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'NOT recommended under any circumstances': Health Ministry issues advisory on use of disinfectant on people

Several images and videos have emerged from different parts of the country where authorities are using disinfectant on people as part of the strategy against coronavirus.




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Disaster Relief Aid [electronic resource] : Changes and Challenges / by Bimal Kanti Paul

Paul, Bimal Kanti, author




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Education Policy, Digital Disruption and the Future of Work [electronic resource] : Framing Young People's Futures in the Present / by Shane B. Duggan

Duggan, Shane B., author




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Eurovision and Australia [electronic resource]: Interdisciplinary Perspectives from down Under




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Gender, Work and Social Control [electronic resource]: A Century of Disability Benefits

Gulland, Jackie




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Leading in a VUCA World [electronic resource] : Integrating Leadership, Discernment and Spirituality / edited by Jacobus (Kobus) Kok, Steven C. van den Heuvel




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Neuroimaging, Software, and Communication [electronic resource] : The Social Code of Source Code / by Edison Bicudo

Bicudo, Edison, author




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Bis(ethylmaltolato)oxidovanadium(IV) inhibited the pathogenesis of Alzheimer's disease in triple transgenic model mice

Metallomics, 2020, 12,474-490
DOI: 10.1039/C9MT00271E, Paper
Zhijun He, Shuangxue Han, Chong Wu, Lina Liu, Huazhang Zhu, Ang Liu, Qiying Lu, Jingqiang Huang, Xiubo Du, Nan Li, Qinguo Xie, Lu Wan, Jiazuan Ni, Lingling Chen, Xiaogai Yang, Qiong Liu
BEOV activates PPARγ to affect JAK2/STAT3/SOCS1 signaling and eventually prevents Aβ generation. Meanwhile, BEOV inactivates PTP1B to affect PI3K/Akt/GSK3β signaling and finally reduces tau hyperphosphorylation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Distribution and chemical form of selenium in Neptunia amplexicaulis from Central Queensland, Australia

Metallomics, 2020, 12,514-527
DOI: 10.1039/C9MT00244H, Paper
Maggie-Anne Harvey, Peter D. Erskine, Hugh H. Harris, Gillian K. Brown, Elizabeth A. H. Pilon-Smits, Lachlan W. Casey, Guillaume Echevarria, Antony van der Ent
Elemental mapping of selenium in the hyperaccumulator Neptunia amplexicaulis determined whole plant and tissue level selenium distribution. The total concentrations and chemical forms of selenium are also reported for this species.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lanthanum chloride impairs spatial learning and memory by inducing [Ca2+]m overload, mitochondrial fission–fusion disorder and excessive mitophagy in hippocampal nerve cells of rats

Metallomics, 2020, 12,592-606
DOI: 10.1039/C9MT00291J, Paper
Miao Yu, Jinghua Yang, Xiang Gao, Wenchang Sun, Shiyu Liu, Yarao Han, Xiaobo Lu, Cuihong Jin, Shengwen Wu, Yuan Cai
Lanthanum chloride damages hippocampal nerve cells of rats through inducing [Ca2+]m overload, mitochondrial fission–fusion disorder, and excessive mitophagy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Bis(ethylmaltolato)oxidovanadium(IV) inhibited the pathogenesis of Alzheimer's disease in triple transgenic model mice

Metallomics, 2020, 12,631-631
DOI: 10.1039/D0MT90008G, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Zhijun He, Shuangxue Han, Chong Wu, Lina Liu, Huazhang Zhu, Ang Liu, Qiying Lu, Jingqiang Huang, Xiubo Du, Nan Li, Qingguo Xie, Lu Wan, Jiazuan Ni, Lingling Chen, Xiaogai Yang, Qiong Liu
The content of this RSS Feed (c) The Royal Society of Chemistry




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Diphenyl Diselenide Protects Caenorhabditis elegans Model for Huntington's Disease by Activation of Antioxidant Pathway and Decrease in Protein Aggregation

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00074D, Paper
Fabiane Bicca Obetine Baptista, Marina Lopes Machado, Aline da Silva Franzen, Larissa Marafiga Cordeiro, Tassia da Silveira, Leticia Arantes, Félix A. A. Soares
Huntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease with a distinct phenotype. It occurs due to a mutation in huntingtin (or IT19) gene with abnormal CAG repeat, leading...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A liver-targeting Cu(I) chelator relocates Cu in hepatocytes and promotes Cu excretion in a murine model of Wilson’s disease

