tool iOS Messaging Tools By packetstormsecurity.com Published On :: Wed, 07 Aug 2019 23:44:28 GMT This repository contains several tools Project Zero uses to test iPhone messaging. It includes SmsSimulator: an SMS simulator for iPhone, iMessage: tools for sending and dumping iMessage messages, and imapiness: a fuzzer for IMAP clients. See the directory for each tool for further instructions and contact information. This is not an officially supported Google product. These tools were released and presented at BlackHat USA 2019. Full Article
tool URLCrazy Domain Name Typo Tool 0.7.1 By packetstormsecurity.com Published On :: Fri, 24 Apr 2020 18:22:22 GMT URLCrazy is a tool that can generate and test domain typos and variations to detect and perform typo squatting, URL hijacking, phishing, and corporate espionage. It generates 15 types of domain variants, knows over 8000 common misspellings, supports multiple keyboard layouts, can check if a typo is a valid domain, tests if domain typos are in use, and estimates the popularity of a typo. Full Article
tool SQLMAP - Automatic SQL Injection Tool 1.4.5 By packetstormsecurity.com Published On :: Mon, 04 May 2020 17:30:13 GMT sqlmap is an open source command-line automatic SQL injection tool. Its goal is to detect and take advantage of SQL injection vulnerabilities in web applications. Once it detects one or more SQL injections on the target host, the user can choose among a variety of options to perform an extensive back-end database management system fingerprint, retrieve DBMS session user and database, enumerate users, password hashes, privileges, databases, dump entire or user's specified DBMS tables/columns, run his own SQL statement, read or write either text or binary files on the file system, execute arbitrary commands on the operating system, establish an out-of-band stateful connection between the attacker box and the database server via Metasploit payload stager, database stored procedure buffer overflow exploitation or SMB relay attack and more. Full Article
tool ChronIC RF Hacking Tool By packetstormsecurity.com Published On :: Tue, 12 Mar 2013 18:22:22 GMT ChronIC is the Chronos Integrated Commander, a wearable Sub-GHz RF hacking tool. Written in python. Full Article
tool Wi-fEye Wireless Pentesting Tool 1.0 Beta By packetstormsecurity.com Published On :: Mon, 26 Aug 2013 14:43:33 GMT Wi-fEye is designed to help with network penetration testing. It allows the user to perform a number of powerful attack automatically including WEP/WPA cracking, session hijacking and more. Full Article
tool HWK Wireless Auditing Tool 0.4 By packetstormsecurity.com Published On :: Fri, 18 Oct 2013 01:30:01 GMT hwk is an easy-to-use wireless authentication and de-authentication tool. Furthermore, it also supports probe response fuzzing, beacon injection flooding, antenna alignment and various injection testing modes. Information gathering is selected by default and shows the incoming traffic indicating the packet types. Full Article
tool Aircrack-ng Wireless Network Tools 1.2 Beta 3 By packetstormsecurity.com Published On :: Tue, 01 Apr 2014 23:02:22 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool WifiPhisher Phishing Tool By packetstormsecurity.com Published On :: Sun, 04 Jan 2015 23:33:33 GMT Wifiphisher is a security tool that mounts fast automated phishing attacks against WPA networks in order to obtain the secret passphrase. It is a social engineering attack that unlike other methods it does not include any brute forcing. It is an easy way for obtaining WPA credentials. Full Article
tool Aircrack-ng Wireless Network Tools 1.2 RC2 By packetstormsecurity.com Published On :: Fri, 10 Apr 2015 22:05:23 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool Aircrack-ng Wireless Network Tools 1.2 RC3 By packetstormsecurity.com Published On :: Sun, 22 Nov 2015 15:55:55 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool Aircrack-ng Wireless Network Tools 1.2 RC4 By packetstormsecurity.com Published On :: Tue, 16 Feb 2016 17:29:48 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool Aircrack-ng Wireless Network Tools 1.2 RC5 By packetstormsecurity.com Published On :: Wed, 11 Apr 2018 16:29:30 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool Aircrack-ng Wireless Network Tools 1.2 By packetstormsecurity.com Published On :: Mon, 16 Apr 2018 18:22:22 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool Aircrack-ng Wireless Network Tools 1.3 By packetstormsecurity.com Published On :: Wed, 11 Jul 2018 02:52:27 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool Aircrack-ng Wireless Network Tools 1.4 By packetstormsecurity.com Published On :: Mon, 01 Oct 2018 17:53:31 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool Aircrack-ng Wireless Network Tools 1.6 By packetstormsecurity.com Published On :: Mon, 27 Jan 2020 23:08:40 GMT aircrack-ng is a set of tools for auditing wireless networks. It's an enhanced/reborn version of aircrack. It consists of airodump (an 802.11 packet capture program), aireplay (an 802.11 packet injection program), aircrack (static WEP and WPA-PSK cracking), airdecap (decrypts WEP/WPA capture files), and some tools to handle capture files (merge, convert, etc.). Full Article
