specific mortality, except that higher postdiagnosis unprocessed red meat intake was associated with lower risk.

Conclusions:

Higher red and processed meat, and lower poultry, intakes either before or after prostate cancer diagnosis were associated with higher risk of all-cause mortality.

Impact:

Our findings provide additional evidence that prostate cancer survivors should follow the nutrition guidelines limiting red and processed meat consumption to improve overall survival. Additional research on the relationship of specific meat types and mortality is needed.




mortality

Total Antioxidant Capacity and Pancreatic Cancer Incidence and Mortality in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

Background:

Total antioxidant capacity (TAC) reflects an individual's overall antioxidant intake. We sought to clarify whether higher TAC is associated with lower risks of pancreatic cancer incidence and mortality in the U.S. general population.

Methods:

A total of 96,018 American adults were identified from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. A ferric-reducing ability of plasma score was used to reflect an individual's TAC intake from diet and/or supplements. Cox regression was used to calculate hazard ratios (HR) for pancreatic cancer incidence, and competing risk regression was used to calculate subdistribution HRs for pancreatic cancer mortality. Restricted cubic spline regression was used to test nonlinearity.

Results:

A total of 393 pancreatic cancer cases and 353 pancreatic cancer–related deaths were documented. Total (diet + supplements) TAC was found to be inversely associated with pancreatic cancer incidence (HR quartile 4 vs. quartile 1 = 0.53; 95% confidence interval, 0.39–0.72; Ptrend = 0.0002) and mortality (subdistribution HR quartile 4 vs. quartile 1 = 0.52; 95% confidence interval 0.38–0.72; Ptrend = 0.0003) in a nonlinear dose–response manner (all Pnonlinearity < 0.01). Similar results were observed for dietary TAC. No association of supplemental TAC with pancreatic cancer incidence and mortality was found.

Conclusions:

In the U.S. general population, dietary but not supplemental TAC level is inversely associated with risks of pancreatic cancer incidence and mortality in a nonlinear dose–response pattern.

Impact:

This is the first prospective study indicating that a diet rich in antioxidants may be beneficial in decreasing pancreatic cancer incidence and mortality.




mortality

Associations of Abdominal Skeletal Muscle Mass, Fat Mass, and Mortality among Men and Women with Stage I-III Colorectal Cancer

Background:

The associations of abdominal skeletal muscle mass index (SMI), visceral and subcutaneous adipose tissue (VAT and SAT, respectively), and mortality among patients with stage I–III colorectal cancer may differ for men and women, but only few studies stratified their data into men and women. We investigated associations of abdominal SMI, VAT, and SAT with overall mortality among men and among women with stage I–III colorectal cancer.

Methods:

SMI, VAT, and SAT were assessed from abdominal CT images for 1,998 patients with stage I–III colorectal cancer diagnosed between 2006 and 2015. Restricted cubic splines (RCS) were used to investigate associations of SMI, VAT, and SAT with overall mortality.

Results:

Average age of the participants was 67.9 ± 10.6 years and 58% were men. During a median follow-up of 4.3 years, 546 (27%) patients died. Among men, the association of SMI and mortality was statistically significant in a nonlinear way in the RCS analyses, with lower SMI levels associated with higher mortality. SMI was not associated with mortality among women. SAT was associated with mortality in a nonlinear way for men and for women, with lower SAT levels being associated with higher mortality. VAT was not significantly associated with mortality in men or women.

Conclusion:

Associations of abdominal skeletal muscle mass with mortality among patients with colorectal cancer were not the same for men and for women.

