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Lupin aims to be part of ‘first wave of generics’ on GLP-1 products: Nilesh Gupta

GLP-1 products going off patent in some markets includes popular Type-2 diabetes and weight-loss drug Ozempic




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PFC reports net profit of ₹7,215 Cr in Q2 FY25

The power and infrastructure sector lender’s consolidated total income rose to ₹25,755 croe in Q2FY25




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Asian Paints profit declines 43.7% to ₹693.7 crore in Q2

Asian Paints had logged a net profit of ₹1,232.39 crore during the July-September period a year ago




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Ashok Leyland sees a positive shift in the e-bus procurement market with reasonable bidding rates

Dheeraj Hinduja expressed confidence that these initiatives are helping establish a more stable and predictable framework for procuring electric vehicles, which will benefit the sector’s long-term growth




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ITC’s snack brand Bingo! Inks five-year partnership to promote Pickleball in India

This partnership, starts with the Bingo! World Pickleball Championship (WPC)




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Jubilant FoodWorks net profit dips, revenues rise 43 per cent

Consolidated revenue from operations jumped 42.8 per cent to ₹1,954.72 crore  




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Other income takes TVS SCS into profits

Improved business environment attributed to the turnaround




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Home-grown solutions to life’s little problems

Subashree has proved a home garden is all it takes to have good health, good looks and a good life




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Microencapsulation of broccoli sulforaphane using whey and pea protein: in vitro dynamic gastrointestinal digestion and intestinal absorption by Caco-2-HT29-MTX-E12 cells

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03446E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ali Ali Redha, Luciana Torquati, John R. Bows, Michael J. Gidley, Daniel Cozzolino
Sulforaphane-rich extract was prepared from broccoli. The extract was encapsulated with whey and pea protein isolates by freeze-drying. The products were characterised and assessed for in vitro bioaccessibility and bioavailability.
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Pentadecanoic acid (C15:0, PA) induces mild maternal glucose intolerance and promotes the growth of the offspring partly through up-regulating liver PPARα and MAPK signaling pathways

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03970J, Paper
Jun Wang, Shiqi Zheng, Ziying Li, Yimei Tang, Yanhua Huang, Junwen Wang, Rui Li, Jie Peng
1% PA can induce a mild decrease in the maternal glucose tolerance and lipolysis mainly by activated MAPK and PPARα signaling.
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The influence of magnesium and manganese cations on the chemical and bioactive properties of purple and green basil

Food Funct., 2024, 15,10644-10662
DOI: 10.1039/D4FO02820A, Paper
Izamara de Oliveira, Antonios Chrysargyris, Tiane C. Finimundy, Márcio Carocho, Celestino Santos-Buelga, Ricardo C. Calhelha, Nikolaos Tzortzakis, Lillian Barros, Sandrina A. Heleno
Effects of hydroponic cultivation with enriched concentrations of magnesium (+Mg), manganese (+Mn), combinations of +Mg and +Mn, or decreased concentrations of these minerals (control) on the chemical/bioactive attributes of basil, were investigated.
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Enhancement of the flavor and functional characteristics of cod protein isolate using an enzyme–microbe system

Food Funct., 2024, 15,10717-10731
DOI: 10.1039/D4FO02272F, Paper
Zheng-Fei Yan, Jia-Yu Chen, Jing Yang, Shuai Yuan, Xue-Yi Qiao, Bo Xu, Ling-Qia Su
Cod protein isolate was first debittered using Streptomyces canus aminopeptidase (ScAPase) and then deodorized through probiotic fermentation, showing the most substantial. These products showed the most substantial proliferation effect on probiotics.
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Biological effects and mechanisms of dietary chalcones: latest research progress, future research strategies, and challenges

Food Funct., 2024, 15,10582-10599
DOI: 10.1039/D4FO03618B, Review Article
Yun Liang Zhang, Shuang Jiao Sun, Li Zeng
Chalcones are widely distributed in food and have multiple biological activities; there are limitations and drawbacks in the application of dietary chalcones in food; future research strategies and key issues for dietary chalcones.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: A comparative study of the hypolipidemic effects and mechanisms of action of Laminaria japonica- and Ascophyllum nodosum-derived fucoidans in apolipoprotein E-deficient mice

