tribute Creating Leader Standard Work (LSW) Across a Distributed Business Model — Webinar Preview By www.leanblog.org Published On :: Thu, 07 Nov 2024 11:16:00 +0000 I'm happy to be hosting and moderating this webinar that will be presented by Brent Loescher, a fellow instructor with me at TKMG Academy. A Lean practitioner at heart, Brent received his formal Toyota Production System training while working for Toyota Motor Sales in their North American Parts Operations. He helped develop a Lean program for the landscape maintenance industry, implementing and evolving continuous improvement programs across the country since 2009. This included co-leading a […] The post Creating Leader Standard Work (LSW) Across a Distributed Business Model — Webinar Preview by Mark Graban appeared first at Lean Blog. Full Article Blog Change KaiNexus Leader Standard Work Webinar
tribute Canadian Blood Services discovery research lab contributes to new knowledge on neutrophils By www.blood.ca Published On :: Thu, 29 Aug 2024 14:37:37 +0000 Canadian Blood Services discovery research lab contributes to new knowledge on neutrophils Plasma Transfusion Blood Thursday, August 29, 2024 Abby Wolfe Dr. Donald R. Branch’s work as a discovery scientist at Canadian Blood Services focuses on immunotherapy, seeking to further enhance understanding of the cellular and molecular mechanisms involved in autoimmune diseases. Based in Toronto, Dr. Branch’s laboratory develops models of rheumatoid arthritis, Alzheimer’s disease, immune thrombocytopenia (ITP) and multiple sclerosis in mice. These models are particularly useful in examining how cells affected by these conditions respond to current therapeutic agents like intravenous immunoglobulin – a blood product made from human plasma commonly known as IVIg – and investigating potential alternative therapeutics. Over the years, Dr. Branch’s lab research findings have included the discovery of a special reagent that makes identification of antibodies easier by “zapping" autoantibodies, answers around unexpected side effects of IVIg therapy, and insights around recipients’ responses to bone marrow transplantation. It has also earned him numerous awards and accolades, including four from AABB, the Association for the Advancement of Blood & Biotherapies. Dr. Don Branch, Canadian Blood Services senior scientist New knowledge about neutrophils Recently, contributions from Dr. Branch’s lab helped a U.K.-based team of researchers discover new information about how neutrophil function and activity is regulated. Neutrophils are a type of white blood cell that are part of the body’s normal immune response. A person’s neutrophil levels may be affected by infections as well as chronic or acute illnesses. Patients who have very low neutrophil counts and/or persistent infections may receive a boost to their neutrophil levels via granulocyte transfusion therapy. However, in some diseases, overactivation of neutrophils can also create an inflammatory environment and harm healthy tissue. The research has been published in the high-impact scientific journal, Nature. This publication has filled a gap in knowledge about the mechanisms involved in maintaining balance between neutrophils’ infection-fighting power and inflammation-causing potential. As Dr. Branch describes: “This research by Dr. Brown and team shows that the myeloid inhibitory C-type lectin enzyme, which is known as MICL, controls neutrophil activity in rheumatoid arthritis. It is likely that MICL also regulates neutrophil activity in general. This suggests that if therapeutics can be designed to target MICL, they may be useful in controlling inflammation and infection. It is a fundamental finding that will change our understanding of the biology of neutrophils.” Discovery research, like the study to which Don and Ruqayyah contributed, is essential to improving patient care in the long run. New biomedical insights are essential to crafting new drugs and new therapeutic approaches in a rational way. Dr. William (Bill) Sheffield, Canadian Blood Services senior scientist and associate director of research Discovery research expertise leads to new collaboration The special mouse model that Dr. Branch’s lab uses is known as K/BxN. In this model, two mouse populations are selectively bred to produce offspring whose genetic material carry an antibody that destroys bone cartilage. An