act WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2 By feeds.nature.com Published On :: 2020-05-07 Full Article
act NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas By feeds.nature.com Published On :: 2020-05-07 Full Article
act Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE) By feeds.nature.com Published On :: 2014-12-18 Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. Full Article
act Angiopoietin 2 (ANG2; ANGPT2); placental growth factor (PGF; PlGF); tissue inhibitor of metalloproteinases 3 (TIMP3) By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest inhibiting PGF could help treat hypertension. Full Article
act Epidermal growth factor receptor 1 (EGFR1; ErbB1; HER1); HER2 (EGFR2; ErbB2; neu); HER3 (EGFR3; ErbB3); VEGF By feeds.nature.com Published On :: 2014-12-18 Tumor cell and mouse studies suggest tetravalent antibodies that target four different antigens could help treat cancers resistant to HER-targeted therapies. Full Article
act Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity By feeds.nature.com Published On :: 2020-04-27 Full Article
act Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity By feeds.nature.com Published On :: 2020-05-04 Full Article
act In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states By feeds.nature.com Published On :: 2020-05-04 Full Article
act Transcription factors in ferroptotic cell death By feeds.nature.com Published On :: 2020-03-03 Full Article
act In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses By feeds.nature.com Published On :: 2020-03-31 Full Article
act Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice By feeds.nature.com Published On :: 2020-04-20 Full Article
act Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism By feeds.nature.com Published On :: 2020-04-21 Full Article
act Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation By feeds.nature.com Published On :: 2020-04-27 Full Article
act Microbiota and colorectal cancer: colibactin makes its mark By feeds.nature.com Published On :: 2020-04-21 Full Article
act Colons or semi-colons: punctuating the regional variation of intestinal microbial–immune interactions By feeds.nature.com Published On :: 2020-04-22 Full Article
act Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity By feeds.nature.com Published On :: 2020-05-07 Full Article
act Listening to the sound of a bacterium By feeds.nature.com Published On :: 2020-04-27 Full Article
act Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis By feeds.nature.com Published On :: 2020-04-28 Full Article
act Publisher Correction: Optomechanical detection of vibration modes of a single bacterium By feeds.nature.com Published On :: 2020-04-29 Full Article
act Impact of COVID-19 outbreak on spinal pathology: single center first impression By feeds.nature.com Published On :: 2020-05-05 Full Article
act A standardized patient-centered characterization of the phenotypic spectrum of <i>PCDH19</i> girls clustering epilepsy By feeds.nature.com Published On :: 2020-05-04 Full Article
act Activation and targeting of ATG8 protein lipidation By feeds.nature.com Published On :: 2020-05-05 Full Article
act Genomic characterization of patients with polycythemia vera developing resistance to hydroxyurea By feeds.nature.com Published On :: 2020-05-05 Full Article
act Impact of corticosteroid therapy on outcomes of persons with SARS-CoV-2, SARS-CoV, or MERS-CoV infection: a systematic review and meta-analysis By feeds.nature.com Published On :: 2020-05-05 Full Article
act Pomalidomide, dexamethasone, and daratumumab in relapsed refractory multiple myeloma after lenalidomide treatment By feeds.nature.com Published On :: 2020-05-06 Full Article
act Alemtuzumab plus CHOP versus CHOP in elderly patients with peripheral T-cell lymphoma: the DSHNHL2006-1B/ACT-2 trial By feeds.nature.com Published On :: 2020-05-07 Full Article
act Fixed orthodontic appliances: a practical guide By feeds.nature.com Published On :: 2020-05-08 Full Article
act NLRP3 inflammasome activity as biomarker for primary progressive multiple sclerosis By feeds.nature.com Published On :: 2020-05-04 Full Article
act Impact of the COVID-19 lockdown on basic science research in ophthalmology: the experience of a highly specialized research facility in France By feeds.nature.com Published On :: 2020-05-07 Full Article
act Julius Weitzdörfer: Managing the Impact of Nuclear Disasters By www.belfercenter.org Published On :: Dec 17, 2019 Dec 17, 2019Julius Weitzdörfer’s earliest childhood memories are the major global events of 1986—the Space Shuttle Challenger explosion and the Chernobyl disaster. Looking back, he realizes that these events must have contributed to shaping his later research interests in managing technological risks. Full Article
act The Global Pandemic Has Spawned New Forms of Activism — and They're Flourishing By feedproxy.google.com Published On :: Apr 20, 2020 Apr 20, 2020The authors have identified nearly 100 distinct methods of nonviolent action that include physical, virtual and hybrid actions. Full Article
act Carbon Taxes vs. Cap and Trade: Theory and Practice By feedproxy.google.com Published On :: Nov 24, 2019 Nov 24, 2019How do the two major approaches to carbon pricing compare on relevant dimensions, including efficiency, cost-effectiveness, and distributional equity? This paper addresses this question by drawing on theories of policy instrument choice pertaining to the attributes — or merits — of the instruments. Full Article
act Factoring Pandemic Risks into Financial Modelling By feedproxy.google.com Published On :: Apr 1, 2020 Apr 1, 2020Today’s economic crisis leaves us with an unsettling and perplexing regret. Why weren’t financial portfolios already adjusted for risks that stem from health events such as pandemics? After all, financial portfolios are adjusted for liquidity risks, market risks, credit risks, and even operational and political risks. Full Article
