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[ASAP] Asymmetric Synthesis of a Bacteriochlorophyll Model Compound Containing <italic toggle="yes">trans</italic>-Dialkyl Substituents in Ring D

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00608




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[ASAP] Further Insight into the Castagnoli–Cushman-type Synthesis of 1,4,6-Trisubstituted 1,6-Dihydropyridin-2-(3<italic toggle="yes">H</italic>)-ones from 3-Arylglutaconic Acid Anhydrides

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00836




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[ASAP] Chiral Vanadyl(V) Complexes Enable Efficient Asymmetric Reduction of ß-Ketoamides: Application toward (<italic toggle="yes">S</italic>)-Duloxetine

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00221




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[ASAP] Correction to Specific <italic toggle="yes">Z</italic>-Selectivity in the Oxidative Isomerization of Allyl Ethers to Generate Geometrically Defined <italic toggle="yes">Z</italic>-Enol Ethers Using a Coba

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00990




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[ASAP] Quantitative Kinetic Modeling in Photoresponsive Supramolecular Chemistry: The Case of Water-Soluble Azobenzene/Cyclodextrin Complexes

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00461




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[ASAP] Acylphloroglucinol Derivatives with a Tricyclo-[4.4.1.1<sup>1,4</sup>] Dodecane Skeleton from <italic toggle="yes">Garcinia bracteata</italic> Fruits

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00637




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[ASAP] Synthesis of Indolizine Derivatives Triggered by the Oxidative Addition of Aroyl Chloride to Pd(0) Complex

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00161




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[ASAP] Palladium-Catalyzed Synthesis of <italic toggle="yes">N</italic>,<italic toggle="yes">N-</italic>Dimethylanilines via Buchwald–Hartwig Amination of (Hetero)aryl Triflates

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00491




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[ASAP] Earth-Abundant Bimetallic Nanoparticle Catalysts for Aerobic Ammoxidation of Alcohols to Nitriles

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00670




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Target triggered ultrasensitive electrochemical polychlorinated biphenyl aptasensor based on DNA microcapsules and nonlinear hybridization chain reaction

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00065E, Paper
Ting Han, Shaozhen Wang, Feifan Sheng, Sicheng Wang, Tianyue Dai, Xiaojun Zhang, Guangfeng Wang
In this work, we demonstrated an ultrasensitive detection platform for polychlorinated biphenyls (PCBs) based on DNA microcapsules and a nonlinear hybridization chain reaction (NHCR).
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A polypyrrole-coated eightfold-helical Wells–Dawson POM-based Cu-FKZ framework for enhanced colorimetric sensing

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00402B, Paper
Qian Li, Mingqi Xu, Xiao Li, Shuxian Li, Liran Hou, Yuhao Chen, Jingquan Sha
A new Wells–Dawson-type CuFKZP2W18-based hybrid compound containing eightfold helical chains is reported, and its CuFKZP2W18/PPy(15%) composite exhibits excellent peroxidase-like catalytic activity.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A signal cascade amplification strategy based on RT-PCR triggering of G-quadruplex DNAzyme for a novel electrochemical detection of viable Cronobacter sakazakii

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00270D, Paper
Yuanyuan Yuan, Xianyong Wu, Zhanmin Liu, QIqi Ning, Liqiang Fu, Sujuan Wu
Cronobacter sakazakii is an important opportunistic food-borne pathogen, and it can cause severe diseases with main symptoms including neonatal meningitis, necrotizing enterocolitis, and sepsis. For the achievement of practical and...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A traceless clean-up method coupled with gas chromatography and mass spectrometry for analyzing polycyclic aromatic hydrocarbons in complex plant leaf matrices

Analyst, 2020, 145,3266-3273
DOI: 10.1039/D0AN00128G, Paper
Xiangzi Jin, Han Yeong Kaw, Huijie Li, Zhao Wang, Jinhua Zhao, Xiangfan Piao, Donghao Li, Dongri Jin, Miao He
This study developed a traceless clean-up method by combining solid phase extraction (SPE) with gas purge–microsyringe extraction (GP–MSE) to purify sample extracts for the determination of polycyclic aromatic hydrocarbons (PAHs) in plant leaves.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Trace manganese detection via differential pulse cathodic stripping voltammetry using disposable electrodes: additively manufactured nanographite electrochemical sensing platforms