arthritis-causing serum containing this destructive antibody can then be obtained from the mice for use as a reagent in research. This process is termed “serum-transfer arthritis” and has been used by many investigators in the study of treatments that may alleviate the condition. Knowledge of Dr. Branch’s lab’s expertise in this area prompted a connection to the team of researchers at the Universities of Exeter and Aberdeen in the U.K. for this study. Says Dr. Branch, “In 2021, I supported a successful application to Canadian Blood Services’ Blood Efficiency Accelerator Program (BEAP) by Dr. Maria Fernandes, a researcher from Héma-Québec who works with neutrophils. Through this collaboration, Dr. Fernandes was aware that I work on rheumatoid arthritis with K/BxN mice, and she also knew that Dr. Gordon Brown in the U.K. was looking to collaborate with a researcher in this area for some planned neutrophil research. My lab, which included postdoctoral fellow Dr. Ruqayyah Almizraq at the time, contributed to Dr. Brown’s research by providing the sera from our K/BxN mice. With this sera, Dr. Brown and his collaborators were able to induce rheumatoid arthritis and show that it could be resolved by removing the inhibition of a specific enzyme.” Science that is never boring The Branch lab is currently using these same mouse models to investigate whether a recombinant protein called IgG1 Fc hexamer could be an effective replacement for IVIg in the treatment of autoimmune conditions like rheumatoid arthritis and ITP. While early results are promising, continued work is needed. In fact, back in 2018, Dr. Branch was asked in a previous R.E.D. blog post to describe what he found to be the most exciting part of science. Reflecting on the same question now, he reiterates that his response still rings true after 50 years in the field: The most exciting part of science is that when you do good science, you get more questions than you get answers, which means it is never boring. There is no end to imagination; new ideas, theories, experiments and discoveries occur often and provide a level of excitement to which many other professions cannot attest. Dr. Donald (Don) Branch, Canadian Blood Services senior scientist Canadian Blood Services – Driving world-class innovation Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact. The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency. Related blog posts Senior scientist wins prestigious award for discovering a ‘gold standard’ reagent used in transfusion medicine Tuesday, March 28, 2023 Aldis Brennan Dr. Donald Branch, Canadian Blood Services senior scientist, has received the Dale A. Smith Memorial Award for his discovery of the ZZAP reagent. This award, from the Association for the Advancement of Blood & Biotherapies (AABB), recognizes the application of technology to the practice of transfusion medicine or biotherapies. Transfusion Blood Read full story, Senior scientist wins prestigious award for discovering a ‘gold standard’ reagent used in transfusion medicine Interactive lab tour helps undergraduate students learn from Canadian Blood Services senior scientist and team Thursday, March 16, 2023 Beth Binnington, Senior Research Assistant Students from the Undergraduate Pathology Alliance at Western University posed insightful questions to researchers during an interactive visit to the research laboratory of Dr. Donald Branch, Canadian Blood Services senior scientist in February 2023. Plasma Transfusion Blood Read full story, Interactive lab tour helps undergraduate students learn from Canadian Blood Services senior scientist and team Meet the researcher: Dr. Donald Branch Wednesday, February 28, 2018 Dr. Kendra Hodgkinson For this instalment of “Meet the researcher”, we met with Dr. Donald Branch, a scientist at Canadian Blood Services who studies infectious diseases and immunology. How long have you been with Canadian Blood Services? I started with the Canadian Red Cross at the Edmonton Blood Centre in December 1985... Plasma Transfusion Blood Read full story, Meet the researcher: Dr. Donald Branch Full Article