tool Htcap Analysis Tool 1.1.0 By packetstormsecurity.com Published On :: Wed, 28 Nov 2018 18:01:38 GMT Htcap is a web application analysis tool for detecting communications between javascript and the server. It crawls the target application and maps ajax calls, dynamically inserted scripts, websockets calls, dynamically loaded resources and some interesting elements. The generated report is meant to be a good starting point for a manual web application security audit. Htcap is written in python and uses phantomjs to load pages injecting a probe that analyzes javascript behaviour. Once injected, the probe, overrides native javascript methods in order to intercept communications and DOM changes. It also simulates user interaction by firing all attached events and by filling html inputs. Full Article
tool A Private Spy Was Caught Using A Hacking Tool To Target Their Crush By packetstormsecurity.com Published On :: Fri, 01 May 2020 13:36:43 GMT Full Article headline hacker privacy phone israel spyware
tool 30+ Web Tools and Services Reviewed For You By feedproxy.google.com Published On :: Fri, 08 May 2020 18:04:55 PDT The market is crowded with tens of thousands of web tools and services, every day a new web product is being launched. It is super-simple and anybody can do it. How is that possible? Because technology advanced in an unimaginable way and now everything is possible by using the right web tools and services. Launching a webshop or blog can be done in a couple of minutes. Creating a gorgeous logo or company branding is not taking more than a few minutes by using AI drive logo platforms. Same platforms are also available for building websites. Anything you want can be done with small costs or even for free. Full Article Design Services sponsor Web Development Web Tools
tool MHK risk assessment tool set for demonstration in London this month By feedproxy.google.com Published On :: 2015-11-18T16:13:00Z Offshore Renewable Energy (ORE) Catapult and consultancy firm Frazer-Nash, both based in the UK, will perform a live demonstration of their marine hydrokinetics (MHK) energy project risk assessment tool during the International Tidal Energy Summit pre-conference risk and reliability workshop in London on Nov. 23. Full Article
tool Spotlight on Public Events: Microfinance as a Tool for Community Development By feedproxy.google.com Published On :: Thu, 07 Apr 2011 08:35:28 +0000 Spotlight on Public Events: Microfinance as a Tool for Community Development EWC Changing Faces Women’s Leadership Program participant Kalpana Sankar, CEO of Hand in Hand in Tamil Nadu (India), speaking on microfinance initiatives. Kathleen Stack, Vice President of Freedom from Hunger and a participant in EWC’s 2009 Changing Faces Women’s Leadership Program, speaking on her NGO’s microfinance projects. Full Article
tool Tracking apps useful tool, but raise privacy fears By www.shanghaidaily.com Published On :: Wed, 06 May 2020 00:00:00 +0800 As governments around the world consider how to monitor novel coronavirus outbreaks while reopening their societies, many are starting to bet on smartphone apps to help stem the pandemic. Full Article World
tool EWC Receives $458,000 to Improve HIV Estimation and Projection Tools By feedproxy.google.com Published On :: Fri, 04 May 2012 23:55:11 +0000 HONOLULU (May 4, 2012) – The East-West Center (EWC) has been awarded a contract for $458,276 from the Joint United Nations Programme on HIV/AIDS (UNAIDS) to provide technical and financial support for the development and refinement of HIV/AIDS Incidence Estimation in the Spectrum software under the guidance of the UNAIDS Reference Group on HIV/AIDS Estimates, Modeling and Projection. Spectrum is a suite of policy models that provide policymakers with analytical tools to support decision making processes. Full Article
tool EWC and US-ASEAN Business Council Launch 'ASEAN Matters for America" Online Tool and Publication By feedproxy.google.com Published On :: Thu, 10 Apr 2014 20:46:25 +0000 WASHINGTON, D.C. (April 10, 2014) – At an event on Capitol Hill yesterday, the US-ASEAN Business Council and the East West Center launched a new “ASEAN Matters for America” publication and online tool that outlines the essential role ASEAN plays in American economic prosperity. Senate East Asia and Pacific Affairs Subcommittee Chairman Ben Cardin and House Foreign Affairs Committee Chairman Ed Royce spoke at the launch event, which also included a discussion panel with leaders from the Southeast Asia business, media, analysis and diplomatic communities. Full Article