Analyst, 2020, 145,3424-3430
DOI: 10.1039/D0AN00018C, Paper
Open Access
Diego P. Rocha, Christopher W. Foster, Rodrigo A. A. Munoz, Gary A. Buller, Edmund M. Keefe, Craig E. Banks
Additive manufacturing is a promising technology for the rapid and economical fabrication of portable electroanalytical devices.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Highly sensitive and selective optosensing of quercetin based on novel complexation with yttrium ions

Analyst, 2020, 145,3376-3384
DOI: 10.1039/D0AN00117A, Paper
Nguyen Ngoc Nghia, Bui The Huy, Yong-Ill Lee
A simple and fast method was developed for the determination of quercetin using a Arduino-based portable device.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Why ammonium detection is particularly challenging but insightful with ionophore-based potentiometric sensors – an overview of the progress in the last 20 years

Analyst, 2020, 145,3188-3210
DOI: 10.1039/D0AN00327A, Critical Review
Open Access
María Cuartero, Noemi Colozza, Bibiana M. Fernández-Pérez, Gastón A. Crespo
An overview of ionophore-based electrodes for ammonium sensing critically analyzing contributions in the last 20 years and with focus in analytical applications.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Paper-based platforms with coulometric readout for ascorbic acid determination in fruit juices

Analyst, 2020, 145,3431-3439
DOI: 10.1039/D0AN00477D, Paper
Estefanía Nunez-Bajo, M. Teresa Fernández-Abedul
Paper-based electrochemical platforms with coulometric readout are employed for fast and low cost determination of ascorbic acid in commercial juice samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Recent developments of nanoenzyme-based colorimetric sensors for heavy metal detection and the interaction mechanism

Analyst, 2020, 145,3173-3187
DOI: 10.1039/D0AN00339E, Critical Review
Zhengquan Yan, Hua Yuan, Qi Zhao, Lin Xing, Xiaoyu Zheng, Weiguo Wang, Yulei Zhao, Yang Yu, Lei Hu, Wenli Yao
This work highlights the application and interaction mechanism of metal nanoparticles, metal oxides, metal sulfides, graphene-based nanomaterials and G-quadruplex, etc. in nanoenzyme-based colorimetric sensors.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Novel ratiometric electrochemical sensor for no-wash detection of fluorene-9-bisphenol based on combining CoN nanoarrays with molecularly imprinted polymers

Analyst, 2020, 145,3320-3328
DOI: 10.1039/D0AN00345J, Paper
Zhaoyi Liu, Yong Zhang, Bing Li, Xiang Ren, Hongmin Ma, Qin Wei
A ratiometric molecularly imprinted polymers electrochemical sensor was fabricated based on the direct electrochemical oxidation of BHPF on CoN nanoarray electrode.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Colorimetric identification of lanthanide ions based on two carboxylic acids as an artificial tongue

Analyst, 2020, 145,3359-3363
DOI: 10.1039/D0AN00357C, Paper
Chi Zhang, Juan Huang, Wei Wei, Zhengbo Chen
We report a colorimetric array, which consists of two carboxylic acids (quinolinic acid (QA), tannic acid (TCA)) as the sensor element and Eriochrome Black T (EBT) as the colorimetric signal readout.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Selective ratiometric red-emission detection of In3+ in aqueous solutions and in live cells using a fluorescent peptidyl probe and metal chelating agent

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00288G, Paper
Joohee Park, Hyeongseok Yu, See-Hyoung Park, Keun-Hyeung Lee
A ratiometric fluorescent detection method for In3+ in aqueous buffered solution, ground water, and live cells was developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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FRET based fluorescent ratiometric probes for rapid detection of endogenous hydrogen sulphide in living cells

