malaria

CRISPR/Cas9 Tool may Help Suppress Malarial Parasites in Mosquitoes

Using CRISPR/Cas9, a gene editing tool gene, the FREP1 gene can be inactivated to reduce mosquitoes vulnerability to Plasmodium parasite, a genus that causes malaria in humans.




malaria

Common Toiletry Antimicrobial Compound Prevents Malarial Spread

Target genes in the malaria parasite can be inhibited by triclosan, an antimicrobial compound used in soap, toothpaste, deodorant and many other products, finds a new study.




malaria

New Malaria Vaccine Candidate Revealed

A promising new strategy for combating malaria, a mosquito-borne parasite that claims nearly a half-million lives each year has been discovered by researchers.






malaria

Italy Raises Contribution to Fight TB, Malaria, AIDS

Italy's 15 percent rise in its contribution to the United Nations to fight AIDS, tuberculosis, and malaria shows its commitment to the health sector, says Foreign Minister Emanuela Del Re.




malaria

One Step Closer to Eradicating Malaria: Study

In a low malaria-endemic setting, reactive focal mass drug administration and reactive focal vector control such as insecticide spraying implemented alone




malaria

Combination Therapy Benefits Pregnant Women With Malaria More

Artemether-lumefantrine (AL) and other artemisinin-based combination therapies (ACTs) were significantly more effective than quinine. The study details




malaria

Transmission Risk of Malaria is Highest in Early Evening

Mosquitoes are most likely to transmit malaria in the early evening, when people are exposed, then at midnight, when people are protected by bed nets, or in the morning, according to the new study.




malaria

More Antimalarial Artemisinin can Be Extracted from Chinese Shrubs

iArtemisia annua/i herb has now been genetically engineered to produce more Artemisinin. Anti-Malarial benefits of Artemisinin compound can only be




malaria

Acai Berry Derivatives Treat Malaria in Mice

Acai berry extracts can reduce parasites in the blood and prolong the survival of malarial mice, according to the study published in iACS Omega/i.




malaria

Nanovectors Can Enhance The Administration Of Combined Antimalarial Drugs

Combining different two drugs with different properties into nanovesicles surrounded by antibodies can hugely improve their delivery and efficiency. .




malaria

Covid-19 focus threatens precarious malaria progress

Pandemic could set back the fight against malaria by 20 years, with Africa hit worst




malaria

How to tackle malaria, by a sufferer turned scientist

Local drug research and joined-up thinking are needed to deliver results on the ground




malaria

A malaria drug can protect fetuses from Zika Virus

Researchers at Washington University School of Medicine have found that a malaria drug blocks Zika from infecting the fetus. It is the first sign of a drug that could prevent Zika birth defects.




malaria

CRAIG BROWN: Malaria? I don't even know her. All your health questions answered by Dr Donald 

CRAIG BROWN: Q: I have an ingrowing toenail. What should I do about it, Dr Donald? DR DONALD SAYS: Nobody knows ingrowing toenails like I do, and that's a fact.




malaria

CRAIG BROWN: Malaria? I don't even know her. All your health questions answered by Dr Donald 

CRAIG BROWN: Q: I have an ingrowing toenail. What should I do about it, Dr Donald? DR DONALD SAYS: Nobody knows ingrowing toenails like I do, and that's a fact.




malaria

Scientists identify microbe that stops mosquitoes catching or spreading malaria

The malaria-blocking bug, Microsporidia MB, was found by University of Glasgow scientists in the gut and genitals of mosquitoes living on the shores of Lake Victoria in Kenya.




malaria

Australians urged NOT to use anti-malaria drug which Donald Trump described as cure against COVID-19

More than 6,000 tablets of hydroxychloroquine have been seized by the Australian Border Force since January.




malaria

This monsoon, Assam takes on malaria


The heavy rains of the south-west monsoon are a few weeks away and malaria usually follows, in Assam. The state has 20 per cent of malaria deaths in India, but this time, doctors say they have taken substantive measures. Ratna Bharali Talukdar reports.




malaria

New Study Finds No Benefit from Malaria Drug HCQ for Coronavirus Treatment

Hydroxychloroquine did not lower the risk of dying or needing a breathing tube in a comparison that involved nearly 1,400 patients treated at Columbia University in New York, researchers reported Thursday in the New England Journal of Medicine.




