development

Moving Beyond “Root Causes:” The Complicated Relationship between Development and Migration

Development assistance may be a blunt tool for reshaping migration patterns—and indeed one that could increase flows over the short term. Shifting the focus away from increasing individuals’ skills and assets toward investments in the broader economic or governance structures that are a prerequisite for growth and stability may offer more alternatives to emigration in the long run.




development

Mind the Gap: Bringing Migration into Development Partnerships and Vice Versa

As policymakers look for ways to address the drivers of illegal immigration, many have called for migration aims to be incorporated into development work and development tools into migration partnerships. This policy brief analyzes the benefits and risks of heightened cooperation between actors in these fields, and identifies areas where joint initiatives may prove fruitful.




development

Embracing Emigration: The Migration-Development Nexus in Albania

From ongoing emigration flows and a surge in asylum seekers, to more than 150,000 returnees, this country profile examines contemporary and historical migration trends in Albania. Driven by extreme poverty and unemployment, more than one-third of Albania's population has emigrated in the last 25 years. The government now seeks to capitalize on diaspora resources by linking migration and development policies.




development

The Philippines: Beyond Labor Migration, Toward Development and (Possibly) Return

In the Philippines, a pervasive culture of migration has led millions to seek opportunities abroad, particularly since an economic downturn in the 1970s. The government has long embraced exporting labor as official economic policy, but over time, the focus has shifted: first to protecting workers overseas and much more recently to linking migration and development. This article explores the evolution of Filipino migration policy and trends.




development

Central American Development: Two Decades of Progress and Challenges for the Future

This report summarizes the economic and social development policy achievements of Central American countries over the past 20 years, as well as the notable obstacles to development that remain. The author identifies long-term challenges and outlines how they can be incorporated into a new development agenda.




development

What We Know About Migration and Development

This policy brief, which concludes a nine-brief series examining what is known about the linkages between migration and development, suggests that the policy framework on migration and development remains relatively weak, and few development agencies have made it a priority to promote the positive impact of international migration.




development

Reimagining Skilled Migration Partnerships to Support Development

While partnerships to facilitate skilled migration have had mixed success in the past, the Global Compact for Migration is advancing a new approach that may change this. This policy brief compares this new partnership model with the traditional one, highlighting the questions policymakers will need to answer if they are to encourage mobility, sustain employer engagement, and see development benefits in countries of origin.




development

Migration, Development, and Global Governance: From Crisis toward Consolidation

Migration and development policy discussions have edged closer to each other on the international stage. The adoption of the Global Compact for Migration in December 2018 marks an important milestone. As all eyes turn toward the compact’s implementation, this brief examines some of the key topics states have pledged to work more closely on—from labor migration and migrants’ rights, to returns and reintegration.




development

Consensus Development Conference on Insulin Resistance: 5-6 November 1997

American Diabetes Association
Feb 1, 1998; 21:310-314
Consensus Development Conference Report




development

Consensus Development Conference on the Diagnosis of Coronary Heart Disease in People With Diabetes: 10-11 February 1998, Miami, Florida

American Diabetes Association
Sep 1, 1998; 21:1551-1559
Consensus Development Conference Report




development

Member dentist honored for contributions in SNODENT development

The international group SNOMED International honored ADA member dentist Dr. Mark Jurkovich with the Award of Excellence for spearheading the important work the ADA has done on SNODENT, the group announced Jan. 16.




development

Study: Evidence does not support classifying fluoride as cognitive neurodevelopmental hazard

The National Academies of Sciences, Engineering, and Medicine announced March 5 that it does not find that the National Toxicology Program adequately supported its conclusion that fluoride is “presumed” to be a cognitive neurodevelopmental hazard to humans.




development

Brain model links herpes virus to development of Alzheimer's disease

Bio-engineered models of the human brain infected with herpes simplex virus-1 develop many of the same characteristics found in Alzheimer's disease, according to a new analysis published by Science Advances.




development

Decreased Vagal Activity and Deviation in Sympathetic Activity Precedes Development of Diabetes

OBJECTIVE

The objective of this study was to examine whether altered heart rate variability (HRV) could predict the risk of diabetes in Asians.