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00069H, Paper
Marie Monestier, AnaÏS M. Pujol, Aline Lamboux, Martine Cuillel, Isabelle Pignot-Paintrand, Doris Cassio, Peggy Charbonnier, Khémary Um, Amélie Harel, Sylvain BOHIC, Christelle GATEAU, Vincent Balter, Virginie Brun, Pascale Delangle, Elisabeth Mintz
Copper chelation is the most commonly used therapeutic strategy nowadays to treat Wilson’s disease, a genetic disorder primarily inducing a pathological accumulation of Cu in the liver. The mechanism of...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The study of levels from redox-active elements in cerebrospinal fluid of amyotrophic lateral sclerosis patients carrying disease-related gene mutations shows potential copper dyshomeostasis

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00051E, Paper
Federica Violi, Nikolay Solovyev, Marco Vinceti, Jessica Mandrioli, Marianna Lucio, Bernhard Michalke
Gene-environment interaction is as a possible key factor in the development of ALS. The levels of redox species of Cu, Fe, and Mn were assessed in cerebrospinal fluid, showing a possible positive association between Cu and genetic ALS.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Evidence that levels of nine essential metals in post-mortem human-Alzheimer's-brain and ex vivo rat-brain tissues are unaffected by differences in post-mortem delay, age, disease staging, and brain bank location

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00048E, Paper
Melissa Scholefield, Stephanie J. Church, Jingshu Xu, Sarah Kassab, Natalie J. Gardiner, Federico Roncaroli, Nigel M. Hooper, Richard D. Unwin, Garth J. S. Cooper
Metal findings in human Alzheimer brains are consistent despite differences in sample post-mortem delay, age, Braak stage and biobank location.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Disqualification case of 7 MLAs : Tribunal reserves judgement

Disqualification case of 7 MLAs : Tribunal reserves judgement




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[ASAP] Magnetic Bead-Immobilized Mammalian Cells Are Effective Targets to Enrich Ligand-Displaying Yeast

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00036




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NCI study finds long-term increased risk of cancer death following common treatment for hyperthyroidism

Findings from a new NCI study of patients who received radioactive iodine (RAI) treatment for hyperthyroidism show an association between the dose of treatment and long-term risk of death from solid cancers, including breast cancer.




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The colonial fantasy : why white Australia can't solve black problems / Sarah Maddison

Maddison, Sarah, author




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Shi sheng jiao yu hua yu yan jiu = Educational discourse study between teachers and students / Hu Zhiqi zhu

Hu, Zhiqi




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Za rou yu hui tong : ci hui yu yi xue yu xiu ci de jiao cha yan jiu = Mingling and mastery : an interdisciplinary study of lexical semantics and rhetoric / Liu Zhuo zhu

Liu, Zhuo, author




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Tondemo redīsu komikku no gyakushū / Karasawa Shun'ichi ; Sorubonnu Kko ; Sorubonnu Kko




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[ASAP] Fragrant Venezuelaenes A and B with A 5–5–6–7 Tetracyclic Skeleton: Discovery, Biosynthesis, and Mechanisms of Central Catalysts

ACS Catalysis
DOI: 10.1021/acscatal.0c01575




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216 districts in country have not reported any COVID-19 cases till now: Health ministry

The ministry asserted that if dos and don'ts are followed, the peak in number of COVID-19 cases can be avoided.




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Aufräumen: Roman / Angelika Waldis

Hayden Library - PT2685.A4556 A97 2013




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Nietzsche's ontology Laird Addis

Online Resource




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Handbuch der deutsch-jüdischen Literatur / herausgegeben von Hans Otto Horch

Online Resource




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Science Podcast - Human odor discrimination and a news roundup (21 Mar 2014)

Human odor discrimination; roundup of daily news with David Grimm.




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The Deepwater Horizon disaster: Five years later.

5th Anniversary of the Deepwater Horizon disaster: Marcia McNutt discusses the role of science in responding to the Deepwater Horizon oil spill in the Gulf of Mexico. Warren Cornwall examines the state of ecological recovery 5 years later. Hosted by Susanne Bard. [Img: © Bryan Tarnowski/Science Magazine]




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How the measles virus disables immunity to other diseases and a news roundup

Michael Mina discusses how measles destroys immunity to other infectious diseases and why the measles vaccine has led to disproportionate reductions in childhood mortality since its introduction 50 years ago, and David Grimm discusses daily news stories. Hosted by Susanne Bard. [Img: UNICEF Ethiopia/Creative Commons License BY-NC-ND 2.0, via flickr]




