CSU Chancellor Timothy P. White and the presidents of the Northridge and East Bay campuses say they will stay on through fall 2020.

L.A school officials say the school year will start Aug. 18, but they plan to take a cautious path forward to reopening campuses as worries persist over health and safety concerns amid the coronavirus outbreak.

In a rare bit of reasonable regulatory activity by the Trump administration, new rules governing sexual assault accusations at colleges strike the right balance -- for the most part.

Designer Kathryn Ireland shares an insider's tricks of the trade with a select few over a jam-packed weekend.

Actor Larry Joe Campbell of "According to Jim" has sold his longtime home in Rancho Palos Verdes for $2.138 million.

Los Angeles area artists are taking advantage of Bandcamp's COVID-19 initiative, which gives musicians 100% of sales. Here are a few recommendations.

US campaign financing rules have been relaxed even further in recent years, making a worrying problem about the state of American democracy worse (because those with money have even more ability to try and buy votes or influence policy).

Media coverage of this issue, though it may pop up from time to time, seems quite limited. Perhaps because it is estimated that television stations this year could make as much as eight billion dollars from political campaigns.

The state of US mainstream media has unfortunately been lamentable for many years, and after the issues around hurricane Katrina, it was thought that the media would be rejuvenated. Unfortunately it does not seem that way.

This page has been updated with further information about campaign financing issues and how limits in the US have been lifted making the problem worse. Also added were notes on US press freedom, and an info graphic on media ownership concentration.

Read full article: Media in the United States

Stuart Lancaster spoke to Daily Express Chief Sports Writer about his season with Leinster.

BREXIT was almost thwarted before it could even begin as former Prime Minister David Cameron planned legislation that could have significantly damaged Vote Leave's referendum campaign, a book claims.

BREXIT was almost thwarted before it could even begin as former Prime Minister David Cameron planned legislation that could have significantly damaged Vote Leave's referendum campaign, a book claims.

Keeping him in office prevents the left from destroying America with their socialistic ideology, a letter to the editor says.

Republican state Sen. Victoria Spartz had the biggest personal loan, giving her campaign $750,000 while raising under $10,000.

Watch Gary Varvel's time lapse video of of negative political campaign commercials.

Many voters are turned off by political attacks.

Colleges across Indiana are navigating how to handle refunds for students who have had to vacate residence halls during the COVID-19 pandemic.

Republican state Sen. Victoria Spartz had the biggest personal loan, giving her campaign $750,000 while raising under $10,000.

A lawyer who served as legal counsel for Mother Teresa told Republican Chuck Dietzen to stop using Mother Teresa's name and image in ads.

Mike Pence will visit Kokomo Thursday to highlight the administration's response to the novel coronavirus pandemic.

Florida attorney Jim Towey, who represented Mother Teresa for over a decade, said he regrets using her image in a 2016 ad for a U.S. House candidate.

Woody Guthrie Center will honor John Mellencamp's career of spotlighting "the everyday man and woman, the less fortunate and the forgotten."

It's no secret that university presidents are wringing their hands about decreased enrollment and lost tuition revenue because of coronavirus.

We here at Patriot Depot have mastered the art of creating the perfect cup o' joe: no cream, no sugar, and one Donald. (You can alter the first two according to taste.)

You will brew the perfect cup of coffee with..

Price: $14.95

The Members team ultimately fell 10-4 to the press team, despite valiant efforts from players such as 2020 presidential hopeful and team pitcher Kirsten Gillibrand.

Low-key no longer: The presidential candidate and his actress girlfriend appeared together at public events over the holiday weekend.

The rapper has been a supporter of the Democratic presidential candidate, and says she wants to help "a movement of young people to transform this country."

Obviously, due to the recent COVID-19 outbreak, summer plans are on hold until further notice. And for families who rely on camp during the warmer months, this can be problematic. Although traditional summer camps might be out of the question this year, there are plenty of virtual options that will keep kids of all ages entertained. Whether they're looking to keep their academics sharp (hey, no one likes that pesky summer slide, right?) or just want some good, old-fashioned fun, these online summer camps will deliver.

The Assad government sought to promote regime-sponsored cultural events through a marketing campaign called "Summer in Syria," but the effort didn't exactly go as planned.

At least 65,116 individuals have been "forcibly disappeared" by the Syrian government, according to a new report by Amnesty International.

From better campsite cooking to car maintenance to smartphone-free communication, here are 12 gadgets to up your car camping game.

The post Up Your Car Camping Game with These 12 Clever Gadgets appeared first on Vagabondish.

