Interview with Philip Greenland, MD, author of Comparison of Novel Risk Markers for Improvement in Cardiovascular Risk Assessment in Intermediate-Risk Individuals. Summary Points:

• In comparison with other competing biomarkers and risk factors, coronary artery calcium (CAC) is currently the most potent risk marker of subclinical coronary heart disease (CHD).
• CAC was shown in several observational studies to improve the prediction of risk beyond traditional risk factors.
• In this JAMA paper, CAC outperformed various competing risk assessment markers among asymptomatic people at intermediate risk for CHD. Whether CAC should be used in routine clinical practice, however, is still a matter of personal opinion or further research.

Interview with Robert W. Haley, MD, author of Controlling Urban Epidemics of West Nile Virus Infection. Summary Points:

• Epidemics of West Nile neuroinvasive disease have become a serious medical and public health challenge that will be with us for the foreseeable future.
• Ultra low-volume aerial spraying of urban areas, guided by surveillance of mosquito trap positivity and human cases, is necessary and cost-effective to prevent chronic neurologic disability and death.
• Complete, accurate, and timely diagnosis of West Nile viral disease in an epidemic is vitally important to spare patients needless prolonged antimicrobial therapy and build support for public health control measures.

Interview with Nancy A. Rigotti, MD, author of Strategies to Help a Smoker Who Is Struggling to Quit. Summary Points:

• Treat tobacco use like the chronic disease that it is. Don't give up if your first few efforts do not succeed.
• Medications and brief counseling are each effective, but combining the two is most effective.
• Link your smokers to free national resources like the tobacco quit lines (1-800-QUIT-NOW). New noncombustible tobacco products are coming.

Interview with Laura N. Gitlin, PhD, author of Nonpharmacologic Management of Behavioral Symptoms in Dementia. Summary Points:

• Attending to behavioral symptoms is part of comprehensive dementia care and requires ongoing long-term management.
• Use 6 steps to systematically prevent, assess, manage, eliminate or reduce behavioral symptoms.
• Use combination of nonpharmacologic approaches.
• Keep trying—nonpharmacologic approaches are relatively adverse free.
• Create a health professional team to offset time needed for provision of nonpharmacologic approaches.

Interview with Robert H. Shmerling, MD, author of Management of Gout: A 57-Year-Old Man With a History of Podagra, Hyperuricemia, and Mild Renal Insufficiency. Summary Points:

• Risk factor modification: alcohol intake, excess weight, diet, medications (although overall impact on gout uncertain).
• Acute gout can be treated with NSAIDs, colchicine, corticosteroids, or a combination of these.
• Urate-lowering treatment to prevent attacks and tophi is appropriate for certain patients with gout. (In my opinion, allopurinol is the best initial choice to suppress uric acid.)
• Urate-lowering treatment should suppress uric acid to 6.0 mg/dL or less; allopurinol should start no higher than 100 mg/d but titrate up based on uric acid levels; it is common to require more than 300 mg/d.
• Concomitant prophylaxis (eg, low-dose colchicine, 0.6 mg/d) is appropriate for 6-9 months or longer.

Take home message:
We now have new therapies and guidelines for the treatment of gout. Appropriate use of therapeutics for gout—both new and old—will provide optimal outcomes for the increasing number of patients with this common disease.

Australia. Department of Agriculture and Water Resources, author, issuing body

Thom, Vivienne, author

Accused in a 2012 case of attacking the District Magistrate''s bungalow in Murshidabad, Minister of State for Railways Adhir Ranjan Chowdhury applied for an anticipatory bail Tuesday at a local court here.

Indian companies raised a total of Rs 2.81 lakh crore in fresh capital from equity and debt markets in the April-December period of 2012.

Government today said 2012 has been a bad year for FDI due to global economic slowdown and steps were being taken to increase its inflow.

Delays in environment clearances needs to be addressed on a fast-track basis for achieving coal production target of 795 MT during the current five year plan (2012-17), the Economic Survey said today.

Cargo traffic at ports during the six-month period ended September 2012 grew by just 1.8% to 455.8 million tonne due to decline in shipments handled at major ports, Economic Survey said today.

The cover itself shows that the main author of Economic Survey, 2012-13 is different from the one who penned pre-budget documents for the previous three years

Hayden Library - TA418.9.N35 N396 2012

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Hayden Library - TA418.9.N35 S967 2012

Barker Library - T174.7.N79 2012

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Hayden Library - TK7874.85.S474 2012

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Barker Library - TA444.F73 2012

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Barker Library - TA444.F53 2015

[U.K.] : 20th Century Fox, [2012]

Ion Audio shows off the Piano Apprentice and Guitar Apprentice at CES Unveiled.  These instruments feature an iPad dock and light up keys (or frets) that allow even a tone-deaf novice to learn piano, guitar or even drums.

The iNuke Boom from Behringer weighs 700 pounds and can pump out an almost illegal amount of decibels.

We talk to 50 Cent about his latest line of headphones, the wireless SMS Syncs.  These cans feature a built-in EQ and utilize Kleer technology for wireless audio.

As Wired's Gadget Lab reporters prepare for one final day of CES coverage, they take time to reflect on the most noteworthy trends and products they’ve covered at the show so far.

Esprit de Corps brings a Reggae love vibe to SXSW 2012.

Wired Design takes a look at the innovative projects at this years ICFF in New York City

In Rock Band: Blitz, Harmonix Music Systems takes away the instruments to present an all-new arcade-style addition to the Rock Band series.

Defend yourself against mutants as one post apocalyptic Moscow’s last remaining survivors in Metro: Last Light’s crafted single player experience.

Set in 2025, Call of Duty: Black Ops 2 sets you up against terrorists with seriously high tech weapons.

2K Games revives its classic strategy role playing game with the release of XCOM: Enemy Unknown.

Play as Death in this unique action/adventure installment of the Darksiders series.

Play as your favorite DC superheroes in Netherream Studios' Mortal Kombat style fighting game.

Swing through Manhattan as Spider-Man with refined controls and new camera angles in The Amazing Spider-Man.

Square Enix presents Sleeping Dogs, an open world crime drama set in the city of Hong Kong.

Transformers: Fall of Cybertron offers an original story, new characters, and all new multiplayer features.

Square-Enix offers refined mechanics, accessibility, and a new points system in its latest addition to the Hitman series.

And we're off! Comic-Con is just starting and if we're to judge by this video, already super awesome! Check out a glimpse of whats to come...

Indie makers show their goods at Comic-Con 2012.