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Delivery of dual miRNA through CD44-targeted mesoporous silica nanoparticles for enhanced and effective triple-negative breast cancer therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00015A, Paper
Manisha Ahir, Priyanka Upadhyay, Avijit Ghosh, Sushmita Sarker, Saurav Bhattacharya, Payal Gupta, Swatilekha Ghosh, Sreya Chattopadhyay, Arghya Adhikary
Cationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual miRNA loading, efficient delivery and significantly inhibited tumor growth as well as retarded metastasis in triple-negative breast cancer.
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Long-term delivery of alendronate through an injectable tetra-PEG hydrogel to promote osteoporosis therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00376J, Paper
Dawei Li, Jin Zhou, Mingming Zhang, Yuanzheng Ma, Yanyu Yang, Xue Han, Xing Wang
An alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy and bone regeneration.
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Assembly of FN-silk with laminin-521 to integrate hPSCs into a three-dimensional culture for neural differentiation

Biomater. Sci., 2020, 8,2514-2525
DOI: 10.1039/C9BM01624D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carolina Åstrand, Veronique Chotteau, Anna Falk, My Hedhammar
The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
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Prometryn induces apoptotic cell death through cell cycle arrest and oxidative DNA damage

Toxicol. Res., 2019, 8,833-841
DOI: 10.1039/C9TX00080A, Paper
Qiaoyun Liu, Longsheng Wang, Hanwen Chen, Bo Huang, Jiawei Xu, Ying Li, Paul Héroux, Xinqiang Zhu, Yihua Wu, Dajing Xia
Prometryn induces oxidative stress-mediated DNA damage; Prometryn induces S phase of cell cycle arrest; Prometryn induces Bax-dependent apoptosis in BEAS-2B cells.
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Integrated network pharmacology and targeted metabolomics to reveal the mechanism of nephrotoxicity of triptolide

Toxicol. Res., 2019, 8,850-861
DOI: 10.1039/C9TX00067D, Paper
Wei Huang, Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo Li
Integrated network pharmacology and targeted metabolomics to reveal the nephrotoxicity mechanism of triptolide.
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Thyroid endocrine status and biochemical stress responses in adult male Wistar rats chronically exposed to pristine polystyrene nanoplastics

Toxicol. Res., 2019, 8,953-963
DOI: 10.1039/C9TX00147F, Paper
Fatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad Babaei
At this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.
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Cytotoxic effect of silica nanoparticles against hepatocellular carcinoma cells through necroptosis induction

Toxicol. Res., 2019, 8,1042-1049
DOI: 10.1039/C9TX00240E, Paper
Yuexiang Niu, Engong Tang, Qingan Zhang
Hepatocellular carcinoma (HCC) is a common cancer that affects people worldwide with high morbidity and mortality, and its resistance to current chemotherapeutic drugs is a serious concern.
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Plasma-assisted filling electron beam lithography for high throughput patterning of large area closed polygon nanostructures

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01032D, Paper
You Sin Tan, Hailong Liu, Qifeng Ruan, Hao Wang, Joel K. W. Yang
The PFEBL process allows enhancement of electron beam writing efficiency for patterning of closed polygon structures using a post-exposure plasma treatment.
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A three-dimensional Cu nanobelt cathode for highly efficient electrocatalytic nitrate reduction

Nanoscale, 2020, 12,9385-9391
DOI: 10.1039/C9NR10743F, Paper
Xiaodan Wang, Mengqi Zhu, Guoshen Zeng, Xun Liu, Chihhsiang Fang, Chuanhao Li
A three-dimensional Cu nanobelt cathode was developed to efficiently catalyze the electrocatalytic nitrate reduction process.
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Clear observation of the formation of nanoparticles inside the ablation bubble through a laser-induced flat transparent window by laser scattering

Nanoscale, 2020, 12,9640-9646
DOI: 10.1039/C9NR10560C, Paper
Kota Ando, Takashi Nakajima
We demonstrate the clear observation of laser-scattering signals from Ag nanoparticles (NPs) inside an ablation bubble.
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Near-infrared nanosecond-pulsed laser-activated high efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01792B, Paper
Tuhin Subhra Santra, Srabani Kar, Chih-Wei Chen, Jayant Borana, Te-Chang Chen, Ming-Chang Lee, Fan-Gang Tseng
Here, efficient intracellular delivery of molecules with high cell viability is reported using nanosecond-pulsed laser-activated plasmonic photoporation mediated by high-aspect-ratio nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles (nm-AuPNPs) at near-infrared wavelength. Upon...
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Die neuesten Digitalisate der Bayerischen Staatsbibliothek aus dem 17. Jahrhundert

Logo des MDZ




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Three Rivers Regional Library System




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Sabal palm, our state tree, grows throughout Florida




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Hindu temple with Christian cross is meditation spot




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San-ai-an, "the adobe of three loves"




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Permanent Christmas tree symbol of love




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Randall House had first inside bathroom




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Pensacola's "new" Christ Church not new




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Historic St. Paul's Organized Christmas Day, 1832




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Site of the nation's first Christmas




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Implementation of low impact development in modern urbanization as exampled through capstone design




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Reactions to natural and man-made radioactive threat




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Social response to the 1994 Northridge California earthquake




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There and where again : a watershed's tale : use of macroinvertebrate indicators in the Río Guacimal Watershed to indicate changes in water conditions over time and present anthropogenic impact




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Wet-season throughfall in primary and secondary tropical montane gorests, Monteverde, Costa Rica




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The marriage record of Collins, Jasper C. and Rodgers, Sophronia L




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The marriage record of Thrasher, W. C. and Platt, Damares P




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The marriage record of Shannon, Charles H. and Chrestman, Lillie




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The marriage record of Buoyer, Joseph and Bolesta, Saphronia Julia




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The marriage record of Southsibehan, Maxamiliano and Hranas, Rita de




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The marriage record of Whitehurst, Williard W. and Haghr, Bell V




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The marriage record of Waller, Nicholas O. and Hewbury, Sophronia




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The marriage record of McHraine, Victor B. and Taylor, Caralyne M




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The marriage record of Burger, August and Mahre, Burtha




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The marriage record of Crews, Henry and Bryant, Christine




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The marriage record of Hardy, D. M. and Swain, Saphronia




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The marriage record of Holden, Christopher C. and Goodrich, Lizzie




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The marriage record of Green, Christopher C. and Howard, Vinie




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The marriage record of Smith, Christopher c. and Small, Mary




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The marriage record of McCall, Benjamin G. and Humphries, Lula M




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The marriage record of Smith, Ephrom and Hutchinson, Anna




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The marriage record of Verbeck, Eli J. and Thrasher, Annie




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The marriage record of Thrall, H. E. and Davis, Annie




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Three cows and an African American man stand in a small pasture by a stream and outbuilding




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Small stream passing through a quiet forest in Virginia




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Amos Slaymaker and his three daughters




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Yglesia del S. Christo




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Gordon Keller School of Nursing Christmas party




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Three nurses and man with bandaged foot