Latest dis news

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[ASAP] Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology

By feedproxy.google.com
Published On :: Tue, 28 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.9b01336

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[ASAP] Computational Chemistry on a Budget: Supporting Drug Discovery with Limited Resources<subtitle>Miniperspective</subtitle>

By feedproxy.google.com
Published On :: Fri, 01 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.9b02126

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[ASAP] Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity

By feedproxy.google.com
Published On :: Wed, 06 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00245

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[ASAP] Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue

By feedproxy.google.com
Published On :: Thu, 07 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00337

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[ASAP] Discovery of <italic toggle="yes">N</italic>-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1<italic toggle="yes">H</italic>-pyrrolo[2,3-<italic toggle=&q

By feedproxy.google.com
Published On :: Thu, 07 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00628

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[ASAP] Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor

By feedproxy.google.com
Published On :: Thu, 07 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00082

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[ASAP] Discovery and Optimization of Glucose Uptake Inhibitors

By feedproxy.google.com
Published On :: Fri, 08 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.9b02153

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[ASAP] Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria

By feedproxy.google.com
Published On :: Mon, 30 Mar 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00005

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[ASAP] Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma

By feedproxy.google.com
Published On :: Mon, 30 Mar 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.9b00601

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[ASAP] Assembling Pharma Resources to Tackle Diseases of Underserved Populations

By feedproxy.google.com
Published On :: Wed, 08 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00051

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[ASAP] Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor

By feedproxy.google.com
Published On :: Thu, 09 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.9b00681

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[ASAP] Discovery of BMS-986251: A Clinically Viable, Potent, and Selective ROR?t Inverse Agonist

By feedproxy.google.com
Published On :: Fri, 10 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00063

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[ASAP] Discovery of a Potent Dual Inhibitor of Wild-Type and Mutant Respiratory Syncytial Virus Fusion Proteins

By feedproxy.google.com
Published On :: Wed, 15 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00008

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[ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif

By feedproxy.google.com
Published On :: Wed, 15 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00095

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[ASAP] Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor

By feedproxy.google.com
Published On :: Mon, 27 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00155

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[ASAP] PROTAC Compounds Targeting a-Synuclein Protein for Treating Neurogenerative Disorders: Alzheimer’s and Parkinson’s Diseases

By feedproxy.google.com
Published On :: Tue, 28 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00192

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[ASAP] Discovery of RO7185876, a Highly Potent ?-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer’s Disease

By feedproxy.google.com
Published On :: Fri, 01 May 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00109

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[ASAP] Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors

By feedproxy.google.com
Published On :: Fri, 01 May 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00025

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[ASAP] Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793

By feedproxy.google.com
Published On :: Tue, 05 May 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00085

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[ASAP] De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits

By feedproxy.google.com
Published On :: Tue, 05 May 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00022

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Herbst im paradies: The autumn of paradise / Jean-Luc Mylayne

By library.mit.edu
Published On :: Sun, 23 Feb 2020 06:00:02 EST

Rotch Library - TR729.B5 H47 2018

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Discordo ergo sum: Renate Bertlmann / curator, Felicitas Thun-Hohenstein

By library.mit.edu
Published On :: Sun, 23 Feb 2020 06:00:02 EST

Rotch Library - N6488.I8 V433 2019 A9

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Inside Tangier: houses & gardens / Nicolò Castellini Baldissera ; photography, Guido Taroni ; foreword, Hamish Bowles

By library.mit.edu
Published On :: Sun, 22 Mar 2020 06:00:01 EDT

Rotch Library - NK2087.75.A1 B35 2019

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À l'orientale: collecting, displaying and appropriating Islamic art and architecture in the 19th and early 20th centuries / edited by Francine Giese, Mercedes Volait, Ariane Varela Braga

By library.mit.edu
Published On :: Sun, 12 Apr 2020 06:00:01 EDT

Rotch Library - N6260.A12 2020

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Proceedings of the 2nd International and Interdisciplinary Conference on Image and Imagination: IMG 2019 / Enrico Cicalò, editor

By library.mit.edu
Published On :: Sun, 26 Apr 2020 06:00:01 EDT

Online Resource

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Museums of language and the display of intangible cultural heritage / edited by Margaret J-M. Sönmez, Maia Wellington Gahtan, and Nadia Cannata.

By darius.uleth.ca
Published On ::

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Los disfraces: la obra mestiza de Carlos Fuentes / Georgina García Gutiérrez

By library.mit.edu
Published On :: Sun, 7 Oct 2018 06:29:04 EDT

Online Resource

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Crítica textual: un enfoque multidisciplinario para la edición de textos / editores, Belem Clark de Lara [and others]

By library.mit.edu
Published On :: Sun, 25 Nov 2018 06:36:04 EST

Online Resource

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Discurso de la novela española contemporanea / Max Aub

By library.mit.edu
Published On :: Sun, 30 Dec 2018 09:30:08 EST

Online Resource

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Disabled bodies in early modern Spanish literature: prostitutes, aging women and saints / Encarnación Juárez-Almendros

By library.mit.edu
Published On :: Sun, 17 Feb 2019 09:27:58 EST

Online Resource

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¿Discapacidad: literatura, teatro y cine hispánicos vistos desde los disability studies / Susanne Hartwig, Julio Enrique Checa Puerta

By library.mit.edu
Published On :: Sun, 10 Mar 2019 09:29:48 EDT

Online Resource

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New Handout on Services for Users with Disabilities

By westinfopoint.blogspot.com
Published On :: Thu, 28 Aug 2008 14:22:00 +0000

Stacey Ewing created a wonderful new handout on types of adaptive services we offer users here in Library West. If you have any free moments the next time you staff the InfoPoint, I encourage you to take a look at this guide.

ada
handouts

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Examining Opioid Use Among Applicants for Disability Insurance

By www.mathematica.org
Published On :: Thu, 05 Dec 2019 14:13:14 Z

On this episode of On the Evidence, April Yanyuan Wu, a researcher at Mathematica, discusses a project that used supervised machine learning to estimate prescription opioid use among applicants for Social Security Disability Insurance.