tribute Episode 63: A Pattern Language for Distributed Systems with Henney and Buschmann By feedproxy.google.com Published On :: Wed, 25 Jul 2007 22:00:00 +0000 In this Episode we talked about the new POSA 4 book which has recently been published. We talk to two of the authors, Kevlin Henney and Frank Buschmann (the third author, Doug Schmidt was not available - and he had also been on the podcast a couple of times :-)). The book contains a pattern language for distributed systems. It contains 114 patterns that had been published before by many different other authors. The patterns have been rewritten to form a consistent language. We basically talked through the different sections of the book, which gives a really good overview over the challenges and the solutions of building distributed systems. These sections include From Mud to Structure, Distribution Infrastructure, Event Demultiplexing and Dispatching, Interface Partitioning, Component Patitioning, Application Contrl, Concurrency, Synchronization, Object Interaction, Adaptazion and Extension, Modal Behaviour, Resource Management and finally, Database Access. The book references several other previous works (as listed below). Interestingly, many of these referenced works and authors have also been discussed previously on the podcast. Here are the back references: Domain Driven Design, Eric Evans Messaging Patterns, Gregor Hohpe POSA 2 Patterns, Doug Schmidt Concurrency: Part 1, Part 2, Part 3 and the interview with Goetz and Holmes Remoting Patterns Part 1 and Part 2 POSA3, Resource Management Full Article
tribute Episode 181: Distributed Scrum with Rini van Solingen By www.se-radio.net Published On :: Wed, 07 Dec 2011 03:59:45 +0000 In this episode we talk with Rini van Solingen about scrum and agile software development in distributed settings. Full Article
tribute Episode 203: Leslie Lamport on Distributed Systems By www.se-radio.net Published On :: Tue, 29 Apr 2014 15:48:52 +0000 Leslie Lamport won a Turing Award in 2013 for his work in distributed and concurrent systems. He also designed the document preparation tool LaTex. Leslie is employed by Microsoft Research, and has recently been working with TLA+, a language that is useful for specifying concurrent systems from a high level. The interview begins with a […] Full Article
tribute Episode 229: Flavio Junqueira on Distributed Coordination with Apache ZooKeeper By traffic.libsyn.com Published On :: Tue, 16 Jun 2015 22:53:02 +0000 Full Article
tribute SE-Radio Episode 241: Kyle Kingsbury on Consensus in Distributed Systems By traffic.libsyn.com Published On :: Tue, 03 Nov 2015 17:46:47 +0000 Full Article
tribute Camille Fournier on Real-World Distributed Systems By traffic.libsyn.com Published On :: Tue, 19 Jul 2016 17:24:06 +0000 Stefan Tilkov talks to Camille Fournier about the challenges developers face when building distributed systems, whether the can avoid building them at all, and what changes occur once they do. Full Article
tribute SE-Radio-Episode-282-Donny-Nadolny-on-Debugging-Distributed-Systems By traffic.libsyn.com Published On :: Tue, 14 Feb 2017 21:03:32 +0000 Donny Nadolny of PagerDuty joins Robert Blumen to tell the story of debugging an issue that PagerDuty encountered when they set up a Zookeeper cluster that spanned across two geographically separated datacenters in different regions. Full Article
tribute SE-Radio Episode 285: James Cowling on Dropbox’s Distributed Storage System By traffic.libsyn.com Published On :: Tue, 14 Mar 2017 17:50:05 +0000 James Cowling of Dropbox tells Robert Blumen about their massive migration from Amazon’s S3 to their own distributed storage system. Full Article
tribute SE-Radio Episode 337: Ben Sigelman on Distributed Tracing By se-radio.net Published On :: Tue, 11 Sep 2018 16:45:40 +0000 Ben Sigelman CEO of LightStep and co-author of the OpenTracing standard discusses distributed tracing, a form of event-driven observability for debugging distributed systems, understanding latency outlyers, and delivering "white box" analytics. Full Article
tribute Episode 368: Bryan Helmig on Managing Distributed Teams By traffic.libsyn.com Published On :: Thu, 30 May 2019 23:58:16 +0000 The use of distributed and remote software teams have grown dramatically in the past five years, presenting new challenges for managers and engineers alike. Bryan Helmig talks about the best practices his company, Zapier, uses to manage remote software... Full Article
tribute Episode 377: Heidi Howard on Distributed Consensus By traffic.libsyn.com Published On :: Tue, 20 Aug 2019 20:29:28 +0000 Heidi Howard, a researcher in the field of distributed systems, discusses distributed consensus. Heidi explains when we need it, when we don't need and the algorithms we use to achieve it. Full Article