Food Funct., 2024, 15,10913-10914
DOI: 10.1039/D4FO90102A, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Tian Liu, Xue Wang, Yan-Ming Wang, Feng-Rong Sui, Xue-Ying Zhang, Hai-Di Liu, Dong-Yue Ma, Xiao-Xiao Liu, Shou-Dong Guo
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Lacticaseibacillus paracasei 207-27 alters the microbiota–gut–brain axis to improve wearable device-measured sleep duration in healthy adults: a randomized, double-blind, placebo-controlled trial

Food Funct., 2024, 15,10732-10745
DOI: 10.1039/D4FO01684J, Paper
Open Access
Jinxing Li, Jincheng Zhao, Xiaolei Ze, Liang Li, Yapeng Li, Zhimo Zhou, Simou Wu, Wen Jia, Meixun Liu, Yun Li, Xi Shen, Fang He, Ruyue Cheng
Probiotics have been reported to exert beneficial effects on sleep through the gut–brain axis.
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Antigenotoxic and cosmetic potential of elderberry (Sambucus nigra) extract: protection against oxidative DNA damage

Food Funct., 2024, 15,10795-10810
DOI: 10.1039/D4FO03217A, Paper
Sara Gonçalves, Francisco Peixoto, Tayse F. F. da Silveria, Lillian Barros, Isabel Gaivão
The integrity of the genome is under constant threat from both endogenous and exogenous factors that induce oxidative stress and accelerate ageing.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Relationships of dietary habits with prostate cancer risk: results from Mendelian randomization analyses and the National Health and Nutrition Examination Survey

Food Funct., 2024, 15,10823-10837
DOI: 10.1039/D4FO03859B, Paper
Zhen Zhou, Jin Xu, Yang Zhao, Yuanjie Niu
Prior investigations identified correlations between dietary habits and the risk of prostate cancer (PCa); however, the causative dynamics are unclear.
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High-fat diet promotes type 2 diabetes mellitus by disrupting gut microbial rhythms and short-chain fatty acid synthesis

Food Funct., 2024, 15,10838-10852
DOI: 10.1039/D4FO02957G, Paper
Yangrui Wang, Fenfen Yan, Qingxue Chen, Fei Liu, Baofeng Xu, Yuanyuan Liu, Guicheng Huo, Jinsheng Xu, Bailiang Li, Song Wang
A schematic diagram of a high-fat diet promotes type 2 diabetes mellitus by disrupting gut microbial rhythms and short-chain fatty acid synthesis.
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Exploring the potential of sorghum with reference to its bioactivite, physicochemical properties and potential health benefits

Food Funct., 2024, Accepted Manuscript
DOI: 10.1039/D4FO04128C, Review Article
Sakshi Singh, Mehvish Habib, David J McClements, Khalid Bashir, Shumaila Jan, Kulsum Jan
Sorghum is a resilient and adaptable cereal grain recognized for its rich nutritional profile. It is a valuable source of dietary fiber (around 6%), protein (9-13%), and essential minerals such...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Summer–autumn tea promotes adipocyte browning and thermogenesis in association with gut microbiota regulation in high-fat diet-fed mice

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03826F, Paper
Chengcheng Yang, Luyao Liu, Yao Du, Lu Zhao, Lu Liu, Xingbin Yang, Yan Zhao
This study revealed for the first time the anti-obesity effect of summer–autumn tea aqueous extract (SATE) and its underlying mechanism.
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Gastroprotective effects of Pediococcus acidilactici GKA4 and Lactobacillus brevis GKL93 against ethanol-induced gastric ulcers via regulation of the immune response and gut microbiota in mice

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO04106B, Paper
Yun-En Huang, Sheng-Yi Chen, Tsung-Ju Li, You-Shan Tsai, Chin-Chu Chen, Gow-Chin Yen
Pediococcus acidilactici GKA4 and Lactobacillus brevis GKL93 exert gastroprotective effects against ethanol-induced gastric ulcers through multiple mechanisms.
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Anti-obesity and other health benefits of bioprocessed black rice bran in combination with green tea extract in 3T3-L1 preadipocyte cells and in mice on a high-fat diet