RESEARCH DESIGN AND METHODS

A cohort study was conducted in 54,075 adults without diabetes who underwent 3-min HRV measurement during health checkups between 2011 and 2014 at Kangbuk Samsung Hospital. We analyzed the time domain (SD of the normal-to-normal interval [SDNN] and root mean square differences of successive normal-to-normal interval [RMSSD]) and the frequency domain (total power, normalized low-frequency power [LF], and normalized high-frequency power [HF] and LF/HF ratio). We compared the risk of diabetes until 2017 according to tertiles of heart rate and HRV variables, with tertile 1 serving as the reference group.

RESULTS

During 243,758.2 person-years, 1,369 subjects were diagnosed with diabetes. Both time and frequency domain variables were lower in the group with diabetes, with the exception of those with normalized LF and LF/HF ratio. In Cox analysis, as SDNN, RMSSD, and normalized HF tertiles increased, the risk of diabetes decreased (hazard ratios [95% CIs] of tertile 3: 0.81 [0.70–0.95], 0.76 [0.65–0.90], and 0.78 [0.67–0.91], respectively), whereas the risk of diabetes increased in the case of heart rate, normalized LF, and LF/HF ratio (hazard ratios [95% CIs] of tertile 3: 1.41 [1.21–1.65], 1.32 [1.13–1.53], and 1.31 [1.13–1.53), respectively) after adjusting for age, sex, BMI, smoking, drinking, systolic blood pressure, lipid level, CRP, and HOMA of insulin resistance.

CONCLUSIONS

Abnormal HRV, especially decreased vagal activity and deviation in sympathovagal imbalance to sympathetic activity, might precede incident diabetes.




development

Dietary Manganese, Plasma Markers of Inflammation, and the Development of Type 2 Diabetes in Postmenopausal Women: Findings From the Womens Health Initiative

OBJECTIVE

To examine the association between manganese intake and the risk of type 2 diabetes in postmenopausal women and determine whether this association is mediated by circulating markers of inflammation.

RESEARCH DESIGN AND METHODS

We included 84,285 postmenopausal women without a history of diabetes from the national Women’s Health Initiative Observational Study (WHI-OS). Replication analysis was then conducted among 62,338 women who participated in the WHI-Clinical Trial (WHI-CT). Additionally, data from a case-control study of 3,749 women nested in the WHI-OS with information on biomarkers of inflammation and endothelial dysfunction were examined using mediation analysis to determine the relative contributions of these known biomarkers by which manganese affects type 2 diabetes risk.

RESULTS

Compared with the lowest quintile of energy-adjusted dietary manganese, WHI-OS participants in the highest quintile had a 30% lower risk of type 2 diabetes (hazard ratio [HR] 0.70 [95% CI 0.65, 0.76]). A consistent association was also confirmed in the WHI-CT (HR 0.79 [95% CI 0.73, 0.85]). In the nested case-control study, higher energy-adjusted dietary manganese was associated with lower circulating levels of inflammatory biomarkers that significantly mediated the association between dietary manganese and type 2 diabetes risk. Specifically, 19% and 12% of type 2 diabetes risk due to manganese were mediated through interleukin 6 and hs-CRP, respectively.

CONCLUSIONS

Higher intake of manganese was directly associated with a lower type 2 diabetes risk independent of known risk factors. This association may be partially mediated by inflammatory biomarkers.




development

Key Immigration Laws and Policy Developments Since 1986

A timeline of key immigration laws and policy developments between 1986 and 2013.




development

New Opportunities? ESSA and Its Implications for Dual Language Learners and ECEC Workforce Development

Enactment of the Every Student Succeeds Act (ESSA) in 2015 introduced opportunities to use federal funds to strengthen the early childhood education and care (ECEC) workforce as a means of better meeting the needs of the growing and increasingly diverse young child population.




development

Knowledge sharing for the development of learning resources : theory, method, process and application for schools, communities and the workplace : a UNESCO-PNIEVE resource / by John E. Harrington, Professor Emeritis.