Impact:

This study stresses the importance for more attention on sex-related differences in body composition and cancer outcomes.




mortality

Pandemic Robots Deployed in Singapore Parks to Remind Humans of Their Own Mortality

As well as announcing reminders to stay away from each other, the robots also estimate how many people are in the park at any given time.




mortality

J-K witnesses decline in infant mortality rate




mortality

Vitamin D levels appear to play role in COVID-19 mortality rates

Researchers analyzed patient data from 10 countries. The team found a correlation between low vitamin D levels and hyperactive immune systems. Vitamin D strengths innate immunity and prevents overactive immune responses. The finding could explain several mysteries, including why children are unlikely to die from COVID-19.




mortality

A Multinational Effort to Reduce Neonatal Mortality: Interview with Dr. Maria Oden, Co-director of Rice 360° Institute for Global Health

According to the World Health Organization, 47% of childhood deaths worldwide occur in the first four weeks of life. This neonatal mortality rate is particularly prevalent in sub-Saharan Africa, where nearly one million newborns die every year. Many of these deaths can be prevented with medical devices that more developed countries often take for granted, […]




mortality

Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS-COVID-19 study




mortality

CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians




mortality

Class Notes: Selective College Admissions, Early Life Mortality, and More

This week in Class Notes: The Texas Top Ten Percent rule increased equity and economic efficiency. There are big gaps in U.S. early-life mortality rates by family structure. Locally-concentrated income shocks can persistently change the distribution of poverty within a city. Our top chart shows how income inequality changed in the United States between 2007 and 2016. Tammy Kim describes the effect of the…

       




mortality

Class Notes: Selective College Admissions, Early Life Mortality, and More

This week in Class Notes: The Texas Top Ten Percent rule increased equity and economic efficiency. There are big gaps in U.S. early-life mortality rates by family structure. Locally-concentrated income shocks can persistently change the distribution of poverty within a city. Our top chart shows how income inequality changed in the United States between 2007 and 2016. Tammy Kim describes the effect of the…

       




mortality

Class Notes: Selective College Admissions, Early Life Mortality, and More

This week in Class Notes: The Texas Top Ten Percent rule increased equity and economic efficiency. There are big gaps in U.S. early-life mortality rates by family structure. Locally-concentrated income shocks can persistently change the distribution of poverty within a city. Our top chart shows how income inequality changed in the United States between 2007 and 2016. Tammy Kim describes the effect of the…

       




mortality

The unreal dichotomy in COVID-19 mortality between high-income and developing countries

Here’s a striking statistic: Low-income and lower-middle income countries (LICs and LMICs) account for almost half of the global population but they make up only 2 percent of the global death toll attributed to COVID-19. We think this difference is unreal. Views about the severity of the pandemic have evolved a lot since its outbreak…

       




mortality

The unreal dichotomy in COVID-19 mortality between high-income and developing countries

Here’s a striking statistic: Low-income and lower-middle income countries (LICs and LMICs) account for almost half of the global population but they make up only 2 percent of the global death toll attributed to COVID-19. We think this difference is unreal. Views about the severity of the pandemic have evolved a lot since its outbreak…

       




mortality

Class Notes: Selective College Admissions, Early Life Mortality, and More

This week in Class Notes: The Texas Top Ten Percent rule increased equity and economic efficiency. There are big gaps in U.S. early-life mortality rates by family structure. Locally-concentrated income shocks can persistently change the distribution of poverty within a city. Our top chart shows how income inequality changed in the United States between 2007 and 2016. Tammy Kim describes the effect of the…

       




mortality

The unreal dichotomy in COVID-19 mortality between high-income and developing countries

Here’s a striking statistic: Low-income and lower-middle income countries (LICs and LMICs) account for almost half of the global population but they make up only 2 percent of the global death toll attributed to COVID-19. We think this difference is unreal. Views about the severity of the pandemic have evolved a lot since its outbreak…

       




mortality

Coronavirus outbreak: Maharashtra's mortality rate due to coronavirus is 4.24 percent, says Health Department

The mortality rate in Maharashtra due to coronavirus is 4.24 per cent said the State Health Department on Monday. "With 440 new COVID-19 cases, the total number of cases in Maharashtra has mounted to 8,068. Besides, the total number of deaths has reached 342 after 19 new deaths were reported," said an official statement from the Health Department.

The statement also said, "While India's mortality rate is 3.13%, the mortality rate in Maharashtra due to coronavirus is at 4.24 per cent."

According to the latest update by the Ministry of Health and Family Welfare, the total number of coronavirus cases in the country stands at 27,892, of which 6185 have recovered/migrated and 872 patients have succumbed to the disease.