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3-parent gene therapy for mitochondrial diseases and a news roundup

Kimberly Dunham-Snary discusses the long-term health considerations of gene therapy for mitochondrial diseases and David Grimm talks about the smell of death, Mercury crashing, and animal IQ. Hosted by Susanne Bard. [Image credit: Ben Gracewood CC BY-NC 2.0, via flickr]




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Podcast: A recipe for clean and tasty drinking water, a gauge on rapidly rising seas, and fake flowers that can fool the most discerning insects

Online News Editor Catherine Matacic shares stories on what we can learn from 6million years of climate data, how to make lifelike orchids with 3D printing, and crowdsourced gender bias on eBay.   Fernando Rosario-Ortiz joins host Sarah Crespi to discuss how approaches to water purification differ between countries.   [Image: Eric Hunt/Wikipedia/CC BY-SA 3.0] 0]




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Podcast: Pollution hot spots in coastal waters, extreme bees, and diseased dinos

News stories on bees that live perilously close to the mouth of a volcano, diagnosing arthritis in dinosaur bones, and the evolution of the female orgasm, with David Grimm.  From the magazine Rivers deliver water to the ocean but water is also discharged along the coast in a much more diffuse way. This “submarine groundwater discharge” carries dissolved chemicals out to sea. But the underground nature of these outflows makes them difficult to quantify.  Audrey Sawyer talks with Sarah Crespi about the scale of this discharge and how it affects coastal waters surrounding the United States.  [Image: Hilary Erenler/Music: Jeffrey Cook]




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The sound of a monkey talking, cloning horses for sport, and forensic anthropologists help the search for Mexico’s disappeared

This week, we chat about what talking monkeys would sound like, a surprising virus detected in ancient pottery, and six cloned horses that helped win a big polo match with Online News Editor David Grimm. Plus, Science’s Alexa Billow talks to news writer Lizzie Wade about what forensic anthropologists can do to help parent groups find missing family members in Mexico.   Listen to previous podcasts.   [Image: (c) Félix Márquez; Music: Jeffrey Cook]




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Podcast: An ethics conundrum from the Nazi era, baby dinosaur development, and a new test for mad cow disease

This week, we chat about how long dinosaur eggs take—or took—to hatch, a new survey that confirms the world’s hot spots for lightning, and replenishing endangered species with feral pets with Online News Editor Catherine Matacic. Plus, Science’s Alexa Billow talks to Megan Gannon about the dilemma presented by tissue samples collected during the Nazi era. And Sarah Crespi discusses a new test for mad cow disease with Kelly Servick.   Listen to previous podcasts.   [Image: NASA/flickr; Music: Jeffrey Cook]




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Podcast: The archaeology of democracy, new additions to the uncanny valley, and the discovery of ant-ibiotics

This week, what bear-mounted cameras can tell us about their caribou-hunting habits, ants that mix up their own medicine, and feeling alienated by emotional robots with Online News Editor David Grimm. And Lizzie Wade joins Sarah Crespi to discuss new thinking on the origins of democracy outside of Europe, based on archeological sites in Mexico. Listen to previous podcasts. Download the show transcript. Transcripts courtesy of Scribie.com. [Image: rpbirdman/iStockphoto; Music: Jeffrey Cook]




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The dangers of dismantling a geoengineered sun shield and the importance of genes we don’t inherit

Catherine Matacic—online news editor for Science—talks with Sarah Crespi about how geoengineering could reduce the harshest impacts of climate change, but make them even worse if it were ever turned off. Sarah also interviews Augustine Kong of the Big Data Institute at the University of Oxford in the United Kingdom about his Science paper on the role of noninherited “nurturing genes.” For example, educational attainment has a genetic component that may or may not be inherited. But having a parent with a predisposition for attainment still influences the child—even if those genes aren’t passed down. This shift to thinking about other people (and their genes) as the environment we live in complicates the age-old debate on nature versus nurture. Listen to previous podcasts. [Image: Collection of Dr. Pablo Clemente-Colon, Chief Scientist National Ice Center; Music: Jeffrey Cook]




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How humans survived an ancient volcanic winter and how disgust shapes ecosystems

