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A jury convicted Arvind Ahuja yesterday on federal tax charges stemming from his failure to disclose offshore bank accounts maintained in India and the Bailiwick of Jersey, the Justice Department and Internal Revenue Service (IRS) announced. Trial began on Aug. 15, 2012 before U.S. District Judge Charles N. Clevert, Jr., in Milwaukee. Ahuja, a prominent neurosurgeon in Milwaukee, was convicted of one count of filing a false 2009 individual income tax return and one count of failing to file a Report of Foreign Bank and Financial Accounts (FBAR).

The Justice Department announced today that it has filed a complaint against Midwest Neurosurgeons L.L.C. and its owner, Dr. Sanjay Fonn, M.D., and DS Medical L.L.C. and its owner, Deborah Seeger, for allegedly violating the Medicare Anti-Kickback Statute and the False Claims Act by conspiring to solicit and receive commissions from medical device manufacturers related to the purchase of spinal implants and supplies used during spinal fusion surgeries performed by Dr. Fonn

The United States has filed two complaints under the False Claims Act against Michigan neurosurgeon Dr. Aria Sabit, spinal implant company Reliance Medical Systems, two Reliance distributorships—Apex Medical Technologies and Kronos Spinal Technologies—and the companies’ owners, Brett Berry, John Hoffman and Adam Pike.

Neuroscience has had a tough run of news lately. With Amgen deprioritizing neuro this year, Pfizer doing the same last year, and others like BMS, GSK, and AZ cutting back on CNS a few years earlier, it would seem dark

The post The Promise Of Precision Neuroscience And Launch Of Arkuda Therapeutics appeared first on LifeSciVC.

These pink and blue-tinted photographs suggest that our biology has a big influence on the way we perceive reality.

World-renowned doctor heads neurosurgery clinic at European Medical Center

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Michael Jackson

In the last few days, neurosurgeons Dr Sandeep Mohindra, Dr Manjul Tripathi and Dr Nishant S Yagnick, have all become mini celebrities at Chandigarh's Postgraduate Institute of Medical Education & Research (PGMIR). In between attending to OPD and other hospital duties, Mohindra and Yagnick have been fielding press questions, while Tripathi, currently in the UK pursuing a short course, has recorded a video to offer his version should the media approach. And, all this fuss is thanks to a 683-word paper that the trio submitted four weeks ago to The Journal of Neurosurgery which has been able to answer the question that many generations have pondered over: How did Michael Jackson manage his gravity-defying moves?

Blood on the Dance Floor
Mohindra, 45, and Tripathi, 39, have been working together for the last seven years. While Mohindra is an Additional Professor, Tripathi is an Assistant Professor and Yagnick, a registrar, has been with the institute for three years. Mohindra says the team of neurosurgeons at the institute had been reporting a lot of dance injuries — kids or amateur dancers coming in with spinal injuries from trying to copy dance moves off YouTube videos.

Dr Nishant S Yagnick and wife Shweta are amateur dancers, and regulars at contests and reallity shows

"While our textbooks have mechanisms of injury for certain sports or postures — say if you play cricket, this is the injury you are most prone to get, or this is how you will hurt yourself if you ride a bike without a helmet — not much research has been done in the field of dance. There are people turning on their heads and B-Boying, and when they come in with injuries, we wonder how they fractured these many vertebra in this specific way?"

The study began six months ago when Tripathi called in Yagnick, asking him to participate in a research to understand the bio-mechanics of certain moves. They zoomed in on MJ's anti-gravity lean which debuted in 1987.

Smooth Criminal
In the seventh minute of the video, Smooth Criminal, in which Jackson (then 29 years old), dressed in his trademark outfit, along with a group of dancers, leans forward — without bending his legs or taking any support — at an angle of 45 degrees. For the average human, this range is 20 degrees. "Medical science," says Mohindra, "fails when Jackson starts dancing."

The first thing that the trio found out was that a patent, registered under Jackson's name, made the move partially possible. "Along with fellow inventors, MJ developed a special shoe that had a slot in the heel. The triangular slot could engage a hitch member (a metallic peg, which emerged from the stage floor at just the right time), allowing the dancer to obtain the right amount of extra support to be able to lean forward beyond physiological limits. Alas, MJ's move was an illusionary trick." Yet, says Yagnick, even with this extra support, not everyone can do an MJ.

Dr Manjul Tripathi and Dr Sandeep Mohindra

Yagnick and his wife Shweta are both amateur dancers. While he has taken training in jazz and hip hop, his wife has added ballet, modern contemporary and Indian contemporary, to her repertoire. The couple regularly participates in reality shows, in fact in February they won a Punjab state-level contest. When the research idea was mooted, the couple tried to replicate the MJ lean, but realised that even with the support of the shoes, it was impossible. "We tried the angulation against the wall. Even when we held each other's feet and legs, we could not get his angulation," says Yagnick.

Speed Demon
There was then more to this. While studying various videos and trying to replicate the move, the doctors studied the muscles that come into play. To put it simply, when the human body leans forward, it's the core muscles (or the erector spinae muscles) that act like cables to support the suspended spinal column during the forward shift, preventing the body from toppling over. However, when the body leans further, the weight is transferred from the core to the to the ankle joints, "and strain is shifted to the Achilles tendon". The paper states: "This allows for a very limited degree of forward bending from the ankle joints, while keeping a stiff straight posture — unless you are Michael Jackson. Most trained dancers with strong core strength will reach a maximum of 25° to 30°..."

A] Drawings showing the "antigravity tilt" (>45° forward bend), the dance move introduced by Michael Jackson, in comparison to the normal limit of a human tilt (20° forward bend), as well as the conceptualized shoe designed by MJ and co-inventors. B] Shift of the fulcrum from the sacrum to the Achilles tendon in MJ's antigravity tilt; the pic on the right show MJ do the tilt in Smooth Criminal. Courtesy/Journal of Neurology

What then allowed Jackson to manage what few could? Several years of training and special exercises, not unlike perhaps what sprinters such as Usain Bolt perform daily. "If you see Bolt preparing for the 100 m dash, you will see the same forward bend," says Mohindra, adding, that for the most famous dancer in the world, the idea would have been to make his Achilles Tendon so strong that the two legs could hold his 60 kg weight when he shifted his weight on them. While the average tendon can hold 10k to 15 kg, for Jackson that weight almost doubled.

Heal The World
It could take months for a paper to get accepted by the Journal of Neurosurgery, but the curiosity of the gravity-defying lean is such that the journal's editor accepted it within 24 hours of submission. Not just that. Yagnick says they have been asked to continue the research with other dancers in order to understand where injuries originate and how some people, defy the spine. Hrithik Roshan, for instance, says Mohindra has scoliosis of spine i.e. an abnormal curve. "Yet, he is one of best dancers one has seen. He has, obviously trained his muscles to challenge these bio-mechanics."

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The European Union statistics agency, Eurostat, has released new figures concerning member states' tax revenue collections and their tax mixes for 2015.

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Cham, Switzerland : Springer, [2019]

Cham : Springer, c2019.

Dewey Library - HC240.25.S7 M37 2018

Ramsøy, Thomas Zoëga, author

Dewey Library - HF5415.32.C658673 2017

Dewey Library - PN1995.S38513 2020

Frewen, Paul, author

Beugré, Constant D., author

The Connectome is a comprehensive diagram of all the neural connections existing in the brain. WIRED has challenged neuroscientist Bobby Kasthuri to explain this scientific concept to 5 different people; a 5 year-old, a 13 year-old, a college student, a neuroscience grad student and a connectome entrepreneur.