ap

Two in one: merging photoactivated chemotherapy and photodynamic therapy to fight cancer

Chem. Sci., 2024, 15,17760-17780
DOI: 10.1039/D4SC04608K, Perspective
Open Access
Kirill M. Kuznetsov, Kevin Cariou, Gilles Gasser
Combining photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) into one single compound allows to achieve more efficient light-induced therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Dilute nanocomposites for capacitive energy storage: progress, challenges and prospects

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05437G, Perspective
Open Access
Li Li, Wenhan Xu, Guanchun Rui, Shixian Zhang, Qiming Zhang, Qing Wang
Electrostatic capacitors (ECs) are critical components in advanced electronics and electric power systems due to their rapid charge-discharge rate and high power density. While polymers are ideal for ECs due...
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

The chirality-induced spin selectivity effect in asymmetric spin transport: from solution to device applications

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05736H, Review Article
Open Access
Ritu Gupta, Anujit Balo, Rabia Garg, Amit Kumar Mondal, Koyel Banerjee Ghosh, Prakash Chandra Mondal
This review highlights recent experimental findings related to the chirality-induced spin selectivity effect. This effect is demonstrated to explain asymmetric electron's spin transport in chiral molecules for various technological applications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Photo-triggered NO release of nitrosyl complexes bearing first-row transition metals and therapeutic applications

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06820C, Review Article
Open Access
Seungwon Sun, Jisu Choe, Jaeheung Cho
In biological systems, nitric oxide (NO) is a crucial signaling molecule that regulates a wide range of physiological and pathological processes. Given the significance of NO, there has been considerable...
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

A metabologenomics strategy for rapid discovery of polyketides derived from modular polyketide synthases

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC04174G, Edge Article
Open Access
Run-Zhou Liu, Zhihan Zhang, Min Li, Lihan Zhang
A metabologenomics workflow using mass defect filtering (MDF) and bioinformatics-based structural prediction was established for rapid screening of modular polyketide natural products, and led to the identification of 22 polyketides.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Merging nucleophilic phosphine catalysis and photocatalysis for the rapid assembly of 2-oxabicyclo-[2.1.1]hexane scaffolds from feedstock allyl alcohols

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC06684G, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
David M. Whalley, Luca Carlino, Okky Dwichandra Putra, Niall A. Anderson, Susannah C. Coote, Olivier Lorthioir
A synthesis of 2-oxabicyclo-[2.1.1]hexanes from readily available allyl alcohols and electron-poor arylalkynes. The transformation utilises phosphine catalysis and energy transfer catalysis for rapid assembly of these diverse scaffolds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Resonance Plasmonic Coupling: Selective Enhancement of Band Edge Emission over Trap State Emission of CdSe Quantum Dots

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC04960H, Edge Article
Open Access
Livin Paul, Elizabeth Mariam Thomas, Akshaya Chemmangat, Stephen Gray, K. George Thomas
The photoluminescence properties of quantum dots (QDs) are often enhanced by eliminating surface trap states through chemical methods. Alternatively, a physical approach is presented here for improving photoluminescence purity in...
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Differentiating carrier protein interactions in biosynthetic pathways using dapoxyl solvatochromism

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05499G, Edge Article
Open Access
Matthew G. Miyada, Yuran Choi, Kyle Rich, James J. La Clair, Michael D. Burkart
A highly sensitive solvatochromic system was developed to monitor the loading and interactivity of carrier proteins associated with fatty acid, polyketide and non-ribosomal peptide biosynthesis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Noncentrosymmetric tellurite halides created by a depolymerization strategy: toward strong SHG intensity and wide bandgap

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC06403H, Edge Article
Open Access
Dan-Dan Zhou, Chun-Li Hu, Xin-Wei Zhang, Jiang-Gao Mao, Fang Kong
Successful synthesis of centrosymmetric Ga(Te3O7)Br and non-centrosymmetric M2(OH)(TeO3)(Te2O5)X (M = Al, Ga; X = Br, Cl) using a depolymerization strategy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Cationic Al oxo-hydroxide clusters: syntheses, molecular structures, and functional applications

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05707D, Perspective
Open Access
Naoki Ogiwara, Wei Zhou, Sayaka Uchida
Al oxo-hydroxide clusters are formed through the hydrolysis of Al3+-containing solutions, exhibiting a diversity of sizes and shapes. The assembly of these clusters demonstrates functional applications, such as adsorption and heterogeneous catalysis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Rapid, Potent, and Persistent Covalent Chemical Probes to Deconvolute PI3Kα Signaling

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05459H, Edge Article
Open Access
Lukas Bissegger, Theodora Alexandra Alexandra Constantin, Erhan Keles, Luka Raguž, Isobel Barlow-Busch, Clara Orbegozo, Thorsten Schaefer, Valentina Borlandelli, Thomas Bohnacker, Rohitha SriRamaratnam, Alexander Schäfer, Matthias Gstaiger, John E. Burke, Chiara Borsari, Matthias Wymann
Chemical probes have gained importance in the elucidation of signal transduction in biology. Insufficient selectivity and potency, lack of cellular activity and inappropriate use of chemical probes has major consequences...
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Photoactivated hydride therapy under hypoxia beyond ROS