When Indonesia’s Mount Toba blew its top some 74,000 years ago, an apocalyptic scenario ensued: Tons of ash and debris entered the atmosphere, coating the planet in ash for 2 weeks straight and sending global temperatures plummeting. Despite the worldwide destruction, humans survived. Sarah Crespi talks with Online News Editor Catherine Matacic about how life after Toba was even possible—were humans decimated, or did they rally in the face of a suddenly extra hostile planet? Next, Julia Buck of the University of California, Santa Barbara, joins Sarah to discuss her Science commentary piece on landscapes of disgust. You may have heard of a landscape of fear—how a predator can influence an ecosystem not just by eating its prey, but also by introducing fear into the system, changing the behavior of many organisms. Buck and colleagues write about how disgust can operate in a similar way: Animals protect themselves from parasites and infection by avoiding disgusting things such as dead animals of the same species or those with disease. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Emma Forsber/Flickr; Music: Jeffrey Cook]




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What we can learn from a cluster of people with an inherited intellectual disability, and questioning how sustainable green lawns are in dry places

A small isolated town in Colombia is home to a large cluster of people with fragile X syndrome—a genetic disorder that leads to intellectual disability, physical abnormalities, and sometimes autism. Spectrum staff reporter Hannah Furfaro joins host Sarah Crespi to discuss the history of fragile X in the town of Ricaurte and the future of the people who live there. Also this week, we talk about greening up grass. Lawns of green grass pervade urban areas all around the world, regardless of climate, but the cost of maintaining them may outweigh their benefits. Host Meagan Cantwell talks with Maria Ignatieva of The University of Western Australia in Perth and the Swedish University of Agricultural Sciences in Uppsala about how lawns can be transformed to contribute to a more sustainable future. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Adam Kerfoot-Roberts/Flickr; Music: Jeffrey Cook]




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How the appendix could hold the keys to Parkinson’s disease, and materials scientists mimic nature

For a long time, Parkinson’s disease was thought to be merely a disorder of the nervous system. But in the past decade researchers have started to look elsewhere in the body for clues to this debilitating disease—particularly in the gut. Host Meagan Cantwell talks with Viviane Labrie of the Van Andel Institute in Grand Rapids, Michigan, about new research suggesting people without their appendixes have a reduced risk of Parkinson’s. Labrie also describes the possible mechanism behind this connection. And host Sarah Crespi talks with Peter Fratzl of the Max Planck Institute of Colloids and Interfaces in Potsdam, Germany, about what materials scientists can learn from nature. The natural world might not produce innovations like carbon nanotubes, but evolution has forged innumerable materials from very limited resources—mostly sugars, proteins, and minerals. Fratzl discusses how plants make time-release seedpods that are triggered by nothing but fire and rain, the amazing suckerin protein that comprises squid teeth, and how cicadas make their transparent, self-cleaning wings from simple building blocks. Fratzl’s review is part of a special section in Science on composite materials. Read the whole package, including a review on using renewables like coconut fiber for building cars and incorporating carbon nanotubes and graphene into composites. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Roger Smith/Flickr; Music: Jeffrey Cook]




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Spotting slavery from space, and using iPads for communication disorders

In our first segment from the annual meeting of AAAS (Science’s publisher) in Washington, D.C., host Sarah Crespi talks with Cathy Binger of University of New Mexico in Albuquerque about her session on the role of modern technology, such as iPads and apps, in helping people with communication disorders. It turns out that there’s no killer app, but some devices do help normalize assistive technology for kids. Also this week, freelance journalist Sarah Scoles joins Sarah Crespi to talk about bringing together satellite imaging, machine learning, and nonprofits to put a stop to modern-day slavery. In our monthly books segment, books editor Valerie Thompson talks with Judy Grisel about her book Never Enough: The Neuroscience and Experience of Addiction, including discussions of Gisel’s personal experience with addiction and how it has informed her research as a neuroscientist. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: ILO in Asia and the Pacific/Flickr; Music: Jeffrey Cook]




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Race and disease risk and Berlin’s singing nightingales

Noncancerous tumors of the uterus—also known as fibroids—are extremely common in women. One risk factor, according to the scientific literature, is “black race.” But such simplistic categories may actually obscure the real drivers of the disparities in outcomes for women with fibroids, according to this week’s guest. Host Meagan Cantwell speaks with Jada Benn Torres, an associate professor of anthropology at Vanderbilt University in Nashville, about how using interdisciplinary approaches— incorporating both genetic and cultural perspectives—can paint a more complete picture of how race shapes our understanding of diseases and how they are treated. In our monthly books segment, book review editor Valerie Thompson talks with David Rothenberg, author of the book Nightingales in Berlin: Searching for the Perfect Sound, about spending time with birds, whales, and neuroscientists trying to understand the aesthetics of human and animal music. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Carlos Delgado/Wikipedia; Matthias Ripp/Flickr; Music: Jeffrey Cook]




