Throughout Asia and the world, digital solutions are being found for urban problems. Policymakers and city leaders should ensure that the poor do not get left behind in this digital transformation of cities.

在整个亚洲乃至全世界，许多城市难题通过数字技术得到了解决。政策制定者和城市领导者应确保贫困人口在城市数字化转型中一个都不能少。

By some estimates, the digital economy now accounts for trillions of dollars. But policymakers and companies still lack the data needed to fully understand it.

Bank-held nonperforming loans in some Asian economies have risen in recent years. Policy makers should address this growing risk now.

The Government of Palau will draw down on a $15 million policy-based loan from ADB's Disaster Resilience Program to help finance the country’s response to the novel coronavirus disease (COVID-19) pandemic.

ADB today announced the release of a $6 million grant from its Pacific Disaster Resilience Program (Phase 2) to help finance the Government of the Marshall Islands’ response to the novel coronavirus disease (COVID-19) pandemic.

ADB President Masatsugu Asakawa and Pakistan’s Federal Minister for Economic Affairs and ADB Governor Makhdoom Khusro Bukhtiar today discussed how ADB can scale up its support for the government’s response to the COVID-19...

The Asian Development Bank (ADB) has provided a guarantee for a $25 million trade loan to the State Pharmaceuticals Corporation of Sri Lanka (SPC) to purchase medical supplies as part of the country’s response to the novel ....

The Mumbai Metropolitan Region Development Authority (MMRDA) has begun the construction of 3.1 km-long new Metro Line 7A. The proposed metro corridor would comprise two stations and would connect Line 7 with the Chhatrapati Shivaji International Airport. The Mumbai Metropolitan Region Development Authority (MMRDA) has commenced the development of the Metro Line 7A.  The reach of the new metro would be 3.1 km, out of which 2.1 km-long section would be underground and would include a twin-tunnel. The corridor would establish connectivity between Metro Line 7 and the Chhatrapati Shivaji International Airport. Other areas that are expected to benefit from the improved connectivity include Andheri and Dahisar (East). According to an MMRDA […]

During the early 1900s, the city of Mumbai witnessed an unprecedented peak in social, artistic, and cultural activity. At the center of this movement was the Royal Opera House, Mumbai, India’s ‘cultural crown jewel’ and only surviving opera house. Built...

MUMBAI, INDIA – HARMAN Professional Solutions, the global leader in audio, video, lighting and control systems, including networked AV, today announced popular fusion rock band Swarathma, Rajasthani folk singer Mame Khan and percussionist Darshan Doshi...

On Make Music Day 2019, people across the globe will pick up an instrument to celebrate the joy of making music – including some for the very first time! It’s an indescribable feeling and one that you must experience for yourself. Known for his work with...

At HARMAN, it’s our mission to develop state-of-the-art audio solutions that provide enhanced listening experiences for music lovers at home, on the road, and on-stage. In recognition of Make Music Day 2018, we spoke with William “Bootsy” Collins,...

All over the world, people and societies are adjusting to social distancing and a long-term work-from-home environment. Students and teachers too are now adapting to virtual classes, quickly mastering and equipping themselves with all tools necessary to...

Thousands of pink-plumed flamingos were spotted in a lake in India's western Maharashtra state on Friday.

Title: Lumbar Puncture (LP or Spinal Tap)
Category: Procedures and Tests
Created: 10/13/1998 12:00:00 AM
Last Editorial Review: 12/13/2019 12:00:00 AM

For any journal issue that has at least one open access or early access article, PMC is now displaying the table of contents (TOC) in advance of the whole issue becoming available. Not to worry, though—only those articles specified for early release are immediately viewable in PMC. As consistent with the terms of access in the journal agreement, the other articles will only become available on their specified release date, as shown in the TOC below.

The journal's accessiblity, as indicated on the PMC Journal list also has not changed; for example, Plant Physiology's embargo period is still 12 months. What has changed is that the issues with “preview” TOCs now additionally appear on the journal's archive page. Publishers and others can rest assured, however, that no access terms for any journal have been changed with the unveiling of this new format.