The Knowledge Sharing for the Development of Learning Resources tutorial provides a professional step forward, a learning experience that leads to recognition that your leadership is well founded as well as ensuring that participants in the development of learning resources recognize they are contributing to an exceptional achievement.




development

What SACAT does and recent developments / presented by Barbara Johns, Executive Senior Member, Housing and Civil Stream SACAT.




development

Latest Developments in Defamation Law Duffy & Trkulja.




development

Forum 2019 : 4B Privacy law panel : recent developments and isues : slides / presented by Kelly Scott, Crown Solicitors Office.




development

Forum 2019 : 4B Privacy law panel : recent developments and isues : slides / presented by Laura Butler, Australian Government Soliciter.




development

Forum 2019 : 7B Privilege : recent developments as to privilege self: incrimination and stay of civil proceedings, privilege over investigative reports and privilege over instructions to experts / paper presented by Alex Lazarevich, Anthony Mason Chambers




development

Australian government response to the Senate Finance and Public Administration References Committee inquiry report : the appropriateness and effectiveness of the objectives, design, implementation and evaluation of the Community Development Program (CDP)




development

Award of funding under the Regional Jobs and Investment Packages : Department of infrastructure, Transport, Cities and Regional Development, Department of Industry, Inovation and Science / The Auditor General.

"The objective of the audit was to assess whether the award of funding under the RJIP program was informed by appropriate departmental advice and that processes complied with the grants administration framework."--Page 8.




development

The community development programme : evaluation of participation and employment outcomes / Department of the Prime Minister and Cabinet.




development

Skills and workforce development agreement / Australian Government Productivity Commission.

The National Agreement for Skills and Workforce Development (NASWD) was agreed by the Australian, State and Territory governments in 2009 and updated in 2012. The NASWD sets out goals for skills attainment by Australians through the vocational education and training (VET) system and commitments to reforms to ensure that the system is accessible, produces high quality services and operates efficiently. This study will assess progress made by governments against the NASWD, and whether the agreement is still an effective long-term framework for government policy and cooperation.




development

The development of meat inspection / by Stewart Stockman.

London : Adlard, 1899.




development

The development of the child / by Nathan Oppenheim.

New York : Macmillan, 1898.




development

The development of the human body : a manual of human embryology / by J. Playfair McMurrich.

London : Rebman, 1910.




development

The development of the human body : a manual of the human embryology / by J. Playfair McMurrich.

London : Rebman, 1903.




development

The development of the teaching of law in the University of Edinburgh / by John P. Coldstream.

Edinburgh : printed by Morrison & Gibb, 1884.




development

Development of tolerance and cross-tolerance to psychomotor effects of benzodiazepines in man / by Kari Aranko.

Helsinki : Department of Pharmacology and Toxicology, University of Helsinki, 1985.




development

Recent developments in complex and spatially correlated functional data

Israel Martínez-Hernández, Marc G. Genton.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 2, 204--229.

Abstract:
As high-dimensional and high-frequency data are being collected on a large scale, the development of new statistical models is being pushed forward. Functional data analysis provides the required statistical methods to deal with large-scale and complex data by assuming that data are continuous functions, for example, realizations of a continuous process (curves) or continuous random field (surfaces), and that each curve or surface is considered as a single observation. Here, we provide an overview of functional data analysis when data are complex and spatially correlated. We provide definitions and estimators of the first and second moments of the corresponding functional random variable. We present two main approaches: The first assumes that data are realizations of a functional random field, that is, each observation is a curve with a spatial component. We call them spatial functional data . The second approach assumes that data are continuous deterministic fields observed over time. In this case, one observation is a surface or manifold, and we call them surface time series . For these two approaches, we describe software available for the statistical analysis. We also present a data illustration, using a high-resolution wind speed simulated dataset, as an example of the two approaches. The functional data approach offers a new paradigm of data analysis, where the continuous processes or random fields are considered as a single entity. We consider this approach to be very valuable in the context of big data.




development

Recent developments on genus Chaetomium

9783030316129 (electronic bk.)




development

Plant microRNAs : shaping development and environmental responses

9783030357726 (electronic bk.)




development

Insect metamorphosis : from natural history to regulation of development and evolution

Bellés, X., author
9780128130216




development

In china's wake : how the commodity boom transformed development strategies in the global south

Jepson, Nicholas, author.
9780231547598 electronic book




development

Evolutionary developmental biology : a reference guide

9783319330389 (electronic bk.)




development

Development of biopharmaceutical drug-device products

9783030314156 (electronic bk.)




development

Current developments in biotechnology and bioengineering : resource recovery from wastes

0444643222




development

Biomedical product development : bench to bedside

9783030356262 (electronic bk.)




development

Jamboree Begins Construction on Capstone Development to Change...