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06576J, Edge Article
Open Access
Xia Wang, Yijian Gao, Ting Wang, Zhaobin Wang, He Hang, Shengliang Li, Fude Feng
As compared to oxidative phototherapy, studies on reactive reductive species-participating photodynamic therapy (PDT) are rare. Porphyrins are typical photosensitizers restricted with oxygen level, but efficacy and selectivity are always uncompatible...
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Standing apart: Shivam Pradhan




ap

A long and colourful grapevine




ap

Shape-shifting with dance

Sanjukta Sinha dwells on belonging and relationships in Kin , her new contemporary Kathak production




ap

Mapping the Maya Nagari on celluloid

Take a trip down filmi history as the author tracks Mumbai’s numerous landmarks that have untiringly contributed to Hindi cinema’s imagery, almost becoming one with the narrative




ap

Share Market Highlights 18 April 2024: Sensex falls 330 pts, Nifty at 22,000; media, metal stocks shine, FMCG, healthcare drag

Sensex, Nifty updates on 18th April 2024: Equity benchmarks BSE Sensex and NSE Nifty extended losses on Thursday. As per provisional figures, BSE Sensex fell 332.23 pts or 0.46 per cent to trade at 72,611.45 as of 3.35 pm and Nifty 50 declined 103.70 pts or 0.47 per cent to trade at 22,044.20., Bharti Airtel, Power Grid Corp, M&M, BPCL, and Tata Steel were the top gainers, while Nestle, Apollo Hospitals, Axis Bank, HCL Technologies, and ONGC were the major laggards. The stocks that hit a 52-week high on the NSE include AAA Tech (19.33 per cent), Just Dial (12.95 per cent), Indo Tech (10 per cent) and Hi-Tech Gear (10 per cent).




ap

Should you invest in the Mirae Asset’s new mid and small cap factor ETF

Mirae Asset Nifty MidSmallcap400 Momentum Quality 100 ETF offers a blend of passive and smart-beta investing




ap

Markets correlate with economic performance, not political dispensation: Ashish Somaiyaa, CEO, WhiteOak Capital AMC

Ashish Somaiyaa, CEO, WhiteOak Capital AMC, on the impact of elections on the market and more




ap

Index funds to capitalise on corrections

Buying passive mutual funds, which simply mirror the basket of stocks making up an index, can help capitalising on a correction




ap

Quant MF under SEBI scrutiny: Deep dive into their mid- & small-cap schemes

A look at the stock positions of Quant Mutual Fund’s Mid- and Small-cap schemes, stress-test results (as of May 2024) and adjusted Net Asset Value (NAV)




ap

Not devoid of stock ideas, though markets aren’t cheap: Neelesh Surana, CIO, Mirae Asset Mutual Fund

Open to spinning off passive fund business under MF Lite, says Swarup Mohanty, Vice-Chairman and CEO, Mirae Asset Investment Managers




ap

Navi Nifty 500 Multicap 50:25:25 Index Fund: Should you subscribe?

The only fund tracking the Nifty 500 Multicap 50:25:25 Index till date. But does it offer some unique value proposition?




ap

Kotak Nifty Midcap 50 Index Fund: Just another Midcap Index Fund?

Only the second fund to give exposure to the Nifty Midcap 50 Index, how does it differ from other funds giving exposure to Midcaps?




ap

ICICI Prudential Flexicap Fund: A steady outperformer for the long term

ICICI Prudential Flexicap’s performance over the past three years places it in the top-quartile of its category




ap

Missed market turning points in our mid-cap fund: DSP MF’s Kalpen Parekh

Kalpen Parekh of DSP Mutual Fund on his fund house’s investment philosophy, the markets, valuation metrics and more




ap

Mirae Asset Large Cap Fund: Should you invest?

Large-caps offer relative safety from froth and Mirae Asset Large Cap Fund performed well in the class




ap

Why this large cap fund is a suitable investment in current volatile market

Canara Robeco Blue Chip Equity has consistently beaten the benchmark and delivered above-average performance




ap

Why investing in this large-cap fund can be rewarding in choppy markets

Kotak Bluechip is a steady outperformer and suits investors, with a medium risk appetite, saving for long-term goals




ap

Demographic dividend to demographic disaster

Raising the retirement age seems to be an invitation for demographic disaster.




ap

Rapid miRNA detection in skin interstitial fluid using a hydrogel microneedle patch integrated with DNA probes and graphene oxide

Lab Chip, 2024, 24,4989-4997
DOI: 10.1039/D4LC00715H, Paper
Hanjia Zheng, Fatemeh Keyvani, Sadegh Sadeghzadeh, Dragos F. Mantaila, Fasih A. Rahman, Joe Quadrilatero, Mahla Poudineh
A simple and rapid fluorescence-based sensor sensors using DNA functionalized graphene oxide for miRNA detection from skin interstitial fluid.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