Title: Cymbalta (duloxetine)
Category: Medications
Created: 7/11/2007 12:00:00 AM
Last Editorial Review: 2/12/2020 12:00:00 AM

Most British railway embankments were constructed between 120 and 180 years ago without the benefit of modern design and construction methods. This can result in undesirable load-deformation characteristics and consequent disruption to present-day railway operations, for which there is unprecedented demand. Annual rail passenger kilometres have approximately doubled in the last 20 years and freight has increased by 60% over the same period. Whereas elements such as rails or bridges can be refurbished or replaced to meet increasing demand, the same is not usually feasible for embankments. Development of techniques to assess embankment performance risks posed by operational capacity enhancements is therefore of increasing significance to railway geotechnical asset management. The two case studies presented in this paper demonstrate how geospatial analysis and data management techniques may be applied to this challenge at both strategic (regional or national) and tactical (site-specific) scales for embankments incorporating plastic clay fill. The case studies also demonstrate, in a world of ever more abundant data, the growing need for engineering geologists and geotechnical engineers to augment their traditional knowledge with comprehensive data management and geospatial analysis skills, these being essential for modern infrastructure asset management.

Thematic collection: This article is part of the ‘Ground-related risk to transportation infrastructure’ collection available at: https://www.lyellcollection.org/cc/Ground-related-risk-to-transportation-infrastructure

A longstanding awareness in generating resistance to common antimicrobial therapies by Gram-negative bacteria has made them a major threat to global health. The application of antimicrobial peptides as a therapeutic agent would be a great opportunity to combat bacterial diseases. Here, we introduce a new antimicrobial peptide (~8.3 kDa) from probiotic strain Lactobacillus acidophilus ATCC 4356, designated acidocin 4356 (ACD). This multifunctional peptide exerts its anti-infective ability against Pseudomonas aeruginosa through an inhibitory action on virulence factors, bacterial killing, and biofilm degradation. Reliable performance over tough physiological conditions and low hemolytic activity confirmed a new hope for the therapeutic setting. Antibacterial kinetic studies using flow cytometry technique showed that the ACD activity is related to the change in permeability of the membrane. The results obtained from molecular dynamic (MD) simulation were perfectly suited to the experimental data of ACD behavior. The structure-function relationship of this natural compound, along with the results of transmission electron microscopy analysis and MD simulation, confirmed the ability of the ACD aimed at enhancing bacterial membrane perturbation. The peptide was effective in the treatment of P. aeruginosa infection in mouse model. The results support the therapeutic potential of ACD for the treatment of Pseudomonas infections.

IMPORTANCE Multidrug-resistant bacteria are a major threat to global health, and the Pseudomonas bacterium with the ability to form biofilms is considered one of the main causative agents of nosocomial infections. Traditional antibiotics have failed because of increased resistance. Thus, finding new biocompatible antibacterial drugs is essential. Antimicrobial peptides are produced by various organisms as a natural defense mechanism against pathogens, inspiring the possible design of the next generation of antibiotics. In this study, a new antimicrobial peptide was isolated from Lactobacillus acidophilus ATCC 4356, counteracting both biofilm and planktonic cells of Pseudomonas aeruginosa. A detailed investigation was then conducted concerning the functional mechanism of this peptide by using fluorescence techniques, electron microscopy, and in silico methods. The antibacterial and antibiofilm properties of this peptide may be important in the treatment of Pseudomonas infections.

Rất nhiều khách hàng bất ngờ với trải nghiệm độc đáo và tiện lợi khi sử dụng sản phẩm cho vay mua nhà của Techcombank từ đầu tháng 9 vừa qua.

Publisher Warner Bros. Interactive Entertainment and developer NetherRealms Studios have announced a new expansion for Mortal Kombat 11 called Aftermath. It will release on May 26.

The Mortal Kombat 11: Aftermath expansion adds a new cinematic story, three characters and three new skins for $39.99. The three new characters are Fujin, Sheeva, and RoboCop).

A $59.99 Mortal Kombat: Aftermath Kollection has also been announced. It includes the base game, Kombat Pack DLC and the Aftermath expansion. 

View the announcement trailer for the expansion and RoboCop reveal trailer below:

Here is an overview of the expansion:

Mortal Kombat 11: Aftermath is a new expansion for the hit videogame, Mortal Kombat 11, the best-selling title in franchise history that was named Fighting Game of the Year at the 2019 D.I.C.E. Awards. Developed by award-winning NetherRealm Studios, Mortal Kombat 11: Aftermath expands the critically acclaimed story campaign with an all-new, cinematic narrative centered around trust and deceit, while also adding new playable characters in returning Mortal Kombat fighters, Fujin and Sheeva, and guest character, RoboCop, who is making his series debut.