tribute Episode 406: Torin Sandall on Distributed Policy Enforcement By traffic.libsyn.com Published On :: Tue, 14 Apr 2020 22:58:26 +0000 Torin Sandall of Styra and Open Policy Agent discussed OPA and policy engines and how they can benefit software projects security and compliance. Host Justin Beyer spoke with Sandall about the benefits of removing authorization logic from your application... Full Article
tribute Episode 470: L. Peter Deutsch on the Fallacies of Distributed Computing By traffic.libsyn.com Published On :: Tue, 27 Jul 2021 18:23:06 +0000 L Peter Deutsch of Aladdin Enterprises and formerly of Sun Microsystems joined host Jeff Doolittle to discuss the fallacies of distributed computing. Peter retold the history and origin of the fallacies and how they have been addressed over... Full Article
tribute Episode 487: Davide Bedin on Dapr Distributed Application Runtime By traffic.libsyn.com Published On :: Tue, 23 Nov 2021 19:22:20 +0000 Davide Bedine, a cloud solution architect at Microsoft and professional Dapr enthusiast joined host Jeff Doolittle to discuss his book, Practical Microservices with Dapr and .NET. Dapr, the Distributed Application Runtime, simplifies cloud-native... Full Article
tribute Episode 502: Omer Katz on Distributed Task Queues Using Celery By se-radio.net Published On :: Fri, 11 Mar 2022 03:04:42 +0000 Omer Katz, a software consultant and core contributor to the Celery discusses the Celery task processing framework with host Nikhil Krishna. We discuss in depth, the Celery task processing framework, it's architecture and the underlying messaging... Full Article
tribute SE Radio 560: Sugu Sougoumarane on Distributed SQL with Vitess By se-radio.net Published On :: Wed, 19 Apr 2023 20:46:00 +0000 Sugu Sougoumarane discusses how to face the challenges of horizontally scaling MySQL databases through the Vitess distribution engine and Planetscale, a service built on top of Vitess. The journey began with the growing pains of scale at YouTube around the time of Google’s acquisition of the video service. This episode explores ideas about topology management, sharding, Paxos, connection pooling, and how Vitess handles large transactions while abstracting complexity from the application layer. Full Article
tribute SE Radio 578: Ori Mankali on Secrets Management using Distributed Fragments Cryptography By se-radio.net Published On :: Tue, 22 Aug 2023 21:42:00 +0000 In this episode, Ori Mankali, senior VP of engineering at cloud security startup Akeyless, speaks with SE Radio’s Nikhil Krishna about secrets management and the innovative use of distributed fragment cryptography (DFC). In the context of enterprise IT, 'secrets’ are crucial for authentication in providing access to internal applications and services. Ori describes the unique challenges of managing these sensitive data, particularly given the complexities of doing so on a large scale in substantial organizations. They discuss the necessity for a secure system for managing secrets, highlighting key features such as access policies, audit capabilities, and visualization tools. Ori introduces the concept of distributed fragment cryptography, which boosts security by ensuring that the entire secret is never known to any single entity. The episode explores encryption and decryption and the importance of key rotation, as they consider the challenges and potential solutions in secrets management. Full Article
tribute SE Radio 592: Jaxon Repp on Distributed Data Infrastructure By se-radio.net Published On :: Thu, 30 Nov 2023 00:57:00 +0000 Jaxon Repp of HarperDB speaks with Brijesh Ammanath about distributed data infrastructure, including what it is and why it's important. They discuss the key factors that make distributed data infrastructure attractive, as well as challenges to implementing it. The episode explores the architecture and design principles, the key security considerations, and the transition factors for distributed data Infrastructure. Brought to you by IEEE Computer Society and IEEE Software. Full Article