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An app for eye disease, and planting memories in songbirds

Host Sarah Crespi talks with undergraduate student Micheal Munson from Baylor University in Waco, Texas, about a smartphone app that scans photos in the phone’s library for eye disease in kids.  And Sarah talks with Todd Roberts of the University of Texas Southwestern Medical Center in Dallas, Texas, about incepting memories into zebra finches to study how they learn their songs. Using a technique called optogenetics—in which specific neurons can be controlled by pulses of light—the researchers introduced false song memories by turning on neurons in different patterns, with longer or shorter note durations than typical zebra finch songs. This week’s episode was edited by Podigy. Ads on this week’s show: MOVA Globes; KiwiCo.com Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast  




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Researchers flouting clinical reporting rules, and linking gut microbes to heart disease and diabetes

Though a law requiring clinical trial results reporting has been on the books for decades, many researchers have been slow to comply. Now, 2 years after the law was sharpened with higher penalties for noncompliance, investigative correspondent Charles Piller took a look at the results. He talks with host Sarah Crespi about the investigation and a surprising lack of compliance and enforcement. Also this week, Sarah talks with Brett Finlay, a microbiologist at the University Of British Columbia, Vancouver, about an Insight in this week’s issue that aims to connect the dots between noncommunicable diseases like heart disease, diabetes, and cancer and the microbes that live in our guts. Could these diseases actually spread through our microbiomes? This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: stu_spivack/Flickr; Music: Jeffrey Cook]




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Why some diseases come and go with the seasons, and how to develop smarter, safer chemicals

On this week’s show, host Joel Goldberg gets an update on the coronavirus pandemic from Senior Correspondent Jon Cohen. In addition, Cohen gives a rundown of his latest feature, which highlights the relationship between diseases and changing seasons—and how this relationship relates to a potential coronavirus vaccine. Also this week, from a recording made at this year’s AAAS annual meeting in Seattle, host Meagan Cantwell speaks with Alexandra Maertens, director of the Green Toxicology initiative at Johns Hopkins University, Baltimore, about the importance of incorporating nonanimal testing methods to study the adverse effects of chemicals. This week’s episode was produced with help from Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Let Ideas Compete/Flickr; Music: Jeffrey Cook] 




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How COVID-19 disease models shape shutdowns, and detecting emotions in mice

On this week’s show, Contributing Correspondent Kai Kupferschmidt talks with host Sarah Crespi about modeling coronavirus spread and the role of forecasts in national lockdowns and other pandemic policies. They also talk about the launch of a global trial of promising treatments. See all of our News coverage of the pandemic here. See all of our Research and Editorials here. Also this week, Nadine Gogolla, research group leader at the Max Planck Institute of Neurobiology, talks with Sarah about linking the facial expressions of mice to their emotional states using machine learning. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF)




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Popular mother-daughter jodis of Bollywood




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A deep learning approach to identify association of disease–gene using information of disease symptoms and protein sequences

Anal. Methods, 2020, 12,2016-2026
DOI: 10.1039/C9AY02333J, Paper
Xingyu Chen, Qixing Huang, Yang Wang, Jinlong Li, Haiyan Liu, Yun Xie, Zong Dai, Xiaoyong Zou, Zhanchao Li
Prediction of disease–gene association based on a deep convolutional neural network.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Fast determination of five chiral antipsychotic drugs using dispersive liquid–liquid microextraction combined with capillary electrophoresis

Anal. Methods, 2020, 12,2002-2008
DOI: 10.1039/C9AY02776A, Paper
Ming-Mu Hsieh, Tai-Chia Chiu, Szu-Hua Chen
This study developed a new method for the extraction, clean up, chiral separation, and determination of five pairs of phenothiazine drugs using ultrasound-assisted dispersive liquid–liquid microextraction combined with capillary electrophoresis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bio-assay of non-amidated progastrin-derived peptide (G17-Gly) using Tailor-made recombinant antibody fragment and phages display method: A biomedical analysis

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00627K, Paper
Deniz Sadighbayan, Mohammad Reza Tohid-kia, Tayebeh Mehdipour, Mohammad Hasanzadeh, Ahmad Yari Khosroushahi
In this research, four novel and sensitive immunosensor for electrochemical determination of G17-Gly were designed based on signal amplification and tailor-made recombinant antibody technology. Anti-G17-Glyantibody fragments (i.e. scFv and VL...
The content of this RSS Feed (c) The Royal Society of Chemistry