A paper-in-polymer-pond (PiPP) hybrid microfluidic microplate for multiplexed ultrasensitive detection of cancer biomarkers

Lab Chip, 2024, 24,4962-4973
DOI: 10.1039/D4LC00485J, Paper
Sanjay S. Timilsina, XiuJun Li
A reusable and cost-effective paper-in-polymer-pond (PiPP) hybrid microfluidic microplate with unique features for ultrasensitive and high-throughput multiplexed detection of disease biomarkers within an hour without using specialized instruments.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Surface modification of paper-based microfluidic devices via initiated chemical vapor deposition

Lab Chip, 2024, 24,4940-4947
DOI: 10.1039/D4LC00414K, Tutorial Review
Stacey Bacheller, Malancha Gupta
Paper-based microfluidic devices offer a low-cost platform for biological and environmental detection. This tutorial review shows that initiated chemical vapor deposition can be used to modify these devices with functional polymers.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Rapid low-cost assembly of modular microvessel-on-a-chip with benchtop xurography

Lab Chip, 2024, 24,5065-5076
DOI: 10.1039/D4LC00565A, Paper
Open Access
Shashwat S. Agarwal, Marcos Cortes-Medina, Jacob C. Holter, Alex Avendano, Joseph W. Tinapple, Joseph M. Barlage, Miles M. Menyhert, Lotanna M. Onua, Jonathan W. Song
Our study is a novel implementation of xurography for multi-layer microfluidic device fabrication. We demonstrate the versatility of this approach by presenting several modular 3D vessel-matrix arrangements.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Applying Low Levels of Strain to Model Nascent Phenomenon of Retinal Pathologies

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00205A, Paper
Chase Paterson, Elizabeth Vargis
Age-related macular degeneration (AMD) is a leading cause of vision loss in the elderly. A better understanding of the mechanisms of the disease, especially at early stages, could elucidate new...
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

A gravity-driven tissue chip to study the efficacy and toxicity of cancer therapeutics

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00404C, Paper
Open Access
Pouria Rafsanjani Nejad, Astha Lamichhane, Prasiddha Guragain, Gary Luker, Hossein Tavana
A 96-well plate format, fully-automated multi-organ tissue chip array with gravity-driven flow for cancer research.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Impact of microchannel width on axons for brain-on-chip applications

Lab Chip, 2024, 24,5155-5166
DOI: 10.1039/D4LC00440J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katarina Vulić, Giulia Amos, Tobias Ruff, Revan Kasm, Stephan J. Ihle, Joël Küchler, János Vörös, Sean Weaver
Axon growth is influenced by the width and number of microchannels, with growth cone adaptability reaching its limit for constraints smaller than 350 nm. Tradeoffs between axon growth and control need to be made for neurofluidic devices.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Dual-drive acoustic micromixer for rapid nucleation and ultrafast growth of perovskite nanoparticles

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00721B, Paper
Zhifang Liu, Yuwen Lu, Wei Tan, Guorui Zhu
An acoustic micromixer driven by bubbles and sharp edges, controlling the nucleation and growth of perovskite nanoparticles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ap

Road safety class mandatory for driving licence applicants in Ernakulam from Dec. 2

“The sessions will include new road safety guidelines in keeping with advancements in automobiles and road construction and also amendments made to the Motor Vehicles Act in the recent past”




ap

CKCL, private players help fill gaps in non-biodegradable waste management in Ernakulam




ap

HC declines former Chief Secretary’s plea seeking exemption from personal appearance

Court exempts Palakkad Collector from personal appearance on condition that she will appear through virtual mode




ap

HC flays police inaction in clearing blockade to Thiruvananthapuram Corporation office




ap

Man accused of raping a tribal Odisha woman engaged as domestic help surrenders before police

Former managing director surrenders after raping tribal woman, sparking protests; accused hospitalised; case under investigation




ap

Seaplanes have potential to woo high-budget tourists to Kerala: Biju Prabhakar

Aviation Secretary says these amphibious aircraft can link tourism locales in the State. A seaplane will operate a trial service from Kochi International Marina to the Mattupetty dam in Munnar on Monday




ap

CM owes Oommen Chandy an apology for sabotaging seaplane project: Sudhakaran 




ap

HC allows medical termination of pregnancy of minor rape survivor

Division Bench passed the order while allowing an appeal filed against a single judge’s order declining permission. Medical board said that termination of pregnancy was most appropriate




ap

Seaplane arrives in Kochi backwaters for demo flight to Mattupetty Dam

Seaplane service will boost tourism by fostering new enterprises and creating job opportunities allowing holidaymakers to explore more destinations quickly, say Tourism Secretary




ap

Seaplane demo flight in Kochi draws mixed response




ap

HC tells authorities to prevent anti-social activities by other methods before resorting to KAAPA




ap

The great Indian leapfrog



  • R K Nair