People are always curious about work-from-home (WFH), remote working setups. So, I posted a Basecamp message asking our employees to share a photo of their home office, desk, table, whatever. Here’s what came in. First, the ask: And the answers, in the order they came in: Andy Didorosi, Marketing Justin White, Programmer Jonas Downey, Designer… keep reading

David and I spent nearly 2-hours giving a livestream tour of our very own Basecamp account. We wanted to show you how Basecamp uses Basecamp to run projects, communicate internally, share announcements, know what everyone’s working on, build software, keep up socially, and a whole bunch more. Our entire company runs on Basecamp, and this… keep reading

We’ve been teaching people how to do remote work well for the better part of two decades. We wrote a whole book about the topic in 2013, called REMOTE: Office Not Required. Basecamp has been a remote company since day one, and our software is sold as an all-in-one toolkit for remote work. Yeah, we’re… keep reading

With the eviction date looming for campers to leave Oppenheimer Park, B.C.'s social development minister says everyone is still expected to be out of the park by Saturday.

Heat shock factor 1 (HSF1) regulates cellular adaptation to challenges such as heat shock and oxidative and proteotoxic stresses. We have recently reported a previously unappreciated role for HSF1 in the regulation of energy metabolism in fat tissues; however, whether HSF1 is differentially expressed in adipose depots and how its levels are regulated in fat tissues remain unclear. Here, we show that HSF1 levels are higher in brown and subcutaneous fat tissues than in those in the visceral depot and that HSF1 is more abundant in differentiated, thermogenic adipocytes. Gene expression experiments indicated that HSF1 is transcriptionally regulated in fat by agents that modulate cAMP levels, by cold exposure, and by pharmacological stimulation of β-adrenergic signaling. An in silico promoter analysis helped identify a putative response element for activating transcription factor 3 (ATF3) at −258 to −250 base pairs from the HSF1 transcriptional start site, and electrophoretic mobility shift and ChIP assays confirmed ATF3 binding to this sequence. Furthermore, functional assays disclosed that ATF3 is necessary and sufficient for HSF1 regulation. Detailed gene expression analysis revealed that ATF3 is one of the most highly induced ATFs in thermogenic tissues of mice exposed to cold temperatures or treated with the β-adrenergic receptor agonist CL316,243 and that its expression is induced by modulators of cAMP levels in isolated adipocytes. To the best of our knowledge, our results show for the first time that HSF1 is transcriptionally controlled by ATF3 in response to classic stimuli that promote heat generation in thermogenic tissues.

This article is by L. James Rice.

Campfire Pro is a program that aims to be a comprehensive tool for worldbuilders, ranging from authors to game designers to TTRPG Gamemasters, which means it’s got many features to explore. With that in mind, it’s probably best to give a little overview of the product before delving into its details.

First off, between gaming, screenwriting, and writing in general, I’ve seen a lot of these sorts of programs over the years and been disappointed by them more often than not. Campfire’s user interface harkens back to many older programs, keeping things relatively simple, and if you’re looking flashy bells and whistles, they aren’t here. You can, however, beautify the background with a variety of themes as well as create your own. Where this program excels is in its most important aspect, functionality, while for me at least, the biggest downfall is a less than intuitive interface. This could just be my brain, results will vary, but don’t be surprised by a tiny learning curve and the occasional “good grief, did I really just do that?” This is more about little irritants than deal breakers, however, and a little tinkering tends to find answers.

Continue reading Review of Campfire Pro Writing Software at Mythic Scribes.

ssm euromicron GmbH, a system house subsidiary of euromicron AG, is involved in a project to provide the technical equipment for the new building for the Institute of Geosciences at Kiel’s Christian Albrechts University. The seven-story new building is part of a campus-wide modernization initiative that is one of the largest public high-rise projects in the federal state of Schleswig-Holstein.

Heat shock factor 1 (HSF1) regulates cellular adaptation to challenges such as heat shock and oxidative and proteotoxic stresses. We have recently reported a previously unappreciated role for HSF1 in the regulation of energy metabolism in fat tissues; however, whether HSF1 is differentially expressed in adipose depots and how its levels are regulated in fat tissues remain unclear. Here, we show that HSF1 levels are higher in brown and subcutaneous fat tissues than in those in the visceral depot and that HSF1 is more abundant in differentiated, thermogenic adipocytes. Gene expression experiments indicated that HSF1 is transcriptionally regulated in fat by agents that modulate cAMP levels, by cold exposure, and by pharmacological stimulation of β-adrenergic signaling. An in silico promoter analysis helped identify a putative response element for activating transcription factor 3 (ATF3) at −258 to −250 base pairs from the HSF1 transcriptional start site, and electrophoretic mobility shift and ChIP assays confirmed ATF3 binding to this sequence. Furthermore, functional assays disclosed that ATF3 is necessary and sufficient for HSF1 regulation. Detailed gene expression analysis revealed that ATF3 is one of the most highly induced ATFs in thermogenic tissues of mice exposed to cold temperatures or treated with the β-adrenergic receptor agonist CL316,243 and that its expression is induced by modulators of cAMP levels in isolated adipocytes. To the best of our knowledge, our results show for the first time that HSF1 is transcriptionally controlled by ATF3 in response to classic stimuli that promote heat generation in thermogenic tissues.

The presumptive Democratic presidential nominee Joe Biden campaigns virtually in his Delaware home; Fox News correspondent Peter Doocy reports.