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00531B, Paper
Yuming Zhang, Yuncong Chen, Bai Yang, Xueling Xue, Weijiang He, Zijian Guo
Real time monitor of hydrogen sulphide (H2S) level change is of crucial importance for the study of its complicated roles in physiology. Herein, we developed a FRET strategy for designing...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Driving Force to Detect Alzheimer's Disease Biomarkers: The Application Of A Thioflavine T@Er-MOF Ratiometric Fluorescent Sensor for Smart Detection of Presenilin 1, amyloid β-protein and Acetyl Choline

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00440E, Paper
Xing Ze Wang, jing du, Nannan Xiao, Yan Zhang, Ling Fei, Jed D. LaCoste, Zhuo Huang, Qian wang, Xin Rui Wang, Bin Ding
Currently, the highly sensitive detection of Alzheimer's Disease (AD) biomarkers, namely presenilin 1, amyloid β-protein (Aβ), and acetylcholine (ACh), are vital to helping us prevent and diagnose AD. In this...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Phenyl doped graphitic carbon nitride nanosheets for sensing of copper ions in living cells

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00795A, Paper
Zhiping Song, Yuanteng Xu, Liangqia Guo
Copper (Cu) is a vital mental element for human and animals. Monitoring and evaluating the concentration level of Cu2+ in biological body is an effective way to prevent a variety...
The content of this RSS Feed (c) The Royal Society of Chemistry




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[ASAP] Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00202




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[ASAP] Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01936




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[ASAP] Design of Radiolabeled Analogs of Minigastrin by Multiple Amide-to-Triazole Substitutions

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01937




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[ASAP] Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00395




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[ASAP] Both <sc>d</sc>- and <sc>l</sc>-Glucose Polyphosphates Mimic <sc>d</sc>-<italic toggle="yes">myo</italic>-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00215




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[ASAP] Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00192




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[ASAP] Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin—Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00441




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[ASAP] Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00661




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Tanzania turns to solar power to increase electricity connectivity

As many as 60 percent of the Kenyan population now has access to electricity according to official data. But in neighbouring Tanzania, the penetration rate is less than half of that and sparsely populated rural communities are especially neglected.  

The post Tanzania turns to solar power to increase electricity connectivity appeared first on LatestSolarNews.




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Styling with STRINGS

At this year’s CSSConf in Melbourne (AU) I gave a talk called “Styling with STRINGS”. The talk is about how we can use Flexbox, currentColor and __EM__s inside components to quickly style entire Web Apps straight in the browser.

In case of tl:dw here some of the main points:

Layout

When creating mobile “App” layouts, where not the whole page is scrollable, but instead only certain parts. And you have anchored areas like header/footer and a main area that should fill out the available space, then the easiest way is to use Flexbox.

This lets you easily drag around components that are set as flex items and they always position nicely. Using flex: 1; on components makes them stretch out and fill the available space. A good use case is a search input or a title.

Color

If you don’t specify the border-color (initial value) it will be the same value as color.

Furthermore there is a color value called currentColor. As the name indicates, it’s also mapped to the current color value. We can use it as background-color for example. Not that useful when the text should be readable, since now text and background are the same color, but for some components without text it can be quite useful. Like in the example below with the slider thumb.

If a component set should look similar to the “iOS 7” style then currentColor works great. Below all components have no color values at all and only use currentColor. This let’s us change everything by only changing the color value in the root html element.

Size

In a similar way, EMs are mapped to font-size. So if we use EMs to define only the proportions of a component, we can use font-size to scale it up/down. And if we inherit the font-size we could also control everything at once with just a single property in the root or in groups if we go deeper down the DOM tree.

REMs work the same except that they are tied to the root html element only. We could use it to control the spacing of the components by using REMs for margin/padding.

I wrote about this in more detail in the Sizing (Web) Components post.

All together

Now if we combine this all and test it in an example application, we can easily design many variations right from the DevTools/inspector in a quick and easy way.

Feel free to play around with the CSSConf App yourself or check out the source on GitHub.

How to save?