Food Funct., 2024, Accepted Manuscript
DOI: 10.1039/D4FO03210A, Paper
Ki Sun Kwon, Eun Seok Lee, Kyung Hee Lee, Woon Sang Hwang, Wha Young Lee, Jae Jung Kim, Jeanman Kim, Sang-Jong Lee, Sung Phil Kim, Mendel Friedman
Black rice bran, a waste product from the commercial milling of black rice that removes the bran and germ and leaves the starchy endosperm, contains bioactive anthocyanin, phenolic, and phytosteroid...
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Interaction of oat bran and exercise training improved exercise adaptability via alleviating oxidative stress and promoting energy homeostasis

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03374D, Paper
Rui Dong, Hamad Rafique, Qianwen Niu, Xin Zeng, Maria Cristina Messia, Li Yuan, Lin Shi, Liang Zou, Lu Li, Xinzhong Hu
Interaction of oat bran (OB) diet and moderate intensity exercise training (MlET) reinforced the positive effect on skeletal muscle function.
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Investigating serum concentration profiles of orally ingested short-chain fatty acid supplements

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO04028G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Christopher G. Green, Marilyn L. Y. Ong, Samantha N. Rowland, Tindaro Bongiovanni, Lewis J. James, Tom Clifford, Stephen J. Bailey, Liam M. Heaney
HPMC capsules containing acetate, propionate, and butyrate salts exhibit peak serum concentrations of each short-chain fatty acid within 60 min and a return to baseline within 120 min. Seven days of repeated intake does not alter basal serum levels.
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Preparation and characterization of white shrimp hydrolysate-xylooligosaccharides Maillard products and their in vivo promotive effects of zinc absorption in mice

Food Funct., 2024, Accepted Manuscript
DOI: 10.1039/D4FO03709J, Paper
Shijie Dou, Xuening Yu, Yuewen Xu, Xiaoyang Liu, Fawen Yin, Deyang Li, Da-Yong Zhou
The Maillard reaction products, as a kind of glycosylation-based reaction, possess the metal-chelating ability. In this study, the white shrimp hydrolysate (WH) and xylooligosaccharides (XOS) were used to prepare the...
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Characterisation and quantification of phenolic, anthocyanidin and terpene species in plant foods and plant food-based complementary products with antioxidant and neuroprotective properties

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO02942A, Paper
Naomi May, Jiahua Shi, Helen Clunas, Julianna Lys de Sousa Alves Neri, Celine Kelso, Jody Morgan, Yinghua Yu, Karen Charlton, Katrina Weston-Green
Phytochemicals, including phenolic compounds and terpenes, are of interest for the treatment and prevention of conditions with oxidative stress, inflammatory and neurodegenerative pathologies.
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A probiotic multi-strain mixture combined with hydroxyectoine improves intestinal barrier function by alleviating inflammation in lipopolysaccharide stimulated differentiated Caco-2 cells

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03130J, Paper
Azza Dabous, Antonietta Stellavato, Donatella Cimini, Valentina Vassallo, Maria D'Agostino, Chiara Schiraldi
Freeze-dried formula containing three probiotic strains and hydroxyectoine reduces LPS-induced inflammation in Caco-2 cells, assessed via RT-PCR, western blot, ELISA, and immunofluorescence for tight junction integrity.
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Impact of pH on the fabrication of egg white reinforced soy protein composite microgels for gastrointestinal delivery purposes

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03997A, Paper
Feng Liu, Yi Liu, Suyun Zhang, Gang Liu, Christos Ritzoulis, Yue Zhang
Protein molecules such as soy protein isolate (SPI) and egg white (EW) are highly promising materials for developing hydrogels (especially micro/nanogels) for the encapsulation, protection and controlled release of bioactive substances.
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Protein-bound AGEs derived from methylglyoxal induce pro-inflammatory response and barrier integrity damage in epithelial cells by disrupting the retinol metabolism

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO00364K, Paper
Gang Yu, Jianxin He, Zhongshan Gao, Linglin Fu, Qiaozhi Zhang
Protein-bound advanced glycation end-products (AGEs) induce pro-inflammatory response and barrier integrity damage in epithelial cells by disrupting the retinol metabolism.
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Immunomodulatory properties of hempseed oligopeptides in an LRRK2-associated Parkinson's disease animal model