tribute Driving Distributed Energy with Smart Networks By electrical-engineering-portal.com Published On :: Fri, 03 Jan 2014 05:39:48 +0000 The smart network will set up a virtuous cycle for distributed generators and energy storage devices. It will grow the market by opening up more niches where distributed energy is economically competitive. This growth will lead to economies of scale... Read more The post Driving Distributed Energy with Smart Networks appeared first on EEP - Electrical Engineering Portal. Full Article Energy and Power Smart Grid clean energy distributed energy energy resources energy technologies smart network smart networks utilities
tribute Coach's Corner: Structure Contributes to Synergy | Team Building Pt. 13 By www.randrmagonline.com Published On :: Tue, 13 Feb 2018 14:43:15 -0500 We are into the 13th episode of Dan and Art's series on team building! This week, they're talking about structure and synergy in your company, and within your team. Full Article
tribute James Bond Tribute Artwork By illustrated007.blogspot.com Published On :: Sun, 02 Aug 2020 15:28:00 +0000 "Death, Instead of Cartier" - “Octopussy” tribute artwork by Gerald WadsworthMore of his work here: www.jamesbondart.com Full Article Art: Tributes Title: Octopussy
tribute Live and Let Die Tribute Artwork By illustrated007.blogspot.com Published On :: Sat, 02 Jan 2021 15:28:00 +0000 Tribute artwork for "Live and Let Die - Harlem - A Mecca for Voodoo, Jazz & Jive” by Gerry Wadsworthwww.jamesbondart.com Full Article Art: Tributes Title: Live And Let Die
tribute Casino Royale Art Tribute By illustrated007.blogspot.com Published On :: Sat, 30 Jan 2021 09:07:00 +0000 Illustration for Casino Royale Full Article Art: Tributes
tribute James Bond Tribute Art Magazine By illustrated007.blogspot.com Published On :: Sat, 30 Oct 2021 13:35:00 +0000 Issue 4 of "Layered Butter" - a magazine dedicated to cinema and alternative art. This issue is about James Bond. Full Article Art: Tributes Books: Magazines
tribute [ M.3020 (2011) Amendment 1 (07/14) ] - Indication of naming attribute in analysis template By www.itu.int Published On :: Tue, 25 Nov 2014 15:53:00 GMT Indication of naming attribute in analysis template Full Article
tribute HSTP.DLT-RF - Distributed ledger technologies: Regulatory framework By www.itu.int Published On :: Wed, 06 Nov 2019 11:41:50 GMT HSTP.DLT-RF - Distributed ledger technologies: Regulatory framework Full Article
tribute HSTP.DLT-UC - Distributed ledger technologies: Use cases By www.itu.int Published On :: Thu, 07 Nov 2019 14:15:10 GMT HSTP.DLT-UC - Distributed ledger technologies: Use cases Full Article
tribute Security aspects of distributed ledger technologies By www.itu.int Published On :: Wed, 14 Sep 2022 16:46:14 GMT Security aspects of distributed ledger technologies Full Article
tribute DSTR-IoT-DLT-Accounting - Accounting and billing aspects in Internet of Things (IoT) ecosystem and integrated approach using Distributed Ledger Technology (DLT) By www.itu.int Published On :: Wed, 07 Jun 2023 17:55:52 GMT DSTR-IoT-DLT-Accounting - Accounting and billing aspects in Internet of Things (IoT) ecosystem and integrated approach using Distributed Ledger Technology (DLT) Full Article
tribute TR.x509ac4sc - A use case of X.509 Attribute Certificate for Supply Chain By www.itu.int Published On :: Fri, 15 Mar 2024 15:33:30 GMT TR.x509ac4sc - A use case of X.509 Attribute Certificate for Supply Chain Full Article
tribute TR.qs-dlt - Guidelines for quantum-safe distributed ledger technology systems By www.itu.int Published On :: Thu, 18 Jul 2024 08:11:44 GMT TR.qs-dlt - Guidelines for quantum-safe distributed ledger technology systems Full Article
tribute HSTP-DLT-CG - Construction guidelines for city-level distributed ledger technology (DLT) infrastructure By www.itu.int Published On :: Thu, 18 Jul 2024 08:32:13 GMT HSTP-DLT-CG - Construction guidelines for city-level distributed ledger technology (DLT) infrastructure Full Article
tribute [ F.747.10 (01/22) ] - Requirements of distributed ledger systems for secure human factor services By www.itu.int Published On :: Wed, 06 Apr 2022 11:24:00 GMT Requirements of distributed ledger systems for secure human factor services Full Article
tribute [ F.751.4 (03/22) ] - General framework for distributed ledger technology (DLT)-based invoices By www.itu.int Published On :: Wed, 25 May 2022 08:25:00 GMT General framework for distributed ledger technology (DLT)-based invoices Full Article