tool Department of Environmental Affairs | Requirement to submit a report generated by the national web based environmental screening tool By www.eversheds.com Published On :: 2019-08-30 Introduction On 5 July 2019, the Minister of Environment, Forestry and Fisheries, Barbara Dallas Creecy, published a notice requiring that when submitting an application for environmental authorisation in terms of regulation 19 and regulation 21 of ... Full Article
tool Covid-19: Feeling sick? Use digital self-assessment tool HealthCheck By Published On :: Fri, 08 May 2020 12:25:00 GMT Enables early detection, mapping and management of coronavirus using USSD and official government WhatsApp service, Covid Connect Full Article
tool The tools that prepare Israel for the future war By www.jpost.com Published On :: Sat, 09 May 2020 11:14:36 GMT How multidimensional joint operations, lessons from past wars and new technologies have transformed Israel’s army, navy and air force. Full Article Gaza Hamas Hezbollah IAF IDF israeli navy
tool In Indonesia, a new tool is being used to fight child marriage -- by Claudia Buentjen, Kate Walton By blogs.adb.org Published On :: Thu, 21 Nov 2019 08:45:23 +0800 Local officials can now find information from all sectors, such as health, education, women’s empowerment, child protection, and human rights and law, to help them address child and teen marriage in their area. Full Article
tool COVID-19 is an opportunity to re-tool the health sector’s energy supply -- by Susumu Yoneoka, Dan Millison By blogs.adb.org Published On :: Thu, 23 Apr 2020 16:49:50 +0800 The pandemic reinforces the need for reliable energy services to support healthcare. Clean, renewable power is a good place to start. Full Article
tool Microchip Simplifies Functional Safety Requirements with MPLAB TÜV SÜD-certified Tools By www.microchip.com Published On :: 1/15/2020 8:50:00 AM Microchip Simplifies Functional Safety Requirements with MPLAB TÜV SÜD-certified Tools Full Article
tool 16-Bit Language Tools Libraries By ww1.microchip.com Published On :: 1/29/2020 8:39:39 PM 16-Bit Language Tools Libraries Full Article
tool IS206X Introduction to DSP Configuration tool and AEC Tuning Guide Application Note By www.microchip.com Published On :: 4/13/2020 6:24:11 PM IS206X Introduction to DSP Configuration tool and AEC Tuning Guide Application Note Full Article
tool Ancient shark used its teeth like the blade of a power tool By www.newscientist.com Published On :: Thu, 16 Jan 2020 16:36:37 +0000 The extinct shark Edestus used its teeth like saw blades, sliding them past each other like a power tool to slice through the soft flesh of its prey Full Article
tool Thousands of Denisovan tools reveal their Stone Age technologies By www.newscientist.com Published On :: Wed, 26 Feb 2020 08:00:31 +0000 A cache of Denisovan tools shows how these extinct humans moved from using sharp stone flakes 150,000 years ago to stone blades and chisels around 60,000 years ago Full Article
tool Homo erectus used two different kinds of stone tools By www.newscientist.com Published On :: Thu, 05 Mar 2020 16:11:19 +0000 Skull fragments from Homo erectus found alongside stone tools in Ethiopia suggest the ancient hominin used more tool technology than we thought Full Article
tool Library LinkOut using Outside Tool By www.nlm.nih.gov Published On :: Mon, 08 Jul 2019 09:00:00 EST Library icons now appear in PubMed Labs for libraries participating in the Library LinkOut using Outside Tool service. Full Article
tool Mindfulness a Powerful Tool for Aging By www.medicinenet.com Published On :: Fri, 3 Apr 2020 00:00:00 PDT Title: Mindfulness a Powerful Tool for AgingCategory: Health NewsCreated: 4/2/2020 12:00:00 AMLast Editorial Review: 4/3/2020 12:00:00 AM Full Article
tool Apparent Cause Analysis: A Safety Tool By pediatrics.aappublications.org Published On :: 2020-05-01T01:00:46-07:00 Causal analysis is a core function of safety programs. Although established protocols exist for conducting root cause analysis for serious safety events, there is limited guidance for apparent cause analysis (ACA) in health care. At our institution, through a novel facilitated ACA approach, we aim to improve safety culture and provide a clear approach to address precursor safety events and near-miss safety events. We define facilitated ACA as limited investigation (scope and duration) of a safety event that resulted in little to no harm. These investigations require fewer resources and focus on preventive strategies. Our facilitated ACA model, with