Food Funct., 2024, 15,11115-11128
DOI: 10.1039/D4FO03167A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Maria Torrecillas-Lopez, Fernando Rivero-Pino, Paula Trigo, Rocio Toscano-Sanchez, Teresa Gonzalez-de la Rosa, Alvaro Villanueva, M. Carmen Millan-Linares, Sergio Montserrat-de la Paz, Carmen M. Claro-Cala
Hemp protein hydrolysate is capable of alleviating neuroinflammation by reducing the expression of pro-inflammatory cytokines, which could have promising effects in Parkinson's disease.
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Aronia melanocarpa extract extends the lifespan and health-span of Caenorhabditis elegans via mitogen-activated protein kinase 1

Food Funct., 2024, 15,11020-11035
DOI: 10.1039/D4FO02479F, Paper
Huan Zhang, Zhigang Zhu, Wenjing Wei, Zekun Liu, Huiji Zhou, Yueling Gong, Xinlei Yan, Jun Du, Houkai Li, Liang Chen, Lili Sheng
Aronia melanocarpa (AM) was shown to promote the lifespan and health-span of C. elegans via the PMK-1 pathway, highlighting the potential of AM as a dietary supplement for delaying aging.
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Dynamic changes in the gel properties, microbial community, and volatile flavor profile of Spanish mackerel (Scomberomorus niphonius) sausages inoculated with Lactiplantibacillus plantarum CY1-2

Food Funct., 2024, 15,11060-11071
DOI: 10.1039/D4FO03841J, Paper
Xinran Lv, Wenyu Wu, Shuilin Liu, Lili Ding, Anqi Ren, Le An, Fengling Bai, Jianrong Li, Xuepeng Li, Shumin Yi
This study aimed to examine the dynamic changes in the gel properties, microbial diversity, and volatile flavor compounds (VFCs) of Spanish mackerel sausages inoculated with Lactiplantibacillus plantarum CY1-2 during fermentation.
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Cardamonin protects against diabetic cardiomyopathy by activating macrophage NRF2 signaling through molecular interaction with KEAP1

Food Funct., 2024, 15,11083-11095
DOI: 10.1039/D4FO03543G, Paper
Wenshan Nan, Jialin Yin, Wenhao Hao, Huali Meng, Junduo Wu, Xiao Yin, Hao Wu
Cardamonin inhibited macrophage M1 polarization in diabetic cardiomyopathy by binding to KEAP1, leading to the dissociation of NRF2 from KEAP1. This promoted NRF2 nuclear translocation and antioxidant gene expression in M1 polarized macrophages.
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Metagenomic and transcriptomic profiling of the hypoglycemic and hypotriglyceridemic actions of Tremella fuciformis-derived polysaccharides in high-fat-diet- and streptozotocin-treated mice

Food Funct., 2024, 15,11096-11114
DOI: 10.1039/D4FO01870B, Paper
Xiaofei Xu, Xiaofei Liu, Liyan Liu, Jin Chen, Jingjing Guan, Donghui Luo
Tremella fuciformis polysaccharides exhibit hypoglycemic and hypotriglyceridemic activities through altering the taxonomic and functional attributes of the gut microbiota and modulating gene expression in the liver.
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Up-regulation of myelin-associated glycoprotein is associated with the ameliorating effect of omega-3 polyunsaturated fatty acids on Alzheimer's disease progression in APP–PS1 transgenic mice

Food Funct., 2024, 15,11236-11251
DOI: 10.1039/D4FO03355H, Paper
Yan Shao, Fei Li, Bo Zou, Yanling Jin, Xiaoyang Wang, Liting Wang, Youying Huang, Yu Xie, Wei Sun, Jing X. Kang, Kai Liu, Yi Huang, Wei Huang, Bin Wang
Our study showed that MAG upregulation might be the new regulatory mechanism for omega-3 PUFAs to exert AD protective effects, which is helpful for expanding our understanding of the health-promoting effects of omega-3 PUFAs.
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CoQ10 bioaccessibility and Caco-2 cell uptake improved with novel medium chain triglyceride encapsulation

Food Funct., 2024, 15,10981-10986
DOI: 10.1039/D4FO02844A, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ziqi Li, Rachel E. Kopec
Coenzyme Q10 (CoQ10), a key component of the electron transport chain, is better micellarized and absorbed by intestinal cells following novel encapsulation with MCTs + phospholipid.
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Techno-functional, antioxidant, and amino acid characterization of hydrolyzed bioactive peptides from coconut (Cocos nucifera L.) meal protein

Food Funct., 2024, 15,11266-11279
DOI: 10.1039/D4FO02741H, Paper
Roshanak Zolqadri, Zahra Akbarbaglu, Khashayar Sarabandi, Seyed Hadi Peighambardoust, Seid Mahdi Jafari, Amin Mousavi Khaneghah
In this study, the techno-functional characteristics and nutritional value of coconut meal protein (CMP) and the obtained polypeptides by alcalase (H-Alc), trypsin (H-Try), pancreatin (H-Pan), and pepsin (H-pep) were investigated.
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Allergenicity evaluation of an extensively hydrolyzed infant formula based on cow milk protein

Food Funct., 2024, 15,11036-11046
DOI: 10.1039/D4FO03582H, Paper
Hongbo Li, Lin Yang, Jiayi Li, Quan Gao, Tiantian Liu, Yang Zou, Xiaohong Chen, Hongjuan Li, Jinghua Yu
We developed an extensively hydrolyzed infant formula (EHF) with a protein composition similar to breast milk (whey protein-to-casein ratio of 6 : 4) and evaluated its sensitization in vitro and in vivo.
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Development of Pickering water-in-oil emulsions using a dual stabilization of candelilla wax and acylated EGCG derivatives to enhance the survival of probiotics (Lactobacillus plantarum) powder

Food Funct., 2024, 15,11141-11157
DOI: 10.1039/D4FO01342E, Paper
Zhaojuan Shi, Jun Wu, Xingting Wang, Tongqiao Nie, Qingmei Zeng, Chuanxun Yuan, Risheng Jin
Candelilla wax reinforced the stability of Pickering W/O emulsions with a three-dimensional crystal network. The oil phase volume fraction of the emulsions showed dramatic differences in protecting probiotic viability from environmental stresses.
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Alleviating effect of whey protein supplementation on oxidative stress in hypothyroidism

Food Funct., 2024, 15,11158-11168
DOI: 10.1039/D4FO03186E, Paper
Ann Liya Sajan, Jenat Pazheparambil Jerom, Bhagyasree Rajasekharan Nair, Devanandana Dileep Kumar Sajitha, Reshma Soman, Ajmal Jalal, Raveendran Harikumaran Nair
Supplementation with whey protein is effective for treating hypothyroidism-associated oxidative stress by enhancing the antioxidant system, reducing lipid peroxidation and maintaining cellular ionic balance.
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The co-fermentation of whole-grain black barley and quinoa improves murine cognitive impairment induced by a high-fat diet via altering gut microbial ecology and suppressing neuroinflammation

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO02704C, Paper
Fenfen Wei, Huibin Jiang, Chuang Zhu, Lingyue Zhong, Zihan Lin, Yan Wu, Lihua Song
A high-fat diet (HFD) is associated with various adverse health outcomes, including cognitive impairment and an elevated risk of neurodegenerative conditions.
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Ergothioneine improves cognitive function by ameliorating mitochondrial damage and decreasing neuroinflammation in a D-galactose-induced aging model

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO02321H, Paper
Fangyang Chen, Botao Wang, Xin Sun, Yage Wang, Ruiyan Wang, Kaikai Li
EGT intervention significantly improved D-galactose induced oxidative stress, neuroinflammation, and mitochondrial function, resulting in the alleviation of memory injury.
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Promote millets for nutritional security

Several studies show that consumption of millets reduce the risk of heart disease and have a positive impact on anaemia apart from controlling blood pressure




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How costly is it to produce money?

Cost-benefit analyses key to determining the features and designs that go into making various notes




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Understanding the election process: How is the US President elected?

While citizens cast their votes, the actual selection of the president is determined by the Electoral College




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Editorial. Property rights

SC ruling curtails untrammelled State powers




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Ethanol blending is proving messy

With a scramble for feedstock and the food-versus-fuel conflict, it needs impartial evaluation




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The Crown Review: Appropriate Finale

After the debacle of the first episodes of Season 6, the latter half give an even-handed treatment to intriguing not-so-well-known events of Queen Elizabeth II's reign, observes Vaihayasi Pande Daniel.




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Farmers in Punjab block highways in protest against 'tardy' paddy procurement




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Measures undertaken to ensure seamless paddy procurement in Punjab: Pralhad Joshi