Catch up on all the latest Crime, National, International and Hatke news here. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever




mortality

India's COVID-19 mortality rate lowest in world, over 10,000 patients discharged, says Harsh Vardhan

Union Health and Family Welfare Minister Dr Harsh Vardhan on Sunday said that India's COVID-19 mortality rate of 3.2 per cent is the lowest in the world and over 10,000 coronavirus patients have been discharged from hospitals after recovering from the disease so far.

"Today more than 10,000 COVID-19 patients have been discharged. Those still admitted at hospitals are on the road to recovery. If in last 14 days doubling rate was 10.5 days, then today it is around 12 days," the Minister told ANI after visiting Lady Hardinge Hospital.

"Our mortality rate of 3.2 per cent is the lowest in the world," he said. With 2,644 more COVID-19 cases and 83 deaths in the last 24 hours, the number of people infected from coronavirus in the country has reached 39,980 including 1,301 deaths, said the Union Ministry of Health and Family Welfare on Sunday.

Currently, there are 28,046 active cases while 10,633 COVID-19 positive patients have been cured/discharged.

Catch up on all the latest Crime, National, International and Hatke news here. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever




mortality

Due to Nursing Staff Shortfalls, Risk of Hospital Patient Mortality Increases

Nurses are the front-line caregivers to hospital patients, coordinating and providing direct care and delivering it safely and reliably. The goal for




mortality

Nurse to Patient Ratio Influences Patient Mortality Rates in the UK

Patient mortality rates are significantly lesser among nurses who take care of six patients than nurses who take care of more than ten, revealed a new study.




mortality

Research Unearths Publicly Funded Pregnancy-related Programs Can Improve Maternal Mortality Rates

The study conducted by FAU College of Business faculty members Patrick Bernet, Ph.D., Gulcin Gumus, Ph.D., and Sharmila Vishwasrao, Ph.D., and recently




mortality

J-K witnesses decline in infant mortality rate

Jammu and Kashmir has been able to achieve "remarkable improvement" in multiple indicators related to maternal and child health in recent years, with a decline in infant mortality rate (IMR), an official spokesman said. The IMR has been reduced from 52 (2005) to 22 (2018), according to the latest data released by the Registrar General of India in the SRS bulletin on Friday. "The current national average of infant mortality rate stands at 32 much higher than that of J-K," the spokesman said. "The entire Health and Medical Education Department with active support from the National Health Mission (NHM) has put in strenuous efforts to provide essential newborn care at government health institutions across the Union Territory," Atal Dulloo, the financial commissioner in Health and Medical Education Department, said. Special newborn care units (SNCUs) have been established in 27 districts and other equivalent hospitals, three NICUs, newborn stabilisation units (NBSUs) and newborn care ...




mortality

Mis-counting mortality


A recent report by Human Rights Watch, No Tally of the Anguish provides a much-needed exposure of the real story behind averages and official data about maternal mortality, writes Kalpana Sharma.




mortality

Social Stigma, Low Testing Behind WB's High Covid-19 Mortality Rate: Experts

Social stigma and low testing are the key reasons for the high mortality rate among COVID-19 patients in West Bengal, where the disease, like elsewhere in the country, is still an urban phenomenon, experts say.




mortality

With 396 Deaths in 6,600-plus Cases, Gujarat Has Worst Covid-19 Mortality Rate Among Most Affected States

Overall, the national mortality rate was 3.34 as on Friday morning and the recovery rate stood at 29.35 per cent. India has confirmed 56,342 confirmed Covid-19 cases so far.




mortality

From 52 in 2005 to 22 in 2018, Jammu and Kashmir Witnesses Decline in Infant Mortality Rate

To further decrease the infant mortality rate in the Union Territory to single digit by 2022, an action plan has been developed which is being implemented at various levels, a spokesman said.




