Expertos hablaron de las posibilidades de la prolongación del conflicto, de cómo se ha alterado el panorama geopolítico y de lo que viene en la reconstrucción.

Panelistas creen que estas guerras ponen en jaque las instituciones internacionales y la protección de los derechos humanos.

En 10 AM Hoy por Hoy de Caracol Radio estuvo el ‘Guajiro’, un exmilitar colombiano en Ucrania, que llegó a ese país el pasado 18 de enero y se enlistó en el batallón 59 hispano, para hablar sobre la situación que se vive ´por la guerra en este territorio.

Iranian, Russian Card Payment Systems 'Officially Linked': Tehran Via The Cradle Iranian and Russian card payment systems were formally linked this week, coming as the two nations have been working together to circumvent economic sanctions imposed by Washington and the west. The announcement…

The Iranian threat actor known as TA455 has been observed taking a leaf out of a North Korean hacking group's playbook to orchestrate its own version of the Dream Job campaign targeting the aerospace industry by offering fake jobs since at least September 2023. "The campaign distributed the SnailResin malware, which activates the SlugResin backdoor," Israeli cybersecurity company ClearSky said

The US military has carried out strikes against targets in Syria in what the United States Central Command (CENTCOM) said was a response to recent attacks on US forces by "Iranian-aligned targets" in the country.

Waiting is the hardest part. In the fall of 2023, HPCwire wrote about the new diverging Xeon processor strategy from Intel. Instead of a on-size-fits all approach; Intel has opted […]

The post Granite Rapids HPC Benchmarks: I’m Thinking Intel Is Back (Updated) appeared first on HPCwire.

Donna M. Wilcock
May 1, 2003; 23:3745-3751
Development Plasticity Repair

Low-intensity transcranial focused ultrasound stimulation (TUS) is a novel technique for noninvasive brain stimulation (NIBS). TUS delivered in a theta (5 Hz) burst pattern (tbTUS) induces plasticity in the human primary motor cortex (M1) for 30–60 min, showing promise for therapeutic development. Metaplasticity refers to activity-dependent changes in neural functions governing synaptic plasticity; depotentiation is the reversal of long-term potentiation (LTP) by a subsequent protocol with no effect alone. Metaplasticity can enhance plasticity induction and clinical efficacy of NIBS protocols. In our study, we compared four NIBS protocol combinations to investigate metaplasticity on tbTUS in humans of either sex. We delivered four interventions: (1) sham continuous theta burst stimulation with 150 pulses (cTBS150) followed by real tbTUS (tbTUS only), (2) real cTBS150 followed by sham tbTUS (cTBS only), (3) real cTBS150 followed by real tbTUS (metaplasticity), and (4) real tbTUS followed by real cTBS150 (depotentiation). We measured motor-evoked potential amplitude, short-interval intracortical inhibition, long-interval intracortical inhibition, intracortical facilitation (ICF), and short-interval intracortical facilitation before and up to 90 min after plasticity intervention. Plasticity effects lasted at least 60 min longer when tbTUS was primed with cTBS150 compared with tbTUS alone. Plasticity was abolished when cTBS150 was delivered after tbTUS. cTBS150 alone had no significant effect. No changes in M1 intracortical circuits were observed. Plasticity induction by tbTUS can be modified in manners consistent with homeostatic metaplasticity and depotentiation. This substantiates evidence that tbTUS induces LTP-like processes and suggests that metaplasticity can be harnessed in the therapeutic development of TUS.

Words offer a unique opportunity to separate the processing mechanisms of object subcomponents from those of the whole object, because the phonological or semantic information provided by the word subcomponents (i.e., sublexical information) can conflict with that provided by the whole word (i.e., lexical information). Previous studies have revealed some of the specific brain regions and temporal information involved in sublexical information processing. However, a comprehensive spatiotemporal neural network for sublexical processing remains to be fully elucidated due to the low temporal or spatial resolutions of previous neuroimaging studies. In this study, we recorded stereoelectroencephalography signals with high spatial and temporal resolutions from a large sample of 39 epilepsy patients (both sexes) during a Chinese character oral reading task. We explored the activated brain regions and their connectivity related to three sublexical effects: phonological regularity (whether the whole character's pronunciation aligns with its phonetic radical), phonological consistency (whether characters with the same phonetic radical share the same pronunciation), and semantic transparency (whether the whole character's meaning aligns with its semantic radical). The results revealed that sublexical effects existed in the inferior frontal gyrus, precentral and postcentral gyri, temporal lobe, and middle occipital gyrus. Additionally, connectivity from the middle occipital gyrus to the postcentral gyrus and from postcentral gyrus to the fusiform gyrus was associated with the sublexical effects. These findings provide valuable insights into the spatiotemporal dynamics of sublexical processing and object recognition in the brain.

