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Mucinous carcinoma with micropapillary features is morphologically, clinically and genetically distinct from pure mucinous carcinoma of breast




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An analysis of the effect of mu-opioid receptor gene (<i>OPRM1</i>) promoter region DNA methylation on the response of naltrexone treatment of alcohol dependence




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Identification of gene modules associated with survival of diffuse large B-cell lymphoma treated with CHOP-based chemotherapy




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Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment




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Publisher Correction: ASPI: a public–private partnership to develop treatments for autism




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Targeting CDK12 to treat DM1




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Why Oral Cancer Threatens Men

Researchers wrestle with the rising rates of virus-related tumors




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Coronavirus diaries: creature comforts




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Daily briefing: Convalescent serum — the antibody-laden blood of survivors — lines up as first-choice treatment for coronavirus




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China is promoting coronavirus treatments based on unproven traditional medicines




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Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma




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Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide




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Hypertension in rheumatic diseases: prevalence, awareness, treatment, and control rates according to current hypertension guidelines




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Nucleation seed size determines amyloid clearance and establishes a barrier to prion appearance in yeast




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Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals




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The continued threat of emerging flaviviruses




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A Buddhism Critic Goes on a Silent Buddhist Retreat

Something weird happens to a skeptical science writer during a week of meditation, chanting and skygazing




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Early assessment of <i>KRAS</i> mutation in cfDNA correlates with risk of progression and death in advanced non-small-cell lung cancer




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Molecular profiling of stroma highlights stratifin as a novel biomarker of poor prognosis in pancreatic ductal adenocarcinoma




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The untapped potential of ascites in ovarian cancer research and treatment




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Clinical and radiographic evaluation of indirect pulp treatment of young permanent molars using photo-activated oral disinfection versus calcium hydroxide: a randomized controlled pilot trial




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Convalescent serum lines up as first-choice treatment for coronavirus




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African-American men with low-risk prostate cancer treated with radical prostatectomy in an equal-access health care system: implications for active surveillance




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Effect of simulated microgravity on the antidiabetic properties of wheatgrass (<i>Triticum aestivum</i>) in streptozotocin-induced diabetic rats

npj Microgravity, Published online: 24 February 2020; doi:10.1038/s41526-020-0096-x

Effect of simulated microgravity on the antidiabetic properties of wheatgrass (Triticum aestivum) in streptozotocin-induced diabetic rats




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Cell Death & Disease




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




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Transcription factors in ferroptotic cell death




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Strain creates a trion factory




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Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy




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Inducing senescence sensitizes pancreatic tumours to therapies




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Universal screening for hepatitis C virus infection should be linked to universal treatment access




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Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys




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A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology




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Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression




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Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis




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Nonoperative treatment of traumatic spinal injuries in Tanzania: who is not undergoing surgery and why?




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Pomalidomide, dexamethasone, and daratumumab in relapsed refractory multiple myeloma after lenalidomide treatment




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High-risk additional chromosomal abnormalities at low blast counts herald death by CML




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Treatment and management of cognitive dysfunction in patients with multiple sclerosis




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Generational trends in US opioid-overdose deaths




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Age and generational patterns of overdose death risk from opioids and other drugs




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Trump Turned the Death Count Into a Story About Himself

Official figures exclude thousands who have died during the pandemic. To draw the right lessons, the United States needs an accurate tally of the victims.




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Trump Turned the Death Count Into a Story About Himself

Official figures exclude thousands who have died during the pandemic. To draw the right lessons, the United States needs an accurate tally of the victims.




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Biallelic mutations in <i>SORD</i> cause a common and potentially treatable hereditary neuropathy with implications for diabetes




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The Need for Creative and Effective Nuclear Security Vulnerability Assessment and Testing

Realistic, creative vulnerability assessment and testing are critical to finding and fixing nuclear security weaknesses and avoiding over-confidence. Both vulnerability assessment and realistic testing are needed to ensure that nuclear security systems are providing the level of protection required. Systems must be challenged by experts thinking like adversaries, trying to find ways to overcome them. Effective vulnerability assessment and realistic testing are more difficult in the case of insider threats, and special attention is needed. Organizations need to find ways to give people the mission and the incentives to find nuclear security weaknesses and suggest ways they might be fixed. With the right approaches and incentives in place, effective vulnerability assessment and testing can be a key part of achieving and sustaining high levels of nuclear security.




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Illuminating Homes with LEDs in India: Rapid Market Creation Towards Low-carbon Technology Transition in a Developing Country

This paper examines a recent, rapid, and ongoing transition of India's lighting market to light emitting diode (LED) technology, from a negligible market share to LEDs becoming the dominant lighting products within five years, despite the country's otherwise limited visibility in the global solid-state lighting industry.




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Creating Subnational Climate Institutions in China

This discussion paper (available in English and Chinese) describes the evolution of decentralization over the reform period that began in China in 1978, different theories of institutional change in China, and how the empirical and theoretical literatures help scholars and policymakers understand the development of institutions for governing GHG-emitting activities.




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Illuminating Homes with LEDs in India: Rapid Market Creation Towards Low-carbon Technology Transition in a Developing Country

This paper examines a recent, rapid, and ongoing transition of India's lighting market to light emitting diode (LED) technology, from a negligible market share to LEDs becoming the dominant lighting products within five years, despite the country's otherwise limited visibility in the global solid-state lighting industry.




eat

Creating Subnational Climate Institutions in China

This discussion paper (available in English and Chinese) describes the evolution of decentralization over the reform period that began in China in 1978, different theories of institutional change in China, and how the empirical and theoretical literatures help scholars and policymakers understand the development of institutions for governing GHG-emitting activities.




eat

Illuminating Homes with LEDs in India: Rapid Market Creation Towards Low-carbon Technology Transition in a Developing Country

This paper examines a recent, rapid, and ongoing transition of India's lighting market to light emitting diode (LED) technology, from a negligible market share to LEDs becoming the dominant lighting products within five years, despite the country's otherwise limited visibility in the global solid-state lighting industry.