Recent experiences with combustible gas releases in residential buildings have led to a proposal for NFPA Standards Development for locating combustible gas detectors and consensus on installation location requirements. NFPA is considering a proposed

While your home energy bill may have increased while you shelter in place, the planet’s overall energy use has taken a significant downturn. According to the International Energy Agency’s (IEA) first quarter report, global carbon emissions could be down by 8% this year, the biggest drop the agency has ever seen.[...]

This is an interview that has been a long time in the making, and it did look as if the current situation with the world in various states of lock-down might delay it even further. However, it was an absolute pleasure to have a Skype conversation with former Arsenal captain Cesc Fabregas on Friday night.

We talk about how his move to Arsenal came about. What was it like as a teenager leaving home to come live in London, and join a club at the height of its power and success under Arsene Wenger? That was a dressing room with some big names and even bigger personalities – how did a 16 year old deal with that? We chat about his time at the club, his development as a player and a person, Arsene Wenger as a coach and how he helped him, plus his departure in the summer of 2011, playing for Barcelona, the return to England, whether or not he could have come back to us and lots more.

Cesc is very open and honest throughout, and I'm hugely appreciative of the time he gave me for this podcast. I hope you enjoy it.

See acast.com/privacy for privacy and opt-out information.

Robert SASAKI has added a photo to the pool:

Robert SASAKI has added a photo to the pool:

I awake in my small room and slip out under the mosquito net that cocoons my bed. I know the layout so don't need to light a candle. My pack is ready where I left it last night I sling it over my shoulder and disappear into the equal darkness outside. Th

According to our Shiva Mahapurana one day Vishnu and Brahma had an argument over their superiority. Shiva appeared in front of them in the form of a raging fire and asked them to each find the tip of the fire. Whoever reaches the tip would be superior bet

The owner of a Las Vegas chapel where celebrity couples like Joe Jonas and Sophie Turner have gotten married is staying wedded to her business.

Scientists studying diamonds from deep within Earth’s mantle found evidence of a reservoir of rocks and gas that may be nearly as old as the planet itself.

Researchers used rabbits and antidepressants to search for a link between orgasm and ovulation in female mammals.

George Gascón pushed L.A. County Dist. Atty. Jackie Lacey into a runoff. His challenge is to show how his progressive policies can keep us safer.

Former Laker Pau Gasol is still rehabilitating from a foot injury that cost him the 2019-20 season. He has aspirations to play in the NBA and Olympics.

Danielle Conti, 43, used the pandemic as her personal piggy bank after allegedly stealing the charge card from 70-year-old widower Anthony Catapano while making her daily rounds at hard-hit Staten Island University Hospital North sometime in early April, authorities charge.

Alec Martinez won two Stanley Cups with the Kings over 11 seasons. Now, he's set to be moved to the Vegas Golden Knights for two draft picks.

It's hard imagining Las Vegas as a ghost town. Here's what streets look like since casino-resorts closed.

Adam Gase eyeing Gang Green’s 2020 schedule is the highlight of comedian Frank Caliendo’s latest parody video featuring one of his favorite topics ... the NFL.

Adam Gase eyeing Gang Green’s 2020 schedule is the highlight of comedian Frank Caliendo’s latest parody video featuring one of his favorite topics ... the NFL.

California on Monday sued two gasoline trading firms, alleging they took advantage of a 2015 refinery explosion in Torrance to improperly drive up the price at the pump.

Olympic figure skater Mirai Nagasu, who grew up in her parents' restaurant in Arcadia, is determined not to let the coronavirus close the family business.

The Chinese-owned carmaker from Sweden wants to add "sustainability" to its reputation for safety

RANGERS boss Steven Gerrard has played down his side’s chances of winning the league despite a stoppage-time winner in their season opener.

Woolpert, Inc. is a cutting-edge national architecture, engineering and geospatial (AEG) firm that delivers value to clients by blending engineering excellence with innovative technology and geospatial applications. Woolpert was recently certified as an Employer of Choice by Great Place To Work .

Kurt Koehler, founder and president of AlGalCo, shows his HOT (Hydrogen on Tap) system.

As of today, Las Vegas' Monte Carlo Casino Hotel remains closed pending the investigation of last week's fire and the impending repair work. At this time, reservations at the Monte Carlo are being moved to other MGM Mirage hotels. In addition, the Lance Burton show will be suspended for the time being and all tickets that have already been purchased will be refunded.

A chronology of key events

Key facts, figures and dates

Madagascar's President Andry Rajoelina has promised to release a prominent journalist who was detained after criticising his handling of the coronavirus pandemic.

Tanzania says it has received its first shipment of Madagascar's self-proclaimed, plant-based "cure" for coronavirus, despite warnings from the World Health Organisation that its efficacy is unproven.

RS Automotive will become the first service station in the nation to completely convert their equipment from offering gasoline to 100 percent electric power.

Las Vegas, Nevada

Madagascar

The Amateur Traveler talks to Hunter Hillegas author of the Vegas Mate iPhone app about Las Vegas. The Amateur Traveler has covered Las Vegas before but the city is constantly changing.

Hear about travel to Madagascar as the Amateur Traveler talks to Corinne Vale from reflectionsenroute.com about her travel to this island nation off southern Africa.

Brandon police officers are searching for a man who was caught on camera attempting to pump gas in his car – without prepaying.

Ekta Singh
Nov 1, 2012; 25:217-221
From Research to Practice

Do you know which main gases are contained in the composition of air? Under climate change and global warming, carbon dioxide ...