an operational algorithm and structured process, was developed and implemented at our tertiary-care, freestanding, urban pediatric hospital in 2018. Sixty-four ACAs were completed, and 83% were identified with the algorithm. Process measures, including time from event reporting to ACA launch (median 3 days; interquartile range 2–6 days), are tracked. Patient safety consultants averaged 5 hours to complete a facilitated ACA. A median of 3 disciplines or departments participated in each facilitated ACA. Through an iterative process, we implemented a structured process for facilitated ACA, and the model’s strength includes (1) right event, (2) right team, (3) right analysis, and (4) right action plans. This novel facilitated ACA model may support organizational cause analysis and improve safety culture with higher-reliability processes. Full Article
tool A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues [Neuroscience] By www.pnas.org Published On :: 2020-05-05T10:31:24-07:00 Transcription factors (TFs) enact precise regulation of gene expression through site-specific, genome-wide binding. Common methods for TF-occupancy profiling, such as chromatin immunoprecipitation, are limited by requirement of TF-specific antibodies and provide only end-point snapshots of TF binding. Alternatively, TF-tagging techniques, in which a TF is fused to a DNA-modifying enzyme... Full Article
tool A Simple Clinical Tool for Stratifying Risk of Clinically Significant CKD after Nephrectomy: Development and Multinational Validation By jasn.asnjournals.org Published On :: 2020-04-30T10:00:30-07:00 Background Clinically significant CKD following surgery for kidney cancer is associated with increased morbidity and mortality, but identifying patients at increased CKD risk remains difficult. Simple methods to stratify risk of clinically significant CKD after nephrectomy are needed. Methods To develop a tool for stratifying patients’ risk of CKD arising after surgery for kidney cancer, we tested models in a population-based cohort of 699 patients with kidney cancer in Queensland, Australia (2012–2013). We validated these models in a population-based cohort of 423 patients from Victoria, Australia, and in patient cohorts from single centers in Queensland, Scotland, and England. Eligible patients had two functioning kidneys and a preoperative eGFR ≥60 ml/min per 1.73 m2. The main outcome was incident eGFR <45 ml/min per 1.73 m2 at 12 months postnephrectomy. We used prespecified predictors—age ≥65 years old, diabetes mellitus, preoperative eGFR, and nephrectomy type (partial/radical)—to fit logistic regression models and grouped patients according to degree of risk of clinically significant CKD (negligible, low, moderate, or high risk). Results Absolute risks of stage 3b or higher CKD were <2%, 3% to 14%, 21% to 26%, and 46% to 69% across the four strata of negligible, low, moderate, and high risk, respectively. The negative predictive value of the negligible risk category was 98.9% for clinically significant CKD. The c statistic for this score ranged from 0.84 to 0.88 across derivation and validation cohorts. Conclusions Our simple scoring system can reproducibly stratify postnephrectomy CKD risk on the basis of readily available parameters. This clinical tool’s quantitative assessment of CKD risk may be weighed against other considerations when planning management of kidney tumors and help inform shared decision making between clinicians and patients. Full Article
tool RNAconTest: comparing tools for noncoding RNA multiple sequence alignment based on structural consistency [BIOINFORMATICS] By rnajournal.cshlp.org Published On :: 2020-04-16T06:30:22-07:00 The importance of noncoding RNA sequences has become increasingly clear over the past decade. New RNA families are often detected and analyzed using comparative methods based on multiple sequence alignments. Accordingly, a number of programs have been developed for aligning and deriving secondary structures from sets of RNA sequences. Yet, the best tools for these tasks remain unclear because existing benchmarks contain too few sequences belonging to only a small number of RNA families. RNAconTest (RNA consistency test) is a new benchmarking approach relying on the observation that secondary structure is often conserved across highly divergent RNA sequences from the same family. RNAconTest scores multiple sequence alignments based on the level of consistency among known secondary structures belonging to reference sequences in their output alignment. Similarly, consensus secondary structure predictions are scored according to their agreement with one or more known structures in a family. Comparing the performance of 10 popular alignment programs using RNAconTest revealed that DAFS, DECIPHER, LocARNA, and MAFFT created the most structurally consistent alignments. The best consensus secondary structure predictions were generated by DAFS and LocARNA (via RNAalifold). Many of the methods specific to noncoding RNAs exhibited poor scalability as the number or length of input sequences increased, and several programs displayed substantial declines in score as more sequences were aligned. Overall, RNAconTest provides a means of testing and improving tools for comparative RNA analysis, as well as highlighting the best available approaches. RNAconTest is available from the DECIPHER website (http://DECIPHER.codes/Downloads.html). Full Article