malaria

World Immunization Week: 9 Malaria Complications You Need To Be Aware Of

According to a 2017 WHO report, India ranks fourth in infections and deaths caused by malaria. Malaria is a mosquito-borne disease and children, pregnant women and travellers are more prone to the disease. The female Anopheles mosquito transfers Plasmodium parasites




malaria

[ASAP] A Chemically Stable Fluorescent Mimic of Dihydroartemisinin, Artemether, and Arteether with Conserved Bioactivity and Specificity Shows High Pharmacological Relevance to the Antimalarial Drugs

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00430




malaria

WIRED by Design - Designing a Brand to Help Kill Malaria

Ije Nwokorie at WIRED by Design, 2014. In partnership with Skywalker Sound, Marin County, CA. To learn more visit: live.wired.com




malaria

Fighting malaria, one mosquito at a time




malaria

Science Podcast - 100 years of crystallography, linking malaria and climate, and a news roundup (7 Mar 2014)

Celebrating crystallography's centennial; how climate pushes malaria uphill; roundup of daily news with David Grimm.




malaria

Podcast: Recognizing the monkey in the mirror, giving people malaria parasites as a vaccine strategy, and keeping coastal waters clean with seagrass

This week, we chat about what it means if a monkey can learn to recognize itself in a mirror, injecting people with live malaria parasites as a vaccine strategy, and insect-inspired wind turbines with Online News Editor David Grimm. And Joleah Lamb joins Alexa Billow to discuss how seagrass can greatly reduce harmful microbes in the ocean—protecting people and corals from disease. Read the research.   Listen to previous podcasts.   [Image: peters99/iStock; Music: Jeffrey Cook]




malaria

Portable and benchtop Raman spectrometers coupled to cluster analysis to identify quinine sulfate polymorphs in solid dosage forms and antimalarial drug quantification in solution by AuNPs-SERS with MCR-ALS

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00693A, Paper
Sarmento J. Mazivila, Helena I. S. Nogueira, Ricardo N. M. J. Páscoa, David S. M. Ribeiro, João L. M. Santos, João M. M. Leitão, Joaquim C. G. Esteves da Silva
Raman spectrometers coupled to cluster analysis were able to identify two polymorphs of quinine sulfate in solid dosage forms. Gold nanoparticles-surface-enhanced Raman scattering with MCR-ALS was used to antimalarial drug quantification in solution.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




malaria

Visible-light mediated oxidative ring expansion of anellated cyclopropanes to fused endoperoxides with antimalarial activity

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00168F, Research Article
Simon Budde, Felix Goerdeler, Johannes Floß, Peter Kreitmeier, Elliot F. Hicks, Oren Moscovitz, Peter H. Seeberger, Huw M. L. Davies, Oliver Reiser
Hetero- and carbocyclic anellated cyclopropanes were converted in one step by a visible light induced photooxidation to their corresponding polycyclic endoperoxides, which show promising antimalarial activity.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




malaria

Ultrafast synthesis of 2-(benzhydrylthio)benzo[d]oxazole, an antimalarial drug, via an unstable lithium thiolate intermediate in a capillary microreactor

React. Chem. Eng., 2020, 5,849-852
DOI: 10.1039/D0RE00038H, Communication
Bandaru T. Ramanjaneyulu, Shinde Vidyacharan, Gwang-Noh Ahn, Dong-Pyo Kim
We present an ultrafast approach for the synthesis of 2-(benzhydrylthio)benzo[d]oxazole, an antimalarial drug, in 75% yield from benzo[d]oxazole-2-thiol and benzhydryl bromide via an unstable lithium thiolate intermediate in the presence of n-BuLi.
The content of this RSS Feed (c) The Royal Society of Chemistry




malaria

Biosafety Concerns Involving Genetically Modified Mosquitoes to Combat Malaria and Dengue in Developing Countries

Interview with Lawrence O. Gostin, JD, author of Biosafety Concerns Involving Genetically Modified Mosquitoes to Combat Malaria and Dengue in Developing Countries




malaria

Malaria, labor supply, and schooling in Sub-Sahara Africa




malaria

Malaria in prehistoric sardinia (italy) :




malaria

Use of the Quinoline anti-malarial drugs Mefloquine and Tafenoquine in the Australian Defence Force / The Senate, Foreign Affairs, Defence and Trade References Committee

Australia. Parliament. Senate. Foreign Affairs, Defence and Trade References Committee, author, issuing body




malaria

World Malaria Day 2020: Does malaria continue to be a threat during Covid-19 outbreak?




malaria

Some preventive measures for malaria you can follow by staying indoors