tribute [ F.751.3 (03/22) ] - Requirements for change management in distributed ledger technology (DLT)-based decentralized applications By www.itu.int Published On :: Wed, 25 May 2022 08:34:00 GMT Requirements for change management in distributed ledger technology (DLT)-based decentralized applications Full Article
tribute [ F.751.7 (12/22) ] - Functional assessment methods for distributed ledger technology platforms By www.itu.int Published On :: Wed, 25 Jan 2023 16:16:00 GMT Functional assessment methods for distributed ledger technology platforms Full Article
tribute [ F.751.5 (12/22) ] - Requirements for distributed ledger technology-based power grid data management By www.itu.int Published On :: Tue, 21 Mar 2023 11:57:00 GMT Requirements for distributed ledger technology-based power grid data management Full Article
tribute [ F.748.21 (12/22) ] - Requirements and framework for feature-based distributed intelligent systems By www.itu.int Published On :: Fri, 24 Mar 2023 16:10:00 GMT Requirements and framework for feature-based distributed intelligent systems Full Article
tribute [ F.751.6 (12/22) ] - Performance assessment methods for distributed ledger technology platforms By www.itu.int Published On :: Fri, 24 Mar 2023 16:11:00 GMT Performance assessment methods for distributed ledger technology platforms Full Article
tribute [ L.1205 (12/16) ] - Interfacing of renewable energy or distributed power sources to up to 400 VDC power feeding systems By www.itu.int Published On :: Mon, 25 Nov 2019 14:39:00 GMT Interfacing of renewable energy or distributed power sources to up to 400 VDC power feeding systems Full Article
tribute Leveraging GPO to Distribute User- and Computer Certificate By lostintransit.se Published On :: Thu, 07 Nov 2024 07:31:14 +0000 The use of Group Policy Objects (GPO) can be really powerful in a Windows environment. In this post we’re going to leverage GPO to distribute certificates to the user and computer as well as enabling the 802.1X supplicant. First, let’s Full Article ISE 802.1X Certificate
tribute SETU researchers contribute to NASA space mission By www.siliconrepublic.com Published On :: Thu, 07 Nov 2024 16:44:38 +0000 The mission includes studies of solar wind, a radiation-tolerant moss, spacecraft materials, and a cold-welding experiment for space applications. Read more: SETU researchers contribute to NASA space mission Full Article Innovation International Space Station NASA South East Technological University space space-tech SpaceX
tribute Arecibo’s Powerful Radar May Have Contributed to the Telescope’s Demise By skyandtelescope.org Published On :: Fri, 08 Nov 2024 13:00:00 +0000 The Arecibo Observatory’s radar system may have produced currents that weakened the zinc sockets holding the cables in place, new report says. The post Arecibo’s Powerful Radar May Have Contributed to the Telescope’s Demise appeared first on Sky & Telescope. Full Article Astronomy & Observing News Professional Telescopes arecibo
tribute The Inlander teamed up with a Rogers art teacher to paint a tribute to 2020 grads in Riverfront Park By www.inlander.com Published On :: Fri, 22 May 2020 12:52:00 -0700 As a general rule, if you start spray-painting Riverfront Park, Riverfront Park gets mad at you… Full Article News/Local News
tribute Rufus Wainwright to Stage Special Judy Garland Tribute Concert to Mark Her 99th Birthday By www.aceshowbiz.com Published On :: Sat, 01 May 2021 09:00:01 +0000 The musician behind 2007's 'Rufus Does Judy at Carnegie Hall' will stream his digital performance from Capitol Studios in Los Angeles where he is joined by Kristin Chenoweth and Renee Zellweger. Full Article music Rufus Wainwright Judy Garland;Kristin Chenoweth;Renee Zellweger
tribute Lamar Odom Pens Touching Tribute to Late Father Joe By www.aceshowbiz.com Published On :: Tue, 04 May 2021 09:21:32 +0000 In his Instagram post, the retired basketball player also gives a special shoutout to his rumored girlfriend Karlie Redd, thanking her for 'having this picture made of me and my father.' Full Article celebrity Lamar Odom
tribute Mother’s Day tribute to cancer charity By thebirminghampress.com Published On :: Sat, 30 Mar 2019 00:01:03 +0000 "Without Cure Leukaemia my daughter would not be here for Mother’s Day." Full Article Charities Health Medicine
tribute Paying tribute to Jack By thebirminghampress.com Published On :: Wed, 12 Jan 2022 23:20:11 +0000 Community tribute to Jack Dromey MP. Full Article Community Politics Erdington Covid-19 Task Force Jack Dromey