mortality

Is COVID-19 Lockdown Increasing Suicide Mortality? A Study Based Approach

COVID-19 lockdown has affected the livelihood of many people worldwide. A study published on 3 April in a journal named JAMA Psychiatry says that in addition to the COVID-19 deaths due to infection or illness, people are also dying of suicides




mortality

Is COVID-19 Lockdown Increasing Suicide Mortality? A Study Based Approach

COVID-19 lockdown has affected the livelihood of many people worldwide. A study published on 3 April in a journal named JAMA Psychiatry says that in addition to the COVID-19 deaths due to infection or illness, people are also dying of suicides




mortality

Dapsone exposure and Australian Vietnam service : mortality and cancer incidence / [E.J Wilson, K.W Horsley, R. van der Hoek]




mortality

Melanoma Diagnoses Rise While Mortality Stays Fairly Flat, Raising Concerns About Overdiagnosis

This Medical News story examines the question of whether some melanomas might be better left undetected.




mortality

Having a word with Angus Graham: at twenty-five years into his immortality / edited by Carine Defoort and Roger T. Ames

Hayden Library - B1626.G74 H38 2018




mortality

State brings down infant mortality rate

Figure falls to 7, as against the UN-set target of 8 for 2020




mortality

The coronavirus and the Great Influenza Pandemic [electronic resource] : lessons from the "Spanish Flu" for the coronavirus's potential effects on mortality and economic activity / Robert J. Barro, José F. Ursúa, Joanna Weng

Cambridge, Mass. : National Bureau of Economic Research, 2020




mortality

Virtually human : the promise---and the peril---of digital immortality / Martine Rothblatt, Ph.D

Rothblatt, Martine Aliana, 1954-




mortality

Gujarat: Doctors plan study to reduce high infant mortality rate in tribal areas

SAVING FUTURE: The medical practitioner saYS 50-70 per cent of deaths take place within one month of birth




mortality

Annual Report to the Nation: Overall cancer mortality continues to decline; Special section on adults ages 20 to 49 shows higher cancer incidence and mortality for women than men

The 2019 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline and cancer incidence dropped in men and remained stable in women. A special section reports on recent cancer trends in younger adults.




mortality

Higher daily step count linked with lower all-cause mortality

In a new study, higher daily step counts were associated with lower mortality risk from all causes. Researchers found that the number of steps taken each day, but not the intensity of the stepping, had a strong association with mortality.




mortality

Increasing transparency in animal research to sway public opinion, and a reaching a plateau in human mortality

Public opinion on the morality of animal research is on the downswing in the United States. But some researchers think letting the public know more about how animals are used in experiments might turn things around. Online News Editor David Grimm joins Sarah Crespi to talk about these efforts. Sarah also talks Ken Wachter of the University of California, Berkeley about his group’s careful analysis of data from all living Italians born 105 or more years before the study. It turns out the risk of dying does not continue to accelerate with age, but actually plateaus around the age of 105. What does this mean for attempts to increase human lifespan? In this month’s book segment, Jen Golbeck talks with Simon Winchester about his book The Perfectionists: How Precision Engineers Created the Modern World. Read more book reviews at our books blog, Books et al. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Chris Jones/Flickr; Music: Jeffrey Cook]




mortality

Blood Pressure Patterns in Young Adulthood and Cardiovascular Disease and Mortality in Middle Age

This cohort study assesses whether long-term variability and rate of change of blood pressure from young adulthood to midlife are associated with cardiovascular disease and all-cause mortality by middle age.




mortality

Predicting Mortality and Morbidity in Chronic Heart Failure

This study developed and validated a prognostic prediction model for patients with heart failure.








mortality

JAMA Cardiology : Utility of 90-Day vs 30-Day Mortality Quality Metrics for Aortic Valve Replacement Outcomes

Interview with Tsuyoshi Kaneko, MD, and Sameer A Hirji, MD, authors of Utility of 90-Day Mortality vs 30-Day Mortality as a Quality Metric for Transcatheter and Surgical Aortic Valve Replacement Outcomes, and Michael J. Mack, MD, author of Ninety-Day Outcome Assessment After Transcatheter and Surgical Aortic Valve Replacement—Is the Juice Worth the Squeeze?







mortality

National and Regional Trends in Heart Failure Hospitalization and Mortality Rates for Medicare Beneficiaries, 1998-2008

Interview with Jersey Chen, MD, MPH, author of National and Regional Trends in Heart Failure Hospitalization and Mortality Rates for Medicare Beneficiaries, 1998-2008