With hundreds of new uranium mining claims filed within just a few miles of Grand Canyon National Park, a proposed new law would close the area to mining development and prevent radioactive contamination from discharging into the park

US forces on Tuesday carried out strikes against targets linked to an Iranian-backed groups in Syria in response to a rocket attack on Washington's troops in the country, the US military said.

Abdul Ghafoor Noorani, eminent constitutional expert, lawyer and author, died today at the age of 93. A noted scholar on Jammu and Kashmir, his absence is being felt in the Union Territory, where many are mourning him.

washington — The U.S. military said Monday that it had carried out strikes against nine targets associated with Iranian groups in Syria.  In a statement, the U.S. military said the strikes were made against two locations in Syria and were a response to several attacks on U.S. personnel in Syria in the past 24 hours.  The U.S. has occasionally carried out strikes against targets linked to Iran in both Iraq and Syria. In February, the U.S. launched airstrikes in Iraq and Syria against more than 85 targets linked to Iran's Islamic Revolutionary Guard Corps and militias it backs, in retaliation for a deadly attack on U.S. troops.  "These strikes will degrade the Iranian backed groups' ability to plan and launch future attacks on U.S. and coalition forces," the U.S. military said after the most recent strikes.  The U.S. has 900 troops in Syria and 2,500 in neighboring Iraq, on a mission to advise and assist local forces trying to prevent a resurgence of Islamic State, which in 2014 seized large swaths of both countries but was later defeated.  The U.S. has sent warships and fighter aircraft to the region since the Israel-Hamas conflict erupted on October 7, 2023, to try to deter Iran and Iran-backed groups from getting involved in the conflict.  U.S. forces have also helped shoot down projectiles that Iran launched toward Israel this year. 

Netanyahu urged Iranians to imagine their free lives without 'the tyrants of Tehran' in an unusual English message.

According to reports, Amir Nasr-Azadani, a soccer player from Iran may face execution for participating in ongoing anti-government protests in the country.

How can Khamenei's "shadow empire" deteriorate?

High-level meetings in Tehran signal deepening Iran-Iraq security cooperation, while Iran simultaneously advances its regional agenda through talks with Turkey, Russia, and Lebanon.

The strikes were in response to attacks on US personnel over the past 24 hours, CENTCOM reported.

BACKGROUND AND PURPOSE:

Intracranial epidermoids temporal bone cholesteatomas, and head and neck epidermal inclusion cysts are typically slow-growing, benign conditions arising from ectodermal tissue. They exhibit increased signal on DWI. While much of the imaging literature describes these lesions as showing diffusion restriction, we investigated these qualitative signal intensities and interpretations of restricted diffusion with respect to normal brain structures. This study aimed to quantitatively evaluate the ADC values and histogram features of these lesions.

BACKGROUND AND PURPOSE:

Periprocedural intracranial hemorrhage is one of common complications after stent placement for symptomatic intracranial atherosclerotic stenosis. This study was conducted to demonstrate predictors and long-term outcomes of periprocedural intracranial hemorrhage after stent placement for symptomatic intracranial atherosclerotic stenosis.

BACKGROUND AND PURPOSE:

Reocclusion after treatment is a concern in endovascular therapy for isolated intracranial atherothrombotic stroke-related large-vessel occlusion (AT-LVO). However, the optimal endovascular therapy technique for AT-LVO has not yet been investigated. This study evaluated the optimal endovascular therapy technique for AT-LVO in a real-world setting.