You might wonder how you can save the changes made in the DevTools/inspector without having to manually copy them over into your CSS file. In Chrome there is a feature called Workspaces. It let’s you map a URL to a local folder. Once that is setup, all CSS changes will automatically be saved to your local disc. Here a post that explains how to setup Workspaces. It’s advised to use version control like Git, so that you can always discard all changes if you went too far and wanna start over.

Conclusion

Admittedly it is somewhat in between of being useful for production and just a “hack”. Especially the currentColor. But the main point of the talk is best told by this quote:

“Creators need an immediate connection” — Bret Victor

The examples I used are just the closest I could get using CSS alone and still keep code clean. I hope we keep that principle alive and improve on it.


ps. Artist of the puppet master illustration: Unknown.

pss. Here all the other videos from CSSConf.




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The matter of photography in the Americas / Natalia Brizuela and Jodi Roberts ; with contributions by Lisa Blackmore, Amy Sara Carroll, Marianela D'Aprile, María Fernanda Domínguez, Heloisa Espada, Rachel Price, Diana Ruiz, Tatiane Santa Ro

Rotch Library - TR184.B75 2018




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Legacy of the masters: painting and calligraphy of the Islamic world from the Shavleyan family collection / Will Kwiatkowski ; with contributions by John Seyller

Rotch Library - N6260.K87 2019




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Fields of fungus and sunflowers / [edited and designed by Tammy Nguyen ; contributions by Lovely Umayam and Adriel Luis]

Rotch Library - N7433.35.U6 M37 no.6




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Beatriz Milhazes: rio azul / White Cube

Rotch Library - N6659.M55 A4 2018




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April in Paris: theatricality, modernism, and politics at the 1925 Art Deco Expo / Irena R. Makaryk

Hayden Library - N6493 1925.M35 2018




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My dearest Aiyana / [contributors, Daniil Davydoff, Naima Green, and Tuan Andrew Nguyen ; edited by Tammy Nguen]

Rotch Library - N7433.35.U6 M37 no.7




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T.C. Cannon: at the edge of America / edited by Karen Kramer ; with contributions by heather ahtone, Sherwin Bitsui, Caitlin Cooper, Frank Buffalo Hyde, Trevor Fairbrother, Santee Frazier, Joy Harjo, Joan Naviyuk Kane, Karen Kramer, Deana McCloud, America

Rotch Library - NX512.C36 A4 2018




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Conversation pieces: the world of Bruegel / Abdelkader Benali, Alexandra van Dongen, Katrien Lichtert, Sabine Pénot, Lucinda Timmermans ; translation, Patrick Lennon, Michael Lomax

Rotch Library - ND673.B73 B46 2018




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Model as painting / Pieter Schoolwerth ; contributors, Pieter Schoolwerth, David Geers, Molly Warnock ; editor: Katherine Pickard

Rotch Library - N6537.S3589 A4 2019




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Mary Corse: a survey in light / Kim Conaty ; with contributions from Robin Clark, Michael Govan, Alexis Lowry, and David Reed

Rotch Library - N6537.C663 A4 2018




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Matrimania: Mahesh Shantaram / editors, Jeroen Kummer, Vidya Rao

Rotch Library - TR819.S53 2018




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The lady from the black lagoon: Hollywood monsters and the lost legacy of Milicent Patrick / Mallory O'Meara

Dewey Library - NC1766.U52 P38 2019




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Bestowing beauty: masterpieces from Persian lands-selections from the Hossein Afshar collection / edited by Aimée Froom ; with essays by Walter B. Denny, Aimée Froom, Melanie Gibson, and David J. Roxburgh; and contributions by Robert Hillenbrand

Rotch Library - N7280.B47 2019




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Arabicity: contemporary Arab art / edited by Rose Issa and Juliet Cestar ; contributions by Rose Issa, Georges Corm, Michket Krifa, Etel Adnan

Rotch Library - N7265.3.A733 2019




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Gauguin: portraits / edited by Cornelia Homburg, Christopher Riopelle ; with contributions by Elizabeth C. Childs [and five others]

Rotch Library - ND553.G27 A4 2019




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Stripped bare: the art of animal anatomy / David Bainbridge

Hayden Library - NC780.B35 2018