act The Global Pandemic Has Spawned New Forms of Activism — and They're Flourishing By feedproxy.google.com Published On :: Apr 20, 2020 Apr 20, 2020The authors have identified nearly 100 distinct methods of nonviolent action that include physical, virtual and hybrid actions. Full Article
act The Global Pandemic Has Spawned New Forms of Activism — and They're Flourishing By feedproxy.google.com Published On :: Apr 20, 2020 Apr 20, 2020The authors have identified nearly 100 distinct methods of nonviolent action that include physical, virtual and hybrid actions. Full Article
act Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers By feeds.nature.com Published On :: 2020-04-27 Full Article
act Enhancer–promoter interactions and transcription By feeds.nature.com Published On :: 2020-05-06 Full Article
act Mitigating osteonecrosis of the jaw (ONJ) through preventive dental care and understanding of risk factors By feeds.nature.com Published On :: 2020-03-11 Full Article
act Controversial practice of rewarding for publications in national journals By eprints.rclis.org Published On :: Wed, 29 Apr 2020 13:29:46 +0200 Nazarovets, Serhii Controversial practice of rewarding for publications in national journals., 2020 [Preprint] Full Article
act Impact of Covid-19 on the media system. Communicative and democratic consequences of news consumption during the outbreak // Impacto del Covid-19 en el sistema de medios. Consecuencias comunicativas y democráticas del consumo de noticias durante el By eprints.rclis.org Published On :: Sat, 09 May 2020 09:35:47 +0200 Casero-Ripollés, Andreu Impact of Covid-19 on the media system. Communicative and democratic consequences of news consumption during the outbreak // Impacto del Covid-19 en el sistema de medios. Consecuencias comunicativas y democráticas del consumo de noticias durante el brote. El profesional de la información, 2020, vol. 29, n. 2. [Journal article (Unpaginated)] Full Article
act Carbon Taxes vs. Cap and Trade: Theory and Practice By feedproxy.google.com Published On :: Nov 24, 2019 Nov 24, 2019How do the two major approaches to carbon pricing compare on relevant dimensions, including efficiency, cost-effectiveness, and distributional equity? This paper addresses this question by drawing on theories of policy instrument choice pertaining to the attributes — or merits — of the instruments. Full Article
act Factoring Pandemic Risks into Financial Modelling By feedproxy.google.com Published On :: Apr 1, 2020 Apr 1, 2020Today’s economic crisis leaves us with an unsettling and perplexing regret. Why weren’t financial portfolios already adjusted for risks that stem from health events such as pandemics? After all, financial portfolios are adjusted for liquidity risks, market risks, credit risks, and even operational and political risks. Full Article
act The Global Pandemic Has Spawned New Forms of Activism — and They're Flourishing By feedproxy.google.com Published On :: Apr 20, 2020 Apr 20, 2020The authors have identified nearly 100 distinct methods of nonviolent action that include physical, virtual and hybrid actions. Full Article
act Assessing Progress on Nuclear Security Action Plans By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Participants at the final Nuclear Security Summit in 2016 agreed on “action plans” for initiatives they would support by five international organizations and groups—the International Atomic Energy Agency, the Global Initiative to Combat Nuclear Terrorism, INTERPOL, the United Nations, and the Global Partnership Against the Spread of Weapons and Materials of Destruction. These institutions were supposed to play key roles in bolstering ongoing nuclear security cooperation after the summit process ended. The action plans were modest documents, largely endorsing activities already underway, and there have been mixed results in implementing them. To date, these organizations have not filled any substantial part of the role once played by the nuclear security summits. Full Article
act Washington Should Take Action on AI or Stay Out of the Way By feedproxy.google.com Published On :: Mar 19, 2020 Mar 19, 2020Federal and local regulations are part of the solution to tough issues related to Artificial Intelligence, writes K. Gretchen Greene, but no regulatory approach on its own can fully answer these questions today. "Finding answers will require significant investments in research and development, collaboration, negotiation, and experimentation, deep and careful thought across many fields and leadership at all levels, across and between governments. The U.S. federal government is well positioned to lead, but if it won't, it should at least stay out of the way." Full Article
act How to Avoid a Pandemic Patriot Act By feedproxy.google.com Published On :: Apr 21, 2020 Apr 21, 2020The last time the United States faced a big, hard-to-track threat, we ended up with the Patriot Act and a mass-surveillance program that still rankles. This time, how do we use technology to combat the novel coronavirus without creating elements of a police state? Full Article
act Why Matter Matters: How Technology Characteristics Shape the Strategic Framing of Technologies By feedproxy.google.com Published On :: Nov 13, 2019 Nov 13, 2019The authors investigate how the executives of the two largest research institutes for photovoltaic technologies — the National Renewable Energy Laboratory (NREL) in Golden, USA and the Fraunhofer Institute for Solar Energy Systems (Fraunhofer ISE) in Freiburg, Germany — have made use of public framing to secure funding and shape the technological development of solar photovoltaic (PV) technologies. The article shows that the executives used four framing dimensions (potential, prospect, performance, and progress) and three framing tactics (conclusion, conditioning, and concession), and that the choice of dimensions and tactics is tightly coupled to the characteristics of the specific technologies pursued by the research institutes. Full Article