tool Decision tree as a tool for the management of coastal aquifers of limited saturated thickness By qjegh.lyellcollection.org Published On :: 2020-05-01T00:46:18-07:00 In this paper, a decision tree is presented, constructed on the basis of hydrogeological characteristics (water table depth, freshwater thickness, surface area required and distance between wells), to choose the optimal groundwater extraction method in the case of a coastal unconfined aquifer. A comparison is made of the groundwater extraction methods in a freshwater aquifer of limited thickness occurring in coastal dunes in the eastern region of the Province of Buenos Aires (Argentina). The negative effects brought about by the wrong use of the groundwater extraction methods are analysed, because, as a result of excessive extraction, such methods lead to the dramatic decrease of the freshwater reserves. The decision tree is a useful tool to assist decision-makers as it suggests the most suitable groundwater extraction method options (vertical wells or wellpoints), as well as identifying areas that are unsuitable for sustainable groundwater extraction. Full Article
tool Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond [Review Articles] By pharmrev.aspetjournals.org Published On :: 2020-02-27T12:11:24-08:00 Ubiquitin (UB) transfer cascades consisting of E1, E2, and E3 enzymes constitute a complex network that regulates a myriad of biologic processes by modifying protein substrates. Deubiquitinating enzymes (DUBs) reverse UB modifications or trim UB chains of diverse linkages. Additionally, many cellular proteins carry UB-binding domains (UBDs) that translate the signals encoded in UB chains to target proteins for degradation by proteasomes or in autophagosomes, as well as affect nonproteolytic outcomes such as kinase activation, DNA repair, and transcriptional regulation. Dysregulation of the UB transfer pathways and malfunctions of DUBs and UBDs play causative roles in the development of many diseases. A greater understanding of the mechanism of UB chain assembly and the signals encoded in UB chains should aid in our understanding of disease pathogenesis and guide the development of novel therapeutics. The recent flourish of protein-engineering approaches such as unnatural amino acid incorporation, protein semisynthesis by expressed protein ligation, and high throughput selection by phage and yeast cell surface display has generated designer proteins as powerful tools to interrogate cell signaling mediated by protein ubiquitination. In this study, we highlight recent achievements of protein engineering on mapping, probing, and manipulating UB transfer in the cell. Significance Statement The post-translational modification of proteins with ubiquitin alters the fate and function of proteins in diverse ways. Protein engineering is fundamentally transforming research in this area, providing new mechanistic insights and allowing for the exploration of concepts that can potentially be applied to therapeutic intervention. Full Article
tool Development and Implementation of the Readiness Assessment of Emerging Adults With Type 1 Diabetes Diagnosed in Youth (READDY) Tool By spectrum.diabetesjournals.org Published On :: 2020-02-14T06:59:49-08:00 Full Article
tool Molar element ratio analysis of lithogeochemical data: a toolbox for use in mineral exploration and mining By geea.lyellcollection.org Published On :: 2020-05-01T00:30:32-07:00 Molar element ratio analysis of element concentrations consists of four basic tools that provide substantial insight into the lithogeochemistry (and mineralogy) of rocks under examination. These tools consist of: (1) conserved element ratio analysis; (2) Pearce element ratio analysis; (3) general element ratio analysis; and (4) lithogeochemical mineral mode analysis. Conserved element ratio analysis is useful in creating a chemostratigraphic model for the host rocks to mineral deposits, whereas Pearce element ratio analysis and general element ratio analysis are primarily used to identify mineralogical and metasomatic controls on rock compositions and to investigate and