BACKGROUND AND PURPOSE:

Prediction of aneurysm instability is crucial to guide treatment decisions and to select appropriate patients with unruptured intracranial aneurysms (IAs) for preventive treatment. High-resolution 4D MR flow imaging and 3D quantification of aneurysm morphology could offer insights and new imaging markers for aneurysm instability. In this cross-sectional study, we aim to identify 4D MR flow imaging markers for aneurysm instability by relating hemodynamics in the aneurysm sac to 3D morphologic proxy parameters for aneurysm instability.

Inositol 1,4,5-triphosphate receptor type 1 (ITPR1) is an endoplasmic reticulum–bound intracellular inositol triphosphate receptor involved in the regulation of intracellular calcium. Pathogenic variants in ITPR1 are associated with spinocerebellar ataxia (SCA) types 15/16 and 29 and have recently been implicated in a facial microsomia syndrome. In this report, we present a family with three affected individuals found to have a heterozygous missense c.800C > T (predicted p.Thr267Met) who present clinically with a SCA29-like syndrome. All three individuals presented with varying degrees of ataxia, developmental delay, and apparent intellectual disability, as well as craniofacial involvement—an uncommon finding in patients with SCA29. The variant was identified using clinical exome sequencing and validated with Sanger sequencing. It is presumed to be inherited via parental germline mosaicism. We present our findings to provide additional evidence for germline mosaic inheritance of SCA29, as well as to expand the clinical phenotype of the syndrome.

May 24, 2024

Mohammad Tabaar writes that former Iranian President Raisi will be remembered for putting the country on the right path after a series of presidents who challenged the supreme leader's vision. He will be memorialized for positioning Iran as a nuclear threshold state and establishing it as a rising power—and for doing so not despite external pressure, but because of it.

Shot from village Timila in Ranikhet Tehsil of Uttarakhand

A potential connection has been found between certain Gastrointestinal (GI) syndromes and the formation and rupture of intracranial (brain) aneurysms,

Alia shared a candid picture with Raha and Ranbir as her daughter turned two. The doting parents threw a jungle themed party/

1. Vide order dated 29.08.2024 Prakash Grih Nirman Sehkari Samiti Maryadit was directed to file the reply. Learned counsel representing respondent/ Prakash Grih Nirman Sehkari Samiti Maryadit has submitted that due to technical reasons reply has not been uploaded. The same may be filed within two weeks with copy to the opposite parties.

2. In the meantime, learned counsels for the State and BMC are directed to trace the map, revenue record with regard to allotment/allocation of green belt in the Map as approved.

3. Applicant present in person has submitted that the present matter relates only to the cutting of trees. MPPCB has issued notice to the Prakash Grih OA No. 139/2023(CZ) Krishnarani Agrawal vs. State of Madhya Pradesh & Ors. Nirman Sehkari Samiti Maryadit with assessment of environmental compensation but the same has not been replied till date. State PCB is directed to finalise the matter and report within two weeks.

By way of this order, I intend to dispose off aforesaid-captioned appeals. These appeals involve similar question of law in the background of identical set of facts.

1 of 9 Neutral Citation No:=2024:PHHC:145543 other connected cases

2. For brevity, the facts are being culled out from from FAO No.1112 of 1988.

3. Instant appeal is directed against judgment dated 26th of August, 2022 passed by Sub Judge, 1st Class, Phagwara exercising powers as ESI Court under ESI Act, 1948 whereby the petition filed under Section 75-78 of the ESI Act, 1948 by the respondent has been allowed.

4. Recovery certificate under Section 45-A was issued and attachment proceedings were initiated against the respondent through Assistant Collector 2nd Grade, Phagwara for recovery of Rs.6690-95 paise. Respondent challenged the demand before ESI Court. It was claimed that the demand raised by the ESI Corporation was based on adhoc assessment without any survey. The demand has been raised w.r.t. 132 KV Sub Station, Phagwara. The same does not fall within the purview of ESI Act as the strength of the staff is only three in number. The staff employed for maintenance like Mali, Sweeper at the Sub Station are on the roles of XEN D/S and not on the roles of KV Sub Station. It was thus claimed that the respondent was not liable to pay any amount towards ESI contribution.