(Kobe University) Hydrogen is a possible next generation energy solution, and it can be produced from sunlight and water using photocatalysts. A research group from Kobe University has developed a strategy that greatly increases the amount of hydrogen produced using hematite photocatalysts. In addition to boosting the high efficiency of what is thought to be the world's highest performing photoanode, this strategy will be applied to artificial photosynthesis and solar water-splitting technologies via university-industry collaborations.

(Stony Brook University) In evolutionary terms, islands are the stuff of weirdness. It is on islands where animals evolve in isolation, often for millions of years, with different food sources, competitors, predators, and parasites...indeed, different everything compared to mainland species. As a result, they develop into different shapes and sizes and evolve into new species that, given enough time, spawn yet more new species.

(American Society of Agronomy) Researchers develop soil-gas diffusivity model based on two agricultural soils.

Carol Rees Parrish
Oct 1, 2007; 20:231-234
Nutrition FYI

Bokai Song
Apr 28, 2020; 0:RA120.001981v1-mcp.RA120.001981
Research

⁶⁸Ga-DOTATOC-PET/MRI (⁶⁸Gallium-DOTATOC-positron emission tomography/magnetic resonance imaging) combines the advantages of PET in the acquisition of metabolic-functional information with the high soft tissue contrast of MRI. Standardized uptake values (SUV) in tumors were suggested as a measure of somatostatin receptor expression. A challenge with receptor ligands is, that the distribution volume is confined to tissues with tracer-uptake, potentially limiting SUV quantification. In this study, different functional, three-dimensional (3D) SUV, apparent diffusion coefficient (ADC) parameters and arterial tumor enhancement were tested for the characterization of gastroendopancreatic neuroendocrine tumors (GEP-NET). Methods: For this single-center, cross-sectional study, 22 patients with 24 histologically confirmed GEP-NET lesions (15 men/7 women; median, 61 years, range, 43-81 years), who received hybrid ⁶⁸Ga-DOTA-PET/MRI examinations at 3T between January 2017 and July 2019 met eligibility criteria. SUVs, tumor-to-background ratios (TBR), the total functional tumor volume (TFTV), ADCmean and ADCmin were measured based on volumes of interest (VOI) and examined with receiver operating characteristic analysis to determine cut-off values for differentiation between low and intermediate grade GEP-NET. Spearman’s rank correlation coefficients were used to assess correlations between functional imaging parameters. Results: The ratio of PET-derived SUVmean and diffusion-weighted imaging (DWI)-derived ADCmin was introduced as a combined variable to predict tumor grade, outperforming single predictors. Based on a threshold ratio of 0.03 to be exceeded, tumors could be classified as grade 2 with a sensitivity of 86% and specificity of 100%. SUV and functional ADC values as well as arterial contrast enhancement parameters showed non-significant and mostly negligible correlations. Conclusion: As receptor density and tumor cellularity appear to be independent, potentially complementary phenomena, the combined PET/MRI ratio SUVmean/ADCmin may be used as a novel biomarker, allowing to differentiate between grade 1 and 2 GEP-NET.

Targeting tumor-expressed receptors using selective molecules for diagnostic, therapeutic or both diagnostic and therapeutic (theragnostic) purposes is a promising approach in oncological applications. Such approaches have increased significantly over the past decade. Peptides such as gastrin-releasing peptide receptors (GRPR) targeting radiopharmaceuticals are small molecules with fast blood clearance and urinary excretion. They demonstrate good tissue diffusion, low immunogenicity, and highly selective binding to their target cell-surface receptors. They are also easily produced. GRPR, part of the bombesin (BBN) family, are overexpressed in many tumors, including breast and prostate cancer, and therefore represent an attractive target for future development.

For oncological management or radiotherapy planning, reliable staging tools are essential. Recent development of quinoline-based ligands targeting cancer-associated fibroblasts demonstrated promising preclinical and clinical results. The current study aimed to evaluate the role of fibroblast activation protein inhibitors (FAPI)-positron-emission tomography (PET)/computed tomography (CT) for primary malignancies located within the lower gastrointestinal tract (LGT) as a very first clinical analysis. Methods: ⁶⁸Ga-FAPI-PET/CT was performed in a cohort of 22 patients with LGT including 15 patients with metastatic disease, 1 patient with suspected local relapse and 6 treatment-naïve patients. ⁶⁸Ga-FAPI-04 and ⁶⁸Ga-FAPI-46 uptake was quantified by standardized uptake values (SUV)max and (SUV)mean. After comparison with standard imaging, changes in tumor stage/ localization and (radio)oncological management were recorded. Results: The highest uptake of FAPI tracer was observed in liver metastases and anal cancer with a SUV_max of 9.1 and 13.9, respectively. Due to a low background activity in normal tissue, there was a high tumor-to-background ratio of more than 3 in most lesions. In treatment-naïve patients, TNM was changed in 50% while for patients with metastases new findings occurred in 47%. In total, FAPI-imaging caused a high, medium and low change of (radio)oncological management in 19%, 33% and 29%, respectively. For almost every patient undergoing irradiation, target volume delineation was improved by ⁶⁸Ga-FAPI-PET/CT. Conclusion: The present study demonstrated that both primary and metastatic LGT were reliably detected by ⁶⁸Ga-FAPI-PET/CT leading to relevant changes in TNM status and (radio)oncological management. ⁶⁸Ga-FAPI-PET/CT seems to be a highly promising imaging agent for the diagnosis and management of LGT, potentially opening new applications for tumor (re-)staging.