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Lessons from Scaling a Customized Employment Program for Workers with Disabilities

By www.mathematica.org
Published On :: Wed, 26 Feb 2020 15:07:00 Z

In this episode of On the Evidence, Shane Kanady of SourceAmerica and Noelle Denny-Brown of Mathematica discuss findings from an evaluation of the Pathways to Careers program, which provides customized employment services to job seekers with significant disabilities.

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Improving Alternative Payment Models Through Program Monitoring: Observing the Impacts on Patients Living in Disadvantaged Neighborhoods

By www.mathematica.org
Published On :: Thu, 27 Feb 2020 05:00:00 Z

We believe the value of program monitoring is in iteration. By combining live program administrative data with vetted measures of socioeconomic status, we help clients and stakeholders understand alternative payment models and make important improvements.

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Russia, BRICS, and the disruption of global order / Rachel S. Salzman

By library.mit.edu
Published On :: Sun, 7 Jul 2019 09:21:52 EDT

Dewey Library - JZ1616.A57 B757 2019

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Cross-disciplinary perspectives on regional and global security / Paweł Frankowski, Artur Gruszczak, editors

By library.mit.edu
Published On :: Sun, 14 Jul 2019 09:32:17 EDT

Online Resource

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Multipolarity: the promise of disharmony / Peter W. Schulze (ed.)

By library.mit.edu
Published On :: Sun, 4 Aug 2019 10:22:43 EDT

Dewey Library - JZ1305.M858 2018

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Imagining disarmament, enchanting international relations / Matthew Breay Bolton

By library.mit.edu
Published On :: Sun, 12 Jan 2020 08:36:28 EST

Online Resource

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Global activism and humanitarian disarmament / Matthew Breay Bolton, Sarah Njeri, Taylor Benjamin-Britton, editors

By library.mit.edu
Published On :: Sun, 12 Jan 2020 08:36:28 EST

Online Resource

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Hegemonía y democracia en disputa: Trump y la geopolítica del neoconservadurismo / Marco A. Gandásegui (hijo), Jaime Antonio Preciado Coronado (Coordinadores)

By library.mit.edu
Published On :: Sun, 9 Feb 2020 07:48:42 EST

Online Resource

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The influence of civil society on Japanese nuclear disarmament policy / Kazuhiro Tobisawa

By library.mit.edu
Published On :: Sun, 23 Feb 2020 09:36:00 EST

Dewey Library - JZ5675.T62 2018

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Pensar el fenómeno narco: el narcotráfico en los discursos audiovisuales (2010-2015) / Esteban Mizrahi [and 6 others]

By library.mit.edu
Published On :: Sun, 15 Sep 2019 07:36:30 EDT

Online Resource

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The ride of a lifetime: lessons learned from 15 years as CEO of the Walt Disney Company / Robert Iger

By library.mit.edu
Published On :: Sun, 2 Feb 2020 06:51:59 EST

Dewey Library - PN1998.3.I28 A3 2019

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The queens of animation: the untold story of the women who transformed the world of Disney and made cinematic history / Nathalia Holt

By library.mit.edu
Published On :: Sun, 9 Feb 2020 06:39:20 EST

Dewey Library - PN1999.W27 H59 2019

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On the screen: displaying the moving image, 1926-1942 / Ariel Rogers

By library.mit.edu
Published On :: Sun, 9 Feb 2020 06:39:20 EST

Online Resource

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Film art: an introduction / David Bordwell, University of Wisconsin--Madison, Kristin Thompson, University of Wisconsin--Madison., Jeff Smith, University of Wisconsin--Madison

By library.mit.edu
Published On :: Sun, 15 Mar 2020 06:46:24 EDT

Dewey Library - PN1995.B617 2019

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Rediscovering Korean cinema / edited by Sangjoon Lee

By library.mit.edu
Published On :: Sun, 26 Apr 2020 07:06:33 EDT

Dewey Library - PN1993.5.K6 R43 2019

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Breaking Down Work Barriers for People with Disabilities: Opportunities for Employers

By www.mathematica.org
Published On :: Thu, 01 Mar 2018 18:00:00 Z

Mathematica’s Center for Studying Disability Policy (CSDP) hosted a webinar to examine these issues from the employer perspective. Panelists discussed: (1) actions employers can take to better accommodate employees with disabilities; (2) feedback from employer interviews about the challenges associated with recruiting and retaining workers with disabilities; and (3) findings from the National Employment and Disability Survey, recently released by the Kessler Foundation.

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Disability Research Consortium Annual Meeting 2018

By www.mathematica.org
Published On :: Wed, 01 Aug 2018 12:00:00 Z

This conference highlighted the DRC’s latest research findings and their implications for the future of state and federal disability policies and programs.