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Experimental cancer cell therapies have nearly doubled in six months

A new report from the Cancer Research Institute highlights the U.S. and China as cell therapy leaders




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The difficult search for the right recipe in cancer immunotherapy

With so many ingredients on hand, can the oncology community figure out how to sensibly and efficiently combine checkpoint inhibitors with other drugs?




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U.K. pilots carbon capture technology




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Chemistry in Pictures: Lapus lattice




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SK Capital buys additives maker SI Group

Private equity firm aims to assemble a specialty additives powerhouse




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Inorganic Nanoscience Award to Dmitri Talapin




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Arsenal Capital buys adhesives makers




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BridgeBio launches CoA Therapeutics to treat a rare neurodegenerative disease

The startup is developing allosteric activators to increase levels of the vital metabolic molecule coenzyme A in pantothenate kinase-associated neurodegeneration




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Periodic Graphics: The chemistry of slime

Chemical educator and Compound Interest blogger Andy Brunning wrings all the molecular details out of the popular goo




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ACS Nigeria Chapter hosts symposium in Uyo




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Alexion partners with Complement Pharma on neurodegenerative therapy




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Chemists synthesize Saturn-shaped molecule

Flat, macrocyclic host captures fullerene guest with CH–π interactions




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Synthetic biology could enable bioweapons development

A new National Academies report names and classifies the kinds of biological weapons that could emerge from techniques like CRISPR gene editing and DNA synthesis




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Sarepta’s Duchenne gene therapy shows promise in small study

The early peek at data from a Phase I/II study excited families, physicians, and investors 




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Oil and gas wastewater is a cheap fix for road dust but comes at a toxic cost

Treating roads with the wastewater may pollute the environment with radium and oil and gas compounds




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Novacap to enter the U.S. by acquiring PCI Synthesis

French pharmaceutical services firm is latest to move into the U.S.




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When trapped, water becomes less polar

In confined spaces, water’s dielectric constant drops dramatically, according to new measurements




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Start-up Olaplex triumphs over L’Oréal in court case




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Oil and gas wastewater is a cheap fix for road dust, but it comes at a toxic cost

Treating roads with wastewater may pollute the environment with radium




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Gene therapy start-up Freeline Therapeutics raises $116 million




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BridgeBio licenses compounds from NeuroVive and launches Fortify Therapeutics




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AbbVie invests in switchable CAR-T therapies for cancer

The drug company is partnering with Calibr to develop universal CAR T-cells directed to different tumors via antibody switches




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Changes on tap at U.S. Chemical Safety Board

Chair departs, investigators leave, staff fears changing mission




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Celgene partners with Skyhawk Therapeutics to drug RNA with small molecules

Skyhawk will receive $60 million up front to develop drug candidates that target RNA in neurological diseases




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Apeel coating extends avocado shelf life




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AbbVie invests in switchable CAR-T therapies for cancer

The drug company is partnering with Calibr to develop universal CAR T cells directed to different tumors via antibody switches




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BASF taps Citrine for artificial intelligence




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Honeywell and Chemours ask U.S. Supreme Court to hear appeal in HFC case




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Errors in C&EN graphic reveal widespread misconceptions about slime chemistry

Multiple sources, including journal articles and chemical catalogs, get the borate bonding and reactivity wrong




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Call for papers for fluorine conference




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Sinochem, ChemChina merger appears likely




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Lundbeck taps former Millennium chief as CEO




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Carisma Therapeutics raises $53 million for CAR-T alternative using macrophages




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Leading the chemical safety landscape




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Periodic Graphics: Lava and volcanic gases

Chemical educator and Compound Interest blogger Andy Brunning probes the molecular makeup of the molten rock and gases spewed by volcanoes




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Noninvasive chemical approach controls deep region of the brain in mice

In mice, surgery-free technique inhibits region implicated in memory formation




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Compass Therapeutics debuts with $132 million in funding




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ACS Council and its role in shaping the society




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Changes on tap at U.S. Chemical Safety Board

Chair departs, investigators leave, staff fears changing mission




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Graphene-based device enables active thermal camouflage

Smart, flexible skins measure and adapt to ambient temperatures




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Fetal gene therapy could treat genetic diseases in the womb

Researchers are working to fix genetic conditions like Gaucher disease before birth by testing experimental therapies on fetal animals




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HotSpot Therapeutics debuts with $45 million to pursue allosteric inhibitors

The company claims its technology will allow it to access previously undruggable targets




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Raptor report: Berkeley birds and rodent wranglers




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Graphene-based device enables active thermal camouflage

Smart, flexible skins measure and adapt to ambient temperatures




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HotSpot Therapeutics debuts with $45 million to pursue allosteric inhibitors

The company claims its technology will allow it to access previously undruggable targets




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Chemistry in Pictures: Flag column chromatography




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Paper describing piperlongumine anticancer activity retracted

Some coauthors dissent from withdrawal of report, for which key findings have been independently confirmed




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Chemical toxicity assessments by U.S. EPA to be reshaped, if bill passes

Congressional committee votes to give industry and other agencies greater input and to shift responsibility for IRIS program from research office




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GSK, 23andMe to apply personal genetics to drug discovery

New partnership is part of GSK’s R&D face-lift, which includes an increased focus on immune system targets




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PTC buys gene-therapy-focused Agilis