quantify the extent of the material transfers that formed the host rocks and mineralization. Lithogeochemical mineral mode analysis converts element concentrations into mineral concentrations using a matrix-based change-of-basis operation, allowing lithogeochemical data to be interpreted in terms of mineral modes. It can be used to provide proper names to rocks, an important activity for an exploration geologist because of the implications that rock names have on genetic processes and mineral deposit models. This paper provides a review of the theoretical foundations of each of these four tools and then illustrates how these techniques have been used in a variety of exploration applications to assist in the search for, evaluation and planning of, and the mining of mineral deposits. Examples include the evaluation of total digestion lithogeochemical datasets from mineral deposits hosted by igneous and sedimentary rocks and formed by hydrothermal and igneous processes. In addition, this paper illustrates a more recent geometallurgical application of these methods, whereby the mineral proportions determined by lithogeochemical mineral mode analysis are used to predict rock properties and obtain the ore body knowledge critical for resource evaluation, mine planning, mining and mine remediation. Thematic collection: This article is part of the Exploration 17 collection available at: https://www.lyellcollection.org/cc/exploration-17 Full Article
tool CRISPR Tools To Control Gene Expression in Bacteria [Review] By mmbr.asm.org Published On :: 2020-04-01T05:29:40-07:00 CRISPR-Cas systems have been engineered as powerful tools to control gene expression in bacteria. The most common strategy relies on the use of Cas effectors modified to bind target DNA without introducing DNA breaks. These effectors can either block the RNA polymerase or recruit it through activation domains. Here, we discuss the mechanistic details of how Cas effectors can modulate gene expression by blocking transcription initiation or acting as transcription roadblocks. CRISPR-Cas tools can be further engineered to obtain fine-tuned control of gene expression or target multiple genes simultaneously. Several caveats in using these tools have also been revealed, including off-target effects and toxicity, making it important to understand the design rules of engineered CRISPR-Cas effectors in bacteria. Alternatively, some types of CRISPR-Cas systems target RNA and could be used to block gene expression at the posttranscriptional level. Finally, we review applications of these tools in high-throughput screens and the progress and challenges in introducing CRISPR knockdown to other species, including nonmodel bacteria with industrial or clinical relevance. A deep understanding of how CRISPR-Cas systems can be harnessed to control gene expression in bacteria and build powerful tools will certainly open novel research directions. Full Article
tool Continuous Glucose Monitoring As a Behavior Modification Tool By clinical.diabetesjournals.org Published On :: 2020-04-15T12:00:21-07:00 Real-time continuous glucose monitoring (CGM) use may lead to behavioral modifications in food selection and physical activity, but there are limited data on the utility of CGM in facilitating lifestyle changes. This article describes an 18-item survey developed to explore whether patients currently using CGM believe the technology has caused them to change their behavior. Full Article
tool Trump campaign releases new mobile app, tooled for virtual volunteering By www.nbcnews.com Published On :: Thu, 23 Apr 2020 15:35:58 GMT After teasing it for seven months, President Donald Trump’s re-election campaign finally launched a new phone application to rally supporters on Thursday that has been re-imagined for the virtual political age. Full Article
tool Prediction tool shows how forest thinning may increase Sierra Nevada snowpack By www.sciencedaily.com Published On :: Thu, 07 May 2020 16:40:07 EDT Thinning the Sierra Nevada forest by removing trees by hand or using heavy machinery is one of the few tools available to manage forests. However, finding the best way to thin forests by removing select trees to maximize the forest's benefits for water quantity, water quality, wildfire risk and wildlife habitat remains a challenge for resource managers. Full Article
tool Neanderthals were choosy about making bone tools By www.sciencedaily.com Published On :: Fri, 08 May 2020 11:28:56 EDT Evidence continues to mount that the Neanderthals, who lived in Europe and Asia until about 40,000 years ago, were more sophisticated people than once thought. A new study shows that Neanderthals chose to use bones from specific animals to make a tool for specific purpose: working hides into leather. Full Article