Key Features:

• Franchise-First Story Expansion – The critically acclaimed story campaign continues with an all-new cinematic narrative that picks up directly where Mortal Kombat 11 left off. Fire God Liu Kang, the new keeper of time and protector of Earthrealm, must now enlist the help of unlikely allies and familiar foes to forge a new history as the fate of two worlds hang in the balance.
• Exciting New Characters Join the Roster – New playable characters join the fight with the triumphant return of Fujin, the God of Wind who serves as Earthrealm’s protector alongside his brother Raiden, and Sheeva, the fourarmed, half-human and half-dragon queen of the ancient Shokan race. RoboCop, the iconic, highly advanced cybernetic police officer, makes his first appearance in the franchise, continuing the pedigree of popular Mortal Kombat guest fighters. RoboCop in Mortal Kombat 11: Aftermath features the voice and likeness of actor Peter Weller, who portrayed the popular character in both the original RoboCop (1987) film and RoboCop 2 (1990) sequel. Mortal Kombat 11: Aftermath will also include three new character skin packs to be released over time.
• Fan-Favorite Stages, Stage Fatalities & Friendships Return – In conjunction with the Mortal Kombat 11: Aftermath release, all Mortal Kombat 11 owners will have access to a free content update featuring new Stages, including the return of the Klassic Dead Pool and Soul Chamber arenas; Stage Fatalities, the fan-favorite finishing moves that use the environment to destroy opponents; and the popular Friendships feature, allowing players to take down their adversaries with a hint of kindness.
• New Players Can Join the Fight with Mortal Kombat 11: Aftermath Kollection – Offers the perfect opportunity for new players to join the fight, featuring all characters, story content, game modes and pre-order bonuses in one ultimate package. This compilation includes Mortal Kombat 11 along with all content from Mortal Kombat 11: Aftermath and the previously released Mortal Kombat 11 Kombat Pack, containing six playable characters—Shang Tsung, Nightwolf, Sindel, Terminator T-800, The Joker and Spawn – plus 25 additional character skins. The Mortal Kombat 11: Aftermath Kollection can be pre-ordered for $59.99 (SRP) with digital pre-orders offering immediate access to Mortal Kombat 11 and the Kombat Pack upon purchase. The physical version will be available this June in the Americas only.
• Upgrade Options for Current Mortal Kombat 11 Owners – Those who have already purchased Mortal Kombat 11 can pre-order the Mortal Kombat 11 Aftermath expansion for $39.99 (SRP) or the Mortal Kombat 11: Aftermath + Kombat Pack Bundle for $49.99 (SRP).
• Pre-order for Exclusive Content – All preorders* receive the Eternal Klash Skin Pack at launch, featuring three new character skin variants – “Unbound Rage” Scorpion inspired by Mortal Kombat (2011), “Son of Arctika” Sub-Zero inspired by Mortal Kombat: Deception and “Kori Power” Frost, a Klassic version of the Lin Kuie warrior.
• Best-In-Class, Brutal Kombat – Mortal Kombat 11 is the latest installment in the critically acclaimed franchise, providing a deeper and more personalized experience than ever before. The best-selling title is packed to the brim with multiple features and modes for all players, including the Story mode, Custom Character Variation System, Towers of Time, Kombat League, The Krypt and the signature roster returning and franchise-first fighters, all equipped with powerful Krushing Blows and unique Fatalities that display devastatingly brutal cinematic visuals.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443404/mortal-kombat-11-aftermath-expansion-announced-adds-3-new-characters-and-new-story/

Marissa Guale is like all too many Americans right now. Her husband and father of her two children, Raul, is on a ventilator in a hospital on Long Island, fighting for his life while sick with COVID-19. Raul, a 34-year-old nurse, likely caught the disease while working in a nursing home. When the National Institutes of Health announced an emergency use authorization for the experimental antiviral drug remdesivir, Marissa scrambled friends and family on Facebook to figure out how to get access for Raul, emailing hospital administrators, senators, and doctors. They pressed the Guale family’s case for a potentially lifesaving treatment on social media to anyone who would listen.

Her confusion about where and how to get access to the drug isn’t unique. All over the country, families, doctors, and hospitals are wondering how to get the drug and on what basis it’s being distributed. The Trump administration, which is in charge of allocation, hasn’t published any guidance on how it’s making decisions about the scarce supplies of the drug.