In a public-private partnership to develop housing, resident services and hope for 102 working families in Haster Orangewood community, Jamboree Housing Corporation and the City of Anaheim announce...

(PRWeb April 27, 2020)

Read the full story at https://www.prweb.com/releases/jamboree_begins_construction_on_capstone_development_to_change_trajectory_of_neighborhood_in_anaheim_ca/prweb17073166.htm




development

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

John D. Cahoy
Jan 2, 2008; 28:264-278
Cellular




development

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex

EL Bienenstock
Jan 1, 1982; 2:32-48
Articles




development

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

John D. Cahoy
Jan 2, 2008; 28:264-278
Cellular




development

A Model to Study NMDA Receptors in Early Nervous System Development

N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels that play critical roles in neuronal development and nervous system function. Here, we developed a model to study NMDARs in early development in zebrafish, by generating CRISPR-mediated lesions in the NMDAR genes, grin1a and grin1b, which encode the obligatory GluN1 subunits. While receptors containing grin1a or grin1b show high Ca2+ permeability, like their mammalian counterpart, grin1a is expressed earlier and more broadly in development than grin1b. Both grin1a–/– and grin1b–/– zebrafish are viable. Unlike in rodents, where the grin1 knockout is embryonic lethal, grin1 double-mutant fish (grin1a–/–; grin1b–/–), which lack all NMDAR-mediated synaptic transmission, survive until ~10 d dpf (days post fertilization), providing a unique opportunity to explore NMDAR function during development and in generating behaviors. Many behavioral defects in the grin1 double-mutant larvae, including abnormal evoked responses to light and acoustic stimuli, prey-capture deficits, and a failure to habituate to acoustic stimuli, are replicated by short-term treatment with the NMDAR antagonist MK-801, suggesting that they arise from acute effects of compromised NMDAR-mediated transmission. Other defects, however, such as periods of hyperactivity and alterations in place preference, are not phenocopied by MK-801, suggesting a developmental origin. Together, we have developed a unique model to study NMDARs in the developing vertebrate nervous system.

SIGNIFICANCE STATEMENT Rapid communication between cells in the nervous system depends on ion channels that are directly activated by chemical neurotransmitters. One such ligand-gated ion channel, the NMDAR, impacts nearly all forms of nervous system function. It has been challenging, however, to study the prolonged absence of NMDARs in vertebrates, and hence their role in nervous system development, due to experimental limitations. Here, we demonstrate that zebrafish lacking all NMDAR transmission are viable through early development and are capable of a wide range of stereotypic behaviors. As such, this zebrafish model provides a unique opportunity to study the role of NMDAR in the development of the early vertebrate nervous system.




development

7 things you should know about FAO and the Post-2015 development agenda

As FAO launches dedicated webpages on post-2015, here are seven things to know about the process and how FAO is playing its part. 7 - Post-2015 development agenda - The name refers to the process through which Member States agree on a new global development framework to succeed the Millennium Development Goals (MDGs), eight goals that followed the UN Millennium Declaration [...]




development

Changing the future of migration by investing in food security and rural development

Migration has always existed. It has been a means to reunite with family, to find better jobs, to have a new experience or to start a better life. In 2015, the number of people migrating was up to 1 out of every 7 people in the world.   When it is a choice, migration can be a good way to spread [...]




development

Resource partners round table calls for investment in better data for the Sustainable Development Goals (SDGs)

Four years into the 2030 Agenda, there is still a large gap in data to understand where the world stands in achieving its shared goals, the SDGs. To support [...]