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Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein




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Coldest Canadian Arctic communities face greatest reductions in shorefast sea ice




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Lipids: Cardioprotective effects of HDL cholesterol called into question




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With Coronavirus, ‘Nature is sending us a message’, says UN Environment Chief

Prof Andrew Cunningham from the Zoological Society of London said, “The emergence of COVID-19 was not only predictable, but it was also predicted (in the sense that) there would be another viral emergence from wildlife that would be a public health threat.”

 




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Rajasthan signs reworked Barmer refinery MoU with HPCL

Rajasthan signed a MoU with HPCL over the reworking of Barmer refinery in the state. The deal was finalised in the presence of Rajasthan’s CM Vasundhara Raje.




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The multifaceted long-term effects of the COVID-19 pandemic on urology




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4 Days to Go for SED Punjab Recruitment 2020: Apply Online for 1664 ETT Teacher Posts before 31 March, Details Here

Punjab Education Board Punjab Recruitment 2020 Online Application Last Date Extended at educationrecruitmentboard.com. Check details here.






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Therapeutic efficacy of Pudilan Xiaoyan Oral Liquid (PDL) for COVID-19 in vitro and in vivo




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A high-quality reference genome of wild <i>Cannabis sativa</i>




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MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3β/β-catenin signaling




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Gene conversion following CRISPR/Cas9 DNA cleavage: an overlooked effect




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Advances in genome editing: the technology of choice for precise and efficient β-thalassemia treatment




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CD24Fc protects against viral pneumonia in simian immunodeficiency virus-infected Chinese rhesus monkeys




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An analysis of the effect of mu-opioid receptor gene (<i>OPRM1</i>) promoter region DNA methylation on the response of naltrexone treatment of alcohol dependence




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Cost-effectiveness of <i>CYP2C19-</i>guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data




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Mechanisms of graft-versus-leukemia effects after allogeneic stem cell transplantation: effects on the leukemia stem cell?




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Daily briefing: How desperate measures might shorten the coronavirus vaccine timeline — and at what risk




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Effect of non-pharmaceutical interventions to contain COVID-19 in China




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Daily briefing: Convalescent serum — the antibody-laden blood of survivors — lines up as first-choice treatment for coronavirus




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Daily briefing: More than 1 billion people face unbearable temperatures within 50 years




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Daily briefing: Closest black hole ever discovered was ‘hiding in plain sight’




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Whole-genome sequencing of a sporadic primary immunodeficiency cohort




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Smart-technology spies, a final warning on the environment, and the staggering costs of cancer: Books in brief




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Daily briefing: A dark-matter detector powered by the ‘fifth state of matter’




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Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer




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Urate-lowering therapy exerts protective effects against hypertension development in patients with gout




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Effects of chronic type 5 phosphodiesterase inhibition on penile microvascular reactivity in hypertensive patients with erectile dysfunction: a randomized crossover placebo-controlled trial




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Novel sGC stimulator improves outcomes in patients with HFrEF




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Apixaban therapy is effective and safe for cancer-associated VTE




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No benefit of initial invasive strategy for managing CAD in advanced CKD




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Cardiovascular effects and safety of (non-aspirin) NSAIDs




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Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons




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Within-group synchronization in the prefrontal cortex associates with intergroup conflict




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Dynamic regulation of Z-DNA in the mouse prefrontal cortex by the RNA-editing enzyme Adar1 is required for fear extinction




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The functions of IL-23 and IL-2 on driving autoimmune effector T-helper 17 cells into the memory pool in dry eye disease




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Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals




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Parkinson disease Primer - a true team effort




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Effectiveness of the adjunctive use of ozone and chlorhexidine in patients with chronic periodontitis




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Comparative efficacy of a hydroxyapatite and a fluoride toothpaste for prevention and remineralization of dental caries in children




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Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes




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Exposure to direct-to-consumer advertising is associated with overestimation of benefits regarding ultrahypofractionated radiation therapy for prostate cancer




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Effect of simulated microgravity on the antidiabetic properties of wheatgrass (<i>Triticum aestivum</i>) in streptozotocin-induced diabetic rats

npj Microgravity, Published online: 24 February 2020; doi:10.1038/s41526-020-0096-x

Effect of simulated microgravity on the antidiabetic properties of wheatgrass (Triticum aestivum) in streptozotocin-induced diabetic rats




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How does spaceflight affect the acquired immune system?

npj Microgravity, Published online: 07 May 2020; doi:10.1038/s41526-020-0104-1

How does spaceflight affect the acquired immune system?




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Safety and efficacy of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma with renal impairment




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Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells




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The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors




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QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism




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NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas