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Swapping old ones for new




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Transition-metal-catalyzed regiodivergent sulfonylation of aziridrines for the synthesis of β-amino sulfones

Org. Chem. Front., 2024, 11,6340-6346
DOI: 10.1039/D4QO01376J, Research Article
Qinqiong Zeng, Yujia Gong, Xiaochun He, Xuemei Zhang, Zhong Lian
We developed the first transition-metal-catalyzed, regiodivergent sulfonylation of aziridines, enabling the efficient synthesis of diverse β-amino sulfones under mild conditions with broad substrate compatibility and high regioselectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chiral synthetic unprecedented spiro[indoline-2,3'-thiophen]-3-ones via an organocatalytic asymmetric sulfa-Michael/aldol cascade reaction

Org. Chem. Front., 2024, 11,6426-6436
DOI: 10.1039/D4QO01551G, Research Article
Mao Zhang, Xing-Hai Fei, Gui-Ping Yang, Cheng Lin, Wen-Jie Li, Ming-Liang Rao, Meng Zhou, Chong Zhao, Bin He, Yong-Long Zhao
A cinchona-derived squaramide-catalyzed asymmetric sulfa-Michael/aldol cascade reaction of 2-ylideneoxindoles with 1,4-dithiane-2,5-diol was developed to realize the chiral synthesis of spiro[indoline-2,3'-thiophen]-3-ones.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Asymmetric synthesis of (aza)flavanones by the evolution of CarOx ligands

Org. Chem. Front., 2024, 11,6444-6449
DOI: 10.1039/D4QO01345J, Research Article
Juan Yang, Wenlong Kong, Mingxin Chang, Jixing Lai, Shengkun Li
Amino-pyridine-oxazoline (NHPyOx) is conceived as an unprecedented model via the core-emulating optimization of CarOx ligands.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Carbonate-assisted selectively deoxygenative cross-coupling reaction between aryl and aliphatic aldehydes: a straightforward route to access α-alkylated aryl ketones

Org. Chem. Front., 2024, 11,6510-6517
DOI: 10.1039/D4QO01517G, Research Article
Yu Sun, Yi Wang, Zhijun Zuo
A novel reductive cross-coupling reaction of two different aldehydes for rapidly assembling α-alkylated aryl ketones has been developed. The inexpensive carbonate served not only as a base but also as an efficient electron donor.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Sulfenylation of bioactive maleimides, acrylates and cyclohexenones under ambient organophotocatalysis

Org. Chem. Front., 2024, 11,6503-6509
DOI: 10.1039/D4QO01342E, Research Article
Debanjana Bag, Rajjakfur Rahaman, Anindya S. Manna, Subhasis Pal, Rajesh Nandi, Shobhon Aich, Narendra Nath Ghosh, Dilip K. Maiti
A novel visible light-induced sulfenylation of biologically important maleimides, acrylates and cyclohexenones has been developed using cheap and easily available organophotoredox catalyst Eosin Y with thiols under ambient conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A two-step Kinugasa/Conia-ene-type sequential reaction for the asymmetric synthesis of 8-methylene-2,6-diazaspiro[3.4]octane-1,5-diones

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01388C, Research Article
Shanyue Li, Qicai Ma, Bohua Wu, Haowen Ma, Wei Zhou, Qian Cai
A two-step Kinugasa/Conia-ene-type sequential reaction is developed. The process provided a simple and efficient access to chiral 8-methylene-2,6-diazaspiro[3.4]octane-1,5-diones.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Facile single-step synthesis of pentaaryl-substituted pyrano[3,2-b]pyrrol-5(1H)-ones showing aggregation-induced emission

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01600A, Research Article
Yongfeng Wang, Ruijun Chu, Yanxiao Wang, Mengyuan Zhou, Yuan Chen, Cheng Xu, Jingyu Sun, Guodong Yin
A novel class of heterocyclic AIEgens has been synthesized via a multicomponent reaction of isatins, 2,3-diaryl cyclopropenones, and alkyl bromides.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Iridium-catalyzed asymmetric cascade allylation/lactonization of methyl salicylates: enantioselective construction of chiral benzodioxepinones

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01771D, Research Article
Bendu Pan, Yunru Wu, Yaqi Zhang, Xiaobo He, Long Jiang, Liqin Qiu
An efficient asymmetric cascade allylation/lactonization of methyl salicylates is achieved. The utilization of chiral-bridged biphenyl phosphoramidite ligand resulted in good results for the construction of a wide range of chiral benzodioxepinones.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o-bromobenzoic acids for the synthesis of fused isoquinolinones

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01573H, Research Article
Zhaolin Quan, Yubo Duan, Zhengkai Chen
A straightforward approach for the preparation of fused isoquinolinone derivatives via palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o-bromobenzoic acids is described.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Transition-metal-free skeletal editing of benzoisothiazol-3-ones to 2,3-dihydrobenzothiazin-4-ones via single-carbon insertion

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01714E, Research Article
Ke Yang, Qin Li, Yanqi Luo, Dan Yuan, Chunjian Qi, Zhengyi Li, Bijin Li, Xiaoqiang Sun
Transition-metal-free ring expansion of benzoisothiazol-3-ones has been established to construct various 2,3-dihydrobenzothiazin-4-ones via single-carbon insertion.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Influence of hydrogen bonds and π-π stacking on the self-assembly of aryldipyrrolidones

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01577K, Research Article
Open Access
Pedro Ximenis, Llorenç Rubert, Heike Ehmann, Bartolome Soberats
We report on the self-assembly behaviour in solution and solid-state of two newly designed bisdendronized aryldipyrrolidones (BDP and NDP) dyes with two free N-H at the lactam positions. Interestingly, while...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rhodium-catalyzed synthesis of N-substituted 3-acylpyrroles from enaminones and vinylene carbonate

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01816H, Research Article
Sheng-Jiao Yan, Jian-Bo Ma, Yi-Mai Yin, Xing-Mei Hu, Bi-Na Shao, Kun Huang, Qing-Sheng Zhao
Skeletal editing is a highly efficient strategy for modifying the core scaffolds of drug molecules, with multi-atomic editing as an emergent approach. Herein, we present a protocol for constructing N-substituted...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Mechanistic insights into rhodium-catalyzed C−H activation and annulation using vinyl acetate to access cinnolines and cinnolin-4(1H)-ones

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01734J, Research Article
Yuqin Wang, Yiling Zeng, Ya-Nan Tian, Zheng Liu, Jinhua Wang, Shuyou Chen, Shiqing Li
Transition metal-catalyzed C−H activation and annulation involving vinyl acetate remains a significant challenge, and the mechanistic process following vinyl insertion is ambiguous. Herein, we report the Rh(III)-catalyzed two-fold C−H activation...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A mild and convenient protocol for the synthesis of quinoxalin-2(1H)-ones and benzimidazoles

RSC Adv., 2024, 14,35386-35390
DOI: 10.1039/D4RA06887D, Paper
Open Access
Zhenbiao Luo, Mingyuan Wang, Guidong Jiang, Xinye Wang, Liang Zhao, Zhihui Hu, Honghe Li, Qing Ji
We present a mild and simple method for the cyclization of N-protected o-phenylenediamines with carbonyl compounds in the presence of trifluoroacetic acid.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Reaction of unsymmetrical α-bromo-1,3-diketones with N-substituted thioureas: regioselective access to 2-(N-arylamino)-5-acyl-4-methylthiazoles and/or rearranged 2-(N-acylimino)-3-N-aryl-4-methylthiazoles

RSC Adv., 2024, 14,35585-35600
DOI: 10.1039/D4RA05436A, Paper
Open Access
Ranjana Aggarwal, Shilpa Sharma, Naman Jain, Dionisia Sanz, Rosa M. Claramunt, Patricia Delgado, M. Carmen Torralba
Hantzsch's [3 + 2] cyclic condensation of α-bromo-1,3-diketones with N-substituted thioureas.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Volcanic eruption burns houses in Indonesia, killing at least 9 people

Authorities raised the danger level and widened the danger zone for Mount Lewotobi Laki Laki on Monday, following a series of eruption that last week




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How to Will your assets to loved ones

In the absence of a Will, succession laws decide who will inherit your estate




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15 missing in Indonesia boat accident

After a speedboat collided with a Vietnamese cargo vessel




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Watch | Largest ever recorded tanzanite gemstones found




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Focus on food and energy crisis due to Ukraine war, says Indonesian President Joko Widodo

Mr. Joko says he is ready to help with Modi-Xi meeting at the G20




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U.K. PM race | At debate, Truss says she will call out Putin in front of “swing” countries like India, Indonesia

Sunday’s debate was the second in the U.K. Prime Ministerial race that began last week, with a third round of voting set for Monday




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I was raised by one family, but I think it represents so many of our families: Priyanka Mattoo, author of Bird Milk and Mosquito Bones

Priyanka Mattoo on her journey across countries, and why she sees herself as the ‘megaphone’ for a culture




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A safe and new strategy for N-arylation of 2,4-thiazolidinediones via microwave irradiation using base catalyst K2CO3 in DMF

React. Chem. Eng., 2024, 9,842-848
DOI: 10.1039/D3RE00641G, Paper
Ragini C. Patil, Nita M. Khiratkar, Sumeer Ahmed, Joazaizulfazli Jamalis, Aso Hameed Hasan, Malika Berredjem, Sarkar M. A. Kawsar, Ajmal R. Bhat
Green efforts as an alternative to existing conventional methods for providing new tools, knowledge and design of organic synthesis, will contribute to the economy and protecting the environment and health.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Biological effects and mechanisms of dietary chalcones: latest research progress, future research strategies, and challenges

Food Funct., 2024, 15,10582-10599
DOI: 10.1039/D4FO03618B, Review Article
Yun Liang Zhang, Shuang Jiao Sun, Li Zeng
Chalcones are widely distributed in food and have multiple biological activities; there are limitations and drawbacks in the application of dietary chalcones in food; future research strategies and key issues for dietary chalcones.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lacticaseibacillus paracasei JM053 alleviates osteoporosis in rats by increasing the content of soy isoflavone aglycones in fermented soymilk

Food Funct., 2024, Accepted Manuscript
DOI: 10.1039/D4FO04381B, Paper
Yaping Zheng, Shasha Cheng, Hongxuan Li, Yilin Sun, Ling Guo, Chaoxin Man, Yu Zhang, Wei Zhang, Yujun Jiang
Lacticaseibacillus paracasei JM053 has a high ability to convert soy isoflavones and can be used as a fermentation strain to ferment soymilk, thereby increasing the content of free aglycones in...
The content of this RSS Feed (c) The Royal Society of Chemistry




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UAS-B’s Krishi Mela on theme ‘climate-smart digital farming’ to feature drones for coconut-plucking, AI-based farm machinery

The Krishi Mela will be held on the GKVK campus of UAS-B from November 14 to 17




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Yemen’s Houthi rebels launch drones and missiles at U.S. warships near the Red Sea but do no damage

Pentagon press secretary said the Iranian-backed Houthis launched at least eight drones, five anti-ship ballistic missiles and three anti-ship cruise missiles at the USS Stockdale and the USS Spruance




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Doctor G: Lazy, Dishonest, Film

Doctor G is outwardly all for women, but evidently has no interest in them, observes Sreehari Nair.




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Sci-Five | The Hindu Science Quiz: On Drones

This week’s Sci-Five quiz is on drones.




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From vacuum cleaners to headphones, Dyson’s legacy of innovation continues

Mark Heard, engineering manager at Dyson on how and why the brand has journeyed from vacuum cleaners towards styling products and now headphones.




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Drones used for spraying larvicide to check mosquitoes in Vizag




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What Makes Kantara, Brahmastra The 'Chosen Ones'?

As much as we enjoy and write reams and reams about our amazement at the Kantara climax, 30 years on from now, will we remember these portions more fondly or the ones where Shiva is simply hanging out with his friends, mulls Rohit Sathish Nair.




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Biblia. Concordantiae in eadem, ex tum Veteri, tum Nouo Testamento, sacrisq[ue] canonibus: necnon & ex uiginti Iosephi De antiquitatibus, & Bello Iudaico libris excerptae. Annotationes ex sacris scriptoribus sumptae, & suis quaeq[ue] locis, &a

Lugduni : apud Hugonem à Porta, M. D. X L VI. [1546]




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Chennai| Thamalli, a newly launched bespoke jewellery brand features rare gemstones from around the world

Young entrepreneur Adithi Ganeshan speaks about her newly launched jewellery brand Thamalli, the design process, and working with rare gemstones



  • Life & Style

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Between the stones, there is no binding

An architectural marvel is tucked away in the folds of forests and peaks near Panaji in Goa.




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Nokia launches eco-friendly smartphones, subscription service Circular

Nokia also introduced three smartphones and a tablet



  • Mobiles & Tablets

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Apple maintains prices on new iPhones despite inflation

New iPhone14 models to boast better cameras, faster processors and a longer lasting battery




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Samsung to make premium Galaxy S23 smartphones in India

The development comes a day after Finance Minister Nirmala Sitharaman announced removal of duty on import of camera lens




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Apple releases new fixes for iPhones, Macs

Apple releases iOS 16.3.1, iPadOS 16.3.1, and macOS Ventura 13.2.1 updates



  • Mobiles & Tablets

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Foxconn to start manufacturing iPhones in Karnataka by April 2024

The company has already paid 30% of the land cost to the Karnataka Industrial Areas Development Board




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Realme launches 11 Pro Series 5G smartphones starting at ₹23,999

Realme has introduced two smartphones — the 11 Pro+ 5G and the 11 Pro 5G — under the flagship.



  • Mobiles & Tablets

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Apple's new iPhones get faster chips, better cameras and new charging ports

All the new models will be available in stores from September 22, with pre-orders beginning this Friday




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Local value addition in ‘Made in India’ smartphones climbs 16% in 2023

Samsung’s high local value add in comparison to Apple is largely a function of time




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Google to launch India-made Pixel 8 phones in 2024

Google partnering with international, domestic manufacturers to produce Pixel smartphones locally



  • Mobiles & Tablets

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Samsung to kick off year of AI phones with new launch this month

Likely to be known as the Galaxy S24, Samsung Electronics said it plans to launch its next flagship device on January 17 in San Jose, California




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Samsung launches newest Galaxy S24 smartphones with AI functions

Samsung looks to take on Apple with their latest AI functions in the S24 range.




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Samsung expects 75% of total handset sales to come from 5G smartphones in 2024

Announces the launch of Galaxy A55 5G and Galaxy A35 5G



  • Mobiles & Tablets

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Samsung enhances security features in its mid-segment smartphones

Samsung Knox Vault Security that was available in S series models, now features in A series smartphones



  • Mobiles & Tablets

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Average selling price of smartphones in first quarter in India stagnates for first time in three years: Report

The average selling price of smartphones remained flat YoY and QoQ at $263, ending a rising streak that lasted several quarters, IDC said