Earlier genetic and inhibitor studies have shown that epigenetic regulation of gene expression is critical for malaria parasite survival in multiple life stages and a promising target for new anti-malarials. We therefore evaluated the activity of 350 diverse epigenetic inhibitors against multiple stages of Plasmodium falciparum. We observed ≥90% inhibition at 10 μM for 28% of compounds against asexual blood stages and early gametocytes, of which a third retained ≥90% inhibition at 1 μM.

Timo Werner's penalty has given Leipzig a narrow advantage, although Spurs have history when it comes to turning round a 1-0 home defeat.

Jake Griggs, who will graduate Saturday with a 3.95 GPA with dual majors in management and political science, has been named Smeal’s spring 2020 management and organization student marshal.

With speed and ingenuity, more than 100 researchers across Penn State are shifting their research programs to address the COVID-19 crisis, thanks to funding from a seed grant initiative led by the Huck Institutes of the Life Sciences. In total, the initiative awarded $2.25 million to 47 teams of researchers from three campuses, 10 colleges and more than 25 departments.

MASC has successfully designed and delivered critical equipment and supplies needed to protect health care workers and patients during the COVID-19 pandemic.

Two alumni and one community partner contribute clinical medicine and research experience during the pandemic

Using their unique skills and experiences, three LaunchBox grant recipients are providing a variety of COVID-19 relief efforts.

When starting your savings journey, contribute the maximum tax-free allocation and then explore further options that suit your risk appetite and profile, says an expert.

By the end of February, most taxpayers are looking for every opportunity to reduce their tax liabilities.

Each year, Penn State honors several students for the highest levels of academic excellence, outstanding leadership and meritorious service. The 2020 student award recipients exemplify best practices and achievements among Penn State students, reflecting the University's mission of teaching, research and service.

A new endowed scholarship has been created to support those studying science, technology, engineering or math at Penn State Hazleton.

You can enjoy your AirPods Pro even more if you know how to fully use and customize them. Here are our top tips and tricks to get the most out of Apple’s wireless earbuds.

Getting started is as easy as picking a show and pressing play. However, there are a few tricks you can use to get the most out of your viewing experience, like killing autoplay trailers.

Is your favorite music missing on your iPhone or iPad? Maybe you inadvertently turned off syncing or accidentally deleted those tunes. All is not lost; here's how to recover your music.

New iPods can be a critical part of Apple's strategy. Just don't think of them as music players.

Apple quietly revealed new iPods today with new colors and better specs.

As the Apple iPod turns 14, we take a look back at its history and influence over the last decade-plus.

The Apple iPod touch is the best media player there is if you don't want a cellular connection.

"It's like a cinderblock," one seven-year-old said of Apple's original MP3 player.

Customers in the U.S. should begin noticing in-store changes starting today.

A new high-res audio player looks like a wooden flask and has a tie-up with Tidal.

Streaming services and complicated gadgets aren't for me. Sometimes single-purpose retro tech is all you need.

There's a new iPod touch! A new iPod touch? Sure. It's going to be popular with parents, with people who exercise, and with anyone who wants low-cost access to iMessage and FaceTime.

Apple's 2019 iPod touch is a small, light handheld media player that's terrific for kids and anyone who doesn't want a full-fledged smartphone.

While we wait for Apple Arcade to launch for iOS devices, Google is preparing its own app/game subscription service for Android called Play Pass.

The 1TB Samsung 860 EVO m.2 SSD is just $119 today, the 10.2-inch iPad is back in stock with a 15 percent discount, and you can save $250 on the 13-inch MacBook Pro.

A new guide from the National Center for Learning Disabilities and Understood.org offers advice on how school leaders can best serve students with disabilities and support special education teachers.

The need for materials, training, guidance from district administrators, and access to staff with expertise in serving students with disabilities is especially acute in schools that serve primarily black and Latino students, a new survey finds.

DHCP is fine, unless you're looking to perform advanced networking tasks. Here's how to set a Static IP address (or DHCP reservation) for any device on your network.

Falkirk chairman Gary Deans tonight slammed Ladbrokes Premiership clubs for scuppering league reconstruction hopes - and called for change at the top of Scottish football.

PARTICK Thistle today branded the SPFL a "disgrace" for failing to inform them that league reconstruction had been abandoned and revealed they are "deeply angered" by Ladbrokes Premiership clubs scuppering the plans.

A family of four was caught flouting lockdown restrictions after attempting to travel to Motherwell for a mini-break.

Staff from NHS England have been asked to travel hundreds of miles to Scotland to be tested for coronavirus, according to reports.

A family who was fined for travelling more than 400 miles for the bank holiday weekend have been slammed online by politicians and Scots.

Understanding how research is actually used by district leaders is essential for research-practice partnerships to effectively bridge research and practice in education.

T. Michael O'Shea
Jul 1, 1999; 104:15-21
ARTICLES

Do your bit for the environment and reduce clutter in your own home or office by cutting down on the paper you use and keep. Learn how to go paperless with productivity expert Jill Duffy's tips and suggestions.

New data from the National Center for Education Statistics find that principals at private schools tend to have more experience, 9.7 years on average leading schools versus 6.8 years for public school principals.

Online learning holds great potential to transform rural education by ensuring that every student has access to great instruction.

A survey found that while fewer parents think students should spend considerable time in front of screens in schools, teacher support was unchanged.

Even great innovations can fail. Will blended learning be one of them? These five factors may help us determine if the new educational model has reached a tipping point.

The intercollege minor in entrepreneurship and innovation (ENTI) continues to spread its influence as it graduates its largest number of students this spring with 153 across eight clusters.

Mobicip gives you the basic tools you need to monitor your children's web and app activity, but the lack of sophisticated time- and location-tracking features hold it back.

Samsung will announce the next-generation foldable phone later this month; however, a newly-leaked hands-on video reveals exactly how its Galaxy Z Flip will perform in the real world.

Chinese manufacturer TCL will no longer make BlackBerry-branded phones, nor will it have the right to 'design, manufacture or sell any new BlackBerry mobile devices' after August 2020.

The Samsung Galaxy Z Flip is the first folding phone to really work, but it's still a costly and potentially fragile fashion object rather than a mainstream hit.

The Laurel Highlands boys basketball team will be honored at the USCAA Men’s Division II Basketball National Championship Game on Wednesday, March 11, at Penn State Fayette, The Eberly Campus.

The Ratline: Love, Lies and Justice on the Trail of a Nazi Fugitive

Bellisario College internship office seeks to bolster its offerings with feedback from alumni and friends, as well as some creative approaches.