So who decides which hospitals get remdesivir? And what’s the most ethical way to prioritize access?

Read more at The Daily Beast.

Alice has returned, has delivered missiles, and has many stories of Final Fantasy inspired cafés. Anna Marie is still busting Ba’als. Jonathan has begun a...

Around 250 Indian students and tourists were seen queuing with their luggage at the airport as they prepared for the journey home.

Kylian Mbappe and Neymar Jr's friendship is not limited to Paris Saint Germain but also off the field. The recent example of the same could be the French footballer's recent post on social media. Mbappe posted a picture of himself on social media where he was seen playing basketball. This was quite an ideal opportunity for Neymar Jr to pull his teammate's leg and he hilariously trolled the footballer with a funny comment.

Virat Kohli and Anushka Sharma have contributed Rs 5 lakh each for police welfare as the world battles coronavirus.

Follow our live coronavirus updates HERE Coronavirus: the symptoms

China's ambassador to the UK has criticised MPs for "attacking" China over the coronavirus outbreak.

The year-old band also called on Zygnema’s Sidharth Kadadi to produce their second release

The post Exclusive Premiere: Mumbai Metallers Targe Call on The Demonstealer for ‘The Cortege’ appeared first on My Site.

UK scientists provide a new estimate for the amount of space rock falling to Earth each year.

1. ‘I seriously can’t believe it,’ Rohit Sharma recalls IPL hat-trick against Mumbai Indians  Hindustan Times
2. Ricky Ponting's pep talk changed Mumbai Indians' fortunes?  NEWS9 live
3. I will finish before that..; Rohit Sharma reveals his ‘retirement age’ to David Warner - Republic World  Republic World
4. ‘He’s an idiot’: Rohit recalls hilarious incident from 2013 Champions Trophy when he started opening...  Hindustan Times
5. Not Chennai Super Kings! Rohit Sharma names franchise for whom Mumbai Indians plan for hours  Times Now
6. View Full coverage on Google News

1. ED attaches Rs 16.38 crore worth of Mumbai AJL asset; names Moti Lal Vora  Times of India
2. National Herald case: ED attaches part of Bandra building worth Rs 16 crore  Hindustan Times
3. ED attaches Rs 16.38 cr worth of Mumbai AJL asset; names Vora  The Financial Express
4. ED attaches Rs 16.38 cr worth of Mumbai AJL asset; names Moti Lal Vora  Economic Times
5. National Herald case: ED attaches part of nine-storey Mumbai building, Congress slams move  Hindustan Times
6. View Full coverage on Google News

Some of these firms have strong balance sheets and credible financials to support this frenzy.

Ambassador Joao Cravinho, head of the EU delegation, led Ambassadors of various European countries to a quiet lunch with Modi at the capital last year.

Covid Live: Mumbai case-count tops 12,000Total cases in India have risen to 59,662 and 1,981 deaths so far ( including 39834 active cases, 17847 cured/discharged.)

The star will read the entire Tolkien book from start to finish with no breaks.

As cities and states come out of COVID-19 stay-at-home orders, Uber is working on technologies to ensure both drivers and riders have masks in place.

Hello gentle readers, and welcome to the SwitchArcade Round-Up for May 7th, 2020. Like most Thursdays, today is mostly about …

Continue reading "SwitchArcade Round-Up: ‘Mortal Kombat 11: Aftermath’ Coming May 26th, ‘Slayin 2’ and Today’s Other New Releases, the Latest Sales, and More"

And the France World Cup winner 'won't sign a new contract' with the Ligue1 giants

Real Madrid may have missed out on signing Kylian Mbappe this summer due to the coronavirus.

Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.

The current break due to coronavirus has seen the rumour mill in overdrive. With no football happening on the pitch, transfer talk is dominating the sports pages.

PSG and France star Kylian Mbappe's valuation could drop to as little as €40million because of the coronavirus pandemic, according to French MEP Daniel Cohn-Bendit.

Former Arsenal and Chelsea midfielder Cesc Fabregas says PSG star Kylian Mbappe is the one player he would sign if he was a manager and money was no object.

Matteo Darmian has backed former Manchester United team-mate Marcus Rashford to "reach the level" of Paris Saint-Germain star Kylian Mbappe in future and even contend for the prestigious Ballon d'Or award.